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    • 2. 发明申请
    • METHODS AND SYSTEMS FOR GENOME COMPARISON
    • 基因组比较的方法和系统
    • WO2015140794A1
    • 2015-09-24
    • PCT/IL2015/050279
    • 2015-03-16
    • RAMOT AT TEL-AVIV UNIVERSITY LTD.
    • SHOMRON, NoamISAKOV, OferCELNIKER, GershonPILLAR, Nir
    • G06F19/22G06F19/28C12Q1/68
    • G06F19/28C12Q1/68G06F19/18G06F19/22
    • There is provided a method for matching subject data to database patient data based on matching phenotypes and related genetic sequences, comprising: receiving a dataset including at least one phenotype disease description of a subject and a genetic sequence of the subject, the phenotype disease description describing clinically significant manifestations of disease in the subject; calculating a ranking score for each of a dataset of patients, the ranking score indicative of a similarity correlation between the dataset of each respective patient and the dataset of the subject, wherein the related genetic sequences of the dataset of patients are underlying genetic mutations attributable to the at least one phenotypic disease description; matching the dataset of the subject with at least one dataset of patients according to a requirement of the ranking score; and providing data indicative of the matched patients.
    • 提供了一种基于匹配表型和相关遗传序列将主题数据与数据库患者数据进行匹配的方法,包括:接收包含受试者的至少一种表型疾病描述和受试者的遗传序列的数据集,所述表型疾病描述描述 临床上主要疾病的重要表现; 计算每个患者数据集的排名得分,所述排名得分表示每个患者的数据集与受试者的数据集之间的相似性相关性,其中患者数据集的相关基因序列是可归因于 至少一种表型疾病描述; 根据排名分数的要求,将受试者的数据集与患者的至少一个数据集进行匹配; 并提供指示匹配患者的数据。
    • 3. 发明公开
    • METHODS AND SYSTEMS FOR GENOME COMPARISON
    • VERFAHREN UND SYSTEMEFÜRGENOMVERGLEICH
    • EP3120278A1
    • 2017-01-25
    • EP15764372.7
    • 2015-03-16
    • Ramot at Tel-Aviv University Ltd.
    • SHOMRON, NoamISAKOV, OferCELNIKER, GershonPILLAR, Nir
    • G06F19/22G06F19/28C12Q1/68
    • G06F19/28C12Q1/68G06F19/18G06F19/22
    • There is provided a method for matching subject data to database patient data based on matching phenotypes and related genetic sequences, comprising: receiving a dataset including at least one phenotype disease description of a subject and a genetic sequence of the subject, the phenotype disease description describing clinically significant manifestations of disease in the subject; calculating a ranking score for each of a dataset of patients, the ranking score indicative of a similarity correlation between the dataset of each respective patient and the dataset of the subject, wherein the related genetic sequences of the dataset of patients are underlying genetic mutations attributable to the at least one phenotypic disease description; matching the dataset of the subject with at least one dataset of patients according to a requirement of the ranking score; and providing data indicative of the matched patients.
    • 提供了一种用于基于匹配表型和相关遗传序列将主题数据与数据库患者数据进行匹配的方法,包括:接收包含受试者的至少一种表型疾病描述和受试者的遗传序列的数据集,所述表型疾病描述描述 临床上主要表现为疾病; 计算每个患者数据集的排名得分,所述排名得分表示每个患者的数据集与所述受试者的数据集之间的相似性相关性,其中所述患者数据集的相关遗传序列是可归因于 至少一种表型疾病描述; 根据排名分数的要求,将受试者的数据集与患者的至少一个数据集进行匹配; 并提供指示匹配患者的数据。