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1. 发明授权

US4042683A Rifamycins P, Q and U 失效
标题翻译：利福霉素P，Q和U
公开(公告)号：US4042683A
公开(公告)日：1977-08-16
申请号：US601559
申请日：1975-08-04
申请人： Richard J. White , Giancarlo Lancini , Piero Antonini
发明人： Richard J. White , Giancarlo Lancini , Piero Antonini
IPC分类号： C12P17/18 , A61K31/395 , A61P31/04 , C07D498/08 , C12P1/06 , C12R1/365 , A61K35/00
CPC分类号： C07D498/08 , Y10S435/872 , Y10S435/886
摘要： This invention is directed to rifamycin compounds which are produced by fermentation of Nocardia mediterranea ATCC 31064, ATCC 31065 or ATCC 31066 in an aqueous nutrient medium under aerobic conditions. These rifamycins are referred to as rifamycin P, rifamycin Q, rifamycin R and rifamycin U.
摘要翻译：本发明涉及通过在需氧条件下在含水营养培养基中发酵诺卡氏菌ATCC 31064，ATCC 31065或ATCC 31066产生的利福霉素化合物。这些利福霉素被称为利福霉素P，利福霉素Q，利福霉素R和利福霉素U.

2. 发明授权

US4263404A Rifamycin R and microorganisms useful in the production of rifamycins 失效
标题翻译：利福霉素R和可用于生产利福霉素的微生物
公开(公告)号：US4263404A
公开(公告)日：1981-04-21
申请号：US745932
申请日：1976-11-29
申请人： Richard J. White , Giancarlo Lancini , Piero Antonini
发明人： Richard J. White , Giancarlo Lancini , Piero Antonini
IPC分类号： C12P17/18 , A61K31/395 , A61P31/04 , C07D498/08 , C12P1/06 , C12R1/365 , C07D491/06 , A61K35/74 , C12N1/20
CPC分类号： C07D498/08 , Y10S435/872 , Y10S435/886
摘要： Novel rifamycin compounds, designated P, Q, R and U, produced by the fermentation of mutant strains of Streptomyces mediterranei.
摘要翻译：通过发酵Streptomyces mediterranei的突变株产生的新的利福霉素化合物，称为P，Q，R和U。

3. 发明授权

US4267274A Streptomyces mediterranei mutant capable of production of rifamycin B 失效
标题翻译：能够生产利福霉素B的链霉菌地塞米松突变体
公开(公告)号：US4267274A
公开(公告)日：1981-05-12
申请号：US479018
申请日：1974-06-13
申请人： Richard J. White , Giancarlo Lancini
发明人： Richard J. White , Giancarlo Lancini
IPC分类号： C12P17/18 , C12N1/20 , C12R1/465
CPC分类号： C12R1/465 , C12P17/189 , Y10S435/886
摘要： A biologically pure culture of Streptomyces mediterranei mutant strain 18, ATCC.
摘要翻译： Streptomyces mediterranei突变菌株18，ATCC的生物学纯培养物。

4. 发明授权

US06900175B2 Methods of administering dalbavancin for treatment of bacterial infections 有权
标题翻译：给予达巴万星治疗细菌感染的方法
公开(公告)号：US06900175B2
公开(公告)日：2005-05-31
申请号：US10714261
申请日：2003-11-14
申请人： Marco Cavaleri , Daniela Jabes , Timothy Henkel , Adriano Malabarba , Giorgio Mosconi , Martin Stogniew , Richard J. White
发明人： Marco Cavaleri , Daniela Jabes , Timothy Henkel , Adriano Malabarba , Giorgio Mosconi , Martin Stogniew , Richard J. White
IPC分类号： A61K31/70 , A61K31/704 , A61K38/12 , A61K38/14 , A61P31/04 , A61K38/16
CPC分类号： A61K38/14 , A61K31/70 , A61K31/704 , A61K38/00 , A61K2300/00
摘要： The invention provides methods and compositions for treatment of bacterial infections. Methods of the invention include administration of dalbavancin for treatment of a bacterial infection, in particular a Gram-positive bacterial infection of skin and soft tissue. Dosing regimes include once weekly administration of dalbavancin, which often remains at therapeutic levels in the bloodstream for at least one week, providing prolonged therapeutic action against a bacterial infection.
摘要翻译：本发明提供了用于治疗细菌感染的方法和组合物。本发明的方法包括给予达巴万星治疗细菌感染，特别是皮肤和软组织的革兰氏阳性细菌感染。给药方案包括每周一次给予达巴万星，达巴万星通常在血液中保持治疗水平至少一周，为细菌感染提供长时间的治疗作用。

5. 发明授权

US4483246A Apparatus for crushing metal containers and associated method 失效
标题翻译：破碎金属容器及相关方法的设备
公开(公告)号：US4483246A
公开(公告)日：1984-11-20
申请号：US360792
申请日：1982-03-22
申请人： Patrick J. Sullivan , Richard J. White , Lloyd M. Bigley
发明人： Patrick J. Sullivan , Richard J. White , Lloyd M. Bigley
IPC分类号： B30B9/32
CPC分类号： B30B9/32 , B30B9/321 , Y10S100/902
摘要： Apparatus for crushing a plurality of metal containers into a unitary compacted unit and the method associated therewith. A first power operated ram which reciprocates within a compaction chamber. A supply of cans is introduced into the compaction chamber preferably by a predetermined weight measurement. The door between the supply source and the compaction chamber is operated by movement of the ram and its associated platen. Each sequential charge of cans is compressed in the compaction chamber until a compacted unit of predetermined size and weight is established. In another embodiment depressions may be provided to eliminate the need for pallets in handling groups of compacted units. A moveable floor member is opened to permit the compacted unit to be delivered to an underlying discharge chamber. A second powered ram moves the compacted unit out of the compactor while preferably, simultaneously restoring the floor to a closed position.
摘要翻译：用于将多个金属容器破碎成单一压实单元的装置和与其相关联的方法。在压实室内往复运动的第一动力操纵的压头。优选地，通过预定的重量测量将压力供应罐引入压实室。供应源和压实室之间的门通过压头及其相关压板的运动来操作。在压实室中压缩每个顺序的罐装电荷，直到建立了预定尺寸和重量的压实单元。在另一个实施方案中，可以提供凹陷以消除处理压实单元组的托盘的需要。可移动的地板构件被打开以允许压实的单元被输送到下面的排放室。第二动力柱塞将压实单元移出压实机，同时优选地将地板恢复到关闭位置。

6. 发明授权

US5377818A Conveyor belt splice cover 失效
标题翻译：输送带拼接盖
公开(公告)号：US5377818A
公开(公告)日：1995-01-03
申请号：US162225
申请日：1993-12-06
申请人： Richard J. White
发明人： Richard J. White
IPC分类号： F16G3/10 , B65G15/30
CPC分类号： F16G3/10 , Y10T24/16 , Y10T24/1664 , Y10T24/168
摘要： An improved spliced conveyor belt and the method of making it to provide improved impact resistance which comprises laying abutted panels of covering material which contain weft reinforcing strands at a bias angle over the area of the splice so that the reinforcing strands are continuous across the full width of the belt throughout the area of the splice.
摘要翻译：一种改进的拼接输送带及其提供改善的抗冲击性的方法，其包括在接头区域上以偏置角度铺设包含纬纱加强线的覆盖材料的接合板，使得增强线在整个宽度上连续的皮带在整个拼接区域。

7. 发明授权

US5227137A Vacuum clamped multi-sample filtration apparatus 失效
标题翻译：真空夹紧多样品过滤装置
公开(公告)号：US5227137A
公开(公告)日：1993-07-13
申请号：US924795
申请日：1992-08-06
申请人： Patricia C. Monti , Richard J. White , Michael K. Nicholson
发明人： Patricia C. Monti , Richard J. White , Michael K. Nicholson
IPC分类号： B01D29/05 , B01D61/18 , B01L3/00 , C12M1/12 , C12M1/20 , G01N33/53 , G01N33/543
CPC分类号： G01N33/54366 , B01D61/18 , B01L3/5025 , B01L3/50255 , G01N33/5304 , C12M23/12 , Y10S436/809 , Y10T436/255 , Y10T436/2575
摘要： An apparatus for filtering multiple biological samples using a filter membrane is disclosed. The apparatus comprises a base plate, a well plate, a gasket, and a first vacuum member for vacuum-clamping the base plate, well plate, gasket and filter membrane together. The apparatus may further comprise a second vacuum member for drawing the biological samples from the well plate into contact with the filter membrane.
摘要翻译：公开了一种使用过滤膜过滤多个生物样品的装置。该装置包括基板，孔板，垫圈和用于将基板，孔板，垫圈和过滤膜一起真空夹紧的第一真空构件。该装置还可以包括第二真空构件，用于将来自井板的生物样品与过滤膜接触。

8. 发明申请

US20090216663A1 SECURE TRANSACTION MANAGEMENT SYSTEM AND METHOD 审中-公开
标题翻译：安全交易管理系统和方法
公开(公告)号：US20090216663A1
公开(公告)日：2009-08-27
申请号：US12090897
申请日：2006-10-23
申请人： Richard J. White
发明人： Richard J. White
IPC分类号： G06Q10/00 , G06K19/00 , G01C21/00 , G06N5/02 , G06F17/30 , G06F17/40
CPC分类号： G06Q10/08 , G06Q10/087
摘要： A system (200) for managing a secure transaction comprises a secure code generator (210) for generating a first unique code and a second unique code, a database (209) for storing said first code and said second code, means for issuing (208) said first code to a first party (201) and said second code to a second party (211) and an interface (205) for inputting said first and second codes to the database (209).
摘要翻译：一种用于管理安全交易的系统（200）包括用于产生第一唯一码和第二唯一码的安全码产生器（210），用于存储所述第一码和所述第二码的数据库（209），用于发出（208 ）将第一代码发送给第一方（201），并将所述第二代码传送给第二方（211）和用于将所述第一和第二代码输入到数据库（209）的接口（205）。

9. 外观设计

USD351797S Digital clock 失效
公开(公告)号：USD351797S
公开(公告)日：1994-10-25
申请号：US781292
申请日：1991-10-23
申请人： Richard J. White
设计人： Richard J. White

10. 发明授权

US4824865A Treatment of skin disorders 失效
标题翻译：治疗皮肤病
公开(公告)号：US4824865A
公开(公告)日：1989-04-25
申请号：US002046
申请日：1987-01-12
申请人： Paul A. Bowser , Richard J. White
发明人： Paul A. Bowser , Richard J. White
IPC分类号： A61K8/00 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/37 , A61K31/20 , A61K31/23 , A61P17/00 , A61P31/04 , A61Q5/00 , A61Q5/02 , A61Q19/00 , C07C59/01 , C07C59/185
CPC分类号： A61K31/23 , A61K31/20 , A61K8/365 , A61K8/37 , A61K8/375 , A61Q19/00 , A61Q5/006 , A61Q5/02 , A61Q7/00 , A61K2800/28 , Y10S514/858
摘要： The use of a curative agent chosen from 2-hydroxyoctanoic acid, 2-ketooctanoic acid and certain esters thereof in the preparation of a pharmaceutical composition for the treatment of skin disorders such as Ichthyosiform dermatoses, Conradi's syndrome, Localized hyperkeratotic conditions, Dandruff, Callous forming disorders, Psoriasis, Eczema, Xerosis, Warts, Tinea pedis, Pityriasis, Lichen planus and simplex chronicus, Darier's disease, Pruritus, Seborrhoeic conditions and Scabies.
摘要翻译：选自2-羟基辛酸，2-酮辛酸及其某些酯的治疗剂在制备用于治疗皮肤病的药物组合物中的用途，所述药物组合物用于治疗皮肤病，例如Ichthyosiform皮肤病，Conradi综合征，局部角化过度症状，头皮屑，形成脂蛋白疾病，牛皮癣，湿疹，Xerosis，疣，足癣，糠疹，扁平苔藓和单纯疱疹，达里氏病，瘙痒症，脂溢性病症和Sc疮。

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