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1. 发明申请

US20110286953A1 WHITENING AGENT, ANTI-AGING AGENT, AND ANTI-OXIDANT AGENT 审中-公开
标题翻译：白化剂，抗老化剂和抗氧化剂
公开(公告)号：US20110286953A1
公开(公告)日：2011-11-24
申请号：US13138378
申请日：2010-02-03
申请人： Rikako Suzuki , Kiyotaka Hasegawa , Kiyoshi Sato , Tokiya Yokoi , Ken Kusakari
发明人： Rikako Suzuki , Kiyotaka Hasegawa , Kiyoshi Sato , Tokiya Yokoi , Ken Kusakari
IPC分类号： A61K8/97 , A61Q19/08 , A61Q19/02 , A61K36/12 , A61Q19/00
CPC分类号： A61K8/97 , A61K36/11 , A61Q19/02 , A61Q19/08
摘要： [Problem] To provide a whitening agent having a superior skin whitening activity, and having a superior effect in lightening and whitening pigmentation, aging spots, freckles, chloasma, or the like after sunburn, and an antioxidant agent and an anti-aging agent having a superior free radical scavenging ability for preventing and controlling aging in the skin and skin diseases caused by active oxygen (free radicals), and having a high level of safety.[Means for Solving the Problem] An extract of Psilotum spp., the family Psilotaceae, the genus Psilotum is contained.
摘要翻译：本发明提供一种具有优异的皮肤美白活性的美白剂，并且在晒斑后的减轻和增白色素沉着，老化斑，雀斑，黄褐斑等具有优异的作用，以及抗氧化剂和抗老化剂，其具有具有优异的自由基清除能力，用于预防和控制由活性氧（自由基）引起的皮肤和皮肤疾病的老化，并具有高度的安全性。 [解决问题的手段]包含Psilotum spp。，Psilotaceae，Psilotum属的提取物。

2. 发明申请

US20120141400A1 EXTERNAL SKIN PREPARATION, WHITENER, ANTIOXIDANT AND ANTI-AGING AGENT 审中-公开
标题翻译：外用皮肤制剂，白蛋白，抗氧化剂和抗老化剂
公开(公告)号：US20120141400A1
公开(公告)日：2012-06-07
申请号：US13261178
申请日：2010-08-03
申请人： Rikako Suzuki , Kiyotaka Hasegawa , Kiyoshi Sato , Ken Kusakari , Tokiya Yokoi
发明人： Rikako Suzuki , Kiyotaka Hasegawa , Kiyoshi Sato , Ken Kusakari , Tokiya Yokoi
IPC分类号： A61K8/97 , A61Q19/08 , A61P17/18 , A61Q19/02
CPC分类号： A61K36/185 , A61K8/97 , A61K2800/522 , A61Q19/00 , A61Q19/02 , A61Q19/08
摘要： Provided are a whitener having superior whitening action and superior skin lightening and whitening effects against pigment deposition, age spots, freckles, liver spots and the like, and an antioxidant and anti-aging agent having superior free radical capturing abilities that prevent and/or inhibit skin aging and skin diseases caused by active oxygen (free radicals). The whitener, antioxidant and anti-aging agent contain an extract from Polyalthia longifolia.
摘要翻译：本发明提供一种具有优异的美白作用和对颜料沉积，老年斑，雀斑，肝斑等具有优异的皮肤增白和美白效果的美白剂，以及具有优异的自由基捕获能力的抗氧化剂和抗老化剂，其防止和/或抑制皮肤老化和皮肤疾病引起的活性氧（自由基）。增白剂，抗氧化剂和抗老化剂含有来自Polyalthia longifolia的提取物。

3. 发明申请

US20120122951A1 SKIN-WHITENING AGENT AND COSMETIC METHOD FOR WHITENING SKIN 审中-公开
标题翻译：用于白化皮肤的皮肤白化剂和化妆方法
公开(公告)号：US20120122951A1
公开(公告)日：2012-05-17
申请号：US13138787
申请日：2010-03-04
申请人： Rikako Suzuki , Yosuke Tojo , Chieko Mizumoto , Kiyotaka Hasegawa , Yutaka Ashida , Jun-ichi Hosoi , Kiyoshi Sato
发明人： Rikako Suzuki , Yosuke Tojo , Chieko Mizumoto , Kiyotaka Hasegawa , Yutaka Ashida , Jun-ichi Hosoi , Kiyoshi Sato
IPC分类号： A61K31/40 , A61Q19/02 , C07D207/16
CPC分类号： A61K31/401 , A23L33/175 , A23V2002/00 , A61K8/0212 , A61K8/0216 , A61K8/4913 , A61K2800/92 , A61Q19/02 , A23V2200/318
摘要： The development of a skin-whitening agent which has a lower molecular weight, can be synthesized through a fewer steps and can be produced at low cost has been demanded. Thus, it is provided by the present invention a skin-whitening agent including one or more compounds selected from the group consisting of 4-cis-hydroxyproline and its derivative and/or its salt, a skin-whitening composition for external formulation to the skin, a cosmetic composition and a pharmaceutical composition, each of which contains the skin-whitening agent of the invention, and a cosmetic method for whitening the skin, which includes a step of administering one or more compounds selected from the group consisting of 4-cis-hydroxyproline and its derivative and/or its salt. In the skin-whitening agent and the cosmetic method for whitening the skin of the invention, the 4-cis-hydroxyproline may be 4-cis-L-hydroxyproline and/or 4-cis-D-hydroxyproline.
摘要翻译：需要开发具有较低分子量的皮肤增白剂，可以通过较少的步骤合成并且可以以低成本生产。因此，本发明提供一种皮肤增白剂，其包含一种或多种选自4-顺式 - 羟基脯氨酸及其衍生物和/或其盐的化合物，用于皮肤外用制剂的皮肤增白组合物，化妆品组合物和药物组合物，其含有本发明的皮肤增白剂和美白化妆品的方法，其包括给予一种或多种选自4-顺式 - 羟脯氨酸及其衍生物和/或其盐。在本发明的皮肤美白剂和美白化妆品的美白方法中，4-顺式 - 羟基脯氨酸可以是4-顺式-L-羟基脯氨酸和/或4-顺式-D-羟基脯氨酸。

4. 发明申请

US20130109878A1 4-Alkylresorcinol Derivative And External Preparation For Skin Containing The Same 有权
标题翻译： 4-烷基间苯二酚衍生物及其外用制剂
公开(公告)号：US20130109878A1
公开(公告)日：2013-05-02
申请号：US13809696
申请日：2011-06-01
申请人： Hirotada Fukunishi , Rikako Suzuki , Kiyoshi Sato , Masaru Suetsugu
发明人： Hirotada Fukunishi , Rikako Suzuki , Kiyoshi Sato , Masaru Suetsugu
IPC分类号： C07F9/09
CPC分类号： C07F9/09 , A61K8/55 , A61K2800/782 , A61Q19/02 , C07F9/12
摘要： The present invention provides a compound that has a high whitening effect and is excellent in safety and stability and provides an external preparation for skin comprising the same. The compound of the present invention is a 4-alkylresorcinol derivative represented by formula (1) or a salt thereof: wherein R1 is a branched or cyclic alkyl group of 3 to 7 carbon atoms or a linear alkyl group of 2 to 5 carbon atoms; R2 and R3 are each independently a hydrogen atom or a group represented by —P(O)(OR4)(OR5), and at least one of R2 and R3 is a group represented by —P(O)(OR4)(OR5); and R4 and R5 are each independently a hydrogen atom or a linear or branched alkyl group of 2 to 5 carbon atoms.
摘要翻译：本发明提供了具有高白化效果并且安全性和稳定性优异的化合物，并且提供了包含其的皮肤外用剂。本发明的化合物是式（1）表示的4-烷基间苯二酚衍生物或其盐：其中，R 1为碳原子数3〜7的支链或环状烷基或碳原子数2〜5的直链烷基; R 2和R 3各自独立地为氢原子或由-P（O）（OR 4）（OR 5）表示的基团，R 2和R 3中的至少一个为-P（O）（OR 4）（OR 5） ; R 4和R 5各自独立地为氢原子或2〜5个碳原子的直链或支链烷基。

5. 发明授权

US08486919B2 4-alkylresorcinol derivative and external preparation for skin containing the same 有权
标题翻译： 4-烷基间苯二酚衍生物和含有其的皮肤外用剂
公开(公告)号：US08486919B2
公开(公告)日：2013-07-16
申请号：US13809696
申请日：2011-06-01
申请人： Hirotada Fukunishi , Rikako Suzuki , Kiyoshi Sato , Masaru Suetsugu
发明人： Hirotada Fukunishi , Rikako Suzuki , Kiyoshi Sato , Masaru Suetsugu
IPC分类号： A61K31/6615 , C07F9/12
CPC分类号： C07F9/09 , A61K8/55 , A61K2800/782 , A61Q19/02 , C07F9/12
摘要： The present invention provides a compound that has a high whitening effect and is excellent in safety and stability and provides an external preparation for skin comprising the same. The compound of the present invention is a 4-alkylresorcinol derivative represented by formula (1) or a salt thereof: wherein R1 is a branched or cyclic alkyl group of 3 to 7 carbon atoms or a linear alkyl group of 2 to 5 carbon atoms; R2 and R3 are each independently a hydrogen atom or a group represented by —P(O)(OR4)(OR5), and at least one of R2 and R3 is a group represented by —P(O)(OR4)(OR5); and R4 and R5 are each independently a hydrogen atom or a linear or branched alkyl group of 2 to 5 carbon atoms.
摘要翻译：本发明提供了具有高白化效果并且安全性和稳定性优异的化合物，并且提供了包含其的皮肤外用剂。本发明的化合物是式（1）表示的4-烷基间苯二酚衍生物或其盐：其中，R 1为碳原子数3〜7的支链或环状烷基或碳原子数2〜5的直链烷基; R 2和R 3各自独立地为氢原子或由-P（O）（OR 4）（OR 5）表示的基团，R 2和R 3中的至少一个为-P（O）（OR 4）（OR 5） ; R 4和R 5各自独立地为氢原子或2〜5个碳原子的直链或支链烷基。

6. 发明申请

US20090136540A1 Anti-aging composition and collagen production promoting composition 审中-公开
标题翻译：抗衰老组合物和胶原蛋白生成促进作用
公开(公告)号：US20090136540A1
公开(公告)日：2009-05-28
申请号：US12320088
申请日：2009-01-16
申请人： Keiko Takada , Rikako Suzuki , Miki Guentert , Shinji Inomata , Chika Hamada , Takayuki Sakiguchi
发明人： Keiko Takada , Rikako Suzuki , Miki Guentert , Shinji Inomata , Chika Hamada , Takayuki Sakiguchi
IPC分类号： A61K36/06
CPC分类号： A61K8/99 , A61Q19/08
摘要： There are provided an anti-aging composition, a collagen production promoting composition, a collagen gel contraction promoting composition, and an integrin production promoting composition for promoting integrin production in fibroblasts/epidermal cell, which have improved collagen production promotion effect and are effective for preventing or reducing wrinkle and/or sagging caused by aging. These anti-aging composition and promoting composition comprise, as an active ingredient, a hydrogen peroxide-treated yeast hydrolysate.
摘要翻译：提供抗老化组合物，胶原蛋白生成促进组合物，胶原凝胶收缩促进组合物和用于促进成纤维细胞/表皮细胞中整联蛋白产生的整联蛋白生产促进组合物，其具有改善的胶原蛋白生产促进作用并且有效预防或减少由老化引起的皱纹和/或松弛。这些抗衰老组合物和促进组合物包含作为活性成分的过氧化氢处理的酵母水解物。

7. 发明授权

US5504690A Automatic logic designing method and system 失效
标题翻译：自动逻辑设计方法和系统
公开(公告)号：US5504690A
公开(公告)日：1996-04-02
申请号：US108044
申请日：1993-08-16
申请人： Naohiro Kageyama , Toru Shonai , Rikako Suzuki , Takashi Okada , Kazuhiko Iijima , Hiroyuki Nakajima , Chihei Miura , Tsuguo Shimizu
发明人： Naohiro Kageyama , Toru Shonai , Rikako Suzuki , Takashi Okada , Kazuhiko Iijima , Hiroyuki Nakajima , Chihei Miura , Tsuguo Shimizu
IPC分类号： G06F17/50
CPC分类号： G06F17/5045
摘要： An automatic logic designing method and system in which a control table describing a condition and a behavior corresponding to the condition which express the specification of a computer is inputted and processed in a processor so that a logic circuit having no redundancy which can be easily seen by the designer is designed at a high speed. The control table is converted into the logic circuit whose function is expressed by a detailed Boolean expression. In an instance, selector logics are allocated in consideration of the polarity of the logic. A redundancy detection process or a redundancy logic elimination process is executed for the redundancy logics designated by a redundancy indicate file. A signal name which can be easily understood by the logic designer is formed. An implementing system includes an input control table file, a functional structure converting section of a conditional equation and a behavioral structure, a regular logic expanding processing section, and a redundancy logic elimination processing section, so that the logic circuit formed is outputted to a Boolean expression file.
摘要翻译：一种自动逻辑设计方法和系统，其中描述与表达计算机的规格的条件相对应的条件和行为的控制表在处理器中被输入和处理，使得不具有冗余的逻辑电路可以容易地被设计师是高速设计的。控制表转换为逻辑电路，其功能由详细的布尔表达式表示。在一种情况下，考虑到逻辑的极性来分配选择器逻辑。对由冗余指示文件指定的冗余逻辑执行冗余检测处理或冗余逻辑消除处理。可以形成由逻辑设计者容易理解的信号名称。实现系统包括输入控制表文件，条件方程式的功能结构转换部分和行为结构，规则逻辑扩展处理部分和冗余逻辑消除处理部分，使得形成的逻辑电路输出到布尔值表达文件。

8. 发明申请

US20070134265A1 Anti-aging composition and collagen production promoting composition 审中-公开
标题翻译：抗衰老组合物和胶原蛋白生成促进作用
公开(公告)号：US20070134265A1
公开(公告)日：2007-06-14
申请号：US10588780
申请日：2004-05-18
申请人： Keiko Takada , Rikako Suzuki , Miki Guentert , Shinji Inomata , Chika Hamada , Takayuki Sakiguchi
发明人： Keiko Takada , Rikako Suzuki , Miki Guentert , Shinji Inomata , Chika Hamada , Takayuki Sakiguchi
IPC分类号： A61K36/06 , A61K31/737
CPC分类号： A61K8/99 , A61Q19/08
摘要： There are provided an anti-aging composition, a collagen production promoting composition, a collagen gel contraction promoting composition, and an integrin production promoting composition for promoting integrin production in fibroblasts/epidermal cell, which have improved collagen production promotion effect and are effective for preventing or reducing wrinkle and/or sagging caused by aging. These anti-aging composition and promoting composition comprise, as an active ingredient, a hydrogen peroxide-treated yeast hydrolysate.
摘要翻译：提供抗老化组合物，胶原蛋白生成促进组合物，胶原凝胶收缩促进组合物和用于促进成纤维细胞/表皮细胞中整联蛋白产生的整联蛋白生产促进组合物，其具有改善的胶原蛋白生产促进作用并且有效预防或减少由老化引起的皱纹和/或松弛。这些抗衰老组合物和促进组合物包含作为活性成分的过氧化氢处理的酵母水解物。

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