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    • 1. 发明专利
    • DETECTING METHOD FOR GAS STREAM
    • JPH08257016A
    • 1996-10-08
    • JP31567295
    • 1995-12-04
    • RESPIRONICS INC
    • ZDROJKOWSKI RONALD JESTES MARK
    • A61B5/08A61B5/087A61M16/00A61M16/06A61M16/20A62B7/00
    • PROBLEM TO BE SOLVED: To alleviate closing of an upper airway during sleeping by supplying pressure that varies against the atmosphere into the upper airway of a patient and developing the dilation muscle of the airway. SOLUTION: A treating device 10 supplies air to a patient 12 alternately at relatively low and high pressures. The treating device 10 has a pressure bottle 16 and a gaseous stream producer 14. A gaseous stream from the gaseous stream producer 14 is supplied via a delivering tube 20 to a mask 22 mounted on the patient 12. The mask 22 has an exhausting aperture 24 for exhaustion of a breathing gas. A pressure controller 26 controls pressure of the gaseous stream within the delivering tube 26, that is, within the airway of the patient 12. A flow amount converter 28 is arranged in downflow of the pressure controller 26. An output signal 29 of the flow amount converter 28 is supplied to a flow amount signal adjusting circuit 30. The circuit produces a signal in proportion to a spontaneous flow amount of a breathing gas to the patient within the delivering tube 20. The spontaneous flow amount signal 32 from the signal adjusting circuit 30 is supplied to a determining circuit 34. An output of the determining circuit 34 controls a pressure controller 26 as a driving signal 42. A pressure value of the breathing gas corresponds to natural breathing of the patient 12.
    • 3. 发明专利
    • DE69534893T2
    • 2006-09-28
    • DE69534893
    • 1995-12-04
    • RESPIRONICS INC
    • ZDROJKOWSKI RONALD JESTES MARK
    • A61B5/08A61M16/00A61B5/087A61M16/06A61M16/20A62B7/00
    • The invention relates to a method of detecting changes in the respiratory state of a patient between inspiration and expiration. The method is of use in the control of obstructive sleep apnea using apparatus for administering a continuous positive airway pressure (CPAP) to the patient, and involves the continuous monitoring of the respiratory gas flow of the patient. From the monitoring, a respiratory gas flow characteristic is determined repeatedly at selected time intervals. Pairs of gas flow characteristics are determined at each selected time. One of each pair is the patient's actual respiratory gas flow rate at the selected time. The other is a prediction of the patient's gas flow rate at that selected time, obtained for example from the actual patient respiratory flow rate obtained at an earlier time. The characteristics of each pair are compared, and from the comparison changes in the patient's respiratory state between inspiration and expiration are identified.
    • 5. 发明专利
    • DE69535564D1
    • 2007-09-27
    • DE69535564
    • 1995-12-04
    • RESPIRONICS INC
    • ZDROJKOWSKI RONALD JESTES MARK
    • A61B5/08A61M16/00A61B5/087A61M16/06A61M16/20A62B7/00
    • The invention relates to a method of detecting changes in the respiratory state of a patient between inspiration and expiration. The method is of use in the control of obstructive sleep apnea using apparatus for administering a continuous positive airway pressure (CPAP) to the patient, and involves the continuous monitoring of the respiratory gas flow of the patient. From the monitoring, a respiratory gas flow characteristic is determined repeatedly at selected time intervals. Pairs of gas flow characteristics are determined at each selected time. One of each pair is the patient's actual respiratory gas flow rate at the selected time. The other is a prediction of the patient's gas flow rate at that selected time, obtained for example from the actual patient respiratory flow rate obtained at an earlier time. The characteristics of each pair are compared, and from the comparison changes in the patient's respiratory state between inspiration and expiration are identified.
    • 8. 发明专利
    • DE69535791D1
    • 2008-09-04
    • DE69535791
    • 1995-12-04
    • RESPIRONICS INC
    • ZDROJKOWSKI RONALD JESTES MARK
    • A61B5/08A61M16/00A61B5/087A61M16/06A61M16/20A62B7/00
    • The invention relates to a method of detecting changes in the respiratory state of a patient between inspiration and expiration. The method is of use in the control of obstructive sleep apnea using apparatus for administering a continuous positive airway pressure (CPAP) to the patient, and involves the continuous monitoring of the respiratory gas flow of the patient. From the monitoring, a respiratory gas flow characteristic is determined repeatedly at selected time intervals. Pairs of gas flow characteristics are determined at each selected time. One of each pair is the patient's actual respiratory gas flow rate at the selected time. The other is a prediction of the patient's gas flow rate at that selected time, obtained for example from the actual patient respiratory flow rate obtained at an earlier time. The characteristics of each pair are compared, and from the comparison changes in the patient's respiratory state between inspiration and expiration are identified.
    • 9. 发明专利
    • DE69535564T2
    • 2008-05-15
    • DE69535564
    • 1995-12-04
    • RESPIRONICS INC
    • ZDROJKOWSKI RONALD JESTES MARK
    • A61B5/08A61M16/00A61B5/087A61M16/06A61M16/20A62B7/00
    • The invention relates to a method of detecting changes in the respiratory state of a patient between inspiration and expiration. The method is of use in the control of obstructive sleep apnea using apparatus for administering a continuous positive airway pressure (CPAP) to the patient, and involves the continuous monitoring of the respiratory gas flow of the patient. From the monitoring, a respiratory gas flow characteristic is determined repeatedly at selected time intervals. Pairs of gas flow characteristics are determined at each selected time. One of each pair is the patient's actual respiratory gas flow rate at the selected time. The other is a prediction of the patient's gas flow rate at that selected time, obtained for example from the actual patient respiratory flow rate obtained at an earlier time. The characteristics of each pair are compared, and from the comparison changes in the patient's respiratory state between inspiration and expiration are identified.
    • 10. 发明专利
    • APARATO PARA SUMINISTRAR GAS DE RESPIRACION.
    • ES2291170T3
    • 2008-03-01
    • ES00200797
    • 1995-12-04
    • RESPIRONICS INC
    • ZDROJKOWSKI RONALD JESTES MARK
    • A61B5/08A61M16/00A61B5/087A61M16/06A61M16/20A62B7/00
    • Aparato de presión de vías aéreas positiva de dos niveles para suministrar gas de respiración a las vías respiratorias del paciente (12) a una presión de vías aéreas positiva de alto y bajo nivel, de manera alterna, que comprende: unos medios (20) de generación de presión para generar el caudal de gas de respiración; un conducto con un primer extremo acoplado a una salida de los medios de generación de presión y adaptado para transportar el flujo de gas de respiración; una máscara de respiración (22) adaptada para que el paciente la lleve puesta, acoplada a un segundo extremo del circuito y adaptada para comunicar el flujo de gas de respiración con las vías respiratorias del paciente cuando dicho paciente lleva puesta la máscara, definiendo dicho conducto y dicha máscara de respiración un circuito presurizado del paciente; unos medios de descarga (24) asociados al circuito del paciente para proporcionar un flujo de gas de descarga desde el circuito del paciente hacia la atmósfera; unos medios sensores de flujo (28) para medir el flujo total de gas de respiración que pasa por el circuito del paciente; unos medios sensores de presión (26) acoplados al circuito del paciente para medir la presión P(t) de gas dentro de dicho circuito del paciente, y unos medios de procesamiento para: (I) calcular, en función de la salida de los medios sensores de flujo, una tasa media de fuga de gas desde el circuito del paciente durante un período determinado; (II) determinar, en función de los medios sensores de presión, la media de la raíz cuadrada de la presión de gas de respiración en el circuito presurizado del paciente durante un período determinado; (III) determinar una constante K que representa una constante de proporcionalidad para un orificio hipotético que representa la fuga de gas de todas las fuentes de fuga, basándose la determinación de K en la tasa media de fuga y en la media de la raíz cuadrada de la presión de gas de respiración durante un período determinado, y (IV) multiplicar, durante un período posterior determinado, la raíz cuadrada de la presión instantánea de gas de respiración en el circuito presurizado del paciente por la constante K de proporcionalidad calculada para el período anterior, para derivar una tasa instantánea de fuga de gas desde el circuito del paciente.