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1. 发明申请

WO2011156624A2 DUAL MODE ULTRASOUND TRANSDUCER (DMUT) SYSTEM AND METHOD FOR CONTROLLING DELIVERY OF ULTRASOUND THERAPY 审中-公开
标题翻译：双模式超声波传感器（DMUT）系统和控制超声波治疗方法
公开(公告)号：WO2011156624A2
公开(公告)日：2011-12-15
申请号：PCT/US2011/039837
申请日：2011-06-09
申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA , EBBINI, Emad, S. , CASPER, Andrew, J. , LIU, Dalong , BALLARD, John, R.
发明人： EBBINI, Emad, S. , CASPER, Andrew, J. , LIU, Dalong , BALLARD, John, R.
IPC分类号： A61N7/02
CPC分类号： A61B8/54 , A61B8/0816 , A61B8/4488 , A61B8/485 , A61B8/5223 , A61N7/02 , A61N2007/0052 , A61N2007/0095 , A61N2007/027
摘要： A dual-mode ultrasound system provides real-time imaging and therapy delivery using the same transducer elements of a transducer array. The system may use a multi¬ channel driver to drive the elements of the array. The system uses a real-time monitoring and feedback image control of the therapy based on imaging data acquired using the dual- mode ultrasound array (DMUA) of transducer elements. Further, for example, multi¬ modal coded excitation may be used in both imaging and therapy modes. Still further, for example, adaptive, real-time refocusing for improved imaging and therapy can be achieved using, for example, array directivity vectors obtained from DMUA pulse-echo data.
摘要翻译：双模式超声系统使用换能器阵列的相同换能器元件提供实时成像和治疗传递。系统可以使用多通道驱动器来驱动阵列的元件。该系统基于使用传感器元件的双模式超声阵列（DMUA）获取的成像数据，对治疗进行实时监测和反馈图像控制。此外，例如，可以在成像和治疗模式中使用多模式编码激励。此外，例如，可以使用例如从DMUA脉冲 - 回波数据获得的阵列方向性矢量来实现用于改善成像和治疗的自适应，实时重新聚焦。

2. 发明申请

WO2012142455A2 VASCULAR CHARACTERIZATION USING ULTRASOUND IMAGING 审中-公开
标题翻译：使用超声波成像进行血管表征
公开(公告)号：WO2012142455A2
公开(公告)日：2012-10-18
申请号：PCT/US2012/033584
申请日：2012-04-13
申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA , EBBINI, Emad S. , LIU, Dalong , WAN, Yayun , CASPER, Andrew J.
发明人： EBBINI, Emad S. , LIU, Dalong , WAN, Yayun , CASPER, Andrew J.
IPC分类号： A61B8/00
CPC分类号： A61B8/0891 , A61B8/06 , A61B8/085 , A61B8/485 , A61B8/486
摘要： Ultrasound methods and/or systems provide for the motion tracking of both vessel wall motion and blood flow (e.g., with use of high frame rate ultrasound pulse echo data and speckle tracking both wall motion and flow can be tracked simultaneously).
摘要翻译：超声方法和/或系统提供血管壁运动和血流两者的运动跟踪（例如，利用高帧频超声波脉冲回波数据和斑点跟踪，可以同时跟踪壁运动和流动）。

3. 发明申请

WO2015013196A2 ULTRASOUND IMAGE FORMATION AND/OR RECONSTRUCTION USING MULTIPLE FREQUENCY WAVEFORMS 审中-公开
标题翻译：超声图像的形成和/或使用多频率波形重建
公开(公告)号：WO2015013196A2
公开(公告)日：2015-01-29
申请号：PCT/US2014/047430
申请日：2014-07-21
申请人： REGENTS OF THE UNIVERSITY OF MINNESOTA
发明人： EBBINI, Emad, S. , LIU, Dalong , CASPER, Andrew, J.
IPC分类号： G01S15/89
CPC分类号： A61B8/14 , A61B8/0891 , A61B8/4438 , A61B8/5207 , A61N7/00 , G01S7/5202 , G01S7/52046 , G01S15/8915 , G01S15/8952 , G01S15/8959 , G01S15/8997
摘要： Ultrasound adaptive imaging methods and/or systems provide for modification of waveform generation to drive a plurality of transducer elements. The modification may be based on at least one of contrast ratio or signal to noise ratio as determined with respect to control points in a region of interest. Further, image reconstruction may be performed upon separating, from pulse echo data received, at least a portion thereof received at each ultrasound transducer element from the region of interest in response to the delivered ultrasound energy corresponding to a single frequency of one or more image frequencies within a transducer apparatus bandwidth. The image reconstructed from the separated pulse-echo data corresponding to the single frequency of the one or more image frequencies may be used alone or combined with like image data (e.g., to provide an image representative of one or more properties in the region of interest).
摘要翻译：超声波自适应成像方法和/或系统提供对波形生成的修改以驱动多个换能器元件。修改可以基于关于感兴趣区域中的控制点所确定的对比度或信噪比中的至少一个。此外，响应于与一个或多个图像频率的单个频率相对应的所递送的超声能量，在从所接收的脉冲回波数据中分离出在每个超声换能器元件处从感兴趣区域接收的其至少一部分时，可以执行图像重建在换能器装置带宽内。从与一个或多个图像频率的单个频率对应的分离的脉冲回波数据重建的图像可以单独使用或与相似的图像数据组合使用（例如，以提供代表感兴趣区域中的一个或多个特性的图像）。

4. 发明公开

EP3719531A1 ULTRASOUND IMAGE FORMATION AND/OR RECONSTRUCTION USING MULTIPLE FREQUENCY WAVEFORMS 审中-公开
公开(公告)号：EP3719531A1
公开(公告)日：2020-10-07
申请号：EP20176810.8
申请日：2014-07-21
申请人： Regents of the University of Minnesota
发明人： EBBINI, Emad S. , LIU, Dalong , CASPER, Andrew J.
IPC分类号： G01S7/52
摘要： Ultrasound adaptive imaging methods and/or systems provide for modification of waveform generation to drive a plurality of transducer elements. The modification may be based on at least one of contrast ratio or signal to noise ratio as determined with respect to control points in a region of interest. Further, image reconstruction may be performed upon separating, from pulse echo data received, at least a portion thereof received at each ultrasound transducer element from the region of interest in response to the delivered ultrasound energy corresponding to a single frequency of one or more image frequencies within a transducer apparatus bandwidth. The image reconstructed from the separated pulse-echo data corresponding to the single frequency of the one or more image frequencies may be used alone or combined with like image data (e.g., to provide an image representative of one or more properties in the region of interest).

5. 发明公开

EP3406299A1 DUAL MODE ULTRASOUND TRANSDUCER (DMUT) SYSTEM AND METHOD FOR CONTROLLING DELIVERY OF ULTRASOUND THERAPY 有权
公开(公告)号：EP3406299A1
公开(公告)日：2018-11-28
申请号：EP18165565.5
申请日：2011-06-09
申请人： Regents of the University of Minnesota
发明人： EBBINI, Emad S. , CASPER, Andrew J. , LIU, Dalong , BALLARD, John R.
IPC分类号： A61N7/00 , A61B8/00
CPC分类号： A61B8/54 , A61B8/0816 , A61B8/4488 , A61B8/485 , A61B8/5223 , A61N7/02 , A61N2007/0052 , A61N2007/0095 , A61N2007/027
摘要： A dual-mode ultrasound system provides real-time imaging and therapy delivery using the same transducer elements of a transducer array. The system may use a multichannel driver to drive the elements of the array. The system uses a real-time monitoring and feedback image control of the therapy based on imaging data acquired using the dual-mode ultrasound array (DMUA) of transducer elements. Further, for example, multi-modal coded excitation may be used in both imaging and therapy modes. Still further, for example, adaptive, real-time refocusing for improved imaging and therapy can be achieved using, for example, array directivity vectors obtained from DMUA pulse-echo data.

6. 发明公开

EP3025166A2 ULTRASOUND IMAGE FORMATION AND/OR RECONSTRUCTION USING MULTIPLE FREQUENCY WAVEFORMS 有权
标题翻译：超声成像和/或重建使用具有多个频率WAVEFORMS
公开(公告)号：EP3025166A2
公开(公告)日：2016-06-01
申请号：EP14750404.7
申请日：2014-07-21
申请人： Regents of the University of Minnesota
发明人： EBBINI, Emad S. , LIU, Dalong , CASPER, Andrew J.
IPC分类号： G01S15/89 , G01S7/52 , G10K11/34 , A61B8/14
CPC分类号： A61B8/14 , A61B8/0891 , A61B8/4438 , A61B8/5207 , A61N7/00 , G01S7/5202 , G01S7/52046 , G01S15/8915 , G01S15/8952 , G01S15/8959 , G01S15/8997
摘要： Ultrasound adaptive imaging methods and/or systems provide for modification of waveform generation to drive a plurality of transducer elements. The modification may be based on at least one of contrast ratio or signal to noise ratio as determined with respect to control points in a region of interest. Further, image reconstruction may be performed upon separating, from pulse echo data received, at least a portion thereof received at each ultrasound transducer element from the region of interest in response to the delivered ultrasound energy corresponding to a single frequency of one or more image frequencies within a transducer apparatus bandwidth. The image reconstructed from the separated pulse-echo data corresponding to the single frequency of the one or more image frequencies may be used alone or combined with like image data (e.g., to provide an image representative of one or more properties in the region of interest).
摘要翻译：超声成像自适应方法和/或系统提供波形产生的修改，以驱动换能器元件的复数。该修改可以基于的对比度或信号的至少一个的信噪比为确定性相对于在感兴趣的区域，以控制点开采。此外，图像重构可以在分离来进行，从脉冲回波数据接收，至少其一部分在从感兴趣区域中的每个超声换能器元件响应于所递送的超声能量对应于一个或更多个图像的频率的单一频率上接收一个换能器装置带宽内。从分离的脉冲 - 回波数据对应于所述一个或多个图像频率的单一频率重建的图像可以被单独使用或与类似的图像数据（例如，结合在感兴趣的区域，以提供图像代表的一个或多个属性的）。

7. 发明公开

EP3495022A3 VASCULAR CHARACTEIZATION USING ULTRASOUND IMAGING 有权
公开(公告)号：EP3495022A3
公开(公告)日：2019-10-02
申请号：EP18193572.7
申请日：2012-04-13
申请人： Regents of the University of Minnesota
发明人： EBBINI, Emad S. , LIU, Dalong , CASPER, Andrew J. , WAN, Yayun
IPC分类号： A61N7/00 , A61B8/00
摘要： Ultrasound methods and/or systems provide for the motion tracking of both vessel wall motion and blood flow (e.g., with use of high frame rate ultrasound pulse echo data and speckle tracking both wall motion and flow can be tracked simultaneously).

8. 发明授权

EP2579944B1 DUAL MODE ULTRASOUND TRANSDUCER (DMUT) SYSTEM AND METHOD FOR CONTROLLING DELIVERY OF ULTRASOUND THERAPY 有权
标题翻译：双模式超声换能器（DMUT）系统和用于控制输送超声疗法的方法
公开(公告)号：EP2579944B1
公开(公告)日：2018-04-04
申请号：EP11741319.5
申请日：2011-06-09
申请人： Regents Of The University Of Minnesota
发明人： EBBINI, Emad, S. , CASPER, Andrew, J. , LIU, Dalong , BALLARD, John, R.
IPC分类号： A61N7/00 , A61B8/00
CPC分类号： A61B8/54 , A61B8/0816 , A61B8/4488 , A61B8/485 , A61B8/5223 , A61N7/02 , A61N2007/0052 , A61N2007/0095 , A61N2007/027
摘要： A dual-mode ultrasound system provides real-time imaging and therapy delivery using the same transducer elements of a transducer array. The system may use a multichannel driver to drive the elements of the array. The system uses a real-time monitoring and feedback image control of the therapy based on imaging data acquired using the dual-mode ultrasound array (DMUA) of transducer elements. Further, for example, multimodal coded excitation may be used in both imaging and therapy modes. Still further, for example, adaptive, real-time refocusing for improved imaging and therapy can be achieved using, for example, array directivity vectors obtained from DMUA pulse-echo data.

9. 发明公开

EP2696771A2 VASCULAR CHARACTERIZATION USING ULTRASOUND IMAGING 有权转让
标题翻译： VASKULÄRECHARAKTERISIERUNG麻醉机超声波清洗机
公开(公告)号：EP2696771A2
公开(公告)日：2014-02-19
申请号：EP12715304.7
申请日：2012-04-13
申请人： Regents Of The University Of Minnesota
发明人： EBBINI, Emad S. , LIU, Dalong , WAN, Yayun , CASPER, Andrew J.
IPC分类号： A61B8/08 , A61B8/06
CPC分类号： A61B8/0891 , A61B8/06 , A61B8/085 , A61B8/485 , A61B8/486
摘要： Ultrasound methods and/or systems provide for the motion tracking of both vessel wall motion and blood flow (e.g., with use of high frame rate ultrasound pulse echo data and speckle tracking both wall motion and flow can be tracked simultaneously).
摘要翻译：超声方法和/或系统提供血管壁运动和血流两者的运动跟踪（例如，利用高帧频超声波脉冲回波数据和斑点跟踪，可以同时跟踪壁运动和流动）。

10. 发明公开

EP3495022A2 VASCULAR CHARACTEIZATION USING ULTRASOUND IMAGING 有权
公开(公告)号：EP3495022A2
公开(公告)日：2019-06-12
申请号：EP18193572.7
申请日：2012-04-13
申请人： Regents of the University of Minnesota
发明人： EBBINI, Emad S. , LIU, Dalong , CASPER, Andrew J. , WAN, Yayun
IPC分类号： A61N7/00 , A61B8/00
摘要： Ultrasound methods and/or systems provide for the motion tracking of both vessel wall motion and blood flow (e.g., with use of high frame rate ultrasound pulse echo data and speckle tracking both wall motion and flow can be tracked simultaneously).

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