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1. 发明申请

US20140275617A1 STEREOSPECIFIC SYNTHESIS PROCESS FOR TRETINOIN COMPOUNDS 有权
标题翻译： TRETINOIN化合物的立体合成方法
公开(公告)号：US20140275617A1
公开(公告)日：2014-09-18
申请号：US14117343
申请日：2012-05-07
申请人： Qingjun Deng , Shaohui Wang , Qiang Zhu , Taiping Gao , Yongsheng Li
发明人： Qingjun Deng , Shaohui Wang , Qiang Zhu , Taiping Gao , Yongsheng Li
IPC分类号： C07C51/00
CPC分类号： C07C51/00 , C07C51/353 , C07C403/20 , C07C2601/16 , C07C59/64
摘要： A stereospecific synthesis process for tretinoin compounds comprises the following steps: using substituted triphenyl phosphine salt and β-formyl crotonic acid as raw material to carry out WITTIG reaction under the action of alkali; then adjusting the pH of the reaction liquid to 5-10; adding palladium compound or rhodium compound to carry out isomerization directly and obtain tretinoin compounds with desired configuration. The product yield of the process is high and the intermediate product in the reaction dose not need to be separated. The process is easy to operate and can save the production cost and as well is suitable for industrial production.
摘要翻译：维A酸化合物的立体特异性合成方法包括以下步骤：使用取代的三苯基膦盐和巴豆酮基巴豆酸作为原料，在碱的作用下进行WITTIG反应; 然后将反应液的pH调节至5-10; 加入钯化合物或铑化合物直接进行异构化，得到具有所需结构的维甲酸化合物。该方法的产物产率高，反应中的中间产物不需要分离。该工艺易于操作，可节省生产成本，适用于工业生产。

2. 发明授权

US08835680B1 Stereospecific synthesis process for tretinoin compounds 有权
标题翻译：维A酸化合物的立体定向合成方法
公开(公告)号：US08835680B1
公开(公告)日：2014-09-16
申请号：US14117343
申请日：2012-05-07
申请人： Qingjun Deng , Shaohui Wang , Qiang Zhu , Taiping Gao , Yongsheng Li
发明人： Qingjun Deng , Shaohui Wang , Qiang Zhu , Taiping Gao , Yongsheng Li
IPC分类号： C07C61/16 , C07C53/134 , C07C51/00
CPC分类号： C07C51/00 , C07C51/353 , C07C403/20 , C07C2601/16 , C07C59/64
摘要： A stereospecific synthesis process for tretinoin compounds comprises the following steps: using substituted triphenyl phosphine salt and β-formyl crotonic acid as raw material to carry out WITTIG reaction under the action of alkali; then adjusting the pH of the reaction liquid to 5-10; adding palladium compound or rhodium compound to carry out isomerization directly and obtain tretinoin compounds with desired configuration. The product yield of the process is high and the intermediate product in the reaction dose not need to be separated. The process is easy to operate and can save the production cost and as well is suitable for industrial production.
摘要翻译：维A酸化合物的立体特异性合成方法包括以下步骤：使用取代的三苯基膦盐和巴豆酮基巴豆酸作为原料，在碱的作用下进行WITTIG反应; 然后将反应液的pH调节至5-10; 加入钯化合物或铑化合物直接进行异构化，得到具有所需结构的维甲酸化合物。该方法的产物产率高，反应中的中间产物不需要分离。该工艺易于操作，可节省生产成本，适用于工业生产。

3. 发明授权

US07937680B2 Method and apparatus for verifying specification, and computer product 有权
标题翻译：用于验证规格的方法和装置以及计算机产品
公开(公告)号：US07937680B2
公开(公告)日：2011-05-03
申请号：US11214848
申请日：2005-08-31
申请人： Qiang Zhu , Ryosuke Oishi , Tsuneo Nakata , Takashi Hasegawa
发明人： Qiang Zhu , Ryosuke Oishi , Tsuneo Nakata , Takashi Hasegawa
IPC分类号： G06F17/50 , G06F21/00 , G06Q20/00
CPC分类号： G06F8/10 , G06Q20/4012
摘要： An apparatus for verifying a specification includes a use-case extracting unit, a first setting unit, an operation extracting unit, a second setting unit, and a determining unit. The use-case extracting unit extracts an unprocessed use case from specification data. The first setting unit sets a condition based on a precondition, a postcondition, and an invariant condition for the use case. The operation extracting unit selects an event flow of an unprocessed path from the specification data and extracts an unprocessed operation (description) from the event flow selected. The second setting unit sets a precondition and a postcondition for the operation based on the extracted operation (description). The determining unit determines whether the invariant condition is valid.
摘要翻译：用于验证规范的装置包括用例提取单元，第一设置单元，操作提取单元，第二设置单元和确定单元。用例提取单元从规范数据中提取未处理的用例。第一设置单元基于用例的前提条件，后置条件和不变条件设置条件。操作提取单元从指定数据中选择未处理路径的事件流，并从所选择的事件流中提取未处理的操作（描述）。第二设定单元基于提取的操作（描述）设置操作的前提条件和后置条件。确定单元确定不变条件是否有效。

4. 发明授权

US07821228B2 Mobile phone charger 失效
标题翻译：手机充电器
公开(公告)号：US07821228B2
公开(公告)日：2010-10-26
申请号：US11946861
申请日：2007-11-29
申请人： Qiang Zhu , Shan-Ming Liao
发明人： Qiang Zhu , Shan-Ming Liao
IPC分类号： H02J7/00
CPC分类号： H02J7/0054
摘要： A charger includes a battery module, a boosting and charging circuit, a low voltage boosting circuit, and a charging interface. The battery module provides an operating voltage for the boosting and charging circuit and the low voltage boosting circuit. When the operating voltage is greater than a reference voltage of the boosting and charging circuit, the boosting and charging circuit module works and outputs a charging voltage to the charging interface. When the operating voltage is smaller than the reference voltage of the boosting and charging circuit but greater than a starting voltage of the low voltage boosting circuit, the low voltage boosting circuit works and boosts the operating voltage to the boosting and charging circuit, and then the boosting and charging circuit module works and outputs the charging voltage to the charging interface for the mobile phone.
摘要翻译：充电器包括电池模块，升压和充电电路，低压升压电路和充电接口。电池模块为升压和充电电路和低压升压电路提供工作电压。当工作电压大于升压和充电电路的参考电压时，升压和充电电路模块工作并向充电接口输出充电电压。当工作电压小于升压和充电电路的参考电压但大于低压升压电路的启动电压时，低压升压电路工作并将工作电压升压到升压和充电电路，然后升压和充电电路模块工作，并将充电电压输出到手机的充电接口。

5. 发明申请

US20090326906A1 VERIFICATION SUPPORT APPARATUS, VERIFICATION SUPPORT METHOD, AND COMPUTER PRODUCT 审中-公开
标题翻译：验证支持设备，验证支持方法和计算机产品
公开(公告)号：US20090326906A1
公开(公告)日：2009-12-31
申请号：US12372816
申请日：2009-02-18
申请人： Akio MATSUDA , Ryosuke Oishi , Qiang Zhu
发明人： Akio MATSUDA , Ryosuke Oishi , Qiang Zhu
IPC分类号： G06F9/44
CPC分类号： G06F11/3608
摘要： A computer-readable recording medium stores therein a verification support program that causes a computer to execute selecting arbitrarily a use case from a use case diagram for a verification target; extracting a precondition and a postcondition of the use case selected at the selecting; and converting, to a Kripke model, a finite state machine model corresponding to the use case selected at the selecting. The verification support program further causes the computer to execute specifying, based on the precondition and the postcondition extracted at the extracting, a Kripke initial state, a Kripke precondition, and a Kripke postcondition of the Kripke model obtained at the converting; and generating, based on the Kripke precondition and the Kripke postcondition specified at the specifying, a Kripke property of the use case selected at the selecting.
摘要翻译：计算机可读记录介质中存储有一个验证支持程序，该程序使计算机从用于验证目标的用例图中任意选择使用案例; 提取在选择中选择的用例的前提条件和后置条件; 并将Kripke模型转换成与选择时选择的用例对应的有限状态机模型。验证支持程序进一步使计算机根据在提取时提取的前提条件和后置条件执行指定，该转换时获得的Kripke模型的Kripke初始状态，Kripke前提条件和Kripke后置条件; 并根据指定的Kripke前提条件和Kripke后置条件生成在选择中选择的用例的Kripke属性。

6. 发明申请

US20090160091A1 Method and apparatus for manufacturing turbine or compressor wheels 有权
标题翻译：用于制造涡轮或压缩机轮的方法和装置
公开(公告)号：US20090160091A1
公开(公告)日：2009-06-25
申请号：US11989271
申请日：2006-06-29
申请人： Qiang Zhu , Andrew Phillip Jackson
发明人： Qiang Zhu , Andrew Phillip Jackson
IPC分类号： B22D17/00 , B29C45/34
CPC分类号： B22C9/06 , B22D17/007 , B22D17/22 , F04D29/284 , F05D2220/40
摘要： A method for forming a turbine or compressor wheel from a semi-solid material uses a die assembly that has an inner cartridge made up from a plurality of segments and an outer die. The semi-solid material is injected under pressure and high temperature into the die so that it flows into blade cavities defined between the segments of the cartridge. The cartridge is removed from the outer die and the segments are then separated to release the wheel.
摘要翻译：用于从半固体材料形成涡轮或压缩机叶轮的方法使用具有由多个段和外模构成的内筒的模组件。将半固体材料在压力和高温下注入模具中，使其流入限定在盒的段之间的叶片空腔。将盒从外模上拆下，然后分开该片以释放轮。

7. 发明申请

US20090121105A1 MOUNTING APPARATUS FOR DATA STORAGE DEVICE 失效
标题翻译：数据存储设备的安装设备
公开(公告)号：US20090121105A1
公开(公告)日：2009-05-14
申请号：US11953873
申请日：2007-12-11
申请人： Qiang Zhu , Jin-Man Chen
发明人： Qiang Zhu , Jin-Man Chen
IPC分类号： A47B96/06 , G06F1/16
CPC分类号： G06F1/187
摘要： A mounting apparatus is provided to readily fix a data storage device defining at least one hole in place. The mounting apparatus includes a bracket holding the storage device, a securing plate, and a pole coupled to the securing plate. The bracket defines at least one through hole corresponding to the hole of the storage device, and a positioning plate defining a sliding groove extends perpendicularly from the bracket. At least one post extends from the securing plate, and engages in the corresponding hole of the storage device to fasten the storage device. One end of the pole is pivotably mounted on the bracket, and the other end of the pole extends though the sliding groove of the positioning plate, and is slidable in the sliding groove to control the post of the securing plate to engage or disengage the hole of the storage device.
摘要翻译：提供了一种安装装置，用于容易地将限定至少一个孔的数据存储装置固定到位。安装装置包括保持存储装置的支架，固定板和联接到固定板的杆。支架限定与存储装置的孔对应的至少一个通孔，并且限定滑动槽的定位板垂直于支架延伸。至少一个支柱从固定板延伸，并且接合在存储装置的相应的孔中以紧固存储装置。杆的一端可枢转地安装在支架上，并且杆的另一端延伸穿过定位板的滑动槽，并且可在滑动槽中滑动以控制固定板的柱接合或脱开孔的存储设备。

8. 发明申请

US20070261012A1 Systematic generation of scenarios from specification sheet 有权
标题翻译：从规格表中系统地生成场景
公开(公告)号：US20070261012A1
公开(公告)日：2007-11-08
申请号：US11543025
申请日：2006-10-05
申请人： Akio Matsuda , Qiang Zhu , Ryosuke Oishi
发明人： Akio Matsuda , Qiang Zhu , Ryosuke Oishi
IPC分类号： G06F17/50
CPC分类号： G06F17/504
摘要： A method of generating a scenario includes generating a specification model by describing a specification in a predetermined descriptive language, extracting a plurality of operations from the specification model, generating a plurality of operation descriptions, each of which corresponds to one of the operations and includes an operation name and a constraint condition, generating at least one cause-effect graph that combines the operations based on the operation descriptions, and extracting as a scenario a series of operations from the cause-effect graph.
摘要翻译：一种产生场景的方法包括通过以预定描述语言描述规范来生成规范模型，从规范模型中提取多个操作，生成多个操作描述，每个操作描述对应于一个操作，并且包括操作名称和约束条件，生成组合基于操作描述的操作的至少一个因果图，并从因果图提取作为场景的一系列操作。

9. 发明授权

US09009009B2 Method for predicting optimized crystal structures 有权
标题翻译：预测优化晶体结构的方法
公开(公告)号：US09009009B2
公开(公告)日：2015-04-14
申请号：US13534861
申请日：2012-06-27
申请人： Artem R. Oganov , Andriy O. Lyakhov , Qiang Zhu
发明人： Artem R. Oganov , Andriy O. Lyakhov , Qiang Zhu
IPC分类号： G06F7/50 , G06N3/12 , G06F19/00
CPC分类号： G06N3/126 , G06F19/704 , G06F19/707
摘要： Disclosed is a method and system for prediction of an optimized crystal structure using an evolutionary algorithm that includes inputting characterization information of a chemical structure and input parameters, generating a first generation of crystal structures from the characterization information using symmetrical initialization, optimizing the chemical structure of the first generation of crystal structures according to the input parameters, inputting the optimized first generation of crystal structures into a niching algorithm, producing a child group of crystal structures from the parent group of crystal structures using a variation operator, and adding the child group of crystal structures to an optimal group of crystal structures to form a next generation, with the niching algorithm selecting an optimal group of crystal structures and a parent group of crystal structures from the first generation of crystal structures.
摘要翻译：公开了一种使用进化算法预测优化晶体结构的方法和系统，其包括输入化学结构和输入参数的表征信息，使用对称初始化从表征信息产生第一代晶体结构，优化化学结构的化学结构根据输入参数的第一代晶体结构，将优化的第一代晶体结构输入到niching算法中，使用变异算子从母体晶体结构组中产生一组晶体结构，并添加子组晶体结构到最佳组的晶体结构以形成下一代，其中niching算法从第一代晶体结构中选择最佳的晶体结构组和晶体结构的母体组。

10. 发明授权

US08143276B2 4-thio substituted quinoline and naphthyridine compounds 失效
标题翻译： 4-硫代取代的喹啉和萘啶化合物
公开(公告)号：US08143276B2
公开(公告)日：2012-03-27
申请号：US11895088
申请日：2007-08-22
申请人： Zhen Yang , Reza Fathi , Qiang Zhu , Hyun-Joon Cho , Yixin Liu , Anthony Sandrasagra , C. Richard Wobbe
发明人： Zhen Yang , Reza Fathi , Qiang Zhu , Hyun-Joon Cho , Yixin Liu , Anthony Sandrasagra , C. Richard Wobbe
IPC分类号： C07D215/38 , A61K31/04
CPC分类号： C07D215/36 , C07D471/04
摘要： The present invention relates to 4-thio substituted quinoline and naphthyridine derivatives and processes for their preparation. The invention also related to methods for treating infection of Hepatitis C virus by administering a 4-thio substituted quinoline or naphthyridine derivative.
摘要翻译：本发明涉及4-硫代取代的喹啉和萘啶衍生物及其制备方法。本发明还涉及通过施用4-硫代取代的喹啉或萘啶衍生物来治疗丙型肝炎病毒感染的方法。

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