专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5653756A Closed porous chambers for implanting tissue in a host 失效
标题翻译：用于在组织中植入组织的封闭多孔室
公开(公告)号：US5653756A
公开(公告)日：1997-08-05
申请号：US300173
申请日：1994-09-02
申请人： Robert A. Clarke , Robin G. Pauley , Ronald S. Hill , James H. Brauker , Shmuel Sternberg , Daniel R. Boggs
发明人： Robert A. Clarke , Robin G. Pauley , Ronald S. Hill , James H. Brauker , Shmuel Sternberg , Daniel R. Boggs
IPC分类号： A61B5/00 , A61F2/02 , A61K9/00 , A61L27/38 , A61L27/56 , A61L29/00 , A61L29/14
CPC分类号： A61K9/0024 , A61F2/022 , A61L27/38 , A61L27/56 , A61L29/005 , A61L29/146 , A61B5/14532 , Y10S623/901
摘要： Improved Implant assemblies and methodologies provide immuno-protection for implanted allografts, xenografts, and isografts. The assemblies and methodologies establish an improved chamber for holding the implanted cells. The chambers include first and second wall elements and an intermediate sealing element. The first and second wall elements overlie an open area in the sealing member to form a chamber for holding cells for implantation. A sealed region is created between the wall elements and the sealing element body to close the chamber. In one arrangement, the sealed region is created by means of a sonic weld made while the implanted cells are present in the chamber. In another arrangement, the sealed region is created by means of applying an external force to compress the peripheral edges of the wall elements and the sealing element together while the implanted cells are present in the chamber.
摘要翻译：改进的植入物组件和方法为植入的同种异体移植物，异种移植物和同种移植物提供免疫保护。组件和方法建立了用于保持植入细胞的改进室。这些室包括第一和第二壁元件和中间密封元件。第一和第二壁元件覆盖在密封构件中的开放区域以形成用于保持用于植入的细胞的室。在壁元件和密封元件主体之间产生密封区域以关闭室。在一种布置中，通过在植入的细胞存在于腔室中时进行的声波焊接来产生密封区域。在另一种布置中，通过施加外力来将密封区域产生，以将壁元件和密封元件的周边边缘压缩在一起，同时植入的电池存在于腔室中。

2. 发明授权

US5344454A Closed porous chambers for implanting tissue in a host 失效
标题翻译：用于在组织中植入组织的封闭多孔室
公开(公告)号：US5344454A
公开(公告)日：1994-09-06
申请号：US861952
申请日：1992-04-01
申请人： Robert A Clarke , Robin G. Pauley , Ronald S. Hill , James H. Brauker , Shmuel Sternberg , Daniel R. Boggs
发明人： Robert A Clarke , Robin G. Pauley , Ronald S. Hill , James H. Brauker , Shmuel Sternberg , Daniel R. Boggs
IPC分类号： A61B5/00 , A61F2/02 , A61K9/00 , A61L27/38 , A61L27/56 , A61L29/00 , A61L29/14 , A61F2/54 , A61F13/00 , A61K9/22
CPC分类号： A61K9/0024 , A61F2/022 , A61L27/38 , A61L27/56 , A61L29/005 , A61L29/146 , A61B5/14532 , Y10S623/901
摘要： Improved Implant assemblies and methodologies provide immuno-protection for implanted allografts, xenografts, and isografts. The assemblies and methodologies establish an improved chamber for holding the implanted cells. The chambers include first and second wall elements and an intermediate sealing element. The first and second wall elements overlie an open area in the sealing member to form a chamber for holding cells for implantation. A sealed region is created between the wall elements and the sealing element body to close the chamber. In one arrangement, the sealed region is created by means of a sonic weld made while the implanted cells are present in the chamber. In another arrangement, the sealed region is created by means of applying an external force to compress the peripheral edges of the wall elements and the sealing element together while the implanted cells are present in the chamber.
摘要翻译：改进的植入物组件和方法为植入的同种异体移植物，异种移植物和同种移植物提供免疫保护。组件和方法建立了用于保持植入细胞的改进室。这些室包括第一和第二壁元件和中间密封元件。第一和第二壁元件覆盖在密封构件中的开放区域以形成用于保持用于植入的细胞的室。在壁元件和密封元件主体之间产生密封区域以关闭室。在一种布置中，通过在植入的细胞存在于腔室中时进行的声波焊接来产生密封区域。在另一种布置中，通过施加外力来产生密封区域，以在腔室中存在植入的细胞的同时将壁元件和密封元件的周边边缘压缩在一起。

3. 发明授权

US6060640A Multiple-layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue 失效
标题翻译：用于在宿主组织中植入细胞的多层形成的免疫隔离膜结构
公开(公告)号：US6060640A
公开(公告)日：2000-05-09
申请号：US446210
申请日：1995-05-19
申请人： Robin G. Pauley , Donna L. McLarty , Atul R. Khare , Shmuel Sternberg , Daniel R. Boggs , Steven Neuenfeldt , Mark Jones , James H. Brauker , Laura A. Martinson
发明人： Robin G. Pauley , Donna L. McLarty , Atul R. Khare , Shmuel Sternberg , Daniel R. Boggs , Steven Neuenfeldt , Mark Jones , James H. Brauker , Laura A. Martinson
IPC分类号： A61F2/02 , A61K9/00 , A61L27/38 , C12N5/08 , A61D7/00 , A61M31/00
CPC分类号： A61K9/0024 , A61F2/022 , A61L27/38
摘要： A permeable structure forms a chamber to hold living cells. The structure includes a first permeable region surrounding at least a portion of the chamber having a conformation that, when implanted in host tissue, substantially blocks penetration of host cells into the chamber while permitting solute transport. The structure also includes a second permeable region overlying the first permeable region having a conformation that, when implanted in host tissue, forms a permeable interface with host tissue that permits solute transport. A third permeable region is located between the first and second permeable regions. The third region comprises a solution of polymer material formed in place between the first and second permeable regions. The third permeable region bonds the first and second permeable regions together. The third permeable region also has a conformation that, when implanted in host tissue, permits solute transport between the first and second permeable regions. The third, formed-in-place region bonds the first and second permeable regions together, providing a robust, laminated structure that resists delamination during implantation caused by cellular infiltration into discontinuous spaces between the first and second regions. The third, formed-in-place region can also have a conformation providing an immunoisolation effect. Furthermore, the permeability of the third, formed-in-place membrane is sufficient high that it does not adversely effect the permeability value desired for the overall multiple layer membrane structure.
摘要翻译：可渗透结构形成容纳活细胞的室。所述结构包括围绕所述腔室的至少一部分的第一可渗透区域，其具有当植入宿主组织时基本上阻挡宿主细胞渗入所述腔室同时允许溶质运输的构象。该结构还包括覆盖第一可渗透区域的第二可渗透区域，其具有当植入宿主组织中时形成允许溶质运输的宿主组织的可渗透界面的构象。第三可渗透区域位于第一和第二可渗透区域之间。第三区域包括在第一和第二可渗透区域之间形成的聚合物材料溶液。第三可渗透区域将第一和第二可渗透区域结合在一起。第三可渗透区域还具有当植入宿主组织时允许溶质在第一和第二可渗透区域之间传输的构象。第三个就地区域将第一和第二可渗透区域结合在一起，提供坚固的层压结构，其抵抗由于细胞浸润到第一和第二区域之间的不连续空间而在植入过程中的分层。第三个就地区域也可以具有提供免疫隔离作用的构象。此外，第三成形膜的渗透性足够高，使得其不会对整个多层膜结构所期望的渗透性值产生不利影响。

4. 发明授权

US06899834B2 Composite membranes and methods for making such membranes 有权
标题翻译：复合膜和制造这种膜的方法
公开(公告)号：US06899834B2
公开(公告)日：2005-05-31
申请号：US09997822
申请日：2001-11-30
申请人： Daniel R. Boggs , Shmuel Sternberg , Robin G. Pauley , Donna L. McLarty
发明人： Daniel R. Boggs , Shmuel Sternberg , Robin G. Pauley , Donna L. McLarty
IPC分类号： B01D69/12 , A61M1/36 , B01D69/14 , B01D71/20 , B01D71/30 , B01D71/38 , B01D71/54 , B01J20/28 , B29D33/48
CPC分类号： B01J20/28033 , A61M1/3686 , B01D69/141 , B01J20/28004 , B01J20/28026 , B01J20/28035
摘要： Membranes and methods for making membranes are disclosed. The membranes include a polymeric matrix and a particulate material immobilized within the matrix. The membranes may find particular application in methods and apparatus for removing organic compounds from a biological fluid as part of a pathogen inactivation treatment.
摘要翻译：公开了膜和膜的制造方法。膜包括聚合物基质和固定在基质内的颗粒物质。作为病原体灭活处理的一部分，膜可以特别适用于从生物液体中除去有机化合物的方法和装置。

5. 发明授权

US06908553B1 Composite membrane with particulate matter substantially immobilized therein 失效
标题翻译：复合膜，其中颗粒物质基本上固定在其中
公开(公告)号：US06908553B1
公开(公告)日：2005-06-21
申请号：US09111915
申请日：1998-07-08
申请人： Daniel R. Boggs , Shmuel Sternberg , Robin G. Pauley , Donna L. McLarty
发明人： Daniel R. Boggs , Shmuel Sternberg , Robin G. Pauley , Donna L. McLarty
IPC分类号： B01D69/12 , A61M1/36 , B01D69/14 , B01D71/20 , B01D71/30 , B01D71/38 , B01D71/54 , B01J20/28 , B01D39/00
CPC分类号： B01J20/28033 , A61M1/3686 , B01D69/141 , B01J20/28004 , B01J20/28026 , B01J20/28035
摘要： Membranes and methods for making membranes are disclosed. The membranes include a polymeric matrix and a particulate material immobilized within the matrix. The membranes may find particular application in methods and apparatus for removing organic compounds from a biological fluid as part of a pathogen inactivation treatment.
摘要翻译：公开了膜和膜的制造方法。膜包括聚合物基质和固定在基质内的颗粒物质。作为病原体灭活处理的一部分，膜可以特别适用于从生物液体中除去有机化合物的方法和装置。

6. 发明授权

US6099734A Apparatus, membranes and methods for removing organic compounds from a biological fluid 失效
标题翻译：用于从生物流体中除去有机化合物的装置，膜和方法
公开(公告)号：US6099734A
公开(公告)日：2000-08-08
申请号：US111655
申请日：1998-07-08
申请人： Daniel R. Boggs , Derek J. Hei , Shmuel Sternberg , Robin G. Pauley , Donna L. McLarty
发明人： Daniel R. Boggs , Derek J. Hei , Shmuel Sternberg , Robin G. Pauley , Donna L. McLarty
IPC分类号： B01D61/00 , A61M1/36 , B01D15/00 , B01D69/00 , B01D71/02 , B01D71/16 , B01D71/30 , B01D71/54 , B01J20/28
CPC分类号： B01D69/148 , A61M1/3686 , B01D63/087 , B01D63/14 , B01D65/022 , B01D67/0009 , B01D67/0086 , B01D69/02 , B01D69/10 , B01D69/147 , B01D71/16 , B01D71/30 , B01D71/34 , B01D71/54 , A61M1/02 , B01D2321/346 , B01D2323/42 , B01D2325/38
摘要： Membranes and methods for making membranes are disclosed. The membranes include a polymeric matrix and a particulate material immobilized within the matrix. The membranes may find particular application in methods and apparatus for removing organic compounds from a biological fluid as part of a pathogen inactivation treatment.
摘要翻译：公开了膜和膜的制造方法。膜包括聚合物基质和固定在基质内的颗粒物质。作为病原体灭活处理的一部分，膜可以特别适用于从生物液体中除去有机化合物的方法和装置。

7. 发明授权

US08431086B2 Medical fluid access device with antiseptic indicator 有权
标题翻译：具防腐指标的医用流体通道装置
公开(公告)号：US08431086B2
公开(公告)日：2013-04-30
申请号：US13154848
申请日：2011-06-07
申请人： Kent L. Lurvey , Shmuel Sternberg , Vadim V. Krongauz , Rosa H. Yeh , Robin G. Pauley , Dustin C. Cawthon , Ton That Hai , Lecon L. Woo , Ashok K. Khanna , Birendra K. Lal , Michael Tung-Kiung Ling , William S. Hoerle , Craig L. Sandford , Mark A. Nordhaus , Alexander Savitski , Nicklaus J. Kirichkow , Kenneth Glen Suh , Sivaramakrishnan Krishnamoorthy , Hsinjin E. Yang , Robert A. Clarke
发明人： Kent L. Lurvey , Shmuel Sternberg , Vadim V. Krongauz , Rosa H. Yeh , Robin G. Pauley , Dustin C. Cawthon , Ton That Hai , Lecon L. Woo , Ashok K. Khanna , Birendra K. Lal , Michael Tung-Kiung Ling , William S. Hoerle , Craig L. Sandford , Mark A. Nordhaus , Alexander Savitski , Nicklaus J. Kirichkow , Kenneth Glen Suh , Sivaramakrishnan Krishnamoorthy , Hsinjin E. Yang , Robert A. Clarke
IPC分类号： G01N21/75
CPC分类号： G01N21/78 , A61M39/02 , A61M39/045 , A61M39/16 , A61M39/26 , A61M2039/1033 , A61M2039/1072 , A61M2205/583 , A61M2205/584 , G01N31/22
摘要： A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent.
摘要翻译：公开了一种医疗装置，例如血管通路装置，用于提供对医用流体流路的通路，用于将医用流体引入或取出流路。访问装置包括用于当访问装置已经暴露于防腐剂时提供视觉指示的指示器。

8. 发明申请

US20110236258A1 MEDICAL FLUID ACCESS DEVICE WITH ANTISEPTIC INDICATOR 有权
标题翻译：具有抗菌指示器的医用流体访问装置
公开(公告)号：US20110236258A1
公开(公告)日：2011-09-29
申请号：US13154848
申请日：2011-06-07
申请人： Kent L. Lurvey , Shmuel Sternberg , Vadim V. Krongauz , Rosa H. Yeh , Robin G. Pauley , Dustin C. Cawthon , Ton That Hai , Lecon L. Woo , Ashok K. Khanna , Birendra K. Lal , Michael Tung-Kiung Ling , William S. Hoerle , Craig L. Sandford , Mark A. Nordhaus , Alexander Savitski , Nicklaus J. Kirichkow , Kenneth Glen Suh , Sivaramakrishnan Krishnamoorthy , Hsinjin E. Yang , Robert A. Clarke
发明人： Kent L. Lurvey , Shmuel Sternberg , Vadim V. Krongauz , Rosa H. Yeh , Robin G. Pauley , Dustin C. Cawthon , Ton That Hai , Lecon L. Woo , Ashok K. Khanna , Birendra K. Lal , Michael Tung-Kiung Ling , William S. Hoerle , Craig L. Sandford , Mark A. Nordhaus , Alexander Savitski , Nicklaus J. Kirichkow , Kenneth Glen Suh , Sivaramakrishnan Krishnamoorthy , Hsinjin E. Yang , Robert A. Clarke
IPC分类号： G01N21/78 , G01N21/76
CPC分类号： G01N21/78 , A61M39/02 , A61M39/045 , A61M39/16 , A61M39/26 , A61M2039/1033 , A61M2039/1072 , A61M2205/583 , A61M2205/584 , G01N31/22
摘要： A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent.
摘要翻译：公开了一种医疗装置，例如血管通路装置，用于提供对医用流体流路的通路，用于将医用流体引入或取出流路。访问装置包括用于当访问装置已经暴露于防腐剂时提供视觉指示的指示器。

9. 发明授权

US07981381B2 Medical fluid access device with antiseptic indicator 有权
标题翻译：具防腐指标的医用流体通道装置
公开(公告)号：US07981381B2
公开(公告)日：2011-07-19
申请号：US11780917
申请日：2007-07-20
申请人： Kent L. Lurvey , Shmuel Sternberg , Vadim V. Krongauz , Rosa H. Yeh , Robin G. Pauley , Dustin C. Cawthon , Ton That Hai , Lecon L. Woo , Ashok K. Khanna , Birendra K. Lal , Michael Tung-Kiung Ling , William S. Hoerle , Craig L. Sandford , Mark A. Nordhaus , Alexander Savitski , Nicklaus J. Kirichkow , Kenneth Glen Suh , Sivaramakrishnan Krishnamoorthy , Hsinjin E. Yang , Robert A. Clarke
发明人： Kent L. Lurvey , Shmuel Sternberg , Vadim V. Krongauz , Rosa H. Yeh , Robin G. Pauley , Dustin C. Cawthon , Ton That Hai , Lecon L. Woo , Ashok K. Khanna , Birendra K. Lal , Michael Tung-Kiung Ling , William S. Hoerle , Craig L. Sandford , Mark A. Nordhaus , Alexander Savitski , Nicklaus J. Kirichkow , Kenneth Glen Suh , Sivaramakrishnan Krishnamoorthy , Hsinjin E. Yang , Robert A. Clarke
IPC分类号： G01N21/75
CPC分类号： G01N21/78 , A61M39/02 , A61M39/045 , A61M39/16 , A61M39/26 , A61M2039/1033 , A61M2039/1072 , A61M2205/583 , A61M2205/584 , G01N31/22
摘要： A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent.
摘要翻译：公开了一种医疗装置，例如血管通路装置，用于提供对医用流体流路的通路，用于将医用流体引入或取出流路。访问装置包括用于当访问装置已经暴露于防腐剂时提供视觉指示的指示器。

10. 发明申请

US20080107564A1 MEDICAL FLUID ACCESS SITE WITH ANTISEPTIC INDICATOR 审中-公开
公开(公告)号：US20080107564A1
公开(公告)日：2008-05-08
申请号：US11550643
申请日：2006-10-18
申请人： Shmuel Sternberg , Kent L. Lurvey , Robin G. Pauley , Dustin C. Cawthon , Ton That Hai , Lecon Woo , Ashok K. Khanna , Birendra K. Lal , Michael Tung-Kiung Ling , Vadim V. Krongauz , Rosa H. Yeh , William S. Hoerle , Craig L. Sandford
发明人： Shmuel Sternberg , Kent L. Lurvey , Robin G. Pauley , Dustin C. Cawthon , Ton That Hai , Lecon Woo , Ashok K. Khanna , Birendra K. Lal , Michael Tung-Kiung Ling , Vadim V. Krongauz , Rosa H. Yeh , William S. Hoerle , Craig L. Sandford
IPC分类号： G01N21/78 , A61M5/50
CPC分类号： G01N21/78 , A61M39/02 , A61M39/045 , A61M39/16 , A61M39/26 , A61M2039/1033 , A61M2039/1072 , A61M2205/583 , A61M2205/584 , G01N31/22
摘要： An access device including access site is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式