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2. 发明申请

US20130189342A1 HETEROGENEOUS IMPLANTABLE DEVICES FOR DRUG DELIVERY 审中-公开
标题翻译：用于药物递送的异质可植入装置
公开(公告)号：US20130189342A1
公开(公告)日：2013-07-25
申请号：US13634535
申请日：2011-03-16
申请人： Rajesh A. Patel , Sunil R. Bhonsle
发明人： Rajesh A. Patel , Sunil R. Bhonsle
IPC分类号： A61K9/00 , A61K31/485
CPC分类号： A61K9/0024 , A61K9/2086 , A61K9/2886 , A61K31/198 , A61K31/4045 , A61K31/485 , A61K45/06 , A61K47/32
摘要： The present invention comprises compositions, methods and kits for delivering drugs. The invention provides an implantable device for delivery of a pharmaceutical substance to a patient, comprising a core comprising a core polymeric material optionally containing a core pharmaceutical substance, surrounded by a first layer comprising a first-layer pharmaceutical substance and a first-layer polymeric material, optionally surrounded by one or more additional layers comprising an additional pharmaceutical substance and an additional polymeric material, where the core, first, and optional additional polymeric materials may be the same or different, and where the optional core pharmaceutical substance, first-layer pharmaceutical substance, and optional additional pharmaceutical substances are the same or different. Implantation of the device allows a controlled release of drug for an extended period of time. The device may be implanted subcutaneously in an individual in need of continuous treatment with a drug.
摘要翻译：本发明包括用于递送药物的组合物，方法和试剂盒。本发明提供了一种用于将药物物质递送到患者的可植入装置，其包括芯，其包含任选地含有核心药物物质的芯聚合物材料，被包含第一层药物物质的第一层和第一层聚合物材料，任选被包含另外的药物物质和另外的聚合物材料的一个或多个另外的层包围，其中芯，第一和任选的另外的聚合物材料可以相同或不同，并且其中任选的核心药物物质，第一层药物物质和任选的另外的药物相同或不同。装置的植入允许药物长时间控制释放。该装置可以皮下植入需要用药物连续治疗的个体中。

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