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1. 发明申请

US20060045822A1 Plasma polymerization for encapsulating particles 审中-公开
公开(公告)号：US20060045822A1
公开(公告)日：2006-03-02
申请号：US10931480
申请日：2004-09-01
申请人： Richard Timmons , Ceren Susut
发明人： Richard Timmons , Ceren Susut
IPC分类号： B01J19/00
CPC分类号： B05D1/62 , B01J19/088 , B01J2219/0809 , B01J2219/0832 , B01J2219/0841 , B01J2219/0886 , C08F2/00
摘要： The present invention includes systems, methods and compositions for the encapsulation of particles. In one form, the system comprises one or more particles, a rotatable reaction chamber in a plasma enhanced chemical reactor to accept one or more particles, and at least one carbonaceous compound to be used in the rotatable reaction chamber, wherein the carbonaceous compound is polymerized onto a surface of one or more particles forming a polymer film encapsulating one or more particles. Using systems, methods, and compositions of the present invention, any particle encapsulated with a degradable or nondegradable polymer film may be introduced and/or released into an environment. The polymer film as well as introduction of encapsulated particles and release therefrom into an environment are controlled by the present invention.

2. 发明授权

US09120125B2 Plasma polymerization for encapsulating particles 有权
标题翻译：用于封装颗粒的等离子体聚合
公开(公告)号：US09120125B2
公开(公告)日：2015-09-01
申请号：US14068575
申请日：2013-10-31
申请人： Richard B. Timmons , Ceren Susut
发明人： Richard B. Timmons , Ceren Susut
IPC分类号： G01N33/15 , B05D1/00 , B01J19/08 , C08F2/00
CPC分类号： B05D1/62 , B01J19/088 , B01J2219/0809 , B01J2219/0832 , B01J2219/0841 , B01J2219/0886 , C08F2/00
摘要： The present invention includes systems, methods and compositions for the encapsulation of particles. In one form, the system comprises one or more particles, a rotatable reaction chamber in a plasma enhanced chemical reactor to accept one or more particles, and at least one carbonaceous compound to be used in the rotatable reaction chamber, wherein the carbonaceous compound is polymerized onto a surface of one or more particles forming a polymer film encapsulating one or more particles. Using systems, methods, and compositions of the present invention, any particle encapsulated with a degradable or nondegradable polymer film may be introduced and/or released into an environment. The polymer film as well as introduction of encapsulated particles and release therefrom into an environment are controlled by the present invention.
摘要翻译：本发明包括用于颗粒包封的系统，方法和组合物。在一种形式中，该系统包括一个或多个颗粒，等离子体增强化学反应器中可接受一个或多个颗粒的可旋转反应室，以及用于可旋转反应室中的至少一种碳质化合物，其中碳质化合物聚合在形成包封一个或多个颗粒的聚合物膜的一个或多个颗粒的表面上。使用本发明的系统，方法和组合物，用可降解或不可降解的聚合物膜包封的任何颗粒可以被引入和/或释放到环境中。聚合物膜以及包封颗粒的引入并从其释放到环境中是由本发明控制的。

3. 发明申请

US20100297248A1 ENCAPSULATED PARTICLES FOR AMORPHOUS STABILITY ENHANCEMENT 审中-公开
标题翻译：用于非晶稳定性增强的包封颗粒
公开(公告)号：US20100297248A1
公开(公告)日：2010-11-25
申请号：US12785162
申请日：2010-05-21
申请人： Richard B. Timmons , Ceren Susut , Donald E. Owens, III , J. Brian Windsor , Rachel Kennedy Khorzad
发明人： Richard B. Timmons , Ceren Susut , Donald E. Owens, III , J. Brian Windsor , Rachel Kennedy Khorzad
IPC分类号： A61K9/58 , A61K31/4196 , A61K31/19
CPC分类号： B01J19/088 , A61K9/5015 , A61K9/5026 , B01J2219/0809 , B01J2219/0832 , B01J2219/0841 , B01J2219/0886 , C08F2/00
摘要： The present invention provides compositions and methods of making and encapsulating one or more active agents in a chemical vapor deposition layer to enhance the stability.
摘要翻译：本发明提供了在化学气相沉积层中制备和包封一种或多种活性剂以提高稳定性的组合物和方法。

4. 发明申请

US20140053780A1 Plasma Polymerization for Encapsulating Particles 有权
标题翻译：用于封装颗粒的等离子体聚合
公开(公告)号：US20140053780A1
公开(公告)日：2014-02-27
申请号：US14068575
申请日：2013-10-31
申请人： Richard B. Timmons , Ceren Susut
发明人： Richard B. Timmons , Ceren Susut
IPC分类号： B05D1/00
CPC分类号： B05D1/62 , B01J19/088 , B01J2219/0809 , B01J2219/0832 , B01J2219/0841 , B01J2219/0886 , C08F2/00
摘要： The present invention includes systems, methods and compositions for the encapsulation of particles. In one form, the system comprises one or more particles, a rotatable reaction chamber in a plasma enhanced chemical reactor to accept one or more particles, and at least one carbonaceous compound to be used in the rotatable reaction chamber, wherein the carbonaceous compound is polymerized onto a surface of one or more particles forming a polymer film encapsulating one or more particles. Using systems, methods, and compositions of the present invention, any particle encapsulated with a degradable or nondegradable polymer film may be introduced and/or released into an environment. The polymer film as well as introduction of encapsulated particles and release therefrom into an environment are controlled by the present invention.
摘要翻译：本发明包括用于颗粒包封的系统，方法和组合物。在一种形式中，该系统包括一个或多个颗粒，等离子体增强化学反应器中可接受一个或多个颗粒的可旋转反应室，以及用于可旋转反应室中的至少一种碳质化合物，其中碳质化合物聚合在形成包封一个或多个颗粒的聚合物膜的一个或多个颗粒的表面上。使用本发明的系统，方法和组合物，用可降解或不可降解的聚合物膜包封的任何颗粒可以被引入和/或释放到环境中。聚合物膜以及包封颗粒的引入并从其释放到环境中是由本发明控制的。

5. 发明申请

US20100297251A1 ENCAPSULATED PARTICLES FOR ENTERIC RELEASE 审中-公开
标题翻译：用于肠内释放的包封颗粒
公开(公告)号：US20100297251A1
公开(公告)日：2010-11-25
申请号：US12785271
申请日：2010-05-21
申请人： Richard B. Timmons , Ceren Susut , Donald E. Owens, III , J. Brian Windsor , Rachel Kennedy Khorzad
发明人： Richard B. Timmons , Ceren Susut , Donald E. Owens, III , J. Brian Windsor , Rachel Kennedy Khorzad
IPC分类号： A61K9/58 , A61K31/4196 , A61K31/343 , A61K31/12 , A61K38/13 , A61K31/56 , A61K31/19 , A61K31/55 , A61K31/52
CPC分类号： B01J19/088 , A61K9/5015 , A61K9/5026 , A61K9/5089 , B01J2219/0809 , B01J2219/0832 , B01J2219/0841 , B01J2219/0886 , C08F2/00 , G01N2013/006
摘要： The present invention provides a system for delivery of an enteric coated active agent generally resistant to disintegration in an neutral environment having one or more active agents encapsulated by a polymer coating formed by chemical vapor deposition of one or more monomers on the one or more active agents to form a chemical vapor deposition polymer coating that controls the release of the one or more active agents in the gastrointestinal tract.
摘要翻译：本发明提供了一种用于递送肠溶衣的活性剂的系统，其通常在中性环境中具有抗崩解的作用，所述中性环境具有一种或多种通过一种或多种活性剂的化学气相沉积形成的聚合物涂层包裹的活性剂以形成控制一种或多种活性剂在胃肠道中的释放的化学气相沉积聚合物涂层。

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