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1. 发明授权

US5583666A Method for cross-device color calibration and enhancement using explicit constraints 失效
标题翻译：使用显式约束的交叉设备颜色校准和增强的方法
公开(公告)号：US5583666A
公开(公告)日：1996-12-10
申请号：US390157
申请日：1995-02-16
申请人： Richard N. Ellson , Kevin E. Spaulding , Andrew H. Mutz , Ron Gershon
发明人： Richard N. Ellson , Kevin E. Spaulding , Andrew H. Mutz , Ron Gershon
IPC分类号： G06T1/00 , H04N1/46 , H04N1/60 , H04N1/62 , G02B7/00 , G02B5/12 , G09G5/04 , H04N9/64
CPC分类号： H04N1/62 , H04N1/6058
摘要： This invention provides a method for transforming an input color space to an output color space where each of a plurality of specified colors and/or color regions are constrained to be transformed by any one of a plurality of explicitly specified color calibration or color enhancement strategies. The method involves a two step process: 1) constraints are applied to some subset of the points in the input color space explicitly specifying the transform into the output color space; 2) the reminder of the points are then transformed by a mapping strategy which preserves color continuity. The mapping strategy used in the preferred embodiment is based on a computer graphics geometric morphing technique. In the preferred embodiment, multi-dimensional look-up tables are used to implement the color transformation.
摘要翻译：本发明提供了一种用于将输入颜色空间转换为输出颜色空间的方法，其中多个指定颜色和/或颜色区域中的每一个被约束以通过多个明确指定的颜色校准或颜色增强策略中的任何一个进行变换。该方法涉及两步过程：1）将约束应用于输入颜色空间中的某些点的子集，明确地将变换指定为输出颜色空间; 2）然后通过保持颜色连续性的映射策略来转换点的提醒。在优选实施例中使用的映射策略基于计算机图形几何变形技术。在优选实施例中，使用多维查找表来实现颜色变换。

2. 发明授权

US5539540A Method and associated apparatus for transforming input color values in an input color space to output color values in an output color space 失效
标题翻译：用于变换输入颜色空间中的输入颜色值以输出输出颜色空间中的颜色值的方法和相关联的装置
公开(公告)号：US5539540A
公开(公告)日：1996-07-23
申请号：US305861
申请日：1994-09-13
申请人： Kevin E. Spaulding , Ron Gershon , James R. Sullivan , Richard N. Ellson
发明人： Kevin E. Spaulding , Ron Gershon , James R. Sullivan , Richard N. Ellson
IPC分类号： G03F3/08 , G06T1/00 , H04N1/46 , H04N1/60
CPC分类号： H04N1/6058
摘要： This invention provides a method for mapping an input color space to an output color space in such a way that the color reproduction characteristics of the saturated colors can be adjusted in a custom manner, while maintaining the desired tone reproduction on the neutral axis. This is accomplished by defining independently a tone transformation and a transformation for a plurality of highly saturated colors. A transformation is formed for the remaining color values having the specified transforms for the neutral and saturated colors as boundary values. In the preferred embodiment multi-dimensional look-up tables are used to implement the transform.
摘要翻译：本发明提供了一种用于将输入颜色空间映射到输出颜色空间的方法，使得可以以定制的方式调整饱和色的颜色再现特性，同时保持中性轴上所需的色调再现。这通过独立地定义多个高度饱和的颜色的色调变换和变换来实现。形成具有用于中性和饱和颜色的指定变换的剩余颜色值作为边界值的变换。在优选实施例中，使用多维查找表来实现变换。

3. 发明授权

US06269184B1 Method and apparatus for interactive color transformation of color values between color spaces 失效
标题翻译：彩色空间之间颜色值交互式颜色转换的方法和装置
公开(公告)号：US06269184B1
公开(公告)日：2001-07-31
申请号：US08866469
申请日：1997-05-30
申请人： Kevin Edward Spaulding , Ron Gershon , Richard N. Ellson , James R. Sullivan
发明人： Kevin Edward Spaulding , Ron Gershon , Richard N. Ellson , James R. Sullivan
IPC分类号： G06K900
CPC分类号： H04N1/622
摘要： A method and apparatus for mapping a first color space into a second color space which allows a user to specify or constrain the mapping for a subset of the points within the first color space and determine the remaining unconstrained points according to a preexisting or default mapping.
摘要翻译：一种用于将第一颜色空间映射到第二颜色空间的方法和装置，其允许用户指定或约束第一颜色空间内的点的子集的映射，并且根据预先存在的或默认的映射来确定剩余的非约束点。

4. 发明申请

US20110277425A1 METHOD FOR STORING FLUID WITH CLOSURE INCLUDING MEMBERS WITH CHANGEABLE RELATIVE POSITIONS AND DEVICE THEREOF 有权
标题翻译：用于具有可变相关位置的包含成员的关闭的流体存储方法及其装置
公开(公告)号：US20110277425A1
公开(公告)日：2011-11-17
申请号：US13105790
申请日：2011-05-11
申请人： Richard N. Ellson
发明人： Richard N. Ellson
IPC分类号： B65B7/28
CPC分类号： C12M23/34 , B01L3/508 , B01L3/50853 , B01L2200/0689 , B01L2300/041 , B01L2300/0809 , B01L2300/0829 , C12M23/10 , C12M23/12 , C12M23/26 , C12M23/38
摘要： In a preferred embodiment of the invention, a closure for a container comprises at least two closure members. The relative position of the closure members with respect to each other is altered upon mating of the closure and container. The alteration of the relative position of the closure members may result in one or more of the members approaching the container more closely. The alteration may result in one or more of the members pressing against the container. The pressing may take place in such a way that exit paths for vapor from fluid in the container would require passage through the pressed surfaces.
摘要翻译：在本发明的优选实施例中，用于容器的封闭件包括至少两个闭合构件。封闭件相对于彼此的相对位置在封盖和容器配合时被改变。关闭构件的相对位置的改变可能导致一个或多个构件更接近容器。改变可能导致一个或多个构件压靠容器。按压可以以这样一种方式进行：用于来自容器中的流体的蒸气的出口路径将需要通过压制表面。

5. 发明授权

US07901039B2 Peptide arrays and methods of preparation 有权
标题翻译：肽阵列和制备方法
公开(公告)号：US07901039B2
公开(公告)日：2011-03-08
申请号：US11487062
申请日：2006-07-13
申请人： Mitchell W. Mutz , Richard N. Ellson
发明人： Mitchell W. Mutz , Richard N. Ellson
IPC分类号： B41J2/135 , C07K2/00
CPC分类号： B41J2/14008 , B01J19/0046 , B01J2219/00378 , B01J2219/00497 , B01J2219/00527 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00659 , B01J2219/00722 , B01J2219/00725 , B05B17/0615 , C40B40/06 , C40B40/10 , C40B60/14
摘要： The present invention relates to arrays of peptidic molecules and the preparation of peptide arrays using focused acoustic energy. The arrays are prepared by acoustically ejecting peptide-containing fluid droplets from individual reservoirs towards designated sites on a substrate for attachment thereto.
摘要翻译：本发明涉及肽分子的阵列和使用聚焦声能的肽阵列的制备。阵列通过将含有肽的流体液滴从各个储存器喷射到衬底上用于附着于其上的指定位点来制备。

6. 发明授权

US07900505B2 Acoustic assessment of fluids in a plurality of reservoirs 有权
标题翻译：对多个储层中流体的声学评估
公开(公告)号：US07900505B2
公开(公告)日：2011-03-08
申请号：US11329817
申请日：2006-01-10
申请人： Mitchell W. Mutz , Richard N. Ellson , James K. Foote
发明人： Mitchell W. Mutz , Richard N. Ellson , James K. Foote
IPC分类号： G01N29/00
CPC分类号： G01N29/028 , G01N11/10 , G01N29/032 , G01N29/222 , G01N2291/02416 , G01N2291/048 , G01N2291/102
摘要： The invention provides devices and methods for acoustically assessing the contents in a plurality of reservoirs. Each reservoir has a portion adapted to contain a fluid, and an acoustic radiation generator is positioned in acoustic coupling relationship to each of the reservoirs. Acoustic radiation generated by the acoustic radiation generator is transmitted through at least the portion of each reservoir to an analyzer. The analyzer is capable of analyzing a characteristic of the transmitted acoustic radiation and optionally correlating the characteristic to a property of the reservoirs' contents. The invention is particularly suited for assessing the contents of a plurality of reservoirs to allow for accuracy and control over the dispensing of fluids therefrom.
摘要翻译：本发明提供用于声学评估多个储存器中的内容物的装置和方法。每个储存器具有适于容纳流体的部分，并且声辐射发生器被定位成与每个储存器的声耦合关系。由声辐射发生器产生的声辐射通过至少每个储存器的部分传输到分析器。分析仪能够分析所发射的声辐射的特性，并且可选地将特征与储层内容物性相关联。本发明特别适用于评估多个储存器的内容物，以便准确地控制流体的分配。

7. 发明授权

US06869551B2 Precipitation of solid particles from droplets formed using focused acoustic energy 有权
标题翻译：使用聚焦声能沉淀形成的液滴中固体颗粒的沉淀
公开(公告)号：US06869551B2
公开(公告)日：2005-03-22
申请号：US10244128
申请日：2002-09-13
申请人： David Soong-Hua Lee , Richard N. Ellson , Theodore J. Williams
发明人： David Soong-Hua Lee , Richard N. Ellson , Theodore J. Williams
IPC分类号： A61J3/06 , A61K9/12 , A61K9/16 , A61K9/72 , B01J2/00 , B01J2/02 , B01J2/04 , B01J2/06 , B01J19/10 , B05B17/04 , B29B9/00
CPC分类号： A61K9/1688 , A61K9/122 , B01J2/02 , B01J2/04
摘要： Methods and devices are disclosed that use focused acoustic energy to generate solid particles containing at least one compound of interest. Focused acoustic radiation serves to eject droplets containing a compound of interest dissolved in a solvent. The droplets are subjected to a condition that allows for the compound of interest to precipitate out of solution, thereby generating solid particles. The particles are typically of controlled size, composition, and/or structure. Often, particles of substantially identical size are generated.
摘要翻译：公开了使用聚焦声能产生含有至少一种目的化合物的固体颗粒的方法和装置。聚焦的声辐射用于喷射含有溶解在溶剂中的目的化合物的液滴。使液滴经受允许感兴趣的化合物沉淀出溶液的条件，从而产生固体颗粒。颗粒通常具有受控的尺寸，组成和/或结构。通常，产生基本相同尺寸的颗粒。

8. 发明授权

US06806051B2 Arrays of partially nonhybridizing oligonucleotides and preparation thereof using focused acoustic energy 有权
标题翻译：部分非杂交寡核苷酸的阵列及其使用聚焦声能的制备
公开(公告)号：US06806051B2
公开(公告)日：2004-10-19
申请号：US09962731
申请日：2001-09-24
申请人： Richard N. Ellson
发明人： Richard N. Ellson
IPC分类号： C12Q168
CPC分类号： C07H21/00 , B01J19/0046 , B01J2219/00351 , B01J2219/0036 , B01J2219/00497 , B01J2219/00527 , B01J2219/00529 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00641 , B01J2219/00659 , B01J2219/00722 , C07B2200/11 , C40B40/06 , C40B60/14
摘要： Partially nonhybridizing oligonucleotides are provided that contain two or more hybridizing segments, with any two hybridizing segments separated by a nonhybridizing spacer segment, i.e., a nucleotidic or nonnucleotidic segment that has little or no likelihood of binding to an oligonucleotide sequence found in nature. Oligonucleotide arrays are also provided in which at least one of the oligonucleotides of the array is a partially nonhybridizing oligonucleotide. The partially nonhybridizing oligonucleotides serve as multifunctional probes wherein each hybridizing segment of a single partially nonhybridizing oligonucleotide serves as an individual probe. Also provided are methods for preparing and using the partially nonhybridizing oligonucleotides and arrays formed therewith. A particularly preferred method of array fabrication involves the use of focused acoustic energy.
摘要翻译：提供了部分非杂交寡核苷酸，其含有两个或更多个杂交片段，任意两个杂交片段由非杂交间隔区段分离，即与天然存在的寡核苷酸序列结合很少或不可能结合的核苷酸或非核苷酸片段。还提供寡核苷酸阵列，其中阵列的至少一个寡核苷酸是部分非杂交寡核苷酸。部分非杂交寡核苷酸用作多功能探针，其中单个部分非杂交寡核苷酸的每个杂交片段用作单个探针。还提供了制备和使用部分非杂交寡核苷酸和由其形成的阵列的方法。阵列制造的特别优选的方法包括使用聚焦的声能。

9. 发明授权

US06707038B2 Method and system using acoustic ejection for selective fluid deposition on a nonuniform sample surface 有权
标题翻译：在不均匀样品表面上选择性流体沉积的声喷射的方法和系统
公开(公告)号：US06707038B2
公开(公告)日：2004-03-16
申请号：US10157755
申请日：2002-05-28
申请人： Richard N. Ellson , Mitchell W. Mutz , Richard Michael Caprioli
发明人： Richard N. Ellson , Mitchell W. Mutz , Richard Michael Caprioli
IPC分类号： H01J4904
CPC分类号： H01J49/0454 , G01N33/54393 , G01N35/1011 , H01J49/0004 , Y10T436/2575
摘要： A method for selectively depositing analysis-enhancing fluid on a sample surface is disclosed. The method involves providing a sample having a surface that exhibits variations in a surface characteristic that corresponds to desirability for receiving an analysis-enhancing fluid. Once a site on the sample surface is selected according to the surface characteristic at the site, focused radiation, typically acoustic radiation, is applied in a manner effective to eject a droplet of the analysis-enhancing fluid from a reservoir. As a result, the droplet is deposited on the sample surface at the selected site. Optionally, the sample at the selected site is analyzed. Systems for selectively depositing analysis-enhancing fluids are also disclosed.
摘要翻译：公开了一种用于在样品表面上选择性地沉积分析增强流体的方法。该方法包括提供具有表现出表现出与分析增强流体接受的期望性相对应的表面特性变化的样品的样品。一旦根据现场的表面特征选择样品表面上的部位，则以有效地从储存器喷射分析增强流体液滴的方式施加聚焦辐射（通常是声辐射）。结果，液滴在所选择的位置沉积在样品表面上。任选地，分析所选位点处的样品。还公开了用于选择性沉积分析增强流体的系统。

10. 发明授权

US06533380B1 Method and apparatus for reducing neighbor cross-talk and increasing robustness of an acoustic printing system against isolated ejector failure 有权
标题翻译：用于减少相邻串扰并增加声学打印系统抵抗隔离喷射器故障的鲁棒性的方法和装置
公开(公告)号：US06533380B1
公开(公告)日：2003-03-18
申请号：US09954308
申请日：2001-09-12
申请人： Babur B. Hadimioglu , Richard N. Ellson
发明人： Babur B. Hadimioglu , Richard N. Ellson
IPC分类号： B41J2145
CPC分类号： B41J2/2139 , B41J2/0451 , B41J2/04525 , B41J2/04575 , B41J2/04595
摘要： An at least two-pass acoustic printing system uses an acoustic printhead having an array of ejectors arranged in rows and columns. Operation of each ejector is individually controllable. To minimize cross-talk errors a first selected ejector in a selected row is identified as an odd ejector of the selected row. Thereafter a first firing sequence of the first selected ejector is generated based on the first selected ejector being identified as odd. Then a second ejector, immediately adjacent the first ejector, is selected and is identified as an even ejector. Thereafter a second firing sequence is generated for the second selected ejector based on the selector being identified as even. The first and second firing sequences result in the first ejector and the second ejector being active during non-concurrent time periods. When a defective ejector of the array is detected, an operable ejector firing to the same substrate area is determined. A firing sequence from or associated with the defective ejector is transferred to be used by the operable ejector wherein the operable ejector fires both its own firing sequence and the firing sequence of the defective ejector.
摘要翻译：至少两声道声音打印系统使用具有排列成行和列的排列阵列的声学打印头。每个喷射器的操作是可以单独控制的。为了最小化串扰错误，所选行中的第一选择的喷射器被识别为所选行的奇数喷射器。此后，基于第一选择的喷射器被识别为奇数来生成第一选择的喷射器的第一喷射序列。然后选择紧邻第一喷射器的第二喷射器，并被识别为均匀喷射器。此后，基于选择器被识别为偶数，为第二选择的喷射器生成第二点火序列。第一和第二发射序列导致第一喷射器和第二喷射器在非并发时间段期间是活动的。当检测到阵列的有缺陷的喷射器时，确定对相同基板区域的可操作的喷射器发射。来自或与有缺陷的喷射器相关联的发射序列被转移以由可操作的喷射器使用，其中可操作的喷射器触发其自身的击发序列和有缺陷的喷射器的击发序列。

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