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    • 1. 发明申请
    • Cushioned Resilient Intravaginal Urinary Incontinence Device and Method of Making Same
    • 缓冲弹性阴道内尿失禁装置及其制作方法
    • US20130211185A1
    • 2013-08-15
    • US13881838
    • 2012-06-01
    • Raymond J. Hull, JR.Rainer Armbruster
    • Raymond J. Hull, JR.Rainer Armbruster
    • B29C45/16A61F2/00
    • B29C45/1675A61F2/0022A61F2/005B29C45/14819B29C45/1676
    • A method of making an injection molded device includes the steps of (a) assembling a mold comprising a primary male mold half and a primary female mold half to define a primary mold cavity; (b) injecting a first fluid polymeric material into the primary mold cavity and permitting the first fluid polymeric material to solidify to form a device frame; (c) replacing the primary female mold half with a secondary female mold half; (d) restraining the device frame in the resulting mold cavity and injecting a second fluid polymeric material to form a first portion of an outer layer that retains the shape of the first overmold cavity; (e) replacing the primary male mold half with a secondary male mold half; and (f) injecting an additional amount of the second fluid polymeric material into the resulting cavity to form a sufficiently integral outer layer about the device frame.
    • 一种制造注射成型装置的方法包括以下步骤:(a)组装包括主阳半模和母阴半模的模具以限定主模腔; (b)将第一流体聚合物材料注入到所述主模腔中并允许所述第一流体聚合物材料固化以形成装置框架; (c)用母模半模替换主母模半部; (d)将装置框架限制在所得模腔中,并注入第二流体聚合材料以形成保持第一包覆模腔的形状的外层的第一部分; (e)用次级阳半模替换主阳半模; 和(f)将额外量的第二流体聚合物材料注入所得到的空腔中,以形成围绕设备框架的足够整体的外层。
    • 9. 发明申请
    • Cushioned Resilient Intravaginal Urinary Incontinence Device
    • 缓冲弹性阴道内尿失禁装置
    • US20120136199A1
    • 2012-05-31
    • US12956824
    • 2010-11-30
    • Mari HouRaymond J. Hull, JR.Pramod MavinkurveLeonard Rosenfeld
    • Mari HouRaymond J. Hull, JR.Pramod MavinkurveLeonard Rosenfeld
    • A61F2/04
    • A61F2/005A61F2250/0019A61F2250/0036A61F2250/0039
    • An intravaginal device has an insertion end, a withdrawal end, a longitudinal axis, and a device interior, and it includes a first structural material formed into a device frame and a second cushioning material having a thickness surrounding portions of the device frame. The first structural material includes a working portion disposed proximate the withdrawal end and an anchoring portion extending therefrom disposed proximate the insertion end. The device frame includes interconnected elongate elements having a maximum cross-section of less than about 5 mm and a longitudinal axis. The device frame has a plurality of primary bearing surfaces arranged and configured to bear on vaginal tissue during insertion and use, and the thickness of the cushioning material on the device frame is greater on the primary bearing surfaces than on surfaces of the device frame disposed toward the device interior. The device further includes a withdrawal element operatively connected to the working portion. Preferably, the first structural material is a high modulus polymer and the second material is a thermoplastic elastomer. The intravaginal device may be included in a device delivery system including a delivery applicator.
    • 阴道内装置具有插入端,抽出端,纵向轴线和装置内部,并且其包括形成装置框架的第一结构材料和具有围绕装置框架的部分的厚度的第二缓冲材料。 第一结构材料包括靠近抽出端设置的工作部分和从插入端附近设置的锚定部分。 装置框架包括具有小于约5mm的最大横截面和纵向轴线的相互连接的细长元件。 装置框架具有多个主轴承表面,其布置和构造成在插入和使用期间承载在阴道组织上,并且装置框架上的缓冲材料的厚度在主轴承表面上比在朝向 设备内部。 该装置还包括可操作地连接到工作部分的抽出元件。 优选地,第一结构材料是高模量聚合物,第二材料是热塑性弹性体。 阴道内装置可以包括在包括递送施用器的装置递送系统中。
    • 10. 发明申请
    • INTRAVAGINAL INCONTINENCE DEVICE
    • US20110152605A1
    • 2011-06-23
    • US12974378
    • 2010-12-21
    • Raymond J. Hull, JR.Bruce C. JohnsonPramod MavinkurveLeonard Rosenfeld
    • Raymond J. Hull, JR.Bruce C. JohnsonPramod MavinkurveLeonard Rosenfeld
    • A61M1/00
    • A61F2/0022
    • An intravaginal urinary incontinence device has an insertion end and an opposed withdrawal end. The device has a resilient frame including a working portion disposed proximate the withdrawal end and an anchoring portion disposed proximate the insertion end. The working portion has a resilient structure having a plurality of connected elongate elements for providing support to an associated urinary system. The anchoring portion has a plurality of connected elongate elements arranged to expand laterally within a user's vagina. The elongate elements are formed of a high modulus polymer having an elastic modulus of at least 2 or 3 GPa. Additionally, the polymer may have an Initial Stress @ 3% Strain of at least about 30 MPa, an elongation at yield of at least 3%, a Stress Ratio of at least about 0.5, and/or an Aged Stress (t=50 hrs @ 40° C.) @ 3% Strain is greater than about 35 MPa.
    • 阴道内尿失禁装置具有插入端和相对的取出端。 该装置具有弹性框架,该框架包括靠近抽出端设置的工作部分和靠近插入端设置的锚固部分。 工作部分具有弹性结构,其具有多个连接的细长元件,用于向相关的泌尿系统提供支撑。 锚定部分具有多个连接的细长元件,其布置成在使用者的阴道内横向膨胀。 细长元件由具有至少2或3GPa的弹性模量的高模量聚合物形成。 此外,聚合物可具有至少约30MPa的初始应力@ 3%应变,至少3%的屈服伸长率,至少约0.5的应力比和/或老化应力(t = 50小时) )@ 3%应变大于约35MPa。