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1. 发明申请

US20090123050A1 Method and system for automatic quantification of aortic valve function from 4D computed tomography data using a physiological model 有权
标题翻译：使用生理模型从4D计算机断层扫描数据自动定量主动脉瓣功能的方法和系统
公开(公告)号：US20090123050A1
公开(公告)日：2009-05-14
申请号：US12288215
申请日：2008-10-17
申请人： Razvan Ionasec , Bogdan Georgescu , Helene C. Houle , Sebastian Vogt , Michael Scheuering , Estelle Camus , Dorin Comaniciu
发明人： Razvan Ionasec , Bogdan Georgescu , Helene C. Houle , Sebastian Vogt , Michael Scheuering , Estelle Camus , Dorin Comaniciu
IPC分类号： G06K9/00
CPC分类号： G06K9/00 , G06K2209/051 , G06T7/0016 , G06T7/251 , G06T17/20 , G06T2207/10076 , G06T2207/10136 , G06T2207/20076 , G06T2207/20081 , G06T2207/30048
摘要： A method and system for modeling the aortic valve in 4D image data, such as 4D CT and echocardiography, is disclosed. An initial estimate of a physiological aortic valve model is determined for at least one reference frame of a 4D image sequence based on anatomic features in the reference frame. The initial estimate is refined to generate a final estimate in the reference frame. A dynamic model of the aortic valve is then generated by estimating the physiological aortic valve model for each remaining frame of the 4D image sequence based on the final estimate in the reference frame. The aortic valve can be quantitatively evaluated using the dynamic model.
摘要翻译：公开了用于4D图像数据建模主动脉瓣的方法和系统，如4D CT和超声心动图。基于参考系中的解剖特征，为4D图像序列的至少一个参考帧确定生理主动脉瓣模型的初始估计。改进初始估计以在参考系中产生最终估计。然后通过基于参考框架中的最终估计估计4D图像序列的每个剩余帧的生理主动脉瓣模型来生成主动脉瓣的动态模型。主动脉瓣可以使用动态模型进行定量评估。

2. 发明授权

US08009887B2 Method and system for automatic quantification of aortic valve function from 4D computed tomography data using a physiological model 有权
标题翻译：使用生理模型从4D计算机断层扫描数据自动定量主动脉瓣功能的方法和系统
公开(公告)号：US08009887B2
公开(公告)日：2011-08-30
申请号：US12288215
申请日：2008-10-17
申请人： Razvan Ionasec , Bogdan Georgescu , Helene C. Houle , Sebastian Vogt , Michael Scheuering , Estelle Camus , Dorin Comaniciu
发明人： Razvan Ionasec , Bogdan Georgescu , Helene C. Houle , Sebastian Vogt , Michael Scheuering , Estelle Camus , Dorin Comaniciu
IPC分类号： G06K9/00
CPC分类号： G06K9/00 , G06K2209/051 , G06T7/0016 , G06T7/251 , G06T17/20 , G06T2207/10076 , G06T2207/10136 , G06T2207/20076 , G06T2207/20081 , G06T2207/30048
摘要： A method and system for modeling the aortic valve in 4D image data, such as 4D CT and echocardiography, is disclosed. An initial estimate of a physiological aortic valve model is determined for at least one reference frame of a 4D image sequence based on anatomic features in the reference frame. The initial estimate is refined to generate a final estimate in the reference frame. A dynamic model of the aortic valve is then generated by estimating the physiological aortic valve model for each remaining frame of the 4D image sequence based on the final estimate in the reference frame. The aortic valve can be quantitatively evaluated using the dynamic model.
摘要翻译：公开了用于4D图像数据建模主动脉瓣的方法和系统，如4D CT和超声心动图。基于参考系中的解剖特征，为4D图像序列的至少一个参考帧确定生理主动脉瓣模型的初始估计。改进初始估计以在参考系中产生最终估计。然后通过基于参考框架中的最终估计估计4D图像序列的每个剩余帧的生理主动脉瓣模型来生成主动脉瓣的动态模型。主动脉瓣可以使用动态模型进行定量评估。

3. 发明授权

US09339317B2 Mixing device for prepack vacuum cementing system, vacuum cementing system, and method 有权
标题翻译：预制真空胶合系统混合装置，真空固井系统及方法
公开(公告)号：US09339317B2
公开(公告)日：2016-05-17
申请号：US13822546
申请日：2011-08-10
申请人： Sebastian Vogt , Hubert Buechner
发明人： Sebastian Vogt , Hubert Buechner
IPC分类号： B01F13/06 , A61B17/88 , B01F7/00 , B01F13/00 , B01F15/00 , B01F15/02 , B29B7/10 , B01F7/16
CPC分类号： A61B17/88 , A61B17/8822 , A61B17/8827 , B01F7/007 , B01F7/00716 , B01F7/16 , B01F13/0018 , B01F15/00071 , B01F15/00506 , B01F15/00798 , B01F15/00974 , B01F15/0278 , B29B7/10
摘要： A mixing device, for a mixable material, has at least one cartridge and a closure piece. The cartridge contains a first component of the mixable material and has a cartridge head in which at least one air opening is arranged, and the closure piece is arranged on the cartridge head in such a way that the at least one air opening in the cartridge head can be closed and opened by the closure piece. The closure piece is mounted so as to be rotatable or slideable relative to the cartridge head, and a connection extends through the cartridge head or a cartridge wall into the interior of the cartridge and connects the interior of the cartridge to a container for a second component of the mixable material.
摘要翻译：用于可混合材料的混合装置具有至少一个筒和封闭件。墨盒包含可混合材料的第一部件，并且具有墨盒头，其中布置有至少一个空气开口，并且封闭件以这样的方式设置在盒头部上，使得盒头中的至少一个空气开口可以由封闭件封闭并打开。封闭件安装成相对于盒头可旋转或可滑动，并且连接件通过盒头或盒壁延伸到盒的内部，并将盒的内部连接到用于第二部件的容器的可混合材料。

4. 发明授权

US09272803B2 Vacuum cementing system 有权
标题翻译：真空固井系统
公开(公告)号：US09272803B2
公开(公告)日：2016-03-01
申请号：US13808452
申请日：2011-06-10
申请人： Sebastian Vogt , Hubert Buechner , Tim Schnieber
发明人： Sebastian Vogt , Hubert Buechner , Tim Schnieber
IPC分类号： B65B69/00 , A61B17/88 , B01F11/00 , B01F13/00 , B01F15/02 , A61F2/30 , A61F2/46
CPC分类号： B65B69/00 , A61B17/8833 , A61F2002/30561 , A61F2002/4685 , B01F11/0082 , B01F13/0023 , B01F15/0206 , B01F15/0258 , B65B69/0008
摘要： A vacuum cementing system has at least one cement powder cartridge and a container-opening system. The container-opening system has at least one container for at least one liquid and/or at least one powder, an opening device, and an outlet opening for applying a negative pressure. When a negative pressure is being applied, the opening device is mobile relative to at least a part of the at least one container. The vacuum cementing system has a means for connecting the cement powder cartridge to the at least one container and utilizes necessary vacuum for automatically opening the at least one container.
摘要翻译：真空固井系统具有至少一个水泥粉末盒和容器开启系统。容器开启系统具有用于至少一种液体和/或至少一种粉末，开启装置和用于施加负压的出口开口的至少一个容器。当施加负压时，打开装置相对于至少一个容器的至少一部分是可移动的。真空固井系统具有用于将水泥粉末筒连接到至少一个容器并利用必要的真空来自动打开至少一个容器的装置。

5. 发明授权

US09073081B2 Dispensing device for pasty materials 有权
标题翻译：糊状物料分配装置
公开(公告)号：US09073081B2
公开(公告)日：2015-07-07
申请号：US13096062
申请日：2011-04-28
申请人： Sebastian Vogt , Hubert Büchner
发明人： Sebastian Vogt , Hubert Büchner
IPC分类号： B05C17/015 , A61B17/88 , B05C17/005 , A61B17/00
CPC分类号： B05C17/015 , A61B17/8822 , A61B17/8825 , A61B17/8827 , A61B2017/0023 , B05C17/00553 , B05C17/00559
摘要： A dispensing device for cartridges having a connection for supplying a pressurized gas, a base body, in which at least one passage and/or channel extends through which the pressurized gas can be guided to a first cartridge connector for connecting a cartridge. The first cartridge connector has a first opening towards the passage and/or the front channel such that a cartridge content can be expelled from the cartridge through application of the pressurized gas to a cartridge when the cartridge is arranged in the cartridge connector, wherein a second cartridge connector having a larger cross-section and a second opening is arranged at a front edge of the first cartridge connector The second cartridge connector is suitable for connecting a larger cartridge, and wherein the second opening of the second cartridge connector is sufficiently large to allow a cartridge to be connected to the first cartridge connector proceeding through the second opening.
摘要翻译：用于具有用于供应加压气体的连接的筒的分配装置，基体，其中至少一个通道和/或通道延伸，加压气体可以通过该通道和/或通道被引导到用于连接盒的第一盒连接器。第一盒式连接器具有朝向通道和/或前通道的第一开口，使得当盒被布置在盒连接器中时，盒内容物可以通过将加压气体施加到盒而从盒排出，其中第二具有较大横截面的盒式连接器和第二开口布置在第一盒式连接器的前边缘处。第二盒式连接器适于连接较大的盒，并且其中第二盒式连接器的第二开口足够大以允许要连接到通过第二开口的第一盒式连接器的盒。

6. 发明授权

US08865777B2 Kit and method for producing bone cement 有权
标题翻译：用于生产骨水泥的套件和方法
公开(公告)号：US08865777B2
公开(公告)日：2014-10-21
申请号：US13558579
申请日：2012-07-26
申请人： Sebastian Vogt , Hubert Büchner
发明人： Sebastian Vogt , Hubert Büchner
IPC分类号： A61K6/083 , A61L24/04 , A61L27/16 , A61L27/26 , A61L27/50 , A61L24/00 , A61L24/06
CPC分类号： A61L24/043 , A61K6/005 , A61K6/0073 , A61K6/083 , A61L24/001 , A61L24/0089 , A61L24/06 , A61L27/16 , A61L27/26 , A61L27/50 , A61L2430/02 , C08L33/08 , C08L33/10 , C08L33/14
摘要： A kit for producing bone cement includes at least one paste A and one paste B. Paste A contains at least one monomer (a1) for radical polymerization; at least one polymer (a2) insoluble in monomer (a1); at least one polymer (a3) soluble in monomer (a1); and at least one radical polymerization initiator (a4). The weight ratio of the at least one polymer (a2) to the at least one polymer (a3) is at least 2 to 1. Paste B contains at least one monomer (b1) for radical polymerization; at least one polymer (b2) and at least one accelerator (b3) soluble in monomer (b1); and optionally a polymer (b4) insoluble in monomer (b1). The maximum quantity of polymer (b4) is 5% by weight, relative to the total weight of paste B. The weight ratio of polymer (b4) to the at least one polymer (b2) is no more than 0.2.
摘要翻译：用于生产骨水泥的试剂盒包括至少一种糊剂A和一种糊剂B.糊剂A含有至少一种用于自由基聚合的单体（a1）至少一种不溶于单体（a1）的聚合物（a2）; 至少一种可溶于单体（a1）的聚合物（a3）; 和至少一种自由基聚合引发剂（a4）。至少一种聚合物（a2）与至少一种聚合物（a3）的重量比为至少2:1。糊剂B含有至少一种单体（b1）用于自由基聚合; 至少一种聚合物（b2）和至少一种可溶于单体（b1）的促进剂（b3）; 和任选的不溶于单体（b1）的聚合物（b4）。聚合物（b4）的最大量相对于糊料B的总重量为5重量％。聚合物（b4）与至少一种聚合物（b2）的重量比不大于0.2。

7. 发明授权

US08596499B2 Cartridge system with rotatable closure and dispensing tube 有权
标题翻译：墨盒系统可旋转封闭和分配管
公开(公告)号：US08596499B2
公开(公告)日：2013-12-03
申请号：US13096233
申请日：2011-04-28
申请人： Sebastian Vogt , Hubert Büchner , Tim Schnieber
发明人： Sebastian Vogt , Hubert Büchner , Tim Schnieber
IPC分类号： B67D7/70 , B67D7/78 , B67D3/00 , B67D7/06 , B65D35/54 , B65D88/54 , B65D47/20 , G01F11/00 , A61C5/04
CPC分类号： B65D81/325 , A61B17/8833 , B05C11/1031 , B05C17/00516 , B05C17/00553 , B05C17/01
摘要： Cartridge systems for application of a material have at least one cartridge having cartridge walls, a cartridge head having at least one opening in the cartridge head, and a bracket arranged on the cartridge head. A valve is mounted in rotatable manner in the bracket and has at least one passage through the valve that is connected to an outlet opening of the valve. In a closed position, the valve closes the at least one opening of at least one cartridge in a sealed manner. The at least one passage of the valve is connected to the at least one opening when the valve is located in an open position such that the cartridge content is squeezable out of the at least one cartridge through the outlet opening, and further wherein the valve is configured to be transitioned from a closed position to an open position through a rotation of the valve about an axis of symmetry of the valve.
摘要翻译：用于施加材料的盒式系统具有至少一个具有盒壁的盒，具有盒头中的至少一个开口的盒头和布置在盒头上的支架。阀以可旋转的方式安装在支架中，并且具有至少一个通过阀的通道，其连接到阀的出口开口。在关闭位置，阀以密封方式关闭至少一个盒的至少一个开口。当阀位于打开位置时，阀的至少一个通道连接到至少一个开口，使得盒内容物可通过出口开口挤压出至少一个盒，而且其中阀是构造成通过所述阀围绕所述阀的对称轴的旋转而从关闭位置转换到打开位置。

8. 发明申请

US20130175290A1 SYNCHRONISED DISPENSING DEVICE, METHOD FOR SYNCHRONISING FLOWS, AND METHOD FOR MIXING A MIXABLE MATERIAL 有权
标题翻译：同步分配装置，用于同步流动的方法和混合混合材料的方法
公开(公告)号：US20130175290A1
公开(公告)日：2013-07-11
申请号：US13823340
申请日：2011-08-10
申请人： Sebastian Vogt , Hubert Buechner
发明人： Sebastian Vogt , Hubert Buechner
IPC分类号： B01F3/08
CPC分类号： B01F3/08 , B01F5/0602 , B01F15/0087 , B01F15/0226 , B01F15/0243 , B01F15/0416 , B01F2215/0029 , B05C17/00556 , B05C17/00566 , B05C17/015 , G05D11/005
摘要： A cartridge system for mixing and applying a mixable material has a discharge opening and at least two cartridges which have interiors delimited in some areas by a cartridge head. A device regulates streams from the cartridges, is arranged on the cartridge head and has an outflow opening and conveying mechanisms for conveying the starting components to the outflow opening. Each conveying mechanism has a connection to an interior of a cartridge, which has a cartridge opening, and is arranged rotatably in the device. Volumetric flows of the components are defined by the angular velocities of the conveying mechanisms, and the conveying mechanisms are coupled to each other in such a way that the ratio of the angular velocities relative to each other is fixed, such that a defined mixing ratio can be generated at the outflow opening.
摘要翻译：用于混合和施加可混合材料的盒系统具有排出开口和至少两个盒，其具有通过盒头在一些区域内部限定的内部。设备调节来自墨盒的流，布置在墨盒头部上，并具有用于将起始部件输送到流出开口的流出开口和输送机构。每个传送机构具有与盒的内部的连接，其具有盒开口，并且可旋转地布置在装置中。部件的体积流量由传送机构的角速度限定，并且输送机构以相对于彼此的角速度比固定的方式彼此连接，使得限定的混合比可以在流出口产生。

9. 发明申请

US20130172896A1 DISPENSING DEVICE FOR BONE CEMENT 有权
标题翻译：骨水泥分配装置
公开(公告)号：US20130172896A1
公开(公告)日：2013-07-04
申请号：US13822685
申请日：2011-09-21
申请人： Sebastian Vogt , Hubert Buechner
发明人： Sebastian Vogt , Hubert Buechner
IPC分类号： A61B17/88
CPC分类号： A61B17/8802 , A61B17/8822 , A61B17/8825 , B05C17/0052 , B05C17/00553 , B05C17/00596 , B05C17/015
摘要： A discharge device discharges the content of a container by applying a compressed gas. The device has a housing, at least one compressed gas container, an operating device for setting a gas flow from the compressed gas container and an opening means for opening the compressed gas container. The opening means is movable in relation to the compressed gas container, and the device has a holder for securing the container on the device. The holder is in operative connection with the opening means in such a way that securing the container on the holder brings about a movement of the opening means in relation to the compressed gas container that opens the compressed gas container.
摘要翻译：排出装置通过施加压缩气体来排出容器的内容物。该装置具有壳体，至少一个压缩气体容器，用于设定来自压缩气体容器的气体流动的操作装置和用于打开压缩气体容器的打开装置。打开装置相对于压缩气体容器是可移动的，并且该装置具有用于将容器固定在装置上的保持器。保持器与打开装置操作连接，使得将容器固定在保持器上使打开装置相对于打开压缩气体容器的压缩气体容器移动。

10. 发明授权

US08092824B2 Antibiotic coating of implants 有权
标题翻译：植入物的抗生素涂层
公开(公告)号：US08092824B2
公开(公告)日：2012-01-10
申请号：US11335323
申请日：2006-01-19
申请人： Klaus-Dieter Kühn , Sebastian Vogt , Matthias Schnabelrauch
发明人： Klaus-Dieter Kühn , Sebastian Vogt , Matthias Schnabelrauch
IPC分类号： A61F2/02
CPC分类号： A61L27/54 , A61L27/28 , A61L2300/404 , A61L2300/606
摘要： An antibiotic coating of implants is described, which is characterized in that the coating comprises at least one saturated, organic, hydrophobic, low molecular matrix former whose melting point is in the temperature range of 45° C. to 100° C., in which a low molecular, hydrophobic additive is dissolved and that an antibiotic/antibiotics is/are suspended in the mixture of matrix former and additive and/or in which an antibiotic/antibiotics miscible with a mixture of matrix former and additive is/are dissolved.
摘要翻译：描述了植入物的抗生素涂层，其特征在于该涂层包含至少一种饱和的，有机的，疏水的，低分子量的基质，其熔点在45℃至100℃的温度范围内，其中溶解低分子疏水性添加剂，并且将抗生素/抗生素悬浮在基质前体和添加剂的混合物中，和/或其中溶解有与基质前体和添加剂的混合物混溶的抗生素/抗生素。

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