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1. 发明申请

WO2004020674A1 METHODS AND COMPOSITIONS FOR FUNCTIONAL UBIQUITIN ASSAYS 审中-公开
标题翻译：功能UBIQUITIN测定的方法和组合物
公开(公告)号：WO2004020674A1
公开(公告)日：2004-03-11
申请号：PCT/US2003/026843
申请日：2003-08-29
申请人： RIGEL PHARMACEUTICALS, INC. , PRAY, Todd, R. , WONG, Brian, R. , BENNETT, Mark , PARLATI, Frank
发明人： PRAY, Todd, R. , WONG, Brian, R. , BENNETT, Mark , PARLATI, Frank
IPC分类号： C12Q1/68
CPC分类号： G01N33/5064 , C12Q1/25 , G01N33/5011 , G01N33/5029 , G01N33/5047 , G01N2333/9015 , G01N2500/10
摘要： The present attention is directed to compositions and methods for performing functional assays to determine the physiological role of ubiquitin agents and ubiquitin moieties.
摘要翻译：本发明涉及用于进行功能测定以确定泛素试剂和泛素部分的生理作用的组合物和方法。

2. 发明申请

WO2002101071A3 CD43:MODULATORS OF MAST CELL DEGRANULATION 审中-公开
公开(公告)号：WO2002101071A3
公开(公告)日：2002-12-19
申请号：PCT/US2002/017418
申请日：2002-05-31
申请人： RIGEL PHARMACEUTICALS, INC. , BENNETT, Mark , HOLLAND, Sacha , ROSSI, Alex
发明人： BENNETT, Mark , HOLLAND, Sacha , ROSSI, Alex
IPC分类号： C12Q1/00
摘要： The present invention relates to regulation of IgE-receptor-mediated mast cell degranulation. More particularly, the present invention is directed to nucleic acids encoding CD43 (also called leukosialin or leukocyte large sialoglycoprotein), which is involved in modulation of IgE-receptor-mediated mast cell degranulation. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions, antibodies, siRNA, antisense nucleic acids, and ribozymes, that modulate IgE-receptor-mediated mast cell degranulation via modulation of CD43 and CD43-related signal transduction; as well as to the use of expression profiles and compositions in diagnosis and therapy related to diseases such as allergies and asthma.

3. 发明申请

WO2002101071A2 CD43:MODULATORS OF MAST CELL DEGRANULATION 审中-公开
标题翻译： CD43：MASTCELL DEGRANULATION的调节剂
公开(公告)号：WO2002101071A2
公开(公告)日：2002-12-19
申请号：PCT/US2002/017418
申请日：2002-05-31
申请人： RIGEL PHARMACEUTICALS, INC. , BENNETT, Mark , HOLLAND, Sacha , ROSSI, Alex
发明人： BENNETT, Mark , HOLLAND, Sacha , ROSSI, Alex
IPC分类号： C12Q
CPC分类号： C07K14/70596 , A61K38/00
摘要： The present invention relates to regulation of IgE-receptor-mediated mast cell degranulation. More particularly, the present invention is directed to nucleic acids encoding CD43 (also called leukosialin or leukocyte large sialoglycoprotein), which is involved in modulation of IgE-receptor-mediated mast cell degranulation. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions, antibodies, siRNA, antisense nucleic acids, and ribozymes, that modulate IgE-receptor-mediated mast cell degranulation via modulation of CD43 and CD43-related signal transduction; as well as to the use of expression profiles and compositions in diagnosis and therapy related to diseases such as allergies and asthma.
摘要翻译：本发明涉及IgE受体介导的肥大细胞脱粒的调节。更具体地，本发明涉及编码CD43（也称为白血球蛋白或白细胞大唾液酸糖蛋白）的核酸，其涉及调节IgE受体介导的肥大细胞脱粒。本发明还涉及用于鉴定和使用通过调节CD43和CD43相关信号转导调节IgE受体介导的肥大细胞脱粒的试剂，包括小分子化学组合物，抗体，siRNA，反义核酸和核酶的方法; 以及在与诸如过敏和哮喘等疾病相关的诊断和治疗中使用表达谱和组合物。

4. 发明公开

EP1534863A1 METHODS AND COMPOSITIONS FOR FUNCTIONAL UBIQUITIN ASSAYS 审中-公开
标题翻译：方法和组合物功能的泛素ASSAYS
公开(公告)号：EP1534863A1
公开(公告)日：2005-06-01
申请号：EP03791851.3
申请日：2003-08-29
申请人： Rigel Pharmaceuticals, Inc.
发明人： PRAY, Todd, R. , WONG, Brian, R. , BENNETT, Mark , PARLATI, Frank
IPC分类号： C12Q1/68
CPC分类号： G01N33/5064 , C12Q1/25 , G01N33/5011 , G01N33/5029 , G01N33/5047 , G01N2333/9015 , G01N2500/10
摘要： The present attention is directed to compositions and methods for performing functional assays to determine the physiological role of ubiquitin agents and ubiquitin moieties.

5. 发明申请

WO2013043575A1 ORAL SYRINGE PACKAGING SYSTEM FOR HOSPITAL PHARMACIES 审中-公开
标题翻译：用于医院药物的口服包装系统
公开(公告)号：WO2013043575A1
公开(公告)日：2013-03-28
申请号：PCT/US2012/055878
申请日：2012-09-18
申请人： PERAZZO, Nicholas, J. , ROSEN, Robert, A, , GROSSKOPF, John, G. , BENNETT, Mark , COHEN, Bruce, D. , CHOPPER, John, M. , NATIONAL INSTRUMENT, L.L.C.
发明人： PERAZZO, Nicholas, J. , ROSEN, Robert, A, , GROSSKOPF, John, G. , BENNETT, Mark , COHEN, Bruce, D. , CHOPPER, John, M.
IPC分类号： B65B3/04
CPC分类号： B65B3/003 , A61J7/0053 , B65B3/006 , B65B3/28 , B65B3/30 , B65B5/045 , B65B7/28 , B65B57/02 , B65B59/00 , G06F19/00 , G06F19/3462
摘要： A semi-automated system (100) suitable for use in a hospital setting for filling patient- specific liquid prescriptions from bulk medicine containers (104) into oral syringes (S) for administration on a just-in-time basis. The system enables hospital pharmacists to simplify and streamline their task, increasing the number of prescriptions that can be filled in a day, improving patient safety and care by minimizing medication errors and the consequences that ensue.
摘要翻译：一种适用于医院设置的半自动化系统（100），用于将批量药物容器（104）中的患者特异性液体处方填充到口腔注射器（S）中，以便及时进行管理。该系统使医院药剂师能够简化和简化其任务，增加一天可以填写的处方数量，通过最大限度减少药物误差和后果，改善患者的安全和护理。

6. 发明申请

WO2013001265A8 PERSONAL HEALTH DATA COLLECTION 审中-公开
公开(公告)号：WO2013001265A8
公开(公告)日：2013-01-03
申请号：PCT/GB2012/000549
申请日：2012-06-26
申请人： LEMAN MICRO DEVICES (UK) LTD , ELLIOTT, Christopher , JONES, Mark-Eric , BENNETT, Mark , NAGOGA, Mikhail
发明人： ELLIOTT, Christopher , JONES, Mark-Eric , BENNETT, Mark , NAGOGA, Mikhail
IPC分类号： A61B5/02
摘要： The present invention provides a personal hand-held monitor comprising a signal acquisition device for acquiring signals which can be used to derive a measurement of a parameter related to the health of the user, the signal acquisition device being integrated with a personal hand-held computing device. The present invention also provides a signal acquisition device adapted to be integrated with a personal hand-held computing device to produce a personal hand-held monitor as defined above.

7. 发明申请

WO2011161453A1 PENHOLDER 审中-公开
标题翻译：笔筒
公开(公告)号：WO2011161453A1
公开(公告)日：2011-12-29
申请号：PCT/GB2011/051174
申请日：2011-06-22
申请人： L BENNETT & SON LTD , BENNETT, David , BENNETT, Mark
发明人： BENNETT, David , BENNETT, Mark
IPC分类号： B43K23/04 , B43K25/02
CPC分类号： B43K23/001 , B43K23/002 , B43M99/005
摘要： A penholder comprising a base arranged to receive and removably engage a pen, a retraction device attachable to the base, a tether connectable at one end to the base and the other to a pen and a suction cup connected to the base and configured to enable the base to be removably attached to surfaces.
摘要翻译：一种笔杆，包括布置成接收和可移除地接合笔的基座，可附接到基座的缩回装置，可在一端连接到基座并且另一端连接到笔的系绳和连接到基座的吸盘，基部可拆卸地连接到表面。

8. 发明申请

WO2006003360A1 ELECTROMAGNETIC SURVEYING 审中-公开
标题翻译：电磁测量
公开(公告)号：WO2006003360A1
公开(公告)日：2006-01-12
申请号：PCT/GB2005/002129
申请日：2005-05-26
申请人： OHM LIMITED , MILNE, James , RUST, Jennifer , SYKES, Chris , BENNETT, Mark
发明人： MILNE, James , RUST, Jennifer , SYKES, Chris , BENNETT, Mark
IPC分类号： G01V3/12
CPC分类号： G01V3/083 , G01V3/12
摘要： A submersible electromagnetic (EM) field generator (5) for seafloor electromagnetic surveying comprising an AC to DC converter (18) operable to generate a DC output from an AC input and a switching module (19) operable to generate a waveform driving signal by selectively switching the DC output. The EM field generator also comprises an antenna (20) that is operable to generate an EM field in response to the waveform driving signal. This design approach of using a switched DC source allows square or rectangular wave EM signals to be generated which have sharp transition characteristics and which are substantially independent of the AC input characteristics.
摘要翻译：一种用于海底电磁测量的潜水电磁场发生器（5），包括可操作以从AC输入产生DC输出的AC-DC转换器（18）和用于通过选择性地产生波形驱动信号的开关模块（19）切换直流输出。 EM场发生器还包括可操作以响应于波形驱动信号产生EM场的天线（20）。使用开关式DC源的这种设计方法允许产生具有明显的转变特性并且基本上与AC输入特性无关的方波或矩形波EM信号。

9. 发明申请

WO2015116637A3 ORAL SYRINGE PACKAGING SYSTEM FOR HOSPITAL PHARMACIES 审中-公开
公开(公告)号：WO2015116637A3
公开(公告)日：2015-08-06
申请号：PCT/US2015/013217
申请日：2015-01-28
申请人： PERAZZO, Nicholas, J. , ROSEN, Robert, A. , GROSSKOPF, John, G., Jr. , BENNETT, Mark , CHOPPER, John, M.
发明人： PERAZZO, Nicholas, J. , ROSEN, Robert, A. , GROSSKOPF, John, G., Jr. , BENNETT, Mark , CHOPPER, John, M.
IPC分类号： B65B3/04
摘要： A semi -automated system (100) suitable for use in a hospital setting for filling patient- specific liquid medication prescriptions from balk medicine containers (104) into oral syringes (S) for administration on a just-in-time basis. The system enables hospital pharmacists to simplify and streamline their task, increasing the number of prescriptions mat can be filled in a day, improving patient safety and care by minimizing medication errors and the consequences that ensue. The present invention also includes a novel adapter cap for use in interfacing between bulk medicine containers (104) and syringes (S) having a Luer-lock fitting.

10. 发明申请

WO2014138607A1 AUTOMATED ORAL SYRINGE PACKAGING SYSTEM FOR HOSPITAL PHARMACIES 审中-公开
标题翻译：用于医院药物的自动口服包装系统
公开(公告)号：WO2014138607A1
公开(公告)日：2014-09-12
申请号：PCT/US2014/021843
申请日：2014-03-07
申请人： PERAZZO, Nicholas, J. , NATIONAL INSTRUMENT, L.L.C. , ROSEN, Robert, A. , GROSSKOPF, John, G. Jr. , BENNETT, Mark , CHOPPER, John, M.
发明人： PERAZZO, Nicholas, J. , ROSEN, Robert, A. , GROSSKOPF, John, G. Jr. , BENNETT, Mark , CHOPPER, John, M.
IPC分类号： B65B3/04
CPC分类号： B65B3/003 , A61J1/2065 , A61J1/2096 , A61J1/22 , A61J7/0053 , A61M5/1782 , B65B7/28 , B65B7/2807 , B65B59/00 , G06F19/00 , G06F19/3462
摘要： A fully-automated system (1 ) suitable for use in a hospital setting for filling patient- specific liquid prescriptions to be administered by oral syringes on a just-in-time basis. The system enables hospital pharmacists to simplify and streamline their task, increasing the number of prescriptions that can be filled in a day, improving patient safety and care by minimizing medication errors and the consequences that ensue.
摘要翻译：一种全自动化系统（1），适用于医院设置，用于填充患者特异性液体处方，以便及时配合口服注射器。该系统使医院药剂师能够简化和简化其任务，增加一天可以填写的处方数量，通过最大限度减少药物误差和后果，改善患者的安全和护理。

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