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1. 发明申请

US20080051705A1 BIFURCATION STENT DELIVERY CATHETER AND METHOD 审中-公开
标题翻译：分叉杆输送管和方法
公开(公告)号：US20080051705A1
公开(公告)日：2008-02-28
申请号：US11841515
申请日：2007-08-20
申请人： Randolf Von Oepen , Lorcan Coffey , Thomas Rieth , Richard Newhauser , Travis Yribarren , Bruce Wilson
发明人： Randolf Von Oepen , Lorcan Coffey , Thomas Rieth , Richard Newhauser , Travis Yribarren , Bruce Wilson
IPC分类号： A61M25/10
CPC分类号： A61F2/954 , A61F2/856 , A61F2002/30329 , A61F2220/0025
摘要： A bifurcation stent delivery catheter includes a first branch balloon, a second branch balloon adjacent the first branch. A centering balloon is optionally disposed distal of the second branch balloon. The balloons are coupled by a coupling device to a main shaft of a catheter. The coupling device allows axial forces to be transmitted from the main shaft to the balloons while allowing the balloons to rotate axially relative to the main shaft with ease. The coupling device functions as an axial rotational joint. The coupling device can have a flexible tubular member that connects the balloons to the main shaft, the tubular member having a torsional flexibility greater than that of the main shaft. The coupling device can have a tubular wall having a cut extending circumferentially around the tubular wall and protective boot covering the cut. The coupling device can have a wound member that allows the axial rotation.
摘要翻译：分叉支架输送导管包括第一分支气囊，邻近第一分支的第二分支球囊。定心球可选地设置在第二分支气囊的远侧。气囊通过联接装置耦合到导管的主轴。联接装置允许轴向力从主轴传递到气球，同时允许气囊相对于主轴容易地轴向旋转。联接装置用作轴向旋转接头。联接装置可以具有将气囊连接到主轴的柔性管状构件，该管状构件具有大于主轴的扭转灵活性。联接装置可以具有管状壁，其具有围绕管状壁周向延伸的切口和覆盖切口的保护靴。联接装置可以具有允许轴向旋转的卷绕构件。

2. 发明申请

US20070260224A1 FLEXIBLE CATHETER TIP HAVING A SHAPED HEAD 审中-公开
标题翻译：柔性导管带有形状的头
公开(公告)号：US20070260224A1
公开(公告)日：2007-11-08
申请号：US11683997
申请日：2007-03-08
申请人： Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Richard Newhauser , Travis Yribarren
发明人： Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Richard Newhauser , Travis Yribarren
IPC分类号： A61M25/16
CPC分类号： A61M25/0054 , A61M25/0053 , A61M25/0067 , A61M25/0069 , A61M25/008 , A61M25/0138 , A61M2025/1093
摘要： A catheter tip for attachment with an intravascular balloon catheter that is used within a body lumen is disclosed. The catheter tip includes a body portion having a base that is attached to the balloon catheter. The base defines a proximal end of the catheter tip. A head that is attached to the body portion defines a distal end of the catheter tip. An axial cavity, cooperatively defined by the body portion and the head, extends longitudinally from the proximal to the distal end of the catheter tip. The axial cavity receives a first guidewire along which the catheter is moved within the body lumen. An outer surface of the head is shaped in a predetermined manner to control the magnitude of deflection of a second guidewire that is often twisted about the first guidewire in the lumen so as to prevent catheter obstruction by the guidewires during catheter procedures.
摘要翻译：公开了用于与在体腔内使用的血管内气囊导管连接的导管末端。导管尖端包括具有附接到气囊导管的基部的主体部分。基部限定了导管尖端的近端。附接到主体部分的头限定导管末端的远端。由主体部分和头部协同地限定的轴向腔从导管末端的近端延伸到远端。轴向空腔容纳第一导丝，导管沿着该第一导丝在体腔内移动。头部的外表面以预定的方式成形，以控制通常在内腔中围绕第一导丝扭转的第二导丝的偏转量，以防止在导管过程期间导管阻塞导线。

3. 发明授权

US07993303B2 Stiffening support catheter and methods for using the same 有权
标题翻译：加强支撑导管及其使用方法
公开(公告)号：US07993303B2
公开(公告)日：2011-08-09
申请号：US11738384
申请日：2007-04-20
申请人： Randolf Von Oepen , Ian J. Clark , Lorcan Coffey , Thomas Rieth , Richard Newhauser , Travis Yribarren , Marc Gianotti , Bernhard Uihlein
发明人： Randolf Von Oepen , Ian J. Clark , Lorcan Coffey , Thomas Rieth , Richard Newhauser , Travis Yribarren , Marc Gianotti , Bernhard Uihlein
IPC分类号： A61M29/00
CPC分类号： A61M25/0054 , A61M25/0053 , A61M2025/0006 , A61M2025/0025 , A61M2025/0063
摘要： A support catheter that can puncture a heart septum with a guidewire without buckling and that can access difficult to reach arteries such as carotid or renal arteries from the aorta under difficult circumstances is provided. The support catheter comprises a catheter body having a proximal end, a distal end, and an interior wall surface defining a first lumen extending from the proximal end toward the distal end. A second lumen is disposed between the interior wall surface and an outer surface of the catheter body. A plurality of stiffening members is disposed around the second lumen, the plurality of stiffening members being engageable to selectively stiffen the catheter body. In another configuration, the catheter further comprises a second plurality of stiffening members disposed between the first lumen and the second lumen.
摘要翻译：提供了一种支撑导管，其可以用导线刺穿心脏隔膜而没有屈曲，并且可以在困难的情况下进入难以到达主动脉的颈动脉或肾动脉的动脉。支撑导管包括具有近端，远端和限定从近端朝向远端延伸的第一内腔的内壁表面的导管主体。第二管腔设置在内壁表面和导管主体的外表面之间。多个加强构件设置在第二内腔周围，多个加强构件可接合以选择性地加强导管主体。在另一种构造中，导管还包括设置在第一腔和第二腔之间的第二多个加强构件。

4. 发明申请

US20080027411A1 GUIDEWIRE PLACEMENT DEVICE 审中-公开
标题翻译： GUIDEWIRE放置设备
公开(公告)号：US20080027411A1
公开(公告)日：2008-01-31
申请号：US11739050
申请日：2007-04-23
申请人： Randolf Von Oepen , Lorcan Coffey , Richard Newhauser , Thomas Rieth , Travis Yribarren
发明人： Randolf Von Oepen , Lorcan Coffey , Richard Newhauser , Thomas Rieth , Travis Yribarren
IPC分类号： A61M25/09
CPC分类号： A61M25/0029 , A61M25/0071 , A61M25/01 , A61M25/0108 , A61M2025/0037 , A61M2025/0063 , A61M2025/018
摘要： This invention describes a guidewire placement device for facilitating the delivery of multiple guidewires to the branches of a tubular system. The invention also includes a method for placing guidewires in the branches of a tubular system using a device in accordance with the present invention, while mitigating guidewire entanglement. The present invention may be utilized during percutaneous treatment of vascular and non-vascular disease, and in particular to complement the use of balloon angioplasty and the deployment of balloon-expanded or self-expanding stents into a bifurcated vessel system.
摘要翻译：本发明描述了一种用于便于将多条导线输送到管状系统的分支的导丝放置装置。本发明还包括一种使用根据本发明的装置将导线布置在管状系统的分支中的方法，同时减轻导丝缠结。本发明可以在血管和非血管疾病的经皮治疗期间使用，特别是补充使用球囊血管成形术和将球囊扩张或自扩张支架部署到分叉血管系统中。

5. 发明申请

US20070270933A1 STENT HAVING CONTOURED PROXIMAL END 审中-公开
标题翻译：具有组合的替代结束
公开(公告)号：US20070270933A1
公开(公告)日：2007-11-22
申请号：US11683999
申请日：2007-03-08
申请人： Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Richard Newhauser , Travis Yribarren
发明人： Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Richard Newhauser , Travis Yribarren
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2/958 , A61F2002/821 , A61F2002/91508 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558
摘要： A contoured intraluminal stent for deployment proximate a bifurcated vessel is disclosed. The contoured stent is configured to seat within a side branch of the bifurcated vessel so as to acceptably cover a curvilinear ostium defined at the intersection of the side branch with a main branch of the vessel. A stent deployment system includes a first guidewire positioned in the vessel main branch and a second guidewire that extends through the main branch and into the vessel side branch, wherein the intersection of the branches defines an ostium having a three-dimensionally curvilinear shape. A balloon catheter is tracked along the second guidewire to a position in the side branch proximate the ostium. A contoured stent disposed about the balloon includes a proximal end that defines a curvilinear profile that at least approximately matches the curvilinear shape of the ostium when the stent is deployed in the side branch.
摘要翻译：公开了一种用于在分叉血管附近部署的成型的管腔内支架。轮廓支架被配置为位于分叉血管的侧分支内，以便可接受地覆盖在侧分支与血管的主分支的交叉处限定的曲线口。支架展开系统包括位于容器主分支中的第一导丝和延伸穿过主分支并进入血管侧分支的第二导线，其中分支的交点限定具有三维曲线形状的口。气球导管沿着第二导丝被跟踪到靠近口的侧分支中的位置。围绕气囊设置的成像支架包括限定曲线轮廓的近端，当支架部署在侧支中时，该近端至少近似匹配口的曲线形状。

6. 发明申请

US20070260217A1 SYSTEM AND METHOD FOR DELIVERING A STENT TO A BIFURCATED VESSEL 有权
标题翻译：用于将固体输送到分散的容器的系统和方法
公开(公告)号：US20070260217A1
公开(公告)日：2007-11-08
申请号：US11683995
申请日：2007-03-08
申请人： Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Richard Newhauser , Travis Yribarren
发明人： Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Richard Newhauser , Travis Yribarren
IPC分类号： A61M25/10
CPC分类号： A61F2/954 , A61F2/91 , A61F2/958 , A61F2002/821 , A61F2250/0098 , A61M25/1002
摘要： A stent delivery catheter system for accurately positioning a stent in a bifurcated vessel is disclosed. The system includes a catheter having a terminal portion and distal tip that is placed in a main branch of the vessel proximate the bifurcation. A fixed guidewire is attached to distal tip. A port is defined in the terminal portion of the catheter. The port is aligned with an ostium of a side branch of the bifurcated vessel to allow the passage of a stent delivery device, such as a balloon catheter having a stent crimped thereon, into the side branch. Radiopaque bands are positioned on opposite ends of the port. A positioning balloon is included on a surface of the catheter opposite the port and is selectively inflatable to position the radiopaque bands adjacent the side branch ostium. The radiopaque bands are referenced to place the stent proximate the side branch ostium.
摘要翻译：公开了一种用于将支架精确定位在分叉血管中的支架输送导管系统。该系统包括具有末端部分和远侧末端的导管，其被放置在靠近分叉处的血管的主分支中。固定的导丝连接到远端。端口被限定在导管的末端部分。端口与分叉血管的侧分支的口对准，以允许支架输送装置（例如具有卷曲在其上的支架的球囊导管）通入侧支。无线电波段位于端口的相对端。定位球囊包括在导管的与端口相对的表面上，并且选择性地可充气以将不透射线的带定位在侧分支口附近。参考不透射线带将支架置于侧分支口附近。

7. 发明申请

US20070213802A1 Bifurcation Stent Delivery Catheter and Method 审中-公开
标题翻译：分叉支架输送导管和方法
公开(公告)号：US20070213802A1
公开(公告)日：2007-09-13
申请号：US11683899
申请日：2007-03-08
申请人： Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Richard Newhauser , Travis Yribarren
发明人： Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Richard Newhauser , Travis Yribarren
IPC分类号： A61F2/84
CPC分类号： A61F2/95
摘要： A stent delivery system is disclosed for delivering and deploying a radially expandable stent at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft sized suitably for insertion into the body vessel, first and second inflatable members disposed adjacent the distal end of the elongated shaft and an endoprosthesis disposed about the first and second inflatable members. The delivery system further includes a tip assembly which during to advancement of the delivery system is configured as a single tip assembly, wherein prior to deployment of the expandable endoprosthesis, the tip assembly is split into a first tip and a second tip, wherein one of the tips remains in a main branch and the second tip is advanced into a side branch lumen to align the endoprosthesis prior to deployment.
摘要翻译：公开了用于在体内容器中的战略取向和位置处递送和展开径向可扩张的支架的支架输送系统。递送系统包括细长的柔性管状轴，其尺寸适于插入身体容器中，邻近细长轴的远端设置的第一和第二可膨胀构件以及围绕第一和第二可膨胀构件设置的内假体。输送系统还包括尖端组件，其在输送系统的进行期间被配置为单个尖端组件，其中在展开可膨胀内置假体之前，将尖端组件分成第一尖端和第二尖端，其中，尖端保持在主分支中，并且第二尖端前进到侧分支内腔以在部署之前对准内假体。

8. 发明申请

US20080058722A1 Stiffening Support Catheter and Methods for Using the Same 有权
标题翻译：加强支撑导管及其使用方法
公开(公告)号：US20080058722A1
公开(公告)日：2008-03-06
申请号：US11738384
申请日：2007-04-20
申请人： Randolf Von Oepen , Ian Clark , Lorcan Coffey , Thomas Reith , Richard Newhauser , Travis Yribarren , Marc Gianotti , Bernhard Uihlein
发明人： Randolf Von Oepen , Ian Clark , Lorcan Coffey , Thomas Reith , Richard Newhauser , Travis Yribarren , Marc Gianotti , Bernhard Uihlein
IPC分类号： A61M25/04 , A61M25/00 , A61M25/09
CPC分类号： A61M25/0054 , A61M25/0053 , A61M2025/0006 , A61M2025/0025 , A61M2025/0063
摘要： A support catheter that can puncture a heart septum with a guidewire without buckling and that can access difficult to reach arteries such as carotid or renal arteries from the aorta under difficult circumstances is provided. The support catheter comprises a catheter body having a proximal end, a distal end, and an interior wall surface defining a first lumen extending from the proximal end toward the distal end. A second lumen is disposed between the interior wall surface and an outer surface of the catheter body. A plurality of stiffening members is disposed around the second lumen, the plurality of stiffening members being engageable to selectively stiffen the catheter body. In another configuration, the catheter further comprises a second plurality of stiffening members disposed between the first lumen and the second lumen.
摘要翻译：提供了一种支撑导管，其可以用导线刺穿心脏隔膜而没有屈曲，并且可以在困难的情况下进入难以到达主动脉的颈动脉或肾动脉的动脉。支撑导管包括具有近端，远端和限定从近端朝向远端延伸的第一内腔的内壁表面的导管主体。第二管腔设置在内壁表面和导管主体的外表面之间。多个加强构件设置在第二内腔周围，多个加强构件可接合以选择性地加强导管主体。在另一种构造中，导管还包括设置在第一腔和第二腔之间的第二多个加强构件。

9. 发明申请

US20070016241A1 Balloon catheter 有权
标题翻译：气球导管
公开(公告)号：US20070016241A1
公开(公告)日：2007-01-18
申请号：US11474111
申请日：2006-06-23
申请人： Randolf von Oepen , Lorcan Coffey , Thomas Rieth , Travis Yribarren , Arik Zucker
发明人： Randolf von Oepen , Lorcan Coffey , Thomas Rieth , Travis Yribarren , Arik Zucker
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61F2/958 , A61M25/1002 , A61M25/1011 , A61M25/1027 , A61M25/1029 , A61M25/104 , A61M2025/018 , A61M2025/0183 , A61M2025/1045 , A61M2025/1056 , A61M2025/107 , A61M2029/025
摘要： A catheter arrangement is described that is arranged to permit a guide wire or other structure to be fed laterally from the region of an expandable working element. The catheter includes an elongate flexible tubular member and an inflatable structure carried by a distal portion of the flexible tubular member. The flexible tubular member has a guide wire lumen and at least one fluid supply lumen that is in fluid communication with the inflatable structure. The inflatable structure includes at least one, and preferably two, inflatable members (which may take the form of balloons). In the case of two inflatable members, the first and second inflatable members are radially spaced about the guide wire lumen such that at least one gap is formed between the inflatable members. With this arrangement, the distal end of a guide wire may be advanced through the guide lumen and out of a side opening such that the guide wire passes laterally between the first and second inflatable members. With such an arrangement, a guide wire passing out of the side opening in the region between the inflatable members can readily be directed into a second branch of a vessel bifurcation while the device is positioned in a first branch.
摘要翻译：描述了布置成允许导丝或其他结构从可扩张工作元件的区域横向地供给的导管装置。导管包括细长的柔性管状构件和由柔性管状构件的远侧部分承载的可膨胀结构。柔性管状构件具有导丝腔和与可充气结构流体连通的至少一个流体供应腔。可膨胀结构包括至少一个，优选两个可膨胀构件（其可以采取气球的形式）。在两个可膨胀构件的情况下，第一和第二可膨胀构件围绕导丝管腔径向隔开，使得在可膨胀构件之间形成至少一个间隙。通过这种布置，导丝的远端可以通过引导腔前进并且从侧开口排出，使得导丝横向地在第一和第二可膨胀构件之间通过。通过这样的布置，在可膨胀构件之间的区域中的侧开口中的引导线可以容易地被引导到容器分叉的第二分支中，同时装置位于第一分支中。

10. 发明授权

US08292913B2 Method of reducing rigidity of angioplasty balloon sections 有权
标题翻译：降低血管成形术气囊截面刚度的方法
公开(公告)号：US08292913B2
公开(公告)日：2012-10-23
申请号：US13152081
申请日：2011-06-02
申请人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
发明人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61M25/1034 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1086 , A61M2025/1093 , B23K2103/42 , B23K2103/50 , B29C59/165 , B29C2791/009 , B29L2031/7542 , Y10T156/1062
摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.
摘要翻译：根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。袖子附近的刚性减少，导致导管在曲折通道中的更好的机动性。

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