专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2016071321A2 LUNG CANCER SUB-TYPING METHOD 审中-公开
标题翻译：肺癌分型方法
公开(公告)号：WO2016071321A2
公开(公告)日：2016-05-12
申请号：PCT/EP2015/075556
申请日：2015-11-03
申请人： RANDOX LABORATORIES LTD
发明人： LOWRY, Philip , MCCONNELL, Ivan , FITZGERALD, Peter , CHACKO, Alex
IPC分类号： G01N33/574
CPC分类号： G01N33/57423 , G01N2333/4737 , G01N2800/52 , G01N2800/60
摘要： The current invention provides methods of aiding in the differential diagnosis of small cell and non-small cell lung cancer. The methods are based on novel combinations of biomarkers including CRP, D-dimer, NSE, NGAL and VEGF. The biomarker combinations can be implemented in the form of a multi-analyte panel which could be used in clinical situations to differentiate between the two forms of lung cancer. This would increase the proportion of patients receiving accurate diagnosis of lung tumour type, allowing for earlier commencement of treatment at lower cost to the healthcare provider, and ultimately improving lung cancer survival rates.
摘要翻译：本发明提供了帮助小细胞和非小细胞肺癌鉴别诊断的方法。该方法基于生物标志物，包括CRP，D-二聚体，NSE，NGAL和VEGF的新型组合。生物标志物组合可以以多分析物面板的形式实施，其可用于临床情况以区分两种形式的肺癌。这将增加接受肺肿瘤类型准确诊断的患者的比例，从而能够以更低的成本开始对医疗保健提供者进行治疗，并最终提高肺癌的存活率。

2. 发明申请

WO2015155513A1 DIAGNOSIS OF CANCER BY DETECTING DIMERIC IL-18 审中-公开
标题翻译：通过检测二维IL-18诊断癌症
公开(公告)号：WO2015155513A1
公开(公告)日：2015-10-15
申请号：PCT/GB2015/051052
申请日：2015-04-02
申请人： RANDOX LABORATORIES LTD
发明人： CHACKO, Alex , MCCONNELL, Ivan , FITZGERALD, Peter , LAMONT, John V.
IPC分类号： G01N33/574
CPC分类号： G01N33/57484 , G01N33/6869 , G01N2333/54 , G01N2800/52
摘要： The present invention describes methods for screening for cancer in a subject, by measuring the level of dimeric IL-18 in a sample obtained from the subject, and comparing that level with the level in a normal control sample. The present invention also describes an assay for screening for cancer in a subject, by measuring the level of dimeric IL-18 in a sample obtained from the subject, whereby an elevated level of dimeric IL-18 is indicative of cancer.
摘要翻译：本发明描述了通过测量从受试者获得的样品中的二聚体IL-18的水平，并将该水平与正常对照样品中的水平进行比较来筛选受试者中癌症的方法。本发明还描述了通过测量从受试者获得的样品中的二聚体IL-18的水平来筛选受试者中的癌症的测定，由此提高的二聚体IL-18水平是癌症的指示。

3. 发明授权

EP3215851B1 LUNG CANCER SUB-TYPING METHOD 有权
公开(公告)号：EP3215851B1
公开(公告)日：2020-07-15
申请号：EP15828333.3
申请日：2015-11-03
申请人： Randox Laboratories Ltd.
发明人： LOWRY, Philip , MCCONNELL, Ivan , FITZGERALD, Peter , CHACKO, Alex
IPC分类号： G01N33/574

4. 发明公开

EP3215851A2 LUNG CANCER SUB-TYPING METHOD 有权
标题翻译：肺癌亚型分型法
公开(公告)号：EP3215851A2
公开(公告)日：2017-09-13
申请号：EP15828333.3
申请日：2015-11-03
申请人： Randox Laboratories Ltd.
发明人： LOWRY, Philip , MCCONNELL, Ivan , FITZGERALD, Peter , CHACKO, Alex
IPC分类号： G01N33/574
摘要： The current invention provides methods of aiding in the differential diagnosis of small cell and non-small cell lung cancer. The methods are based on novel combinations of biomarkers including CRP, D-dimer, NSE, NGAL and VEGF. The biomarker combinations can be implemented in the form of a multi-analyte panel which could be used in clinical situations to differentiate between the two forms of lung cancer. This would increase the proportion of patients receiving accurate diagnosis of lung tumour type, allowing for earlier commencement of treatment at lower cost to the healthcare provider, and ultimately improving lung cancer survival rates.
摘要翻译：本发明提供了辅助小细胞和非小细胞肺癌鉴别诊断的方法。这些方法基于包括CRP，D-二聚体，NSE，NGAL和VEGF的生物标志物的新组合。生物标志物组合可以以多分析物组的形式实施，其可用于临床情况以区分两种形式的肺癌。这将增加接受肺部肿瘤类型准确诊断的患者比例，使医疗服务提供商能够以较低的成本提前开始治疗，并最终提高肺癌的存活率。

5. 发明授权

EP3129785B1 DIAGNOSIS OF CANCER BY DETECTING DIMERIC IL-18 有权
公开(公告)号：EP3129785B1
公开(公告)日：2019-02-27
申请号：EP15715807.2
申请日：2015-04-02
申请人： Randox Laboratories Ltd.
发明人： CHACKO, Alex , MCCONNELL, Ivan , FITZGERALD, Peter , LAMONT, John V.
IPC分类号： G01N33/574

6. 发明公开

EP3129785A1 DIAGNOSIS OF CANCER BY DETECTING DIMERIC IL-18 有权
标题翻译： DIAGNOSE VON KREBS DURCH NACHWEIS VON DIMEREM IL-18
公开(公告)号：EP3129785A1
公开(公告)日：2017-02-15
申请号：EP15715807.2
申请日：2015-04-02
申请人： Randox Laboratories Ltd.
发明人： CHACKO, Alex , MCCONNELL, Ivan , FITZGERALD, Peter , LAMONT, John V.
IPC分类号： G01N33/574
CPC分类号： G01N33/57484 , A61P35/00 , A61P35/04 , C07K14/54 , G01N33/53 , G01N33/57423 , G01N33/6869 , G01N2333/54 , G01N2800/52
摘要： The present invention also describes an assay for screening for cancer in a subject, by measuring the level of dimeric IL-18 in a sample obtained from the subject, whereby an elevated level of dimeric IL-18 is indicative of cancer.
摘要翻译：本发明还描述了通过测量从受试者获得的样品中二聚体IL-18的水平，从而提高水平的二聚体IL-18指示癌症，从而筛选受试者中的癌症。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式