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1. 发明授权

US07129038B2 Method for selectively combining multiple membranes for assembly into test strips 有权
标题翻译：选择性地组合多个膜用于组装成测试条的方法
公开(公告)号：US07129038B2
公开(公告)日：2006-10-31
申请号：US10177542
申请日：2002-06-21
申请人： Ramanan Gopalan , Jon Michael Messamer , Manoj Sharma
发明人： Ramanan Gopalan , Jon Michael Messamer , Manoj Sharma
IPC分类号： C12Q1/00
CPC分类号： G01N33/558 , B01L3/5023 , G01N33/54366 , Y10S435/805 , Y10S435/97 , Y10S436/81
摘要： A method for selectively combining multiple membranes for assembly into test strips (such as visual blood glucose test strips with side-by-side membranes). The method includes first measuring a plurality of color parameters (e.g., L*, a* and b*color parameters) associated with membrane samples from at least two membrane lots. Next, response characteristics (e.g., blood glucose response levels) are simulated for a speculative test strip that includes, for purposes of the simulation, combined multiple membranes tentatively selected from the at least two membrane lots. The simulated response characteristics are based on the measured plurality of color parameters of the tentative selection of combined multiple membranes. Optionally, the simulated response characteristics can also be based on simulated color parameters of the tentative selection of combined multiple membranes. Subsequently, assembly of the at least two membrane lots into a test strip with combined membranes is contingent on acceptable simulated response characteristics. Any suitable color parameters can be employed. The method can be used to selectively combine two or more membranes based on any number of color parameters. The assembled test strips can be used to measure glucose, cholesterol, proteins, ketones, phenylalanine or enzymes in blood, urine, saliva or other biological fluid, as well as sample fluid characteristics (e.g., pH and alkalinity).
摘要翻译：选择性地组合多个膜用于组装成测试条（例如具有并排膜的视觉血糖测试条）的方法。该方法包括首先测量与来自至少两个膜批次的膜样品相关联的多个颜色参数（例如，L *，a *和b *颜色参数）。接下来，对于推测测试条来模拟响应特征（例如，血糖响应水平），其包括为了模拟的目的，暂时选自至少两个膜批次的组合的多个膜。模拟响应特性基于组合的多个膜的暂时选择的测量的多个颜色参数。任选地，模拟的响应特性也可以基于组合的多个膜的暂时选择的模拟颜色参数。随后，将至少两个膜批次组装到具有组合膜的测试条中取决于可接受的模拟响应特性。可以使用任何合适的颜色参数。该方法可用于基于任何数量的颜色参数选择性地组合两个或多个膜。组装的测试条可用于测量血液，尿液，唾液或其他生物流体中的葡萄糖，胆固醇，蛋白质，酮，苯丙氨酸或酶，以及样品流体特性（例如pH和碱度）。

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