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1. 发明申请

US20160178649A1 METHOD AND SYSTEM FOR SENSING AND DETECTING A TARGET MOLECULE 审中-公开
标题翻译：用于传感和检测目标分子的方法和系统
公开(公告)号：US20160178649A1
公开(公告)日：2016-06-23
申请号：US14885425
申请日：2015-10-16
申请人： Ranganathan Shashidhar , Yufeng Ma , James A. Kane
发明人： Ranganathan Shashidhar , Yufeng Ma , James A. Kane
IPC分类号： G01N33/74 , B01L3/00 , G01N27/02
CPC分类号： G01N33/74 , B01L3/502761 , B01L3/50857 , B01L2200/021 , B01L2200/025 , B01L2200/04 , B01L2200/0689 , B01L2200/143 , B01L2300/0627 , B01L2300/12 , B01L2300/16 , G01N27/021 , G01N33/54346 , G01N33/5438 , G01N2333/575 , G01N2600/00
摘要： Biosensors and sensing methods that overcome the disadvantages, poor chemical, physical and long-term stability, hatch to batch variability and high cost sensor of these teachings for detecting and recognizing target molecules includes a capture and release component and a sensing component. The capture release component includes a structure having molecularly imprinted polymer nanoparticles disposed on the structure, the structure being configured to receive a target fluid having the target molecules, the target molecules being captured by one of a molecularly imprinted polymer or molecularly imprinted polymer nanoparticles, and a source of a release solvent configured to release the target molecules captured by the molecularly imprinted polymer nanoparticles, the release solvent and released target molecules constituting a release solution. The sensing component includes a sensor surface having a layer of molecular imprinted polymer disposed on the sensor surface; and a sensing circuit.
摘要翻译：克服缺点，化学，物理和长期稳定性差的生物传感器和感测方法，用于检测和识别目标分子的这些教导的批量变化和高成本传感器包括捕获和释放组件和感测组件。捕获释放组分包括具有分子印迹的聚合物纳米颗粒的结构，该结构被配置成接收具有目标分子的靶流体，靶分子由分子印迹聚合物或分子印迹聚合物纳米颗粒之一捕获，以及释放溶剂的来源，其被配置为释放由分子印迹聚合物纳米颗粒俘获的靶分子，释放溶剂和释放的靶分子构成释放溶液。感测部件包括传感器表面，其具有设置在传感器表面上的分子印记聚合物层; 和感测电路。

2. 发明授权

US09891187B1 Systems and methods for ion measurements 有权
公开(公告)号：US09891187B1
公开(公告)日：2018-02-13
申请号：US14681257
申请日：2015-04-08
申请人： Ranganathan Shashidhar , Yufeng Ma , James A. Kane
发明人： Ranganathan Shashidhar , Yufeng Ma , James A. Kane
IPC分类号： G01N27/333 , G01N27/42
CPC分类号： G01N27/423
摘要： Systems that can measure small changes in ion concentrations and method of manufacturing and using those systems. The system includes a substrate, a plurality of multi-walled carbon nanotubes, each multi-walled carbon nanotube from the plurality of multi-walled carbon nanotubes having two ends and a surface extending between the two ends, one of the two ends being disposed on and operatively attached to the substrate, the other of the two ends not being disposed on the substrate, a number of organic molecules; each organic molecule bound to one multi-walled carbon nanotube, each organic molecule also having an end group with affinity for a predetermined ion(s), and a substantially nonconducting polymer deposited on a portion of each multiwalled carbon nanotube, the portion substantially not including locations on each multiwalled carbon nanotube at which each organic molecule is chelated.

3. 发明授权

US09262692B2 Methods and systems for detection and identification of concealed materials 有权
公开(公告)号：US09262692B2
公开(公告)日：2016-02-16
申请号：US13667706
申请日：2012-11-02
申请人： James A. Kane , Ranganathan Shashidhar
发明人： James A. Kane , Ranganathan Shashidhar
IPC分类号： G06K9/00 , G06K9/48 , G01N21/47 , G01N21/55 , G01V5/00
CPC分类号： G01V5/0016
摘要： Methods and systems for efficiently and accurately detecting and identifying concealed materials. The system includes an analysis subsystem configured to process a number of pixelated images, the number of pixelated images obtained by repeatedly illuminating regions with a electromagnetic radiation source from a number of electromagnetic radiation sources, each repetition performed with a different wavelength. The number of pixelated images, after processing, constitute a vector of processed data at each pixel from a number of pixels. At each pixel, the vector of processed data is compared to a predetermined vector corresponding to a predetermined material, presence of the predetermined material being determined by the comparison.

4. 发明申请

US20100178203A1 Non-Invasive Colorimetric-Based Infection Detector And Infection Detecting Bandage 有权
标题翻译：非侵入性基于比例的感染检测器和感染检测绷带
公开(公告)号：US20100178203A1
公开(公告)日：2010-07-15
申请号：US12354708
申请日：2009-01-15
申请人： James A. Kane , Melissa Ricci , Ranganathan Shashidhar
发明人： James A. Kane , Melissa Ricci , Ranganathan Shashidhar
IPC分类号： G01N21/78
CPC分类号： G01N33/528 , A61B5/0059 , A61B5/1455 , A61B5/412 , A61B5/445
摘要： A non-invasive, calorimetric infection detector is provided, comprised of a substrate, and one or more indicator compositions disposed upon or incorporated therein. These indicator compositions exhibit a persistent change color when exposed to gaseous oxides of nitrogen and acids formed therefrom, providing a means of detecting NO production in a wound, which has been found to occur at a high level at the onset of infection in a wound. In addition, a bandage is provided, comprised of the detector, as well as a porous portion, and preferably a hydrophobic barrier layer to protect the detector from contamination by water and other fluids draining from the wound. The non-invasive, calorimetric infection detector, and bandage containing same, can be utilized to provide a convenient, easily utilized colorimetric means of detecting the onset of wound infection, thereby enabling caregivers to effectively and timely treat infections.
摘要翻译：提供了一种非侵入性的量热感染检测器，其由基底和一个或多个指示剂组合物组成，所述指示剂组合物置于或并入其中。这些指示剂组合物当暴露于由其形成的氮气和酸的气体氧化物时表现出持久的变色，提供检测伤口中的NO产生的方法，其已被发现在伤口发生时感染高水平发生。此外，提供了由检测器组成的绷带，以及多孔部分，优选地是疏水阻挡层，以保护检测器免受水和从伤口排出的其它流体的污染。可以使用非侵入性，量热感染检测器和含有其的绷带来提供方便，易于使用的比色手段来检测伤口感染的发作，从而使护理人员有效和及时地治疗感染。

5. 发明授权

US09491378B2 Methods and systems for detection and identification of concealed materials 有权
标题翻译：隐藏材料的检测和识别方法和系统
公开(公告)号：US09491378B2
公开(公告)日：2016-11-08
申请号：US14246606
申请日：2014-04-07
申请人： James A. Kane , Ranganathan Shashidhar
发明人： James A. Kane , Ranganathan Shashidhar
IPC分类号： H04N5/33 , H04N5/225 , G01J3/10 , G01J3/28 , G01J3/32 , G01J3/42 , G01J3/433 , G01J3/02 , G01N21/31 , G02B27/10 , G01N21/84
CPC分类号： H04N5/332 , G01J3/0218 , G01J3/0272 , G01J3/10 , G01J3/2803 , G01J3/32 , G01J3/42 , G01J3/433 , G01N21/314 , G01N21/8422 , G01N2201/0221 , G02B27/1013 , H04N5/2256
摘要： Methods and systems for efficiently and accurately detecting and identifying concealed materials. The system includes an analysis subsystem configured to process a number of pixelated images, the number of pixelated images obtained by repeatedly illuminating, through a patterning component, regions, where an electromagnetic radiation source, from a number of electromagnetic radiation sources, illuminates the patterning component, each repetition performed with a different wavelength. A number of Global pixelated images are obtained. The number of global pixelated images, after processing, constitute a vector of processed data at each pixel from a number of pixels. At each pixel, the vector of processed data is compared to a predetermined vector corresponding to a predetermined material, presence of the predetermined material being determined by the comparison.
摘要翻译：有效和准确地检测和识别隐藏材料的方法和系统。该系统包括被配置为处理多个像素化图像的分析子系统，通过从图案形成部件反复照射来自多个电磁辐射源的电磁辐射源照射图案形成部件的区域获得的像素化图像的数量，以不同的波长进行每次重复。获得了许多全局像素化图像。在处理之后，全局像素化图像的数量构成从多个像素的每个像素处理的数据的向量。在每个像素处，将处理数据的矢量与对应于预定材料的预定矢量进行比较，通过比较确定预定材料的存在。

6. 发明申请

US20150288893A1 METHODS AND SYSTEMS FOR DETECTION AND IDENTIFICATION OF CONCEALED MATERIALS 有权
标题翻译：用于检测和识别隐蔽材料的方法和系统
公开(公告)号：US20150288893A1
公开(公告)日：2015-10-08
申请号：US14246606
申请日：2014-04-07
申请人： James A. Kane , Ranganathan Shashidhar
发明人： James A. Kane , Ranganathan Shashidhar
IPC分类号： H04N5/33 , H04N5/225
CPC分类号： H04N5/332 , G01J3/0218 , G01J3/0272 , G01J3/10 , G01J3/2803 , G01J3/32 , G01J3/42 , G01J3/433 , G01N21/314 , G01N21/8422 , G01N2201/0221 , G02B27/1013 , H04N5/2256
摘要： Methods and systems for efficiently and accurately detecting and identifying concealed materials The system includes an analysis subsystem configured to process a number of pixelated images, the number of pixelated images obtained by repeatedly illuminating, through a patterning component, regions, where an electromagnetic radiation source, from a number of electromagnetic radiation sources, illuminates the patterning component, each repetition performed with a different wavelength. A number of Global pixelated images are obtained. The number of global pixelated images, after processing, constitute a vector of processed data at each pixel from a number of pixels. At each pixel, the vector of processed data is compared to a predetermined vector corresponding to a predetermined material, presence of the predetermined material being determined by the comparison.
摘要翻译：用于有效和准确地检测和识别隐藏材料的方法和系统该系统包括被配置为处理多个像素化图像的分析子系统，通过图案形成部件反复照射获得的像素化图像的数量，其中电磁辐射源，从多个电磁辐射源照射图案化部件，每次重复以不同的波长进行。获得了许多全局像素化图像。在处理之后，全局像素化图像的数量构成从多个像素的每个像素处理的数据的向量。在每个像素处，将处理数据的矢量与对应于预定材料的预定矢量进行比较，通过比较确定预定材料的存在。

7. 发明授权

US09310512B1 Methods and systems for detection and identification of concealed materials 有权
标题翻译：隐藏材料的检测和识别方法和系统
公开(公告)号：US09310512B1
公开(公告)日：2016-04-12
申请号：US14821172
申请日：2015-08-07
申请人： James A. Kane , Ranganathan Shashidhar , Timothy Bortz
发明人： James A. Kane , Ranganathan Shashidhar , Timothy Bortz
IPC分类号： G01V3/38 , G01V3/12 , G01V8/24
CPC分类号： G01V8/00
摘要： Methods and systems for efficiently and accurately detecting and identifying concealed materials. The system includes an analysis subsystem configured to process one or more detection outputs, the detection outputs obtained by illuminating regions with a electromagnetic radiation source from the number of electromagnetic radiation sources, each electromagnetic radiation source emitting at a different wavelength, the one or more detection outputs, after processing, constituting a vector of processed data, and the analysis subsystem being also configured to compare the vector of processed data to a predetermined vector corresponding to a predetermined material, presence of the predetermined material being determined by the comparison.
摘要翻译：有效和准确地检测和识别隐藏材料的方法和系统。该系统包括：分析子系统，被配置为处理一个或多个检测输出，通过用电磁辐射源照射区域获得的检测输出，所述电磁辐射源来自电磁辐射源的数量，以不同波长发射的每个电磁辐射源，所述一个或多个检测在处理之后输出构成处理数据的向量，分析子系统还被配置为将处理数据的向量与对应于预定材料的预定向量进行比较，由比较确定预定材料的存在。

8. 发明授权

US09305237B2 Methods and systems for detection and identification of concealed materials 有权
标题翻译：隐藏材料的检测和识别方法和系统
公开(公告)号：US09305237B2
公开(公告)日：2016-04-05
申请号：US13741752
申请日：2013-01-15
申请人： James A. Kane , Ranganathan Shashidhar
发明人： James A. Kane , Ranganathan Shashidhar
IPC分类号： G06K9/00 , G06K9/46 , G01V8/00
CPC分类号： G06K9/4661 , G01V8/005
摘要： Methods and systems for efficiently and accurately detecting and identifying concealed materials. The system includes an analysis subsystem configured to process a number of pixelated images, the number of pixelated images obtained by repeatedly illuminating regions with a electromagnetic radiation source from a number of electromagnetic radiation sources, each repetition performed with a different wavelength. The number of pixelated images, after processing, constitute a vector of processed data at each pixel from a number of pixels. At each pixel, the vector of processed data is compared to a predetermined vector corresponding to a predetermined material, presence of the predetermined material being determined by the comparison.
摘要翻译：有效和准确地检测和识别隐藏材料的方法和系统。该系统包括分析子系统，被配置为处理多个像素化图像，通过用多个电磁辐射源用电磁辐射源反复照射区域获得的像素化图像的数量，每个重复使用不同的波长进行。像素化图像的数量在处理之后构成来自多个像素的每个像素处理的数据的向量。在每个像素处，将处理数据的矢量与对应于预定材料的预定矢量进行比较，通过比较确定预定材料的存在。

9. 发明申请

US20140270342A1 METHODS AND SYSTEMS FOR DETECTION AND IDENTIFICATION OF CONCEALED MATERIALS 有权
标题翻译：用于检测和识别隐蔽材料的方法和系统
公开(公告)号：US20140270342A1
公开(公告)日：2014-09-18
申请号：US13741752
申请日：2013-01-15
申请人： James A. Kane , Ranganathan Shashidhar
发明人： James A. Kane , Ranganathan Shashidhar
IPC分类号： G06K9/46 , G01N21/47 , G01N21/55
CPC分类号： G06K9/4661 , G01V8/005
摘要： Methods and systems for efficiently and accurately detecting and identifying concealed materials. The system includes an analysis subsystem configured to process a number of pixelated images, the number of pixelated images obtained by repeatedly illuminating regions with a electromagnetic radiation source from a number of electromagnetic radiation sources, each repetition performed with a different wavelength. The number of pixelated images, after processing, constitute a vector of processed data at each pixel from a number of pixels. At each pixel, the vector of processed data is compared to a predetermined vector corresponding to a predetermined material, presence of the predetermined material being determined by the comparison.
摘要翻译：有效和准确地检测和识别隐藏材料的方法和系统。该系统包括分析子系统，被配置为处理多个像素化图像，通过用多个电磁辐射源用电磁辐射源反复照射区域获得的像素化图像的数量，每个重复使用不同的波长进行。像素化图像的数量在处理之后构成来自多个像素的每个像素处理的数据的向量。在每个像素处，将处理数据的矢量与对应于预定材料的预定矢量进行比较，通过比较确定预定材料的存在。

10. 发明申请

US20130114855A1 Methods and Systems for Detection and Identification of Concealed Materials 有权
标题翻译：隐藏材料的检测和识别方法与系统
公开(公告)号：US20130114855A1
公开(公告)日：2013-05-09
申请号：US13667706
申请日：2012-11-02
申请人： James A. Kane , Ranganathan Shashidhar
发明人： James A. Kane , Ranganathan Shashidhar
IPC分类号： G06K9/48 , G01N21/55 , G01N21/47
CPC分类号： G01V5/0016
摘要： Methods and systems for efficiently and accurately detecting and identifying concealed materials. The system includes an analysis subsystem configured to process a number of pixelated images, the number of pixelated images obtained by repeatedly illuminating regions with a electromagnetic radiation source from a number of electromagnetic radiation sources, each repetition performed with a different wavelength. The number of pixelated images, after processing, constitute a vector of processed data at each pixel from a number of pixels. At each pixel, the vector of processed data is compared to a predetermined vector corresponding to a predetermined material, presence of the predetermined material being determined by the comparison.
摘要翻译：有效和准确地检测和识别隐藏材料的方法和系统。该系统包括分析子系统，被配置为处理多个像素化图像，通过用多个电磁辐射源用电磁辐射源反复照射区域获得的像素化图像的数量，每个重复使用不同的波长进行。像素化图像的数量在处理之后构成来自多个像素的每个像素处理的数据的向量。在每个像素处，将处理数据的矢量与对应于预定材料的预定矢量进行比较，通过比较确定预定材料的存在。

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