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1. 发明申请

WO2018215421A1 SENSOR SYSTEM AND METHOD FOR MANUFACTURING THEREOF 审中-公开
公开(公告)号：WO2018215421A1
公开(公告)日：2018-11-29
申请号：PCT/EP2018/063321
申请日：2018-05-22
申请人： ROCHE DIABETES CARE GMBH , F. HOFFMANN-LA ROCHE AG , ROCHE DIABETES CARE, INC.
发明人： KUBE, Oliver , WALTER, Helmut , POGGENWISCH, Alexander
IPC分类号： A61B5/145 , A61B5/00
摘要： A sensor system (110), a method of manufacturing a flexible electronics patch (114) for use in a sensor system (110) and a method of manufacturing a sensor system (110) are disclosed. The sensor system (110) comprises - at least one analyte sensor (112) configured for at least partial implementation into a body tissue of a user; - at least one flexible electronics patch (114), the flexible electronics patch (114) comprising - at least one applicator unit (134) for applying the flexible electronics patch (114) to the skin (132) of the user; and - at least one second adhesive layer (136) for adhering the flexible electronics patch (114) to the applicator unit (134) before applying the flexible electronics patch (114) to the skin (132) of the user.

2. 发明申请

WO2017037191A1 KIT FOR DETERMINING AN ANALYTE CONCENTRATION 审中-公开
标题翻译：用于确定分析浓度的试剂盒
公开(公告)号：WO2017037191A1
公开(公告)日：2017-03-09
申请号：PCT/EP2016/070645
申请日：2016-09-01
申请人： ROCHE DIABETES CARE GMBH , F. HOFFMANN-LA ROCHE AG , ROCHE DIABETES CARE, INC.
发明人： FREY, Stephan-Michael , KUBE, Oliver , HECK, Wolfgang , WALTER, Helmut
IPC分类号： A61B5/145
CPC分类号： A61B5/145 , A61B5/0002 , A61B5/0031 , A61B5/14532 , A61B5/6833 , A61B2560/0412 , A61B2562/225
摘要： A kit (110) for determining a concentration of at least one analyte in a body fluid of a user is disclosed, the kit (110) comprising: a) a sensor module (112) comprising i. at least one sensor element (114) adapted to determine the concentration of the analyte, wherein the sensor element (114) is at least partly implantable into a body tissue (174) of the user; ii. at least one control device (116) connected to the sensor element (114), wherein the control device (116) comprises at least one data collection device (120) adapted to collect measurement data acquired by using the sensor element (114), wherein the control device (116) further comprises at least one wireless near-field communication device (122) adapted to transmit measurement data, wherein the sensor module (112) comprises a sensor module mechanical interface (126); b) at least one data reader module (132) adapted to receive measurement data trans- mitted by the sensor module (112) via wireless near-field communication, wherein the data reader module (132) comprises at least one data storage device (150) and is adapted to store the measurement data; c) at least one data transmission module (134) adapted to receive measurement data transmitted by the sensor module (112) via wireless near-field communication, wherein the data transmission module (134) comprises at least one wireless farfield communication device (152), wherein the wireless far-field communication device (152) is adapted to transmit at least part of the measurement data to an external device (156) via wireless far-field communication. The data reader module (132) and the data transmission module (134) each comprise a mechanical interface (138, 140) adapted to reversibly engage the sensor module mechanical interface (126), thereby alternatively generating a fixed spatial relationship between the sensor module (112) and the data reader module (132) or the sensor module (112) and the data transmission module (134).
摘要翻译：公开了一种用于确定使用者的体液中的至少一种分析物的浓度的试剂盒（110），所述试剂盒（110）包括：a）传感器模块（112），包括i。适于确定分析物浓度的至少一个传感器元件（114），其中所述传感器元件（114）至少部分地植入使用者的身体组织（174）中; II。连接到所述传感器元件（114）的至少一个控制设备（116），其中所述控制设备（116）包括适于收集通过使用所述传感器元件（114）获取的测量数据的至少一个数据收集设备（120），其中所述控制设备（116）还包括适于传送测量数据的至少一个无线近场通信设备（122），其中所述传感器模块（112）包括传感器模块机械接口（126）; b）至少一个数据读取器模块（132），适于经由无线近场通信接收由传感器模块（112）发送的测量数据，其中数据读取器模块（132）包括至少一个数据存储设备（150）），并适于存储测量数据; c）至少一个数据传输模块（134），其适于经由无线近场通信接收由所述传感器模块（112）发送的测量数据，其中所述数据传输模块（134）包括至少一个无线远场通信设备（152），其中所述无线远场通信设备（152）适于经由无线远场通信将至少部分所述测量数据发送到外部设备（156）。数据读取器模块（132）和数据传输模块（134）各自包括适于可逆地接合传感器模块机械接口（126）的机械接口（138,140），由此交替地在传感器模块（ 112）和数据读取器模块（132）或传感器模块（112）和数据传输模块（134）。

3. 发明申请

WO2018185138A1 BODY-WEARABLE MEDICAL DEVICE 审中-公开
公开(公告)号：WO2018185138A1
公开(公告)日：2018-10-11
申请号：PCT/EP2018/058566
申请日：2018-04-04
申请人： ROCHE DIABETES CARE GMBH , F. HOFFMANN-LA ROCHE AG , ROCHE DIABETES CARE, INC.
发明人： KUBE, Oliver , WALTER, Helmut , POGGENWISCH, Alexander
IPC分类号： A61B5/145 , A61B5/00
摘要： The invention concerns a body-wearable medical device (10), such as an analyte monitoring system or a patch-mounted pump, comprising a self-adhering flexible electronics patch (12) which adheres to the skin (50) of a user and is deformable to follow the contour of the skin (50). In order to provide a flexible non-body configuration, the electronics patch (12) includes a flexible printed circuitry (14) which is applied directly on a foil substrate (16), and a user interface (17) is configured for a user control of the device (10).

4. 发明申请

WO2017037191A8 KIT FOR DETERMINING AN ANALYTE CONCENTRATION 审中-公开
标题翻译：确定分析物浓度的试剂盒
公开(公告)号：WO2017037191A8
公开(公告)日：2017-03-09
申请号：PCT/EP2016/070645
申请日：2016-09-01
申请人： ROCHE DIABETES CARE GMBH , F. HOFFMANN-LA ROCHE AG , ROCHE DIABETES CARE, INC.
发明人： FREY, Stephan-Michael , KUBE, Oliver , HECK, Wolfgang , WALTER, Helmut
IPC分类号： A61B5/145
摘要： A kit (110) for determining a concentration of at least one analyte in a body fluid of a user is disclosed, the kit (110) comprising: a) a sensor module (112) comprising i. at least one sensor element (114) adapted to determine the concentration of the analyte, wherein the sensor element (114) is at least partly implantable into a body tissue (174) of the user; ii. at least one control device (116) connected to the sensor element (114), wherein the control device (116) comprises at least one data collection device (120) adapted to collect measurement data acquired by using the sensor element (114), wherein the control device (116) further comprises at least one wireless near-field communication device (122) adapted to transmit measurement data, wherein the sensor module (112) comprises a sensor module mechanical interface (126); b) at least one data reader module (132) adapted to receive measurement data transmitted by the sensor module (112) via wireless near-field communication, wherein the data reader module (132) comprises at least one data storage device (150) and is adapted to store the measurement data; c) at least one data transmission module (134) adapted to receive measurement data transmitted by the sensor module (112) via wireless near-field communication, wherein the data transmission module (134) comprises at least one wireless far-field communication device (152), wherein the wireless far-field communication device (152) is adapted to transmit at least part of the measurement data to an external device (156) via wireless far-field communication. The data reader module (132) and the data transmission module (134) each comprise a mechanical interface (138, 140) adapted to reversibly engage the sensor module mechanical interface (126), thereby alternatively generating a fixed spatial relationship between the sensor module (112) and the data reader module (132) or the sensor module (112) and the data transmission module (134).
摘要翻译：公开了一种用于确定使用者的体液中的至少一种分析物的浓度的试剂盒（110），所述试剂盒（110）包括：a）传感器模块（112），其包括：i。至少一个适于确定分析物浓度的传感器元件（114），其中传感器元件（114）至少部分地可植入使用者的身体组织（174）中; II。至少一个连接到传感器元件（114）的控制装置（116），其中控制装置（116）包括至少一个数据收集装置（120），其适于收集通过使用传感器元件（114）获取的测量数据，其中所述控制装置（116）还包括适于传输测量数据的至少一个无线近场通信装置（122），其中所述传感器模块（112）包括传感器模块机械接口（126）; b）至少一个数据读取器模块（132），其适于经由无线近场通信接收由所述传感器模块（112）发送的测量数据，其中所述数据读取器模块（132）包括至少一个数据存储装置（150）和适于存储测量数据; c）至少一个数据传输模块（134），其适于经由无线近场通信接收由所述传感器模块（112）传输的测量数据，其中所述数据传输模块（134）包括至少一个无线远场通信设备 152），其中所述无线远场通信设备（152）适于经由无线远场通信将所述测量数据的至少一部分发送到外部设备（156）。数据读取器模块（132）和数据传输模块（134）各自包括适于可逆地接合传感器模块机械接口（126）的机械接口（138,140），由此可选地在传感器模块 112）和数据读取器模块（132）或传感器模块（112）和数据传输模块（134）。

5. 发明申请

WO2018024814A1 MEDICAL DEVICE FOR DETECTING AT LEAST ONE ANALYTE IN A BODY FLUID 审中-公开
标题翻译：用于检测身体流体中至少一种分析物的医疗设备
公开(公告)号：WO2018024814A1
公开(公告)日：2018-02-08
申请号：PCT/EP2017/069622
申请日：2017-08-03
申请人： ROCHE DIABETES CARE GMBH , F. HOFFMANN-LA ROCHE AG , ROCHE DIABETES CARE, INC.
发明人： FREY, Stephan-Michael , KUBE, Oliver , WALTER, Helmut , CORNELIUS, Klaus
IPC分类号： A61B5/145 , A61B5/15
摘要： A medical device (110) for detecting at least one analyte in a body fluid, a method of using a medical device (110) and a method for assembling a medical device are disclosed. The medical device (110) comprises: -at least one analyte sensor(122) having an insertable portion (160) adapted for at least partially being inserted into a body tissue (194) of a user, -at least one electronics unit (172), wherein the analyte sensor (122) is operably connected to the electronics unit (172), wherein the electronics unit (172) comprises at least one interconnect device(174) with at least one electronic component attached thereto; -at least one insertion cannula (114), wherein the analyte sensor (122) partially is placed inside the insertion cannula (114); -wherein the insertion cannula (114)is movable in between at least one extended position (224) and at least one retracted position (222), wherein the electronics unit (172) remains in a fixed position (225) when the insertion cannula (114) is moved from the extended position (224) to the retracted position (222) or vice versa; -wherein the analyte sensor (122) comprises at least one active portion (148) having at least one sensor electrode (208) for sensing the analyte thereon; -wherein the analyte sensor (122) further comprises at least one passive portion (152) electrically connected to the electronics unit (172) in at least one connector portion (206); -wherein the passive portion (152) provides, in between the connector portion (206) and the active portion (148), at least one reserve loop (150) configured for compensating for an insertion path during movement from the retracted position (222) into the extended position (224) or vice versa.
摘要翻译：公开了一种用于检测体液中的至少一种分析物的医疗装置（110），使用医疗装置（110）的方法以及组装医疗装置的方法。该医疗装置（110）包括： - 至少一个分析物传感器（122），其具有适于至少部分地插入使用者的身体组织（194）中的可插入部分（160）; - 至少一个电子单元），其中所述分析物传感器（122）可操作地连接到所述电子单元（172），其中所述电子单元（172）包括至少一个互连装置（174），其上连接有至少一个电子部件; - 至少一个插入套管（114），其中分析物传感器（122）部分地放置在插入套管（114）内; - 其中插入套管114可在至少一个延伸位置224和至少一个缩回位置222之间移动，其中当插入套管114位于固定位置时，电子单元172保持在固定位置225， 114）从伸出位置（224）移动到缩回位置（222），反之亦然; - 其中分析物传感器（122）包括具有用于感测其上的分析物的至少一个传感器电极（208）的至少一个有源部分（148） - 其中分析物传感器（122）还包括在至少一个连接器部分（206）中电连接至电子单元（172）的至少一个无源部分（152）; - 其中被动部分（152）在连接器部分（206）和有效部分（148）之间提供至少一个保留环（150），该保留环被配置用于在从缩回位置（222）移动期间补偿插入路径，进入延伸位置（224），反之亦然。

6. 发明申请

WO2017140763A1 BODY-MOUNTABLE DEVICE, MEDICAL SENSOR ASSEMBLY AND METHOD OF USE 审中-公开
标题翻译：身体上的装置，医疗传感器组件和使用方法
公开(公告)号：WO2017140763A1
公开(公告)日：2017-08-24
申请号：PCT/EP2017/053479
申请日：2017-02-16
申请人： ROCHE DIABETES CARE GMBH , F. HOFFMANN-LA ROCHE AG , ROCHE DIABETES CARE INC.
发明人： HARTTIG, Herbert , KUBE, Oliver
IPC分类号： A61B5/145
CPC分类号： A61B5/145
摘要： The invention concerns a body-mountable device (12) for a medical sensor assembly (10) and a method of using the same, wherein the device (12) comprises a patch (20) configured for adhesive attachment to a body (16) of a user and a mounting unit (24) arranged on the patch (20) for connecting a disposable transcutaneous sensor (14) to a reusable electronics unit (18). In order to facilitate sterile handling, the mounting unit (24) comprises an electronics compartment (26) which is closed by a sealed cover (28) for fully encasing an internal space (44) adapted for receiving the electronics unit (18), wherein the cover (28) is operable for insertion or removal of the electronics unit (18).
摘要翻译：本发明涉及一种用于医疗传感器组件（10）的可安装在身体上的装置（12）及其使用方法，其中所述装置（12）包括贴片（20），所述贴片附接到用户的身体（16）以及布置在贴片（20）上用于将一次性经皮传感器（14）连接到可再用电子单元（18）的安装单元（24）。为了便于无菌操作，安装单元（24）包括由密封盖（28）封闭的用于完全包封适于接收电子单元（18）的内部空间（44）的电子装置隔间（26），其中盖（28）可操作用于插入或移除电子单元（18）。

7. 发明申请

WO2017085305A1 SENSOR ASSEMBLY FOR DETECTING AT LEAST ONE ANALYTE IN A BODY FLUID 审中-公开
标题翻译：用于检测体液中至少一种分析物的传感器组件
公开(公告)号：WO2017085305A1
公开(公告)日：2017-05-26
申请号：PCT/EP2016/078223
申请日：2016-11-21
申请人： ROCHE DIABETES CARE GMBH , F. HOFFMANN-LA ROCHE AG , ROCHE DIABETES CARE, INC.
发明人： HARTTIG, Herbert , KUBE, Oliver , ORTH, Michael , WALTER, Helmut
IPC分类号： A61B5/145
CPC分类号： A61B5/14865 , A61B5/14532 , A61B2560/045 , A61B2560/063
摘要： Asensor assembly (256) for detecting at least one analyte in a body fluid and a method of mounting a sensor (110) for detecting at least one analyte in a body fluid to a body mount (212) attachable to a body of a user are disclosed. The sensor assembly (256) comprises: -at least one sensor (110), wherein the sensor (110) is an electrochemical sensor; -at least one body mount (212) configured for attachment to a body of a user; -at least one insertion element (236) for transferring the sensor (110) to the body mount (212); -at least one first adhesive element (248) attached to one or both of the body mount (212) or the sensor (110), configured for attaching the sensor (110) to the body mount (212); -at least one second adhesive element (250) attached to one or both of the sensor (110) or the insertion element (236), configured for releasably attaching the sensor (110) to the insertion element (236), wherein the insertion element (236) is configured to transfer the sensor (110) from an initial position, in which the sensor (110) is attached to the insertion element (236) via the second adhesive element (250), into a final position in which the sensor (110) is attached to the body mount (212) via the first adhesive element (248) and released from the insertion element (236).
摘要翻译：用于检测体液中的至少一种分析物的传感器组件（256）以及用于检测体液中的至少一种分析物到身体安装件（212）的传感器（110）的安装方法，公开了可附接到用户的身体。传感器组件（256）包括： - 至少一个传感器（110），其中传感器（110）是电化学传感器; - 至少一个主体安装件（212），其被构造成用于附接到使用者的身体; - 至少一个插入元件（236），用于将传感器（110）传送至主体安装件（212）; - 至少一个第一粘合元件（248），其被附接到所述主体安装件（212）或所述传感器（110）中的一者或两者，被配置为将所述传感器（110）附接到所述主体安装件（212）; - 至少一个附接到所述传感器（110）或所述插入元件（236）中的一者或两者的第二粘合元件（250），所述至少一个第二粘合元件被构造成用于将所述传感器（110）可释放地附接到所述插入元件（236）（236）被配置成将传感器（110）从其中传感器（110）经由第二粘合元件（250）附接到插入元件（236）的初始位置转移到最终位置，在该位置中传感器（110）经由第一粘合元件（248）附接到主体安装件（212）并且从插入元件（236）释放。

8. 发明申请

WO2018185171A1 MEDICAL SENSOR SYSTEM, IN PARTICULAR CONTINUOUS GLUCOSE MONITORING SYSTEM 审中-公开
公开(公告)号：WO2018185171A1
公开(公告)日：2018-10-11
申请号：PCT/EP2018/058623
申请日：2018-04-04
申请人： ROCHE DIABETES CARE GMBH , F. HOFFMANN-LA ROCHE AG , ROCHE DIABETES CARE, INC.
发明人： KUBE, Oliver , WALTER, Helmut , POGGENWISCH, Alexander
IPC分类号： A61B5/145 , A61B5/00 , A61B5/1495
摘要： The invention concerns a medical sensor system (10) comprising a sensor (14) implantable under the skin (18) of a user and an on-body module (12) attachable to the skin (18) in the region of the implantable sensor (14), wherein the on-body module (12) has a self-adhering flexible electronics patch (20) including a first transmitter (28) which is operable to exchange data with the implantable sensor (14) via a short-range wireless connection (30).

9. 发明申请

WO2018166963A1 AN IMPLANT NEEDLE 审中-公开
公开(公告)号：WO2018166963A1
公开(公告)日：2018-09-20
申请号：PCT/EP2018/056059
申请日：2018-03-12
申请人： ROCHE DIABETES CARE GMBH , F. HOFFMANN-LA ROCHE AG , ROCHE DIABETES CARE, INC.
发明人： FREY, Stephan-Michael , KUBE, Oliver
IPC分类号： A61B17/34 , A61B17/32
摘要： The present disclosure refers to an implant needle (1) for introducing an implant into a body of a patient, comprising a receiving portion configured to receive an implant and provided in a hollow needle main body (2), and a taper-shaped tip portion (3). The taper-shaped tip portion (3) is further comprising: a first slant surface (14a) contiguous to a first outer peripheral surface (15) of the hollow needle main body (2), wherein the first slant surface (14a) is provided as a first non-cutting edge; a second slant surface (16a) contiguous to a second outer peripheral surface (17) of the hollow needle main body (2), wherein the second slant surface (16a) is provided as a second non-cutting edge; and a pair of sharpened surfaces (9a, 9b) symmetric with respect to an edge point (10) and a longitudinal axis (13) of the needle main body (2), wherein the sharpened surfaces (9a, 9b) are both provided with a cutting edge. The first slant surface (14a) comprises a first flank (14b), and the second slant surface (16a) comprises a second flank (16b), wherein the first flank (14b) is provided at a first distance from the edge point (10) and the second flank (16b) is provided at a second distance from the edge point (10) which is different from the first distance.

10. 发明申请

WO2016016218A1 CARRIER SYSTEM FOR A MEDICAL DEVICE WORN ON THE BODY 审中-公开
标题翻译：身体上的医疗装置的运载系统
公开(公告)号：WO2016016218A1
公开(公告)日：2016-02-04
申请号：PCT/EP2015/067223
申请日：2015-07-28
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMANN-LA ROCHE AG , ROCHE DIABETES CARE INC.
发明人： KUBE, Oliver , WALTER, Helmut
IPC分类号： A61B5/00 , A61B5/145 , A61F13/02
CPC分类号： A61B5/6833 , A61B5/0476 , A61B5/14503 , A61B5/14532 , A61F13/023 , A61F2013/00412 , A61M5/14248
摘要： The invention concerns a carrier system for a medical device worn on the body comprising a flexible carrier plaster (12) which has a flat carrier layer (20) and an adhesive coating (36) thereon consisting of a pressure sensitive adhesive which adheres on the skin of a body part, and further comprising a platform (14) which is positioned on the upper side of the carrier layer (20) for mounting the device, wherein the platform (14) has a bottom joining area (34) which is joined to the upper side of the carrier layer (20) by means of a structural adhesive which is applied as a bead along predefined adherend tracks (38,40).
摘要翻译：本发明涉及一种用于穿戴在身体上的医疗装置的载体系统，包括柔性载体石膏（12），其具有平坦载体层（20）和粘合剂涂层（36），所述粘合剂涂层（36）由粘附在皮肤上的压敏粘合剂并且还包括位于所述载体层（20）的上侧上用于安装所述装置的平台（14），其中所述平台（14）具有底部接合区域（34），所述底部接合区域（34）被连接到载体层（20）的上侧通过结构粘合剂，其沿预定的粘附轨道（38,40）作为珠粒施加。

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