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1. 发明申请

US20130066312A1 ABLATION DEVICE WITH MULTIPLE ABLATION MODES 有权
公开(公告)号：US20130066312A1
公开(公告)日：2013-03-14
申请号：US13613931
申请日：2012-09-13
申请人： Raj Subramaniam , Josef V. Koblish , Zaya Tun , Guy R. Harvey , Minhchau N. Cao , Kurt D. Sparks
发明人： Raj Subramaniam , Josef V. Koblish , Zaya Tun , Guy R. Harvey , Minhchau N. Cao , Kurt D. Sparks
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2018/00023 , A61B2018/00065 , A61B2018/00232 , A61B2018/00238 , A61B2018/00345 , A61B2018/00351 , A61B2018/00577 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00839
摘要： Devices, systems, and methods for performing ablation therapy on body tissue are disclosed. An example ablation device for treating body tissue includes an ionically conductive balloon and a radio-frequency electrode that delivers RF energy into a distal section of the balloon. The balloon is configured to transmit the RF energy in a direction distally towards a leading end of the ablation device. Multiple ablation electrodes on the device can be used for providing lesions of different size or shape.

2. 发明授权

US09125668B2 Ablation device with multiple ablation modes 有权
标题翻译：消融装置具有多种消融模式
公开(公告)号：US09125668B2
公开(公告)日：2015-09-08
申请号：US13613931
申请日：2012-09-13
申请人： Raj Subramaniam , Josef V. Koblish , Zaya Tun , Guy R. Harvey , Minhchau N. Cao , Kurt D. Sparks
发明人： Raj Subramaniam , Josef V. Koblish , Zaya Tun , Guy R. Harvey , Minhchau N. Cao , Kurt D. Sparks
IPC分类号： A61B18/18 , A61B17/20 , A61B18/14 , A61B18/00
CPC分类号： A61B18/1492 , A61B2018/00023 , A61B2018/00065 , A61B2018/00232 , A61B2018/00238 , A61B2018/00345 , A61B2018/00351 , A61B2018/00577 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00839
摘要： Devices, systems, and methods for performing ablation therapy on body tissue are disclosed. An example ablation device for treating body tissue includes an ionically conductive balloon and a radio-frequency electrode that delivers RF energy into a distal section of the balloon. The balloon is configured to transmit the RF energy in a direction distally towards a leading end of the ablation device. Multiple ablation electrodes on the device can be used for providing lesions of different size or shape.
摘要翻译：公开了用于对身体组织进行消融治疗的装置，系统和方法。用于治疗身体组织的示例性消融装置包括离子导电球囊和将RF能量递送到气囊的远端部分的射频电极。气囊被配置为在远离消融装置的前端的方向上传送RF能量。器件上的多个消融电极可用于提供不同大小或形状的病灶。

3. 发明申请

US20130066315A1 ABLATION DEVICE WITH IONICALLY CONDUCTIVE BALLOON 有权
标题翻译：具有导电性气泡的吸引装置
公开(公告)号：US20130066315A1
公开(公告)日：2013-03-14
申请号：US13616161
申请日：2012-09-14
申请人： Raj Subramaniam , Josef V. Koblish , Zaya Tun , Guy R. Harvey , Minhchau N. Cao , Kurt D. Sparks
发明人： Raj Subramaniam , Josef V. Koblish , Zaya Tun , Guy R. Harvey , Minhchau N. Cao , Kurt D. Sparks
IPC分类号： A61B18/14 , B44C1/22
CPC分类号： A61B18/1492 , A61B2018/00077 , A61B2018/0022 , A61B2018/00238
摘要： Devices, systems, and methods for performing ablation therapy on body tissue are disclosed. An example ablation device for treating body tissue includes an ionically conductive balloon and a radio-frequency electrode that delivers RF energy into a distal section of the balloon. The balloon can have a composite structure with a non-conductive section and a conductive section. A method for fabricating a semi-permeable ablation balloon using ionizing radiation and an etching process is also disclosed.
摘要翻译：公开了用于对身体组织进行消融治疗的装置，系统和方法。用于治疗身体组织的示例性消融装置包括离子导电球囊和将RF能量递送到气囊的远端部分的射频电极。球囊可以具有非导电部分和导电部分的复合结构。还公开了一种使用电离辐射和蚀刻工艺制造半透光消融球的方法。

4. 发明授权

US09603659B2 Ablation device with ionically conductive balloon 有权
公开(公告)号：US09603659B2
公开(公告)日：2017-03-28
申请号：US13616161
申请日：2012-09-14
申请人： Raj Subramaniam , Josef V. Koblish , Zaya Tun , Guy R. Harvey , Minhchau N. Cao , Kurt D. Sparks
发明人： Raj Subramaniam , Josef V. Koblish , Zaya Tun , Guy R. Harvey , Minhchau N. Cao , Kurt D. Sparks
IPC分类号： A61B18/14 , A61B18/00
CPC分类号： A61B18/1492 , A61B2018/00077 , A61B2018/0022 , A61B2018/00238
摘要： Devices, systems, and methods for performing ablation therapy on body tissue are disclosed. An example ablation device for treating body tissue includes an ionically conductive balloon and a radio-frequency electrode that delivers RF energy into a distal section of the balloon. The balloon can have a composite structure with a non-conductive section and a conductive section. A method for fabricating a semi-permeable ablation balloon using ionizing radiation and an etching process is also disclosed.

5. 发明授权

US07509175B2 Method and devices for stimulation of an organ with the use of a transectionally placed guide wire 失效
标题翻译：使用横向放置的导丝刺激器官的方法和装置
公开(公告)号：US07509175B2
公开(公告)日：2009-03-24
申请号：US11830419
申请日：2007-07-30
申请人： Kurt D. Sparks , Charles R. Brynelsen , Mir A. Imran
发明人： Kurt D. Sparks , Charles R. Brynelsen , Mir A. Imran
IPC分类号： A61N1/05
CPC分类号： A61N1/0558 , A61F5/0026 , A61N1/36007
摘要： Devices, systems and methods are provided for electrical stimulation of a body organ, particularly within the gastrointestinal tract. In preferred embodiments, the stomach is the organ within the gastrointestinal tract which is targeted for such stimulation. A guide wire or other delivery device is positioned within the body so as to transect the stomach wall. Devices and systems are then advanced over the guide wire for attachment to the stomach wall. The guide wire may be placed by endoscopic, open, laparoscopic or a modified percutaneous approach. In a modified percutaneous approach, the stomach is accessed without the use of general anesthesia by advancing a needle through the abdomen, transecting the stomach wall with the needle and advancing the guide wire through the needle. In some embodiments, particularly for use in obese patients, the modified percutaneous approach includes advancing a trocar through the tissue of the patient toward the outer surface of the organ and advancing the needle through the trocar prior to transecting the wall with the needle.
摘要翻译：设备，系统和方法用于电刺激身体器官，特别是在胃肠道内。在优选的实施方案中，胃是针对这种刺激的胃肠道内的器官。引导线或其他输送装置定位在体内以便横切胃壁。然后，装置和系统在引导线上前进以附接到胃壁。导丝可以通过内窥镜，开放式，腹腔镜或经修改的经皮方法来放置。在改进的经皮途径中，通过使针穿过腹部，用针切开胃壁并使引导线穿过针而进入胃而不使用全身麻醉。在一些实施方案中，特别是用于肥胖患者中，经修改的经皮方法包括使套针针穿过患者的组织朝向器官的外表面，并且在用针横切壁之前使针穿过套针针。

6. 发明授权

US10154871B2 Uterine therapy device and method 有权
公开(公告)号：US10154871B2
公开(公告)日：2018-12-18
申请号：US13550392
申请日：2012-07-16
申请人： Hugh R. Sharkey , Ramiro Reyes , Kurt D. Sparks
发明人： Hugh R. Sharkey , Ramiro Reyes , Kurt D. Sparks
IPC分类号： A61B18/04 , A61B17/34 , A61B17/42 , A61B18/00
摘要： A method and system of providing therapy to a patient's uterus. The system has an access tool with a lumen, the access tool being adapted to be inserted through a human cervical canal to place an opening of the lumen within a uterus when the access tool is inserted through the cervical canal; a seal disposed at a distal region of the access tool and adapted to seal the access tool against an interior cervical os; a sealing indicator adapted to provide a user with an indication that the seal has sealed the access tool with the interior cervical os; and a vapor delivery mechanism adapted to deliver condensable vapor through the access tool to the uterus, the condensable vapor being adapted to condense within the uterus.

7. 发明授权

US08221403B2 Uterine therapy device and method 有权
标题翻译：子宫疗法装置及方法
公开(公告)号：US08221403B2
公开(公告)日：2012-07-17
申请号：US12197111
申请日：2008-08-22
申请人： Hugh R. Sharkey , Ramiro Reyes , Kurt D. Sparks
发明人： Hugh R. Sharkey , Ramiro Reyes , Kurt D. Sparks
IPC分类号： A61B18/04
CPC分类号： A61B18/04 , A61B2017/3425 , A61B2017/4216 , A61B2017/4225 , A61B2018/00005 , A61B2018/00285 , A61B2018/00559 , A61B2018/048
摘要： A method and system of providing therapy to a patient's uterus. The system has an access tool with a lumen, the access tool being adapted to be inserted through a human cervical canal to place an opening of the lumen within a uterus when the access tool is inserted through the cervical canal; a seal disposed at a distal region of the access tool and adapted to seal the access tool against an interior cervical os; a sealing indicator adapted to provide a user with an indication that the seal has sealed the access tool with the interior cervical os; and a vapor delivery mechanism adapted to deliver condensable vapor through the access tool to the uterus, the condensable vapor being adapted to condense within the uterus.
摘要翻译：为患者子宫提供治疗的方法和系统。该系统具有内腔的进入工具，当进入工具插入通过子宫颈管道时，进入工具适于插入人宫颈管以将管腔的开口放置在子宫内; 设置在所述进入工具的远侧区域处并适于将所述进入工具密封抵靠内部颈部口的密封件; 密封指示器，其适于向使用者提供所述密封件已经将所述进入工具与所述内部宫颈口密封的指示; 以及适于将可冷凝蒸气通过所述进入工具输送到子宫的蒸汽递送机构，所述可冷凝蒸气适于在子宫内冷凝。

8. 发明授权

US08216217B2 Uterine therapy device and method 有权
标题翻译：子宫疗法装置及方法
公开(公告)号：US08216217B2
公开(公告)日：2012-07-10
申请号：US12197096
申请日：2008-08-22
申请人： Hugh R. Sharkey , Ramiro Reyes , Kurt D. Sparks
发明人： Hugh R. Sharkey , Ramiro Reyes , Kurt D. Sparks
IPC分类号： A61B18/04
CPC分类号： A61B18/04 , A61B2017/3425 , A61B2017/4216 , A61B2017/4225 , A61B2018/00005 , A61B2018/00285 , A61B2018/00559 , A61B2018/048
摘要： In some embodiments the method includes inserting an access tool through a cervix and a cervical canal into the uterus; placing an expansion mechanism in contact with tissue within the uterus to move uterine tissue surfaces away from an opening in an access tool lumen; delivering vapor through the vapor delivery tool into the uterus; and condensing the vapor on tissue within the uterus. The system has an access tool adapted to be inserted through a cervical canal to place an opening of an access tool lumen within a uterus; an expansion mechanism adapted to be advanced into the uterus to move uterine tissue surfaces away from the opening in the access tool lumen; and a vapor delivery mechanism adapted to deliver condensable vapor through the access tool to the uterus, the condensable vapor being adapted to condense within the uterus.
摘要翻译：在一些实施例中，该方法包括将进入工具通过子宫颈和子宫颈管插入到子宫中; 使扩张机构与子宫内的组织接触以使子宫组织表面远离入口工具内腔中的开口; 将蒸汽通过蒸气递送工具输送到子宫中; 并将蒸气冷凝在子宫内的组织上。该系统具有适于通过子宫颈管插入以将入口工具内腔的开口置于子宫内的通路工具; 适于进入子宫以使子宫组织表面远离进入工具内腔中的开口的扩张机构; 以及适于将可冷凝蒸气通过所述进入工具输送到子宫的蒸汽递送机构，所述可冷凝蒸气适于在子宫内冷凝。

9. 发明授权

US08214049B2 Gastric stimulation systems and methods utilizing a transgastric probe 有权
标题翻译：胃刺激系统和利用经胃探针的方法
公开(公告)号：US08214049B2
公开(公告)日：2012-07-03
申请号：US12176950
申请日：2008-07-21
申请人： Charles R. Brynelsen , Michael F. Wei , Kurt D. Sparks , Kenneth L. Wong , George Pool
发明人： Charles R. Brynelsen , Michael F. Wei , Kurt D. Sparks , Kenneth L. Wong , George Pool
IPC分类号： A61N1/05
CPC分类号： A61B17/0469 , A61B2017/0472 , A61B2017/0474 , A61B2017/0475 , A61N1/05 , A61N1/36007
摘要： Gastric stimulation devices, systems and methods are provided, particularly for stimulating a gastric organ having an internal cavity. Such devices and systems are typically implanted outside of the gastric organ while the environment of the internal cavity is probed and monitored by one or more sensors. The sensor information may be used to affect the stimulation signals provided to the gastric organ by the devices and systems. Such feedback integration assists in providing treatments and stimulation programs that are tailored to the needs of the individual patient.
摘要翻译：提供胃刺激装置，系统和方法，特别是用于刺激具有内腔的胃器官。这种装置和系统通常植入胃器官外部，同时内窥镜的环境被一个或多个传感器探测和监测。传感器信息可用于影响由装置和系统提供给胃器官的刺激信号。这种反馈整合有助于提供针对个体患者需求量身定制的治疗和刺激方案。

10. 发明授权

US08197470B2 Uterine therapy device and method 有权
标题翻译：子宫疗法装置及方法
公开(公告)号：US08197470B2
公开(公告)日：2012-06-12
申请号：US12197104
申请日：2008-08-22
申请人： Hugh R. Sharkey , Ramiro Reyes , Kurt D. Sparks
发明人： Hugh R. Sharkey , Ramiro Reyes , Kurt D. Sparks
IPC分类号： A61B18/18
CPC分类号： A61B18/04 , A61B2017/3425 , A61B2017/4216 , A61B2017/4225 , A61B2018/00005 , A61B2018/00285 , A61B2018/00559 , A61B2018/048
摘要： A method and system of providing therapy to a patient's uterus. The method include the following steps: inserting an access tool through a cervix and a cervical canal into the uterus; after inserting the access tool into the uterus, inserting a vapor delivery tool through an access tool lumen; delivering vapor through the vapor delivery tool into the uterus; and condensing the vapor on tissue within the uterus. The system has an access tool, the access tool being adapted to be inserted through a human cervical canal to place an opening of the access tool lumen within a uterus when the access tool is inserted through the cervical canal; and a vapor delivery mechanism, the vapor delivery mechanism having a vapor delivery tool and a vapor source, the vapor delivery tool being adapted to be inserted through the access tool to deliver condensable vapor from the vapor source to the uterus, the condensable vapor being adapted to condense within the uterus.
摘要翻译：为患者子宫提供治疗的方法和系统。该方法包括以下步骤：通过子宫颈和子宫颈管将入口工具插入子宫; 在将进入工具插入子宫之后，将蒸气输送工具插入入口工具内腔; 将蒸汽通过蒸气递送工具输送到子宫中; 并将蒸气冷凝在子宫内的组织上。所述系统具有进入工具，所述通道工具适于插入通过人宫颈管，以在所述进入工具插入通过所述子宫颈管时将所述进入工具内腔的开口放置在子宫内; 蒸气输送机构，其具有蒸气输送工具和蒸气源，所述蒸气输送工具适于插入通过进入工具以将可冷凝蒸汽从蒸气源输送到子宫，该可冷凝蒸气适于在子宫内凝结。

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