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1. 发明授权

US07520884B2 Methods for performing gastroplasty 有权
标题翻译：进行胃成形术的方法
公开(公告)号：US07520884B2
公开(公告)日：2009-04-21
申请号：US10841233
申请日：2004-05-07
申请人： Lee L. Swanstrom , Richard C. Ewers , Tracy D. Maahs , Eugene G. Chen , Vahid Saadat
发明人： Lee L. Swanstrom , Richard C. Ewers , Tracy D. Maahs , Eugene G. Chen , Vahid Saadat
IPC分类号： A61B17/08
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/085 , A61B17/1114 , A61B2017/0496 , A61B2017/081 , A61F5/0086
摘要： Methods for performing gastroplasty include reducing the effective volume or cross-sectional area of the stomach via approximation of gastric tissue. Such reduction preferably is achieved endoluminally, either with or without laparoscopic ports. In one variation, a sleeve, pouch, Magenstrasse and Mill, Vertical Banded Gastroplasty (“VBG”), etc.,is formed within the stomach by approximating opposing anterior and posterior segments or ridges of the stomach wall at locations inferior to the gastroesophageal junction. In another variation, opposing walls of the stomach are approximated at a plurality of substantially random locations to reduce an effective volume of the stomach. In yet another variation, both a sleeve and random approximations are formed, the random approximations preferably disposed in a portion of the stomach excluded by the sleeve. In still another variation, opposing walls of the stomach are approximated over significant lengths at random or specified locations.
摘要翻译：进行胃成形术的方法包括通过胃组织的近似来减小胃的有效体积或横截面积。这种减少优选是在腹腔镜下或腹腔镜下进行的。在一个变型中，通过在胃壁下方的胃壁的相邻的前部和后部区段或脊部近似形成在胃内形成套筒，袋，Magenstrasse和Mill，垂直带状胃成形术（“VBG”）等。在另一个变型中，胃的相对壁在多个基本上随机的位置近似，以减少胃的有效体积。在另一个变型中，形成套筒和随机近似，随机近似优选地设置在由套筒排除的胃的一部分中。在另一个变体中，胃的相对的壁在随机或指定的位置处以相当长的长度近似。

2. 发明授权

US07128708B2 Shape lockable apparatus and method for advancing an instrument through unsupported anatomy 有权
公开(公告)号：US07128708B2
公开(公告)日：2006-10-31
申请号：US10173203
申请日：2002-06-13
申请人： Vahid Saadat , Richard C. Ewers , Eugene G. Chen
发明人： Vahid Saadat , Richard C. Ewers , Eugene G. Chen
IPC分类号： A61B1/00
CPC分类号： A61B1/00154 , A61B1/00078 , A61B1/0008 , A61B1/00082 , A61B1/00105 , A61B1/00135 , A61B1/0052 , A61B1/0055 , A61B1/0058 , A61B1/008 , A61B1/31 , A61B1/32
摘要： Apparatus and methods are provided for placing and advancing a diagnostic or therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube, a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The overtube may be selectively stiffened to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.

3. 发明授权

US06837847B2 Shape lockable apparatus and method for advancing an instrument through unsupported anatomy 有权
标题翻译：形状可锁定装置和方法，用于通过不支持的解剖结构推进器械
公开(公告)号：US06837847B2
公开(公告)日：2005-01-04
申请号：US10173238
申请日：2002-06-13
申请人： Richard C. Ewers , Vahid Saadat , Eugene G. Chen
发明人： Richard C. Ewers , Vahid Saadat , Eugene G. Chen
IPC分类号： A61B1/005 , A61B1/008 , A61B1/01 , A61B1/31 , A61B1/32 , A61B1/04
CPC分类号： A61B1/00154 , A61B1/00078 , A61B1/0008 , A61B1/00082 , A61B1/00105 , A61B1/00135 , A61B1/0052 , A61B1/0055 , A61B1/0058 , A61B1/008 , A61B1/31 , A61B1/32
摘要： Apparatus and methods are provided for placing and advancing a diagnostic or therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube, a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The overtube may be selectively stiffened to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.
摘要翻译：提供了设备和方法，用于将诊断或治疗仪器放置并行进在曲折或无支撑的解剖结构的中空身体器官中，包括手柄，外套管，具有无创尖端的远侧区域。外套管可以从手柄移除，并且具有相对于把手以一定角度设置的纵向轴线。外套管可以选择性地加强，以减少由诊断或治疗仪器的前进引起的器官膨胀。远端区域允许由诊断或治疗仪器的偏转引起的外套管的被动转向，而无创伤的尖端在操纵诊断或治疗仪器期间防止器官的壁被卡住或夹住。

4. 发明授权

US07955253B2 Apparatus and methods for achieving endoluminal access 有权
标题翻译：用于实现腔内通路的装置和方法
公开(公告)号：US07955253B2
公开(公告)日：2011-06-07
申请号：US11311999
申请日：2005-12-19
申请人： Richard C. Ewers , Boris Reydel , Eugene G. Chen , Vahid Saadat
发明人： Richard C. Ewers , Boris Reydel , Eugene G. Chen , Vahid Saadat
IPC分类号： A61B1/00
CPC分类号： A61B1/00149 , A61B1/00082 , A61B1/00147 , A61B1/31
摘要： The present invention provides methods and apparatus for pleating at least a portion of a patient's body lumen, such as the colon. Pleating is achieved via relative motion between an endoscope and a flexible conduit having an engagement element configured to reversibly engage the body lumen.
摘要翻译：本发明提供了用于打褶患者体腔（如结肠）的至少一部分的方法和装置。褶皱通过内窥镜和具有配置为可逆地接合体腔的接合元件的柔性导管之间的相对运动来实现。

5. 发明授权

US07744613B2 Apparatus and methods for forming and securing gastrointestinal tissue folds 有权
公开(公告)号：US07744613B2
公开(公告)日：2010-06-29
申请号：US10734547
申请日：2003-12-12
申请人： Richard C. Ewers , Vahid Saadat , Kenneth J. Michlitsch , Chris A. Rothe , Rodney A. Brenneman , Cang C. Lam , Eugene G. Chen
发明人： Richard C. Ewers , Vahid Saadat , Kenneth J. Michlitsch , Chris A. Rothe , Rodney A. Brenneman , Cang C. Lam , Eugene G. Chen
IPC分类号： A61B17/08 , A61B17/04
CPC分类号： A61B1/0055 , A61B1/00135 , A61B1/018 , A61B1/2736 , A61B1/31 , A61B17/00234 , A61B17/0218 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/062 , A61B17/0625 , A61B17/0644 , A61B17/29 , A61B17/295 , A61B17/3421 , A61B17/3468 , A61B17/3478 , A61B2017/00269 , A61B2017/003 , A61B2017/00353 , A61B2017/00827 , A61B2017/0404 , A61B2017/0417 , A61B2017/0419 , A61B2017/0443 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/061 , A61B2017/06176 , A61B2017/0649 , A61B2017/2905 , A61B2017/2927 , A61B2017/2943 , A61B2017/3445 , A61B2017/3488 , A61B2090/3614 , A61F5/0086
摘要： Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point and moving the first tissue contact point from a position initially distal to, or in line with, a second tissue contact point to a position proximal of the second contact point, thereby forming the tissue fold, and extending an anchor assembly through the tissue fold from a vicinity of the second tissue contact point. Adjustable anchor assemblies; as well as anchor delivery systems, shape-lockable guides and methods for endoluminally performing medical procedures, such as gastric reduction, treatment of gastroesophageal reflux disease, resection of lesions, and treatment of bleeding sites; are also provided.

6. 发明授权

US07637905B2 Endoluminal tool deployment system 有权
标题翻译：腔内工具部署系统
公开(公告)号：US07637905B2
公开(公告)日：2009-12-29
申请号：US10346709
申请日：2003-01-15
申请人： Vahid Saadat , Richard C. Ewers , Eugene G. Chen , David Miller
发明人： Vahid Saadat , Richard C. Ewers , Eugene G. Chen , David Miller
IPC分类号： A61B17/00 , A61B1/00
CPC分类号： A61B17/00234 , A61B1/0055 , A61B1/0057 , A61B1/018 , A61B1/313 , A61B2017/003 , A61B2017/00323 , A61B2017/00349 , A61B2017/2906 , A61B2017/3445 , A61B2090/306 , A61B2090/508 , A61M25/0043 , A61M25/0105 , A61M25/0147 , A61M2025/0096
摘要： Systems, devices and methods are provided for endoscopic procedures involving tissue manipulations beyond the capabilities of traditional endoscopic instruments. Embodiments of the systems include an elongated main body having a scope therethrough and at least one steerable tool arm which extends from the distal end of the main body. In preferred embodiments, the system includes two tool arms, each arm steerable to form a curve laterally outward which then bends laterally inward so that the arms form an angular shape. In addition, end effectors extend from the distal ends of each tool arm for use in manipulation of tissue. The angular shape brings the end effectors together in view of the scope for cooperative movements which are continuously visible by the surgeon. In addition, the tool arms may be steerable in any additional direction and may be rotatable to allow grasping, elevation and more complex manipulation of tissue.
摘要翻译：提供的系统，装置和方法用于内窥镜手术，其涉及组织操作超出传统内窥镜仪器的能力。系统的实施例包括具有穿过其中的一个细长主体和从该主体的远端延伸的至少一个可操纵的工具臂。在优选实施例中，系统包括两个工具臂，每个臂可转向以横向向外形成曲线，然后横向向内弯曲，使得臂形成角形。另外，末端执行器从每个工具臂的远端延伸以用于组织的操作。考虑到外科医生连续可见的协作运动的范围，角形状使末端执行器结合在一起。此外，工具臂可以在任何附加方向上是可操纵的并且可以是可旋转的，以允许组织的抓握，升高和更复杂的操纵。

7. 发明授权

US06790173B2 Shape lockable apparatus and method for advancing an instrument through unsupported anatomy 有权
公开(公告)号：US06790173B2
公开(公告)日：2004-09-14
申请号：US10173227
申请日：2002-06-13
申请人： Vahid Saadat , Richard C. Ewers , Eugene G. Chen
发明人： Vahid Saadat , Richard C. Ewers , Eugene G. Chen
IPC分类号： A61B104
CPC分类号： A61B1/00154 , A61B1/00078 , A61B1/0008 , A61B1/00082 , A61B1/00105 , A61B1/00135 , A61B1/0052 , A61B1/0055 , A61B1/0058 , A61B1/008 , A61B1/31 , A61B1/32
摘要： Apparatus and methods are provided for placing and advancing a diagnostic or therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube, a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The overtube may be selectively stiffened to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.

8. 发明授权

US08262676B2 Apparatus and methods for forming gastrointestinal tissue approximations 有权
标题翻译：用于形成胃肠组织近似的装置和方法
公开(公告)号：US08262676B2
公开(公告)日：2012-09-11
申请号：US12562927
申请日：2009-09-18
申请人： Richard C. Ewers , Boris Reydel , Cang Lam , Eugene G. Chen , Brent D. Seybold , Rodney Brenneman , Vahid Saadat
发明人： Richard C. Ewers , Boris Reydel , Cang Lam , Eugene G. Chen , Brent D. Seybold , Rodney Brenneman , Vahid Saadat
IPC分类号： A61B17/00 , A61B17/10 , A61B17/12 , A61B17/125
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/0487 , A61B17/0644 , A61B17/29 , A61B17/3421 , A61B17/3468 , A61B17/3478 , A61B2017/0404 , A61B2017/0417 , A61B2017/0419 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/061 , A61B2017/3445 , A61B2017/3488
摘要： Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point, moving the first tissue contact point from a position initially distal to a second tissue contact point to a position proximal of the second contact point to form a tissue fold, and extending an anchor assembly through the tissue fold near the second tissue contact point.
摘要翻译：提供了设备和方法，用于通过在第一组织接触点处接合组织来形成胃肠组织折叠，将第一组织接触点从最初远端到第二组织接触点的位置移动到第二接触点的近侧的位置，以形成组织折叠，并且使锚固组件穿过第二组织接触点附近的组织褶皱延伸。

9. 发明授权

US08343175B2 Apparatus and methods for forming and securing gastrointestinal tissue folds 有权
公开(公告)号：US08343175B2
公开(公告)日：2013-01-01
申请号：US12767731
申请日：2010-04-26
申请人： Richard C. Ewers , Vahid Saadat , Kenneth J. Michlitsch , Chris A. Rothe , Rodney C. Brenneman , Cang C. Lam , Eugene G. Chen
发明人： Richard C. Ewers , Vahid Saadat , Kenneth J. Michlitsch , Chris A. Rothe , Rodney C. Brenneman , Cang C. Lam , Eugene G. Chen
IPC分类号： A61B17/08
CPC分类号： A61B1/0055 , A61B1/00135 , A61B1/018 , A61B1/2736 , A61B1/31 , A61B17/00234 , A61B17/0218 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/062 , A61B17/0625 , A61B17/0644 , A61B17/29 , A61B17/295 , A61B17/3421 , A61B17/3468 , A61B17/3478 , A61B2017/00269 , A61B2017/003 , A61B2017/00353 , A61B2017/00827 , A61B2017/0404 , A61B2017/0417 , A61B2017/0419 , A61B2017/0443 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/061 , A61B2017/06176 , A61B2017/0649 , A61B2017/2905 , A61B2017/2927 , A61B2017/2943 , A61B2017/3445 , A61B2017/3488 , A61B2090/3614 , A61F5/0086
摘要： Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point and moving the first tissue contact point from a position initially distal to, or in line with, a second tissue contact point to a position proximal of the second contact point, thereby forming the tissue fold, and extending an anchor assembly through the tissue fold from a vicinity of the second tissue contact point. Adjustable anchor assemblies; as well as anchor delivery systems, shape-lockable guides and methods for endoluminally performing medical procedures, such as gastric reduction, treatment of gastroesophageal reflux disease, resection of lesions, and treatment of bleeding sites; are also provided.

10. 发明授权

US08087413B2 Attenuation of environmental parameters on a gastric lumen 有权
标题翻译：胃管内环境参数的衰减
公开(公告)号：US08087413B2
公开(公告)日：2012-01-03
申请号：US11035702
申请日：2005-01-14
申请人： Vahid Saadat , Ruey-Feng Peh , Richard C. Ewers , Eugene G. Chen
发明人： Vahid Saadat , Ruey-Feng Peh , Richard C. Ewers , Eugene G. Chen
IPC分类号： A61B19/00 , A61B17/08 , A61B17/04 , A61F2/04 , A61L17/00
CPC分类号： A61B17/0469 , A61B17/00491 , A61B17/0401 , A61B17/0487 , A61B17/1114 , A61B2017/00349 , A61B2017/00495 , A61B2017/0406 , A61B2017/0454 , A61B2017/0464
摘要： The attenuation or isolation of environmental parameters on a gastric lumen is described herein. Once tissue plications are formed into a gastric lumen or sleeve within a stomach, the newly formed lumen is subjected to a multitude of fluctuating stresses or pressure from food or fluids passing therethrough, from naturally-occurring contractions, and/or from changes in pH levels from caustic stomach acids and hormones. The tissue interface between these plications can be isolated from such environmental fluctuations, or the fluctuations can be attenuated, by a number of methods. One example is to place a gastric stent or sleeve within the newly formed lumen. Another example is to utilize multiple rows of anchors, clips, or sutures along the interface. Alternatively, bio-adhesives can be dispensed to buttress the tissue interface. In another variation, the tissue can be approximated in different configurations which effectively reduce or isolate the adhered tissue region.
摘要翻译：本文描述了在胃腔上的环境参数的衰减或分离。一旦组织消融在胃内形成胃腔或套管，则新形成的内腔经受来自通过其的食物或液体的多种波动的应力或压力，从天然存在的收缩和/或pH水平的变化从苛性胃酸和激素。可以通过多种方法将这些斑点之间的组织界面与这种环境波动隔离，或者波动可以减弱。一个例子是将胃支架或套管放置在新形成的内腔内。另一个例子是沿着界面使用多行锚，剪辑或缝线。或者，可以分配生物粘合剂以支撑组织界面。在另一个实施方式中，可以以有效地减少或隔离粘附的组织区域的不同配置来近似组织。

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