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1. 发明授权

US06375618B1 Enhanced tissue-generated harmonic imaging using coded excitation 有权
标题翻译：使用编码激励增强组织生成的谐波成像
公开(公告)号：US06375618B1
公开(公告)日：2002-04-23
申请号：US09494465
申请日：2000-01-31
申请人： Richard Yung Chiao , Yasuhito Takeuchi , Anne Lindsay Hall , Kai Erik Thomenius
发明人： Richard Yung Chiao , Yasuhito Takeuchi , Anne Lindsay Hall , Kai Erik Thomenius
IPC分类号： A61B800
CPC分类号： G01S15/8979 , A61B8/06 , A61B8/13 , A61B8/481 , G01S7/52025 , G01S7/52038 , G01S15/8959 , G01S15/8961
摘要： In performing tissue-generated harmonic imaging using coded excitation, the transmit waveform for acquiring the N-th harmonic signal is biphase (1,−1) encoded using two code symbols of a code sequence, the portions (i.e., chips) of the transmit waveform encoded with the second code symbol each being phase-shifted by 180°/N relative to the chips encoded with the first code symbol. This is implemented by time shifting the portions (i.e., chips) of the transmit sequence which are encoded with the second code symbol by ½N fractional cycle at center frequency relative to the chips of the transmit sequence encoded with the first code symbol. During reception, the desired harmonic signal is isolated by a bandpass filter centered at twice the fundamental frequency and enhanced with decoding.
摘要翻译：在使用编码激励进行组织生成的谐波成像时，用于获取N次谐波信号的发送波形是使用码序列的两个码符号进行编码的双相（1，-1），发送的部分（即，码片）用第二代码符号编码的波形，每个相对于用第一代码符号编码的码片相移180°/ N。这是通过使用第二代码符号编码的发送序列的部分（即，芯片）以中心频率相对于以第一代码符号编码的发送序列的码片为中心的1/2分数周期来实现的。在接收期间，期望的谐波信号由以基频两倍为中心的带通滤波器隔离，并通过解码增强。

2. 发明授权

US6074348A Method and apparatus for enhanced flow imaging in B-mode ultrasound 失效
标题翻译：用于B型超声波增强流动成像的方法和装置
公开(公告)号：US6074348A
公开(公告)日：2000-06-13
申请号：US65212
申请日：1998-04-23
申请人： Richard Yung Chiao , Anne Lindsay Hall , Kai Erik Thomenius , Michael Joseph Washburn , Kenneth Wayne Rigby
发明人： Richard Yung Chiao , Anne Lindsay Hall , Kai Erik Thomenius , Michael Joseph Washburn , Kenneth Wayne Rigby
IPC分类号： H04N7/18 , A61B8/06 , G01S7/52 , G01S15/89 , G06T1/00 , A61B8/00
CPC分类号： G01S15/8988 , G01S15/8993 , G01S7/52039 , G01S7/52046 , G01S7/5206 , G01S15/8981 , G01S7/52038
摘要： A method and apparatus for ultrasonically imaging flow directly in B mode employs a sequence of pulses transmitted to a transmit focal position, with the backscattered signals from this sequence being filtered to remove echoes from stationary or slow-moving reflectors along the transmit path. The resulting flow signals are superimposed on a conventional B-mode vector and displayed. A B-mode flow image is formed by repeating this procedure for multiple transmit focal positions across the region of interest. The filtering is performed in slow time (along transmit firings) using a high-pass "wall" filter (e.g., an FIR filter) with harmonic image feed-through and optionally B-mode (fundamental) feed-through. The resulting B-mode flow image has low clutter from stationary or slow-moving tissue or vessel walls, high resolution, high frame rate and flow sensitivity in all directions.
摘要翻译：用于以B模式直接成像流体的方法和装置采用传输到发射焦点位置的脉冲序列，其中来自该序列的反向散射信号被滤波，以沿着发射路径移除来自静止或慢速移动的反射器的回波。所得到的流量信号叠加在传统的B模式向量上并显示。通过对感兴趣区域的多个发射焦点位置重复该过程来形成B模式流图像。使用具有谐波图像馈通和可选的B模式（基本）馈通的高通“壁”滤波器（例如FIR滤波器），在缓慢的时间（沿着发射发射）进行滤波。所得到的B模式流动图像具有来自静止或缓慢移动的组织或血管壁的低杂波，高分辨率，高帧率和在所有方向上的流动敏感性。

3. 发明授权

US5980459A Ultrasound imaging using coded excitation on transmit and selective filtering of fundamental and (sub)harmonic signals on receive 失效
标题翻译：超声成像使用编码激励对接收上的基波和（次）谐波信号的发射和选择滤波
公开(公告)号：US5980459A
公开(公告)日：1999-11-09
申请号：US52675
申请日：1998-03-31
申请人： Richard Yung Chiao , Ann Lindsay Hall , Kai Erik Thomenius
发明人： Richard Yung Chiao , Ann Lindsay Hall , Kai Erik Thomenius
IPC分类号： A61B8/00 , A61B8/06 , A61B8/08 , G01P5/00 , G01P5/24 , G01S7/52 , G01S15/89
CPC分类号： A61B8/481 , A61B8/06 , A61B8/13 , G01P5/001 , G01P5/244 , G01S7/52038 , G01S7/52039 , G01S15/8981
摘要： A method and an apparatus for selectively performing contrast harmonic imaging, tissue harmonic imaging and B-mode flow imaging with an ultrasound imaging system utilizes phase-coded excitation on transmit and selective firing-to-firing, i.e., "slow-time", filtering on receive. "Slow-time" filtering in combination with transmit phases which change over the set of transmit firings results in different effective "slow-time" filters corresponding to the different harmonic modes within the reflected signal. The transmit phases and the "slow-time" filter weightings are designed to selectively enhance the desired modes while substantially suppressing other modes.
摘要翻译：利用超声成像系统选择性地执行对比度谐波成像，组织谐波成像和B模式流动成像的方法和装置在发射和选择性点火到点火（即“慢时间”）上利用相位编码激励接收。结合传输阶段的“慢时间”滤波结合传输发射集合导致与反射信号内的不同谐波模式对应的不同的有效“慢时间”滤波器。发射相位和“慢时间”滤波器加权被设计成选择性地增强期望的模式，同时基本上抑制其它模式。

4. 发明授权

US06558328B2 Method and apparatus using coded excitation in ultrasonic perfusion imaging 有权
标题翻译：超声灌注成像中使用编码激励的方法和装置
公开(公告)号：US06558328B2
公开(公告)日：2003-05-06
申请号：US09871881
申请日：2001-06-04
申请人： Richard Yung Chiao , Jonathan Matthews Rubin , Kai Erik Thomenius
发明人： Richard Yung Chiao , Jonathan Matthews Rubin , Kai Erik Thomenius
IPC分类号： A61B800
CPC分类号： G01S15/8979 , A61B8/06 , A61B8/13 , A61B8/481 , G01S7/52025 , G01S7/52038 , G01S15/8959 , G01S15/8961
摘要： A method and an apparatus for perfusion imaging using coded excitation. Bursting pulses are scanned over the region of interest in one or more frames followed by scanning one or more encoded imaging pulses in each subsequent frame. The bursting pulse is intended to break contrast micro-bubbles within a transmit focal zone and therefore should have high mechanical index and low frequency. The basic concept is to use a very low-amplitude encoded pulse train to image the contrast agents. The low amplitude prevents the contrast bubbles in the transmit focal zone from being destroyed while imaging, and the coded excitation provides the necessary signal-to-noise ratio. The imaging pulses are transmitted during refilling of the transmit focal zone with contrast agent subsequent to transmission of the bursting pulse into the transmit focal zone. On receive, the receive vectors are decoded to form a compressed pulse.
摘要翻译：一种使用编码激励的灌注成像的方法和装置。在一个或多个帧中的感兴趣区域上扫描突发脉冲，随后在每个后续帧中扫描一个或多个编码的成像脉冲。爆裂脉冲旨在打破发射聚焦区域内的对比度微气泡，因此应具有高机械指数和低频率。基本概念是使用非常低幅度的编码脉冲串对造影剂进行成像。低幅度防止发射聚焦区域中的对比气泡在成像时被破坏，并且编码的激发提供必要的信噪比。在将突发脉冲发送到发射聚焦区之后，用造影剂重新填充发射聚焦区域期间发射成像脉冲。在接收时，接收矢量被解码以形成压缩脉冲。

5. 发明授权

US06478741B2 Transmission of optimized pulse waveforms for ultrasonic subharmonic imaging 失效
标题翻译：超声次谐波成像优化脉冲波形传输
公开(公告)号：US06478741B2
公开(公告)日：2002-11-12
申请号：US09810048
申请日：2001-03-19
申请人： Richard Yung Chiao , Anne Lindsay Hall
发明人： Richard Yung Chiao , Anne Lindsay Hall
IPC分类号： A61B800
CPC分类号： G01S15/8959 , G01S7/52038 , G01S15/8915
摘要： An optimized pulse waveform is used to excite contrast microbubbles such that the subharmonic signal may be easily isolated for imaging. By reducing the contribution of transmitted fundamental frequency f0 within the subharmonic band, the subharmonic imaging quality is improved. This is accomplished by transmitting an optimized pulse waveform and then filtering the received signal to isolate the subharmonic signal for imaging. The optimized pulse waveform has low spectral energy within a band of frequencies centered at f0/2 and high spectral energy within another band of frequencies centered at f0, where both bands are within the transducer passband. The contrast-generated subharmonic signal is extracted by a receive filter centered at f0/2.
摘要翻译：优化的脉冲波形用于激发对比微泡，使得次谐波信号可以容易地隔离成像。通过减小次谐波带内发射的基频f0的贡献，提高了次谐波成像质量。这是通过发送优化的脉冲波形然后对接收到的信号进行滤波来隔离成分的次谐波信号来实现的。优化的脉冲波形在以f0 / 2为中心的频率带内具有低频谱能量，以及以f0为中心的另一频率频带内的高频谱能量，其中两个频带均在换能器通带内。对比度产生的次谐波信号由以f0 / 2为中心的接收滤波器提取。

6. 发明授权

US06210332B1 Method and apparatus for flow imaging using coded excitation 有权
标题翻译：使用编码激励的流量成像方法和装置
公开(公告)号：US06210332B1
公开(公告)日：2001-04-03
申请号：US09437605
申请日：1999-11-10
申请人： Richard Yung Chiao , David John Muzilla , Anne Lindsay Hall , Cynthia Andrews Owen
发明人： Richard Yung Chiao , David John Muzilla , Anne Lindsay Hall , Cynthia Andrews Owen
IPC分类号： A61B800
CPC分类号： G01S7/52046 , G01S7/52023 , G01S7/52038 , G01S7/52039 , G01S7/5206 , G01S15/8918 , G01S15/8954 , G01S15/8959 , G01S15/8961 , G01S15/8979 , G01S15/8981 , G01S15/8988 , G01S15/8993 , Y10S128/916
摘要： In performing flow imaging using coded excitation and wall filtering, a coded sequence of broadband pulses (centered at a fundamental frequency) is transmitted multiple times to a particular transmit focal position, each coded sequence constituting one firing. On receive, the receive signals acquired for each firing are supplied to a finite impulse response filter which both compresses and bandpass filters the receive pulses, e.g., to isolate a compressed pulse centered at the fundamental frequency. The compressed and isolated signals are then high pass filtered across firings using a wall filter. The wall-filtered signals are used to image blood flow and contrast agents.
摘要翻译：在使用编码激励和壁滤波执行流动成像的过程中，宽带脉冲编码序列（以基频为中心）被多次发送到特定发射焦点位置，每个编码序列构成一个发射。在接收时，为每个发射获取的接收信号被提供给有限脉冲响应滤波器，它们对接收脉冲进行压缩和带通滤波，例如隔离以基频为中心的压缩脉冲。压缩和隔离的信号然后使用墙壁过滤器通过发射进行高通滤波。壁过滤的信号用于对血流和造影剂进行成像。

7. 发明授权

US5984869A Method and apparatus for ultrasonic beamforming using golay-coded excitation 失效
公开(公告)号：US5984869A
公开(公告)日：1999-11-16
申请号：US63109
申请日：1998-04-20
申请人： Richard Yung Chiao , Lewis Jones Thomas, III
发明人： Richard Yung Chiao , Lewis Jones Thomas, III
IPC分类号： G01S7/52 , G01S15/89 , A61B8/00
CPC分类号： G01S15/8961 , G01S15/8927 , G01S15/8959 , G01S7/52046
摘要： A method and apparatus for improving the SNR in medical ultrasound imaging utilize Golay-coded excitation of the transducer array. A Golay pair is a pair of binary (+1,-1) sequences with the property that the sum of the autocorrelations of the two sequences is a Kronecker delta function. This translates into two important advantages over codes in general: (1) Golay codes have no range sidelobes, and (2) Golay codes can be transmitted using only a bipolar pulser versus a more expensive digital-to-analog converter. Degradation of the Golay code is avoided by employing multiple focal zones, where the Golay code is used only in the deepest focal zones in order to minimize dynamic focusing effects, and by employing two consecutive transmits on each beam to minimize tissue motion between the two code sequences.

8. 发明授权

US07338446B2 Method and apparatus for controlling power in an ultrasound system 有权
标题翻译：用于在超声系统中控制功率的方法和装置
公开(公告)号：US07338446B2
公开(公告)日：2008-03-04
申请号：US10838400
申请日：2004-05-04
申请人： Michael Charles MacDonald , Richard Yung Chiao , Yadong Li , Lihong Pan
发明人： Michael Charles MacDonald , Richard Yung Chiao , Yadong Li , Lihong Pan
IPC分类号： A61B8/00
CPC分类号： G01S7/52096 , G01S15/899
摘要： Methods and systems for controlling an ultrasound system are provided. The method includes receiving scanning information from an ultrasound system, with the scanning information including at least one of image information and spectral information. The method further includes controlling power to a transducer of the ultrasound system based on the scanning information.
摘要翻译：提供了用于控制超声系统的方法和系统。该方法包括从超声系统接收扫描信息，扫描信息包括图像信息和光谱信息中的至少一个。该方法还包括基于扫描信息来控制超声系统的换能器的功率。

9. 发明授权

US06186949B1 Method and apparatus for three-dimensional flow imaging using coded excitation 失效
标题翻译：使用编码激励的三维流动成像的方法和装置
公开(公告)号：US06186949B1
公开(公告)日：2001-02-13
申请号：US09411207
申请日：1999-10-04
申请人： William Thomas Hatfield , Richard Yung Chiao
发明人： William Thomas Hatfield , Richard Yung Chiao
IPC分类号： A61B800
CPC分类号： G01S15/8988 , G01S7/52038 , G01S7/52039 , G01S7/52046 , G01S7/5206 , G01S15/8959 , G01S15/8981 , G01S15/8993 , Y10S128/916
摘要： In performing three-dimensional flow imaging using coded excitation and wall filtering, a coded sequence of broadband pulses (centered at a fundamental frequency) is transmitted multiple times to a particular transmit focal position. On receive, the receive signals acquired for each firing are compressed and bandpass filtered to isolate a compressed pulse centered at the fundamental frequency. The compressed and isolated signals are then wall filtered to extract the flow imaging data. This process is repeated for a multiplicity of transmit focal positions in each of a multiplicity of scanning planes to acquire a volume of flow imaging data. Volume rendered images are then produced which allow the user to view the data volume from any angle. In addition, the data volume may be reformatted to produce two-dimensional images of arbitrary cut planes through the data volume.
摘要翻译：在使用编码激励和壁滤波进行三维流动成像的过程中，宽带脉冲编码序列（以基频为中心）被多次发送到特定的发射焦点位置。在接收时，为每次点火采集的接收信号被压缩并进行带通滤波以隔离以基频为中心的压缩脉冲。然后将压缩和隔离的信号进行壁过滤以提取流动成像数据。对于多个扫描平面中的每一个中的多个发射焦点位置重复该过程以获取流量成像数据的体积。然后产生体绘制的图像，其允许用户从任何角度观看数据量。另外，可以重新格式化数据量以通过数据量产生任意切割平面的二维图像。

10. 发明授权

US5882309A Multi-row ultrasonic transducer array with uniform elevator beamwidth 失效
标题翻译：具有均匀电梯波束宽度的多列超声波换能器阵列
公开(公告)号：US5882309A
公开(公告)日：1999-03-16
申请号：US852810
申请日：1997-05-07
申请人： Richard Yung Chiao , Douglas Glenn Wildes
发明人： Richard Yung Chiao , Douglas Glenn Wildes
IPC分类号： G01N29/24 , A61B8/00 , G01S7/52 , G01S15/89 , G06T1/00 , H04R1/00 , H04R1/34 , H04R17/00
CPC分类号： G01S15/8925 , G01S7/52046
摘要： A multi-row ultrasound transducer array having a central row of transducer elements and a pair of outermost rows of transducer elements on opposing sides of the central row. The corresponding elements of the outermost rows are connected in parallel to a respective signal lead. The area of each element in the central row is less than the combined area of each pair of elements of the outermost rows. The greater total area of the combined elements of the outermost rows as compared to the area of each element of the central row provides improved elevation performance (thinner and more uniform image slice, greater contrast resolution), especially in the very near field, as compared to conventional transducers. The array may further include one or more pairs of rows of elements intermediate the central row and the respective outermost rows. The corresponding elements of the intermediate rows are connected in parallel to respective signal leads. The combined area of each pair of elements of the intermediate rows is less than the combined area of each pair of elements of the outermost rows, but greater than the area of a central row element.
摘要翻译：一种多列超声换能器阵列，其具有中心排的换能器元件和在中心排的相对侧上的一对最外面的换能器元件。最外面的行的相应元件与相应的信号引线并联连接。中央行中的每个元素的面积小于最外面行的每对元素的组合面积。与中央行的每个元件的面积相比，最外面行的组合元件的总面积更大，提供了改进的高程性能（更薄和更均匀的图像切片，更大的对比度分辨率），特别是在非常近的场域传统传感器。阵列还可以包括在中心行和相应的最外行之间的一对或多对元件行。中间行的相应元件并联连接到相应的信号引线。中间行的每对元素的组合面积小于最外面行的每对元素的组合面积，但是大于中央行元素的面积。

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