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1. 发明申请

US20060250133A1 Combined positron emission tomography and magnetic resonance tomography unit 失效
标题翻译：组合正电子发射断层扫描和磁共振断层扫描单元
公开(公告)号：US20060250133A1
公开(公告)日：2006-11-09
申请号：US11395251
申请日：2006-04-03
申请人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Wolfgang Renz , Sebastian Schmidt , Markus Vester
发明人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Wolfgang Renz , Sebastian Schmidt , Markus Vester
IPC分类号： G06K9/00
CPC分类号： G01R33/481 , G01T1/1603
摘要： A positron emission tomography unit (PET), having a unit part assigned to an examination space and a first evaluation unit, is combined with a magnetic resonance tomography unit (MRT). The unit part of the PRT includes at least two gamma ray detector units with in each case an assigned electronics unit. The MRT includes a second evaluation unit, a gradient coil system and a high frequency antenna device formed as a stripline antenna device having at least two conductors. The high frequency antenna device is arranged nearer to the examination space than the gradient coil system with a high frequency shield between the gradient coil system and the high frequency antenna device. Each conductor of the stripline antenna device respectively includes a gamma ray detector unit with an assigned electronics unit. The conductors of the stripline antenna device are configured for the respective gamma ray detector units and their assigned electronics units as shielding covers that are caused by the high frequency antenna device and are opaque to high frequency radiation. An examination object in the examination space can be imaged by the combined positron emission tomography and magnetic resonance tomography unit.
摘要翻译：将具有分配给检查空间的单位部分和第一评估单元的正电子发射断层摄影单元（PET）与磁共振断层摄影单元（MRT）组合。 PRT的单位部分包括至少两个伽马射线检测器单元，在每种情况下都是分配的电子单元。 MRT包括第二评估单元，梯度线圈系统和形成为具有至少两个导体的带状线天线装置的高频天线装置。高频天线装置布置成比梯度线圈系统和高频天线装置之间具有高频屏蔽的梯度线圈系统更靠近检查空间。带状线天线装置的每个导体分别包括具有分配的电子单元的伽马射线检测器单元。带状线天线装置的导体被配置用于相应的伽马射线检测器单元及其分配的电子单元作为由高频天线装置引起并且对高频辐射不透明的屏蔽盖。检查空间中的检查对象可以通过组合的正电子发射断层摄影和磁共振断层摄影单元成像。

2. 发明授权

US07522952B2 Combined positron emission tomography and magnetic resonance tomography unit 有权
标题翻译：组合正电子发射断层扫描和磁共振断层扫描单元
公开(公告)号：US07522952B2
公开(公告)日：2009-04-21
申请号：US11395267
申请日：2006-04-03
申请人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Wolfgang Renz , Sebastian Schmidt , Markus Vester
发明人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Wolfgang Renz , Sebastian Schmidt , Markus Vester
IPC分类号： A61B5/055
CPC分类号： G01T1/1603 , A61B6/037 , A61B6/4417 , A61B6/5247 , G01R33/481 , G01T1/2985
摘要： A combined PET/MRI tomography unit has a PET unit with a unit part assigned to the examination space, and a first evaluation unit for evaluating the PET electric signals. The unit part has a gamma ray detector. The combined unit has an MRI unit and a second evaluation unit for evaluating MRI signals. The MRI unit has a high frequency antenna as well as a gradient coil system, the high frequency antenna device being arranged nearer to the examination space than the gradient coil system, as well as a high frequency shield arranged between the gradient coil system and the high frequency antenna device. The PET unit part is arranged between the high frequency shield and the high frequency antenna device. A shielding cover for the high frequency antenna device faces the high frequency antenna device. The shielding cover is opaque to high frequency radiation.
摘要翻译：组合的PET / MRI断层摄影单元具有分配给检查空间的单位部分的PET单元和用于评估PET电信号的第一评估单元。单位部件具有伽马射线检测器。组合单元具有用于评估MRI信号的MRI单元和第二评估单元。 MRI单元具有高频天线以及梯度线圈系统，高频天线装置布置成比梯度线圈系统更靠近检查空间，以及布置在梯度线圈系统和高电平之间的高频屏蔽频率天线装置。 PET单元部分布置在高频屏蔽和高频天线装置之间。用于高频天线装置的屏蔽罩面向高频天线装置。屏蔽罩对高频辐射是不透明的。

3. 发明授权

US07482592B2 Method for combining PET with MR perfusion and diffusion 有权
标题翻译： PET与MR灌注和扩散相结合的方法
公开(公告)号：US07482592B2
公开(公告)日：2009-01-27
申请号：US11438208
申请日：2006-05-23
申请人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Sebastian Schmidt , Markus Vester
发明人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Sebastian Schmidt , Markus Vester
IPC分类号： G01T1/166
CPC分类号： G01T1/2985 , A61B6/037 , A61B6/507 , G01R33/481 , G01T1/1603
摘要： A method for determining positron emission measurement information in the context of positron emission tomography is disclosed. The method includes using a marker substance to carry out a positron emission measurement, in a body area of a subject to be examined, to determine positron emission measurement information, and at the same time, generating images of the body area to be examined by way of a second medical method with a time resolution suitable for determining perfusion and/or diffusion information. The method further includes using the images from the second method to determine perfusion and/or diffusion information for at least a part of the measurement period, and evaluating the positron emission measurement information as a function of the perfusion and/or diffusion information.
摘要翻译：公开了一种在正电子发射断层摄影的背景下确定正电子发射测量信息的方法。该方法包括使用标记物质进行待检查对象的身体区域中的正电子发射测定，以确定正电子发射测量信息，并且同时生成要检查的身体区域的图像具有适合于确定灌注和/或扩散信息的时间分辨率的第二医疗方法。该方法还包括使用来自第二方法的图像来确定至少部分测量周期的灌注和/或扩散信息，以及作为灌注和/或扩散信息的函数来评估正电子发射测量信息。

4. 发明授权

US08805474B2 Method for recording and evaluating PET data recorded at the same time as magnetic resonance data using a combined magnetic resonance/PET apparatus, and a combined magnetic resonance/PET apparatus 有权
标题翻译：使用组合磁共振/ PET装置记录和评价与磁共振数据同时记录的PET数据的方法，以及组合磁共振/ PET装置
公开(公告)号：US08805474B2
公开(公告)日：2014-08-12
申请号：US13008956
申请日：2011-01-19
申请人： Ralf Ladebeck , Sebastian Schmidt
发明人： Ralf Ladebeck , Sebastian Schmidt
IPC分类号： A61B5/05
CPC分类号： A61B5/055 , A61B6/037 , A61B6/4417 , A61B6/5247 , G01R33/481
摘要： A method is disclosed for recording and evaluating PET data recorded at the same time as magnetic resonance data using a combined magnetic resonance/PET apparatus, wherein in the context of a pulse sequence for recording the magnetic resonance data a magnetic resonance recording facility, including at least one gradient coil and at least one high-frequency coil, is activated. In at least one embodiment, the method includes recording the PET data and assigning the recorded PET data after the recording time point to at least two data groups assigned to a predetermined operating state of the magnetic resonance recording facility; for each data group, determining a measure of similarity of the PET data contained therein to the PET data as a whole and/or to PET data of at least one further data group, whereby if the measure of similarity is below a threshold value, the PET data of the data group is rejected and/or further evaluated separately.
摘要翻译：公开了一种用于记录和评估使用组合磁共振/ PET装置的磁共振数据同时记录的PET数据的方法，其中在用于记录磁共振数据的脉冲序列的上下文中，磁共振记录设备包括在至少一个梯度线圈和至少一个高频线圈被激活。在至少一个实施例中，该方法包括记录PET数据并将记录时间点之后记录的PET数据分配给分配给磁共振记录设备的预定操作状态的至少两个数据组; 对于每个数据组，确定其中包含的PET数据与PET数据作为整体和/或至少一个另外的数据组的PET数据的相似度的度量，由此如果相似度的测量值低于阈值，则数据组的PET数据被拒绝和/或进一步评估。

5. 发明申请

US20110178387A1 Method For Recording And Evaluating PET Data Recorded At The Same Time as Magnetic Resonance Data Using A Combined Magnetic Resonance/PET Apparatus, And A Combined Magnetic Resonance/PET Apparatus 有权
标题翻译：用于记录和评估使用组合磁共振/ PET装置和组合磁共振/ PET装置的磁共振数据同时记录的PET数据的方法
公开(公告)号：US20110178387A1
公开(公告)日：2011-07-21
申请号：US13008956
申请日：2011-01-19
申请人： Ralf Ladebeck , Sebastian Schmidt
发明人： Ralf Ladebeck , Sebastian Schmidt
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , A61B6/037 , A61B6/4417 , A61B6/5247 , G01R33/481
摘要： A method is disclosed for recording and evaluating PET data recorded at the same time as magnetic resonance data using a combined magnetic resonance/PET apparatus, wherein in the context of a pulse sequence for recording the magnetic resonance data a magnetic resonance recording facility, including at least one gradient coil and at least one high-frequency coil, is activated. In at least one embodiment, the method includes recording the PET data and assigning the recorded PET data after the recording time point to at least two data groups assigned to a predetermined operating state of the magnetic resonance recording facility; for each data group, determining a measure of similarity of the PET data contained therein to the PET data as a whole and/or to PET data of at least one further data group, whereby if the measure of similarity is below a threshold value, the PET data of the data group is rejected and/or further evaluated separately.
摘要翻译：公开了一种用于记录和评估使用组合磁共振/ PET装置的磁共振数据同时记录的PET数据的方法，其中在用于记录磁共振数据的脉冲序列的上下文中，磁共振记录设备包括在至少一个梯度线圈和至少一个高频线圈被激活。在至少一个实施例中，该方法包括记录PET数据并将记录时间点之后记录的PET数据分配给分配给磁共振记录设备的预定操作状态的至少两个数据组; 对于每个数据组，确定其中包含的PET数据与PET数据作为整体和/或至少一个另外的数据组的PET数据的相似度的度量，由此如果相似度的测量值低于阈值，则数据组的PET数据被拒绝和/或进一步评估。

6. 发明申请

US20060266947A1 Method for determining positron emission measurement information in the context of positron emission tomography 有权
标题翻译：在正电子发射断层扫描的背景下确定正电子发射测量信息的方法
公开(公告)号：US20060266947A1
公开(公告)日：2006-11-30
申请号：US11438209
申请日：2006-05-23
申请人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Sebastian Schmidt , Markus Vester
发明人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Sebastian Schmidt , Markus Vester
IPC分类号： G01T1/166
CPC分类号： G01T1/2985 , A61B6/037 , G01R33/481
摘要： A method is disclosed for determining positron emission measurement information in the context of positron emission tomography. The method includes carrying out a positron emission measurement, in a body area of a subject to be examined, to record positron emission measurement information with point resolution and determining a time frame of the measurement by, at the same time, generating images of the body area to be examined with a relatively higher time resolution and with point-resolved image data, using a second imaging method. Further, a local shift of points of individual images of the second imaging method is determined, caused by movement processes of the subject to be examined, and as a function thereof, of the positron emission measurement information for at least a part of the measurement period and of the body area to be examined. Finally, the positron emission measurement information is adjusted as a function of the determined shift.
摘要翻译：公开了一种用于在正电子发射断层摄影的背景下确定正电子发射测量信息的方法。该方法包括在待检查对象的身体区域中进行正电子发射测量，以记录具有点分辨率的正电子发射测量信息，并且通过同时生成身体的图像来确定测量的时间范围使用第二成像方法以相对较高的时间分辨率和点分辨图像数据进行检查的区域。此外，由第二成像方法的各个图像的点的局部偏移由待检查对象的移动处理确定，并且作为其功能，确定至少部分测量周期的正电子发射测量信息以及要检查的身体区域。最后，调整正电子发射测量信息作为确定的位移的函数。

7. 发明授权

US07683330B2 Method for determining positron emission measurement information in the context of positron emission tomography 有权
标题翻译：在正电子发射断层扫描的背景下确定正电子发射测量信息的方法
公开(公告)号：US07683330B2
公开(公告)日：2010-03-23
申请号：US11438209
申请日：2006-05-23
申请人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Sebastian Schmidt , Markus Vester
发明人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Sebastian Schmidt , Markus Vester
IPC分类号： G01T1/166
CPC分类号： G01T1/2985 , A61B6/037 , G01R33/481
摘要： A method is disclosed for determining positron emission measurement information in the context of positron emission tomography. The method includes carrying out a positron emission measurement, in a body area of a subject to be examined, to record positron emission measurement information with point resolution and determining a time frame of the measurement by, at the same time, generating images of the body area to be examined with a relatively higher time resolution and with point-resolved image data, using a second imaging method. Further, a local shift of points of individual images of the second imaging method is determined, caused by movement processes of the subject to be examined, and as a function thereof, of the positron emission measurement information for at least a part of the measurement period and of the body area to be examined. Finally, the positron emission measurement information is adjusted as a function of the determined shift.
摘要翻译：公开了一种用于在正电子发射断层摄影的背景下确定正电子发射测量信息的方法。该方法包括在待检查对象的身体区域中进行正电子发射测量，以记录具有点分辨率的正电子发射测量信息，并且通过同时生成身体的图像来确定测量的时间范围使用第二成像方法以相对较高的时间分辨率和点分辨图像数据进行检查的区域。此外，由第二成像方法的各个图像的点的局部偏移由待检查对象的移动处理确定，并且作为其功能，确定至少部分测量周期的正电子发射测量信息以及要检查的身体区域。最后，调整正电子发射测量信息作为确定的位移的函数。

8. 发明申请

US20090043189A1 Mobile combined MRI/PET apparatus 审中-公开
标题翻译：移动联合MRI / PET装置
公开(公告)号：US20090043189A1
公开(公告)日：2009-02-12
申请号：US12222209
申请日：2008-08-05
申请人： Ralf Ladebeck , Diana Martin , Sebastian Schmidt
发明人： Ralf Ladebeck , Diana Martin , Sebastian Schmidt
IPC分类号： A61B5/05
CPC分类号： G01R33/481 , A61B6/037 , G01R33/421 , G01R33/4215 , G01R33/422 , G01T1/1603
摘要： A combined positron emission tomography/magnetic resonance imaging apparatus, in a trailer housing is disclosed, for imaging organs of an examination object in an examination space. In at least one embodiment, the positron emission tomography/magnetic resonance imaging apparatus includes a positron emission tomography apparatus with at least one radiation detector and a magnetic resonance imaging apparatus with at least one main magnetic field coil for generating a main magnetic field, at least one gradient coil for generating a magnetic gradient field, and a radio-frequency antenna device for transmitting excitation pulses and receiving magnetic resonance signals from the examination space, the radiation detector and the at least one gradient coil being arranged coaxially and at substantially the same axial height. In order to create a mobile MRI/PET apparatus which is designed as compactly as possible and, firstly, satisfies the radiation protection requirements for protecting the surroundings of the measurement apparatus to the best possible extent and, secondly, excludes interfering environmental influences on the measurement apparatus, a shielding arrangement with at least one shielding element for attenuating the main magnetic field and the gradient field and also the annihilation radiation outside the trailer housing is provided in at least one embodiment.
摘要翻译：公开了一种组合的正电子发射断层摄影/磁共振成像装置，用于在检查空间中成像检查对象的器官。在至少一个实施例中，正电子发射断层摄影/磁共振成像装置包括具有至少一个辐射检测器和磁共振成像装置的正电子发射断层摄影装置，该装置具有至少一个用于产生主磁场的主磁场线圈，至少用于产生磁梯度场的一个梯度线圈和用于从检查空间传输激励脉冲和接收磁共振信号的射频天线装置，辐射检测器和至少一个梯度线圈同轴并且基本相同的轴向高度。为了创建尽可能紧凑地设计的移动MRI / PET装置，首先满足最大限度地保护测量装置的周围的辐射防护要求，其次，排除对测量的干扰环境影响在至少一个实施例中提供了一种屏蔽装置，其具有用于衰减主磁场和梯度场的至少一个屏蔽元件以及拖车壳体外部的湮灭辐射。

9. 发明授权

US07323874B2 Combined positron emission tomography and magnetic resonance tomography unit 失效
标题翻译：组合正电子发射断层扫描和磁共振断层扫描单元
公开(公告)号：US07323874B2
公开(公告)日：2008-01-29
申请号：US11395251
申请日：2006-04-03
申请人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Wolfgang Renz , Sebastian Schmidt , Markus Vester
发明人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Wolfgang Renz , Sebastian Schmidt , Markus Vester
IPC分类号： G01V3/00
CPC分类号： G01R33/481 , G01T1/1603
摘要： A positron emission tomography unit (PET), having a unit part assigned to an examination space and a first evaluation unit, is combined with a magnetic resonance tomography unit (MRT). The unit part of the PRT includes at least two gamma ray detector units with in each case an assigned electronics unit. The MRT includes a second evaluation unit, a gradient coil system and a high frequency antenna device formed as a stripline antenna device having at least two conductors. The high frequency antenna device is arranged nearer to the examination space than the gradient coil system with a high frequency shield between the gradient coil system and the high frequency antenna device. Each conductor of the stripline antenna device respectively includes a gamma ray detector unit with an assigned electronics unit. The conductors of the stripline antenna device are configured for the respective gamma ray detector units and their assigned electronics units as shielding covers that are caused by the high frequency antenna device and are opaque to high frequency radiation. An examination object in the examination space can be imaged by the combined positron emission tomography and magnetic resonance tomography unit.
摘要翻译：将具有分配给检查空间的单位部分和第一评估单元的正电子发射断层摄影单元（PET）与磁共振断层摄影单元（MRT）组合。 PRT的单位部分包括至少两个伽马射线检测器单元，在每种情况下都是分配的电子单元。 MRT包括第二评估单元，梯度线圈系统和形成为具有至少两个导体的带状线天线装置的高频天线装置。高频天线装置布置成比梯度线圈系统和高频天线装置之间具有高频屏蔽的梯度线圈系统更靠近检查空间。带状线天线装置的每个导体分别包括具有分配的电子单元的伽马射线检测器单元。带状线天线装置的导体被配置用于相应的伽马射线检测器单元及其分配的电子单元作为由高频天线装置引起并且对高频辐射不透明的屏蔽盖。检查空间中的检查对象可以通过组合的正电子发射断层摄影和磁共振断层摄影单元成像。

10. 发明申请

US20060284096A1 Method for combining pet with MR perfusion and diffusion 有权
标题翻译：宠物与MR灌注和扩散相结合的方法
公开(公告)号：US20060284096A1
公开(公告)日：2006-12-21
申请号：US11438208
申请日：2006-05-23
申请人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Sebastian Schmidt , Markus Vester
发明人： Robert Krieg , Rainer Kuth , Ralf Ladebeck , Ralph Oppelt , Sebastian Schmidt , Markus Vester
IPC分类号： G01T1/164
CPC分类号： G01T1/2985 , A61B6/037 , A61B6/507 , G01R33/481 , G01T1/1603
摘要： A method for determining positron emission measurement information in the context of positron emission tomography is disclosed. The method includes using a marker substance to carry out a positron emission measurement, in a body area of a subject to be examined, to determine positron emission measurement information, and at the same time, generating images of the body area to be examined by way of a second medical method with a time resolution suitable for determining perfusion and/or diffusion information. The method further includes using the images from the second method to determine perfusion and/or diffusion information for at least a part of the measurement period, and evaluating the positron emission measurement information as a function of the perfusion and/or diffusion information.
摘要翻译：公开了一种在正电子发射断层摄影的背景下确定正电子发射测量信息的方法。该方法包括使用标记物质进行待检查对象的身体区域中的正电子发射测定，以确定正电子发射测量信息，并且同时生成要检查的身体区域的图像具有适合于确定灌注和/或扩散信息的时间分辨率的第二医疗方法。该方法还包括使用来自第二方法的图像来确定至少部分测量周期的灌注和/或扩散信息，以及作为灌注和/或扩散信息的函数来评估正电子发射测量信息。

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