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1. 发明申请

US20050027343A1 Modified guidewire for left ventricular access lead 失效
标题翻译：修改左心室导线导丝
公开(公告)号：US20050027343A1
公开(公告)日：2005-02-03
申请号：US10730269
申请日：2003-12-09
申请人： Randy Westlund , Bruce Tockman , Randall Peterfeso , John Greenland , Mary Hinders
发明人： Randy Westlund , Bruce Tockman , Randall Peterfeso , John Greenland , Mary Hinders
IPC分类号： A61M25/09 , A61N1/05
CPC分类号： A61N1/057 , A61B2017/22035 , A61M25/09 , A61M2025/09175 , A61N2001/0578
摘要： An improved guidewire for assisting in implantation of a cardiac lead includes three sections. The most distal zone is sufficiently floppy to prevent trauma to the vessel walls through which the guidewire and lead are inserted. An intermediate zone is generally stiffer and has a cross-section less than or equal to the cross-section of the distal zone. The third zone is stiffer yet and is joined to the intermediate zone by a shoulder. The shoulder cooperates with protrusions on the lead to transfer forces between the guidewire and lead. A finishing wire having temporary locking means to lock the finishing wire to the lead is employed to remove the guide catheter without moving the lead from its desired location. Lubricious coatings are also provided to reduce friction between the lead and guidewire.
摘要翻译：用于辅助植入心脏引线的改进的导线包括三个部分。最远端的区域是足够的软盘，以防止对引导线和引线插入的血管壁的创伤。中间区通常较硬，横截面小于或等于远端区的横截面。第三区域较硬，并通过肩部连接到中间区域。肩部与导线上的突起配合，以在导丝和导线之间传递力。采用具有将精整线锁定到引线的临时锁定装置的精加工丝线来移除引导导管而不将引线从其期望的位置移动。还提供润滑涂层以减少引线和导丝之间的摩擦。

2. 发明授权

US07875018B2 Method for manipulating an adjustable shape guide catheter 失效
标题翻译：用于操纵可调整导向导管的方法
公开(公告)号：US07875018B2
公开(公告)日：2011-01-25
申请号：US11027114
申请日：2004-12-30
申请人： Bruce Tockman , Randy Westlund
发明人： Bruce Tockman , Randy Westlund
IPC分类号： A61M31/00
CPC分类号： A61M25/0041 , A61M25/0105 , A61M25/0136
摘要： A method of manipulating a catheter assembly involves providing an inner catheter member movably disposed within an outer catheter member. At least a distal end portion of the inner catheter member has a stiffness greater than that of at least a distal end portion of the outer catheter member. The distal end portion of the outer catheter member includes a deflectable distal end. The method further involves advancing the inner catheter member through the outer catheter member toward the deflectable distal end of the outer catheter member, and longitudinally displacing the distal end portion of the inner catheter member relative to the deflectable distal end of the outer catheter member to alter a shape of the deflectable distal end.
摘要翻译：操作导管组件的方法包括提供可移动地设置在外导管构件内的内导管构件。至少内导管部件的远端部分的刚度大于外导管部件的至少远端部分的刚度。外导管构件的远端部分包括可偏转的远端。该方法还包括使内部导管构件通过外部导管构件朝向外部导管构件的可偏转远端推进，并且相对于外部导管构件的可偏转远端纵向移动内部导管构件的远端部分以改变可偏转的远端的形状。

3. 发明授权

US07657324B2 Seal for use with cardiac lead 失效
标题翻译：密封用于心脏铅
公开(公告)号：US07657324B2
公开(公告)日：2010-02-02
申请号：US10617881
申请日：2003-07-14
申请人： Randy Westlund , Bruce Tockman , Gwen Crevensten , Lili Liu , Christopher M. Zerby
发明人： Randy Westlund , Bruce Tockman , Gwen Crevensten , Lili Liu , Christopher M. Zerby
IPC分类号： A61N1/05
CPC分类号： A61N1/0565 , A61N1/056 , A61N1/0573
摘要： A seal adapted for use with medical devices is provided. The medical device may be a lead having a distal tip adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead assembly in one embodiment includes an atraumatic tip. A seal is provided within the lead tip assembly, which prevents or limits further entry of fluids through the lead tip. The lead may be a left ventricular lead with a hemostasis mechanism provided therewithin.
摘要翻译：提供适于与医疗装置一起使用的密封件。医疗装置可以是具有适于植入在心脏上或周围的远端的引线，并且用于连接到用于监测或刺激心脏活动的系统。在一个实施例中的引线组件包括无创伤的尖端。在引线端头组件内提供密封件，其防止或限制流体进一步进入引线尖端。铅可以是在其中设置有止血机构的左心室导联。

4. 发明授权

US07628801B2 Coronary vein leads having an atraumatic tip and method therefor 有权
标题翻译：冠状静脉引导具有无创伤的尖端及其方法
公开(公告)号：US07628801B2
公开(公告)日：2009-12-08
申请号：US10128997
申请日：2002-04-23
申请人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61F7/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having an atraumatic tip is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and are biased toward a vessel wall by a preformed biased portion. Near the distal end, the lead has an optional tapered portion and a flexible portion, where the flexible portion is more flexible than the biased portion.
摘要翻译：具有无创尖端的引线适于植入在冠状脉管系统内或心脏周围并用于连接到信号发生器。引线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并且被预先偏置的部分偏压到血管壁。在远端附近，引线具有可选的锥形部分和柔性部分，其中柔性部分比偏置部分更柔性。

5. 发明授权

US07412290B2 Seal for use with medical device and system 失效
标题翻译：用于医疗器械和系统的密封
公开(公告)号：US07412290B2
公开(公告)日：2008-08-12
申请号：US10968305
申请日：2004-10-20
申请人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
发明人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
IPC分类号： A61N1/372
CPC分类号： A61N1/0573 , A61N1/0565
摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.
摘要翻译：适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。引线可以包括用于将电极固定到心脏组织的固定螺旋。导线组件可以替代地包括开放的管腔引线端头。在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。密封件包括可膨胀基质，例如水凝胶。当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。

6. 发明申请

US20070067008A1 Leads for pacing and/or sensing the heart from within the coronary veins 审中-公开
标题翻译：引导在冠状静脉内起搏和/或感测心脏
公开(公告)号：US20070067008A1
公开(公告)日：2007-03-22
申请号：US11600807
申请日：2006-11-16
申请人： Avram Scheiner , Ronald Heil , Peter Kelley , Bruce Tockman , Randy Westlund , Jay Warren
发明人： Avram Scheiner , Ronald Heil , Peter Kelley , Bruce Tockman , Randy Westlund , Jay Warren
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead for monitoring or stimulating cardiac activity is provided. The lead is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead body has one or more electrodes associated therewith. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and urged into intimate contact a vessel wall.
摘要翻译：提供监测或刺激心脏活动的潜在客户。引线适于植入在冠状脉管系统内部或其周围的心脏上，并用于连接到信号发生器。引线体具有与其相关联的一个或多个电极。导线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并被促使与血管壁紧密接触。

7. 发明申请

US20070049978A1 PACING AND SENSING VECTORS 有权
标题翻译：遮光和感光矢量
公开(公告)号：US20070049978A1
公开(公告)日：2007-03-01
申请号：US11554135
申请日：2006-10-30
申请人： Jeffrey Stahmann , Bruce Tockman , Randy Westlund , Rene Wentkowski , Russell Anderson
发明人： Jeffrey Stahmann , Bruce Tockman , Randy Westlund , Rene Wentkowski , Russell Anderson
IPC分类号： A61N1/00
CPC分类号： A61N1/36514 , A61N1/3622 , A61N1/365 , A61N1/368 , A61N1/3712
摘要： A method for allowing cardiac signals to be sensed and pacing pulse vectors to be delivered between two or more electrodes. In one embodiment, cardiac signals are sensed and pacing pulse vectors are delivered between least one of a first left ventricular electrode and a second left ventricular electrode. Alternatively, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrodes and a first supraventricular electrode. In addition, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrode, the first supraventricular electrode and a conductive housing. In an additional embodiment, a first right ventricular electrode is used to sense cardiac signals and provide pacing pulses with different combinations of the first and second left ventricular electrodes, the first supraventricular electrode and the housing.
摘要翻译：一种用于允许感测心脏信号的方法和用于在两个或更多个电极之间递送起搏脉冲矢量的方法。在一个实施例中，感测心脏信号，并且起搏脉冲向量在第一左心室电极和第二左心室电极中的至少一个之间递送。或者，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极和第一室上电极的不同组合之间递送。此外，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极，第一室上电极和导电壳体的不同组合之间递送。在另外的实施例中，第一右心室电极用于感测心脏信号并且提供具有第一和第二左心室电极，第一室上电极和外壳的不同组合的起搏脉冲。

8. 发明授权

US06584362B1 Leads for pacing and/or sensing the heart from within the coronary veins 有权
公开(公告)号：US06584362B1
公开(公告)日：2003-06-24
申请号：US09651340
申请日：2000-08-30
申请人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren
发明人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren
IPC分类号： A61N105
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead for monitoring or stimulating cardiac activity is provided. The lead is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead body has one or more electrodes associated therewith. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and urged into intimate contact a vessel wall. A method for implanting the lead into the coronary vasculature is also provided, the method comprising the steps of inserting a stylet into the lead, inserting the lead into the coronary sinus, advancing the lead from the coronary sinus toward the toward the left atrium and into a coronary vein, removing the stylet, and sensing and pacing the heart. Alternatively, the method comprises placing a guide catheter into the coronary sinus, threading a guide wire into the coronary veins, pushing the lead over the guide wire and into the coronary sinus or the coronary vein, and sensing and pacing the heart via the lead in its implanted site in the coronary sinus or the coronary vein.

9. 发明授权

US08150535B2 Sensor guided epicardial lead 失效
标题翻译：传感器引导心外膜导联
公开(公告)号：US08150535B2
公开(公告)日：2012-04-03
申请号：US12415736
申请日：2009-03-31
申请人： Bruce Tockman , Randy Westlund
发明人： Bruce Tockman , Randy Westlund
IPC分类号： A61N1/05
CPC分类号： A61N1/0587
摘要： Implantable cardiac monitoring and stimulation methods and devices with epicardial leads having sensor feedback. A fixed or extendable/retractable sensor may be displaceable within the lead's lumen and configured to sense the presence of an anatomical feature or physiological parameter of cardiac tissue in proximity with the lead body's distal end. The sensor may include an ultrasonic sensing element, a perfusion sensor, a photoplethysmographic sensor, or a blood oximetry sensor. Methods of determining suitability for implanting a lead involve the steps of accessing an epicardial surface of the heart, and moving the cardiac lead to an implant site at the epicardial surface. A transmitted signal is directed at the implant site. A reflected signal is received, indicative of the presence of a blood vessel at the implant site. A determination may be made to determine whether the implant site is suitable or unsuitable based on the reflected signal.
摘要翻译：可植入的心脏监测和刺激方法以及具有传感器反馈的心外膜引线的装置。固定的或可延伸的/可伸缩的传感器可以在引线的内腔中移位，并且被配置为感测心脏组织的解剖特征或生理参数在引线体的远端附近的存在。传感器可以包括超声波感测元件，灌注传感器，光电体积描记传感器或血液血氧测定传感器。确定用于植入引线的适合性的方法包括进入心脏的心外膜表面并将心脏导线移动到心外膜表面的植入部位的步骤。传输的信号指向植入部位。接收反射信号，指示在植入部位存在血管。可以基于反射信号确定植入位置是否合适或不合适。

10. 发明申请

US20100114114A1 CORONARY VEIN NAVIGATOR 审中-公开
标题翻译：冠状动脉导管
公开(公告)号：US20100114114A1
公开(公告)日：2010-05-06
申请号：US12685445
申请日：2010-01-11
申请人： Bruce Tockman , Jeffrey A. Hall , Randy Westlund
发明人： Bruce Tockman , Jeffrey A. Hall , Randy Westlund
IPC分类号： A61B17/00
CPC分类号： A61M25/0147 , A61M25/0152 , A61N2001/0585
摘要： A system and method for navigating coronary vasculature involves use of a guide catheter system which includes a guide catheter, a navigator catheter longitudinally displaceable within the guide catheter, and a deflection arrangement provided at a distal end of the navigator catheter. The guide catheter is advanced to at least a patient's coronary sinus ostium, and the navigator catheter is extended from the guide catheter to a location proximate or within an angled vein distal to the coronary sinus ostium. Using the deflection arrangement, a guide wire passing through the navigation catheter is directed into the angled vein. A lead having an open lumen is advanced over the guide wire to direct the lead to an implant site within the angled vein.
摘要翻译：用于导航冠状动脉脉管系统的系统和方法涉及使用引导导管系统，其包括引导导管，在引导导管内纵向移位的导航导管，以及设置在导航导管远端的偏转装置。引导导管前进到至少一个患者的冠状窦口，并且导管导管从引导导管延伸到远离冠状窦口的倾斜静脉附近的位置。使用偏转装置，穿过导航导管的导丝被引导到成角度的静脉中。具有开放管腔的引线在引导线上前进，以将引线引导到成角度静脉内的植入部位。

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