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1. 发明申请

WO0043539A3 IMMOBILIZATION OF MOLECULES ON SURFACES VIA POLYMER BRUSHES 审中-公开
标题翻译：通过聚合物刷对表面上的分子进行固定化
公开(公告)号：WO0043539A3
公开(公告)日：2000-11-30
申请号：PCT/EP0000554
申请日：2000-01-25
申请人： BIOCHIP TECHNOLOGIES GMBH , KLAPPROTH HOLGER , PRUCKER OSWALD , RUEHE JUERGEN
发明人： KLAPPROTH HOLGER , PRUCKER OSWALD , RUEHE JUERGEN
IPC分类号： G01N33/53 , B01J19/00 , C08F2/00 , C08F4/00 , C08F20/00 , C12N15/09 , C12Q1/68 , C40B40/06 , G01N33/543 , G01N33/545 , G01N33/566 , G01N37/00
CPC分类号： G01N33/54353 , B01J2219/00529 , B01J2219/00585 , B01J2219/00596 , B01J2219/00608 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00722 , C12Q1/6834 , C40B40/06 , G01N33/545
摘要： The invention relates to polyfunctional polymer monolayers (polymer brushes) comprising a multitude of polymer chains attached to a surface, with each polymer chain comprising a multitude of units carrying at least on functional group which allows the interaction of the polymer chain with a sample molecule.
摘要翻译：本发明涉及包含连接到表面的多个聚合物链的多官能聚合物单层（聚合物刷），其中每个聚合物链包含多个单元，其携带至少一个允许聚合物链与样品分子相互作用的官能团。

2. 发明专利

DE10323685A1 未知
公开(公告)号：DE10323685A1
公开(公告)日：2004-12-09
申请号：DE10323685
申请日：2003-05-22
申请人： RUEHE JUERGEN , KLAPPROTH HOLGER
发明人： RUEHE JUERGEN , KLAPPROTH HOLGER
IPC分类号： C12Q1/68 , G01N33/50 , G01N33/543

3. 发明申请

WO0210752A3 SENSOR CHIPS WITH MULTI-LAYERS OF POLYSILOXANE 审中-公开
标题翻译：具有多层的传感器芯片的聚硅氧烷
公开(公告)号：WO0210752A3
公开(公告)日：2002-10-17
申请号：PCT/EP0108545
申请日：2001-07-24
申请人： BIOCHIP TECHNOLOGIES GMBH , KLAPPROTH HOLGER , MOHRY SONJA , RUEHE JUERGEN
发明人： KLAPPROTH HOLGER , MOHRY SONJA , RUEHE JUERGEN
IPC分类号： G01N33/543 , G01N33/52
CPC分类号： G01N33/54373 , Y10T428/31663
摘要： The invention relates to sensor chips with multi-layers of polysiloxane, having improved homogeneity.
摘要翻译：本发明涉及具有改进的均匀性聚硅氧烷多层到传感器芯片。

4. 发明专利

DE502005009522D1 VERFAHREN ZUR KOVALENTEN IMMOBILISIERUNG VON BIOMOLEKÜLEN AN POLYMEREN OBERFLÄCHEN 未知
公开(公告)号：DE502005009522D1
公开(公告)日：2010-06-17
申请号：DE502005009522
申请日：2005-03-01
申请人： RUEHE JUERGEN , KLAPPROTH HOLGER
发明人： RUEHE JUERGEN , KLAPPROTH HOLGER DR
IPC分类号： G01N33/543 , C12N11/06 , C12N11/08 , C12Q1/68

5. 发明专利

AT467126T 未知
公开(公告)号：AT467126T
公开(公告)日：2010-05-15
申请号：AT05707670
申请日：2005-03-01
申请人： RUEHE JUERGEN , KLAPPROTH HOLGER DR
发明人： RUEHE JUERGEN , KLAPPROTH HOLGER
IPC分类号： G01N33/543 , C12N11/06 , C12N11/08 , C12Q1/68
摘要： The invention relates to a method for covalently immobilising probe-biomolecules on organic surfaces by means of photoreactive cross-linking agents which are used for covalently immobilising the probe-biomolecules on an organic surface. The inventive immobilising method consists in applying said probe-biomolecules and photoactive polymers and afterwards in cross-linking.

6. 发明专利

DE102004010430A1 未知
公开(公告)号：DE102004010430A1
公开(公告)日：2005-09-22
申请号：DE102004010430
申请日：2004-03-01
申请人： RUEHE JUERGEN , KLAPPROTH HOLGER
发明人： RUEHE JUERGEN , KLAPPROTH HOLGER
IPC分类号： C12N11/06 , C12N11/08 , G01N33/543 , C12Q1/68 , G01N33/50
摘要： The invention relates to a method for covalently immobilising probe-biomolecules on organic surfaces by means of photoreactive cross-linking agents which are used for covalently immobilising the probe-biomolecules on an organic surface. The inventive immobilising method consists in applying said probe-biomolecules and photoactive polymers and afterwards in cross-linking.

7. 发明申请

WO2005012896A8 CAPACITIVELY CONTROLLED FIELD EFFECT TRANSISTOR GAS SENSOR COMPRISING A HYDROPHOBIC LAYER 审中-公开
标题翻译：含有疏水层的电容控制场效应气体传感器
公开(公告)号：WO2005012896A8
公开(公告)日：2005-03-24
申请号：PCT/EP2004008309
申请日：2004-07-24
申请人： MICRONAS GMBH , UNIV ALBERT LUDWIGS FREIBURG , RUEHE JUERGEN , SAMUEL J D JEYAPRAKASH S , FRERICHS HEINZ-PETER , LEHMANN MIRKO
发明人： RUEHE JUERGEN , SAMUEL J D JEYAPRAKASH S , FRERICHS HEINZ-PETER , LEHMANN MIRKO
IPC分类号： G01N27/22 , G01N27/414
CPC分类号： G01N33/0059 , G01N27/4143
摘要： The invention relates to a gas sensor (1) comprising a substrate (2) of a first charge carrier type whereon a drain (3) and a source (4) of a second charge carrier type are arranged. A channel area (8) is formed between the drain (3) and the source (4). The gas sensor (1) also comprises a gas sensitive layer (10) comprising poles (11, 12) between which a gas induced voltage is produced according to the concentration of a gas which is in contact with the layer (10). In order to measure said voltage, a pole (12) of the gas sensitive layer (10) is capacitatively coupled to the channel area (8) by means of an air gap (14) and the other pole (11) is connected to a counter-electrode (13) having a reference potential. A hydrophobic layer (19) is arranged on the surface of the gas sensor (1) between the gas sensitive layer (10) and the channel area (8) and/or on a sensor electrode which is connected to a gate electrode arranged on the channel area (8).
摘要翻译：一种气体传感器（1）包括衬底（2）上布置的漏极（3）和第二Ladungströgertyps源（4）的第一Ladungströgertyps的。在排水管（3）和源（4）之间形成一个Kanolbereich（8）。此外，气体传感器（1）具有一个气体敏感层（10），所述磁极（11，12），在它们之间发生在Abhöngigkeit气体感应电压位于接触气体中的层（10）的浓度，以测量电压气体敏感层（10）经由Luftspolt其一个极（12）（14）被kopazitiv耦合到沟道区（8），并与连接到具有对置电极（13）的参考电势的另一极（11）。在气体传感器的Oberflöche（1）的气体敏感层（10）和沟道区（8）和/或传感器电极，它们在所述栅电极电连接在所述沟道区域（8）布置成与一个之间，布置的疏水层（19），

8. 发明申请

WO0210758A3 SURFACE-ATTACHED POLYFUNCTIONAL POLYMER NETWORKS FOR SENSOR CHIPS 审中-公开
标题翻译：表面附着的多功能聚合物网络传感器
公开(公告)号：WO0210758A3
公开(公告)日：2002-12-05
申请号：PCT/EP0108546
申请日：2001-07-24
申请人： BIOCHIP TECHNOLOGIES GMBH , RUEHE JUERGEN
发明人： RUEHE JUERGEN
IPC分类号： G01N33/53 , B01J20/26 , B01J20/291 , B01J20/32 , C07B61/00 , C07H21/00 , C08G85/00 , C12M1/00 , C12N15/09 , C12Q1/68 , C40B40/02 , C40B40/06 , C40B40/10 , C40B40/12 , C40B50/06 , G01N33/543 , G01N37/00
CPC分类号： B01J20/291 , B01J20/26 , B01J20/3204 , B01J20/3208 , B01J20/3219 , B01J20/327 , B01J20/3272 , B01J20/3278 , B01J20/3282 , B01J2219/00497 , B01J2219/00659 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , B01J2219/00731 , B01J2220/54 , C07B2200/11 , C07H21/00 , C12Q1/6837 , C40B40/06 , C40B40/10 , C40B40/12 , G01N30/482 , G01N33/5436 , G01N33/54393 , Y10T428/2991 , Y10T428/2996 , Y10T428/2998
摘要： The invention relates to polyfunctional polymer networks comprising an assembly of cross-linked poylmer subchains attached to a surface, with each polymer subchain comprising a multitude of identical or different repeating units carrying one or more functional groups which allows an interaction with a sample or probe molecule.
摘要翻译：本发明涉及多官能聚合物网络，其包括连接到表面上的交联聚合物链子的组合，每个聚合物子链包含多个相同或不同的携带一个或多个官能团的重复单元，其允许与样品或探针分子相互作用。

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