专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2003072784A1 DELTA 6-DESATURASES FROM PRIMULACEAE, EXPRESSING PLANTS AND PUFA-CONTAINING OILS 审中-公开
标题翻译：来自PRIMULACEAE的DELTA 6-脱氧核糖核酸，表达植物和含PUFA的油
公开(公告)号：WO2003072784A1
公开(公告)日：2003-09-04
申请号：PCT/EP2003/001161
申请日：2003-02-06
申请人： ROTHAMSTED EXPERIMENTAL STATION , NAPIER, Johnathan, A. , SAYANOVA, Olga
发明人： NAPIER, Johnathan, A. , SAYANOVA, Olga
IPC分类号： C12N15/53
CPC分类号： C12N9/0083 , C12N15/8247 , C12P7/6427 , C12P7/6472
摘要： The present invention relates to an improved method for the specific production of unsaturated ω-3 fatty acids and a method for the production of triglycerides having an increased content of unsaturated fatty acids, in particular ω-3 fatty acids having more than three double bonds. The invention relates to the production of a transgenic organism, preferably a transgenic plant or a transgenic microorganism, having an increased content of fatty acids, oils or lipids having Δ 6 double bonds due to the expression of a Δ 6-desaturase from Primulaceae. The invention additionally relates to expression cassettes containing a nucleic acid sequence, a vector and organisms containing at least one nucleic acid sequence or an expression cassette. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of unsaturated fatty acids and use thereof.
摘要翻译：本发明涉及用于特异性生产不饱和ω-3脂肪酸的改进方法以及生产具有增加的不饱和脂肪酸含量，特别是具有多于三个双键的ω-3脂肪酸的甘油三酸酯的方法。本发明涉及转基因生物，优选转基因植物或转基因微生物的生产，其具有增加的具有DELTA 6双键的脂肪酸，油或脂质含量，这是由于来自菜ace科的DELTA6-去饱和酶的表达。本发明还涉及含有核酸序列，载体和含有至少一个核酸序列或表达盒的生物体的表达盒。本发明还涉及具有增加的不饱和脂肪酸含量的不饱和脂肪酸和甘油三酸酯及其用途。

2. 发明申请

WO2004057001A2 NOVEL METHOD FOR THE PRODUCTION OF POLYUNSATURATED FATTY ACIDS 审中-公开
标题翻译：用于生产聚氨酯脂肪酸的新方法
公开(公告)号：WO2004057001A2
公开(公告)日：2004-07-08
申请号：PCT/EP2003/014054
申请日：2003-12-11
申请人： UNIVERSITY OF BRISTOL , NAPIER, Johnathan, A. , SAYANOVA, Olga , LAZARUS, Colin, M. , QI, Baoxiu , HEINZ, Ernst , ZANK, Thorsten , ZÄHRINGER, Ulrich
发明人： NAPIER, Johnathan, A. , SAYANOVA, Olga , LAZARUS, Colin, M. , QI, Baoxiu , HEINZ, Ernst , ZANK, Thorsten , ZÄHRINGER, Ulrich
IPC分类号： C12N15/82
CPC分类号： C12N9/0083 , C12N9/1029 , C12N15/8247 , C12P7/6427 , C12P7/6472
摘要： The present invention relates to an improved process for the specific production of poly-unsaturated omega-3 and omega-6 fatty acids and a process for the production of triglycerides having an increased content of unsaturated fatty acids, in particular omega-3 and omega-6 fatty acids having at least two double bonds and a 20 or 22 carbon atom chain length. The invention relates to the produc-tion of a transgenic organism, preferably a transgenic plant or a transgenic microorganism, hav-ing an increased content of fatty acids, oils or lipids containing C20- or C22- fatty acids with a delta-5, 7, 8, 10 double bond, respectively due to the expression of a delta-8-desaturase and a delta-9- elon-gase from organisms such as plants preferably Algae like Isochrysis galbana or Euglena gracilis. In addition the invention relates to a process for the production of poly unsaturated fatty acids such as Eicosapentaenoic, Arachidonic, Docosapentaenoic or Docosahexaenoic acid through the co- expression of a delta -8-desaturase, a delta-9-elongase and a delta-5 desaturase in organisms such as microorganisms or plants.The invention additionally relates to the use of specific nucleic acid sequences encoding for the aforementioned proteins with delta-8-desaturase-, delta-9-elongase- or delta-5-desaturase-activity, nucleic acid constructs, vectors and organisms containing said nucleic acid sequences. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of at least 1 % by weight of unsaturated fatty acids and use thereof.
摘要翻译：本发明涉及一种用于特异性生产多不饱和ω-3和ω-6脂肪酸的改进方法，以及用于生产具有增加的不饱和脂肪酸含量，特别是ω-3和ω- 具有至少两个双键和20或22个碳原子链长度的6种脂肪酸。本发明涉及转基因生物体，优选转基因植物或转基因微生物的生产，其具有增加的脂肪酸含量，含有C20-或C22-脂肪酸的脂肪酸，含有δ-5,7 ，8,10双键，分别由于来自诸如植物优选藻类如等鞭毛藻或小球藻的生物体的δ-8-去饱和酶和δ-9-脱氢酶的表达。此外，本发明涉及通过共同表达δ-8-去饱和酶，δ-9-延伸酶和δ-5的多不饱和脂肪酸如二十碳五烯酸，花生四烯酸，多糖五烯酸或二十二碳六烯酸的生产方法除微生物或植物等生物体中的去饱和酶。本发明还涉及编码上述蛋白质的具有δ-8-去饱和酶，δ-9-延伸酶或δ-5-去饱和酶活性的特异性核酸序列的使用，核酸酸构建体，载体和含有所述核酸序列的生物体。本发明还涉及不饱和脂肪酸和甘油三酸酯，其具有增加的至少1重量％的不饱和脂肪酸的含量及其用途。

3. 发明申请

WO2011006948A1 NOVEL FATTY ACID DESATURASES AND ELONGASES AND USES THEREOF 审中-公开
标题翻译：新型脂肪酸及其用途及其用途
公开(公告)号：WO2011006948A1
公开(公告)日：2011-01-20
申请号：PCT/EP2010/060178
申请日：2010-07-15
申请人： BASF PLANT SCIENCE COMPANY GMBH , BAUER, Jörg , NAPIER, Johnathan, A. , SAYANOVA, Olga
发明人： BAUER, Jörg , NAPIER, Johnathan, A. , SAYANOVA, Olga
IPC分类号： C07K14/435 , C12N15/82
CPC分类号： C12N15/8247 , C07K14/435 , C12N9/0071 , C12N9/93 , C12Y114/19 , C12Y114/19003 , C12Y114/19004 , C12Y114/19006 , C12Y602/01003
摘要： The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g. arachidonic acid (ARA), eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA).
摘要翻译：本发明提供了分离的核酸分子，其编码来自生物Emiliana huxleyi的新型脂肪酸去饱和酶和延伸酶。本发明还提供了含有去饱和酶或延伸酶核酸分子的重组表达载体，已引入表达载体的宿主细胞，以及用于大规模生产长链多不饱和脂肪酸（LCPUFA）的方法。花生四烯酸（ARA），二十碳五烯酸（EPA）或二十二碳六烯酸（DHA）。

4. 发明申请

WO2007051577A3 VERFAHREN ZUR HERSTELLUNG VON γ-LINOLENSÄURE UND/ ODER STEARIDONSÄURE IN TRANSGENEN BRASSICACEAE UND LINACEAE 审中-公开
公开(公告)号：WO2007051577A3
公开(公告)日：2007-05-10
申请号：PCT/EP2006/010408
申请日：2006-10-30
申请人： BASF PLANT SCIENCE GMBH , NAPIER, Johnathan, A. , SAYANOVA, Olga , VENEGAS CALERON, Monica
发明人： NAPIER, Johnathan, A. , SAYANOVA, Olga , VENEGAS CALERON, Monica
IPC分类号： C12N15/82 , C07K14/415
摘要： Die vorliegende Erfindung betrifft die Herstellung von γ-Linolensäure (18:3 Δ6,9,12 ) oder Stearidonsäure (18:4 Δ6,9,12,15 ) oder γ-Linolensäure (18:3 Δ6,9,12 ) und Stearidonsäure (18:4 Δ6,9,12,15 ) in transgenen Pflanzen der Familie Brassicaceae, wobei die transgenen Pflanzen mindestens 10 Gew-% Ölsäure bezogen auf den Gesamtfettsäuregehalt enthalten und durch die Aktivität der im Verfahren verwendeten Δ-6-Desaturasen einen erhöhten Gehalt an Δ-6-C 18 -Fettsäuren aufweisen. Außerdem betrifft die Erfindung neue Nukleinsäuresequenzen, die für die im Verfahren verwendeten Δ-6-Desatu rasen codieren, Genkonstrukte enthaltend diese Nukleinsäuresequenzen, einen Vektor und transgene Pflanzen enthaltend mindestens eine Nukleinsäuresequenz bzw. ein Genkonstrukt.

5. 发明申请

WO2002077213A2 NEW ELONGASE GENE AND PRODUCTION OF Δ9-POLYUNSATURATED FATTY ACIDS 审中-公开
标题翻译：新的长链酶基因和Δ9多聚脂肪酸的生产
公开(公告)号：WO2002077213A2
公开(公告)日：2002-10-03
申请号：PCT/EP2002/003418
申请日：2002-03-26
申请人： UNIVERSITY OF BRISTOL , NAPIER, Johnathan, A. , LAZARUS, Colin, M. , QI, Baoxiu , LERCHL, Jens
发明人： NAPIER, Johnathan, A. , LAZARUS, Colin, M. , QI, Baoxiu , LERCHL, Jens
IPC分类号： C12N9/00
CPC分类号： C12N15/8247 , A01K2217/05 , C12N9/1029
摘要： The invention relates to a new elongase gene having the sequence SEQ ID NO: 1 or its derivatives, to a gene construct comprising this sequence or its derivatives and to its use. The inventive nucleic acid sequence encodes a polypeptide which elongates α-linolenic acid (C¿18:3 d9, 12, 15?) by at least two carbon atoms whereas γ-linolenic acid (C ¿18:3 d6, 9, 12?) is not elongated. The invention additionally relates to vectors or organisms comprising an elongase gene having the sequence SEQ ID NO: 1 or its derivatives. The invention further relates to a process for the production of polyunsaturated fatty acids (=PUFAs) with an organism which comprises the elongase gene and which organism produces high amounts of oils and especially oils with a high content of unsaturated fatty acids. Additionally the invention relates to an oil and/or fatty acid composition with a higher content of polyunsaturated C 20 or C 22 fatty acids with at least two double bonds and/or to a triacylglycerol composition with a higher content of said polyunsaturated fatty acids.
摘要翻译：本发明涉及具有序列SEQ ID NO：1或其衍生物的新的延伸酶基因，涉及包含该序列或其衍生物的基因构建体及其用途。本发明的核酸序列编码通过至少两个碳原子延长α-亚麻酸（C> 18：3 d9,12,15 <）的多肽，而γ-亚麻酸（C> 18：3，d6,9,12，）没有伸长。本发明还涉及包含具有序列SEQ ID NO：1或其衍生物的延伸酶基因的载体或生物体。本发明还涉及用生物体生产多不饱和脂肪酸（= PUFA）的方法，所述生物体包含延伸酶基因，该生物体产生大量的油，特别是具有高含量不饱和脂肪酸的油。此外，本发明涉及具有较高含量的多不饱和C> 20或具有至少两个双键的脂肪酸的油和/或脂肪酸组合物和/或具有更高含量的所述多不饱和的三酰基甘油组合物脂肪酸。

6. 发明申请

WO2000055330A1 POLYSATURATED FATTY ACID (PUFA) ELONGASE FROM CAENORHABDITIS ELEGANS 审中-公开
标题翻译：来自CAENORHABDITIS ELEGANS的多糖脂肪酸（PUFA）ELONGASE
公开(公告)号：WO2000055330A1
公开(公告)日：2000-09-21
申请号：PCT/GB2000/001035
申请日：2000-03-20
申请人： THE UNIVERSITY OF BRISTOL , NAPIER, Johnathan, A.
发明人： NAPIER, Johnathan, A.
IPC分类号： C12N15/54
CPC分类号： C12N9/1029 , A01K2217/05 , A61K38/00
摘要： A isolated polypeptide comprising a functional long chain polyunsaturated fatty acid (PUFA) elongase.
摘要翻译：包含功能性长链多不饱和脂肪酸（PUFA）延伸酶的分离的多肽。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式