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1. 发明专利

JP2007230878A Brain function ameliorant and brain function ameliorating composition containing the same 有权
标题翻译：脑功能调节因子和脑功能的组合物
公开(公告)号：JP2007230878A
公开(公告)日：2007-09-13
申请号：JP2006051013
申请日：2006-02-27
申请人： Pokka Corp , Koji Uchida , 浩二内田 , 株式会社ポッカコーポレーション
发明人： FUKUMOTO SHUICHI , OKADA SANENORI , UCHIDA KOJI , SHIBATA TAKAHIRO , NAKAHARA HIROKO , KITA NARUMI , YOKOGOSHI HIDEHIKO
IPC分类号： A61K31/353 , A23K1/16 , A23L1/30 , A61P25/28 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To obtain a brain function ameliorant having excellent enhancing action on nerve growth factor and ameliorating action on memory learning ability and a brain function ameliorating composition containing the same. SOLUTION: The brain function ameliorant comprises at least one kind of a component selected from eriodictyol, hesperetin and naringenin or at least one kind of a component selected from eriocitrin, hesperidin and naringin being their glycosides. Having enhancing action on nerve growth factor and ameliorating action on memory learning ability, the brain function ameliorant is useful as an active ingredient of a brain function ameliorating composition for a medicine, food and beverage, feed, etc. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：待解决的问题：获得对神经生长因子具有优异增强作用的脑功能改善剂和改善记忆学习能力的作用以及包含其的脑功能改善组合物。解决方案：脑功能改善剂包括至少一种选自欧洛昔康，橙皮素和柚皮苷或选自以下的至少一种选自以下的一种选自以下的一种成分：黑麦草素，橙皮苷和柚皮苷。具有增强神经生长因子的作用和改善记忆学习能力的作用，大脑功能改善剂可用作药物，食品和饮料，饲料等改善组合物的大脑功能的活性成分。版权所有（C））2007，JPO＆INPIT

2. 发明专利

JP2013075876A Nymphaeol containing solution and method for dispersing nymphaeol 有权
标题翻译： NYMPHAEOL包含解决方案和分解NYMPHAEOL的方法
公开(公告)号：JP2013075876A
公开(公告)日：2013-04-25
申请号：JP2011218048
申请日：2011-09-30
申请人： Pokka Corp , 株式会社ポッカコーポレーション
发明人： FUKUMOTO SHUICHI , KUMAGAI KENJI , NAKATANI KAZUKI
IPC分类号： A61K31/353 , A23L1/30 , A23L3/3544 , A61K8/49 , A61K9/08 , A61K36/00 , A61K36/18 , A61K47/10 , A61P17/18 , A61P31/04 , A61P35/00 , A61P39/06 , A61Q11/00 , A61Q19/00 , B01J13/00
摘要： PROBLEM TO BE SOLVED: To provide a nymphaeol containing solution capable of stably dispersing the nymphaeol in a water-based dispersion solvent, in nymphaeol containing solutions used by dispersing it in a water-based dispersion solvent, and a dispersing method for nymphaeols.SOLUTION: The nymphaeol containing solution, in nymphaeol solvents used for dispersing them in water-based dispersion solvents, is characterized by comprising at least one selected from solvents easily soluble in water-based dispersion solvents such as monohydric alcohols, dihydric alcohols, and trihydric alcohols, wherein the concentration of the nymphaeol in the nymphaeol containing solution is 8 mass% or less.
摘要翻译：要解决的问题：提供能够将淋巴酮稳定分散在水性分散溶剂中的含有阴离子的溶液，将其分散在水性分散溶剂中的含有阴离子的溶液中，以及分散方法。溶液：在用于将它们分散在水基分散溶剂中的尼莫酚溶剂中含有尼膜醇的溶液的特征在于包含至少一种选自易溶于水分散溶剂如一元醇，二元醇，和三元醇，其中含有止血薄荷溶液中的淋巴酮的浓度为8质量％以下。版权所有（C）2013，JPO＆INPIT

3. 发明专利

JP2009013080A Vascular endothelium function improver and nitrogen monoxide production promoter 审中-公开
标题翻译：血管内皮功能改善和一氧化氮生产促进剂
公开(公告)号：JP2009013080A
公开(公告)日：2009-01-22
申请号：JP2007174222
申请日：2007-07-02
申请人： Pokka Corp , 株式会社ポッカコーポレーション
发明人： SAEGUSA HIROAKI , HIRAMITSU MASANORI , FUKUMOTO SHUICHI , OKADA SANENORI
IPC分类号： A61K31/352 , A61K31/7048 , A61K36/75 , A61P9/14 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a vascular endothelium function improver excellent in activities for promoting the vascular endothelium function aggravated by a life-style related disease such as hypertension, and to provide a nitrogen monoxide production promoter. SOLUTION: The vascular endothelium function improver or the nitrogen monoxide production promoter comprises polyphenols originated from citrus as active ingredients. Preferably, the polyphenols are formulated as a polar solvent extract from the citrus fruits. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种血管内皮功能改善剂，其优异的活性用于促进由诸如高血压的生活方式相关疾病加重的血管内皮功能，并提供一氧化氮生产促进剂。解决方案：血管内皮功能改良剂或一氧化氮生产促进剂包含起源于柑橘作为活性成分的多酚。优选地，将多酚配制成来自柑橘类水果的极性溶剂提取物。版权所有（C）2009，JPO＆INPIT

4. 发明专利

JP2007308435A Brain function improver and brain function-improving composition containing the same 审中-公开
标题翻译：脑功能改善和脑功能改善组合物
公开(公告)号：JP2007308435A
公开(公告)日：2007-11-29
申请号：JP2006140699
申请日：2006-05-19
申请人： Pokka Corp , 株式会社ポッカコーポレーション
发明人： KAKO DAIYA , FUKUMOTO SHUICHI , YOKOGOSHI HIDEHIKO
IPC分类号： A61K31/045 , A23K1/16 , A23L1/30 , A23L2/52 , A61K31/11 , A61P25/28
摘要： PROBLEM TO BE SOLVED: To provide a brain function improver especially having excellent activities for improving memory learning ability, and a brain function-improving composition containing the improver. SOLUTION: The brain function improver contains at least one kind of a component selected from hexanal, hexenal, hexanol and hexenol as an active ingredient. The brain function improver is used as an active ingredient of the brain function-improving composition such as a medicine, a food and drink and a fodder because the brain function improver has especially the activities for improving the memory learning ability. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种脑功能改善剂，特别是具有提高记忆学习能力的优异活性，以及含有改善剂的脑功能改善组合物。解决方案：脑功能改进剂含有至少一种选自己醛，己烯醛，己醇和己烯醇的组分作为活性成分。脑功能改良剂被用作脑功能改善组合物的活性成分，例如药物，食物和饮料和饲料，因为大脑功能改良剂特别是提高记忆学习能力的活动。版权所有（C）2008，JPO＆INPIT

5. 发明专利

JP2005029560A Flavanone compound, antioxidant, antibacterial agent, antitumor agent, and beverage or food 有权
标题翻译： FLAVANONE化合物，抗氧化剂，抗菌剂，抗菌剂，饮料或食品
公开(公告)号：JP2005029560A
公开(公告)日：2005-02-03
申请号：JP2004123479
申请日：2004-04-19
申请人： Pokka Corp , 株式会社ポッカコーポレーション
发明人： KUMAZAWA SHIGENORI , NAKAYAMA TSUTOMU , SHIMOI KAYOKO , GOTO TAKATERU , FUKUMOTO SHUICHI , ARAGAKI TSUTOMU
IPC分类号： A23L1/30 , A61K31/352 , A61K35/64 , A61P1/14 , A61P31/04 , A61P35/00 , A61P39/06 , A61P43/00 , C07D311/32
CPC分类号： Y02A50/481
摘要： PROBLEM TO BE SOLVED: To provide a new flavanone compound having anti-oxidation, antitumor and antibacterial activities, etc., and an antioxidant, antibacterial agent, antitumor agent, and a beverage or food containing the flavanone compound. SOLUTION: This flavanone compound is 5,7,3',4'-tetrahydroxy-5'-C-geranylfalvanone expressed by the formula. All of the antioxidant, antibacterial agent and antitumor agent contain the flavanone compound as an active ingredient. The beverage and food contain the flavanone compound, antioxidant or antibacterial agent. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供具有抗氧化，抗肿瘤和抗菌活性的新型黄烷酮化合物，抗氧化剂，抗菌剂，抗肿瘤剂以及含有黄烷酮化合物的饮料或食品。解决方案：该黄烷酮化合物是由下式表示的5,7,3'，4'-四羟基-5'-碳基香叶基酮。所有的抗氧化剂，抗菌剂和抗肿瘤剂都含有黄烷酮化合物作为活性成分。饮料和食品含有黄烷酮化合物，抗氧化剂或抗菌剂。版权所有（C）2005，JPO＆NCIPI

6. 发明专利

JP2012006894A Method for producing macaranga tanarius extract, and solution of macaranga tanarius extract 有权
标题翻译：马齿苋提取物的制备方法和麦麸提取物的解决方案
公开(公告)号：JP2012006894A
公开(公告)日：2012-01-12
申请号：JP2010146926
申请日：2010-06-28
申请人： Momotani Juntendo:Kk , Pokka Corp , 株式会社ポッカコーポレーション , 株式会社桃谷順天館
发明人： KUMAGAI KENJI , FUKUMOTO SHUICHI , MATSUSHITA NAO , KODAMA TAKASHI
IPC分类号： A61K36/00 , A61K36/47 , A61P31/04 , A61P39/06
摘要： PROBLEM TO BE SOLVED: To solve the problems wherein, whereas a Macaranga tanarius extract is known as an antimicrobial agent, an antioxidant and a bactericide, when methanol, DMSO, ethanol, acetonitrile, acetone, ethyl acetate or the like is used as an extraction solvent for acquiring the Macaranga tanarius extract, if an acquired extract is added to an oral hygienic product, food, cosmetics or the like to acquired a final product, the solvent, even in the case of a trace quantity, may be contained in the final product, further, a Macaranga tanarius extract dissolved in ethanol among the extraction solvents has poor stability to lower a survival rate in the ethanol solution by being decomposed with the passage of time, and therefor it is necessary to pay attention to making full use of the acquired ethanol solution of the Macaranga tanarius extract as soon as possible.SOLUTION: This invention relates to: a method for extracting Macaranga tanarius by an extraction solvent containing one or more kinds selected from among oil and fat, waxes, fatty acids, esters, polyethylene glycol-16 macadamia oil, and 1,3-butylene glycol; and a Macaranga tanarius extract solution in which the Macaranga tanarius extract is used as a solute, and one or more kinds selected from among oil and fat, waxes, fatty acids, esters, polyethylene glycol-16 macadamia oil, and 1,3-butylene glycol are used as a solvent.
摘要翻译：要解决的问题为了解决当使用甲醇，DMSO，乙醇，乙腈，丙酮，乙酸乙酯等时，将马齿苋提取物称为抗微生物剂，抗氧化剂和杀菌剂的问题作为获取马齿苋提取物的提取溶剂，如果将获得的提取物添加到口腔卫生产品，食品，化妆品等中以获得最终产品，则即使在微量的情况下也可以含有溶剂在最终产品中，另外，提取溶剂中溶解在乙醇中的马齿香提取物具有差的稳定性，通过随时间分解来降低乙醇溶液中的存活率，因此需要注意使全部尽快使用马齿苋提取物获得的乙醇溶液。解决方案：本发明涉及一种通过含有选自油脂，蜡，脂肪酸，酯，聚乙二醇-16澳洲坚果油和1,3中的一种或多种的萃取溶剂萃取水extracting蓉的方法。丁二醇和马齿苋提取物溶液，其中使用马齿苋提取物作为溶质，并且选自油脂中的一种或多种，蜡，脂肪酸，酯，聚乙二醇-16澳洲坚果油和1,3-丁烯乙二醇用作溶剂。版权所有（C）2012，JPO＆INPIT

7. 发明专利

JP2009137869A Periodontal bacterial growth inhibitor, oral hygiene product, and food and drink 有权
标题翻译：周边细菌生长抑制剂，口服卫生用品，食品和饮料
公开(公告)号：JP2009137869A
公开(公告)日：2009-06-25
申请号：JP2007314796
申请日：2007-12-05
申请人： Pokka Corp , 株式会社ポッカコーポレーション
发明人： GOTO TAKATERU , FUKUMOTO SHUICHI
IPC分类号： A61K36/47 , A23L1/30 , A23L2/52 , A61K8/49 , A61K8/97 , A61K31/353 , A61K38/00 , A61P1/02 , A61P31/04 , A61Q11/00 , C07D311/32
CPC分类号： A61K8/498 , A23L2/44 , A23L2/52 , A23L3/3571 , A23L33/105 , A61K8/97 , A61K31/353 , A61K36/47 , A61Q11/00 , A61Q17/005 , C07D311/32
摘要： PROBLEM TO BE SOLVED: To provide a periodontal bacterial growth inhibitor which can be obtained from a raw material avoidable of the complication of a pretreatment, and to provide an oral hygiene product and food and drink comprising the inhibitor. SOLUTION: This periodontal bacterial growth inhibitor contains, as an active ingredient, at least an extract of Macaranga tanarius extracted from Macaranga tanarius with an extraction solvent containing an organic solvent. The Macaranga tanarius as a raw material for the extract of Macaranga tanarius is an evergreen broad-leaved tree belonging to Euphorbiaceae, genus Macaranga. The Macaranga tanarius grows extremely quickly among trees, and can also grow in a devastated land. The periodontal bacterial growth inhibitor can be added to, for example, an oral hygiene product, food and drink, and then used. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供可从避免预处理并发症的原料获得的牙周细菌生长抑制剂，以及提供包含抑制剂的口腔卫生产品和食品和饮料。解决方案：该牙周细菌生长抑制剂含有从马齿苋（Macaranga tanarius）中提取的至少一种从含有有机溶剂的提取溶剂中提取的马齿香（Macaranga tanari）的提取物作为活性成分。马齿苋作为金丝雀提取物的原料，是一种常绿阔叶树，属于Macaranga属的大戟科（Euphorbiaceae）。马齿苋的赤藓糖在树木中迅速增长，也可以在一片毁灭性的土地上种植。牙周细菌生长抑制剂可以添加到例如口腔卫生用品，食品和饮料中，然后使用。版权所有（C）2009，JPO＆INPIT

8. 发明专利

JP2007045754A Antibacterial agent, offensive odor-preventing agent, oral hygiene product, dermal hygiene product, cosmetic and food or beverage 有权
标题翻译：抗菌剂，有害气味预防剂，口服卫生用品，德国卫生用品，化妆品和食品或饮料
公开(公告)号：JP2007045754A
公开(公告)日：2007-02-22
申请号：JP2005232431
申请日：2005-08-10
申请人： Pokka Corp , 株式会社ポッカコーポレーション
发明人： FUKUMOTO SHUICHI , GOTO TAKATERU
IPC分类号： A61K36/47 , A23L3/3472 , A23L3/3544 , A23L5/20 , A61K8/00 , A61K8/49 , A61K8/96 , A61K31/353 , A61K36/00 , A61P1/02 , A61P17/00 , A61P31/04 , A61Q11/00 , A61Q15/00
CPC分类号： Y02A50/473
摘要： PROBLEM TO BE SOLVED: To provide an antibacterial agent exhibiting high antibacterial effect, an offensive odor-preventing agent for suppressing body odor and offensive odor caused by microorganisms, an oral hygiene product for making the oral cavity sanitary, a dermal hygiene product for making the skin sanitary, a cosmetic and food and beverage each excellent in shelf life. SOLUTION: The antibacterial agent and offensive odor-preventing agent each comprises an extract of Macaranga tanarius, preferably an extract of Macaranga tanarius with an organic solvent as an active ingredient. The extract of Macaranga tanarius comprises nymphaeol-B,C, preferably nymphaeol-A and/or propolin A in addition to nymphaeol-B,C. The extract with the organic solvent is produced by extracting Macaranga tanarium with an extraction solvent containing an organic solvent such as a lower alcohol as a main ingredient. The oral hygiene product and the dermal hygiene product each comprises the above antibacterial agent as an active ingredient. The cosmetic and the food and the beverage each comprises the above antibacterial agent. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：为了提供具有高抗菌效果的抗菌剂，用于抑制由微生物引起的体臭和异味的防臭气味剂，用于使口腔卫生的口腔卫生产品，真皮卫生产品使皮肤卫生，保质期优良的化妆品和食品和饮料。解决方案：抗菌剂和防臭气味剂各自包含马齿苋（Macaranga tanarius）的提取物，优选为具有有机溶剂作为活性成分的马齿香（Macaranga tanarius）的提取物。马齿苋（Macaranga tanarius）的提取物除了尼莫酚B，C之外，还含有宁波醇B，C，优选尼莫酚-A和/或丙酰胺A. 用有机溶剂的提取物是通过用含有有机溶剂如低级醇作为主要成分的提取溶剂萃取马来加is制得的。口腔卫生用品和皮肤卫生用品均含有上述抗菌剂作为活性成分。化妆品，食品和饮料各自包含上述抗菌剂。版权所有（C）2007，JPO＆INPIT

9. 发明专利

JP2006008783A Antioxidant 有权
标题翻译：抗氧化
公开(公告)号：JP2006008783A
公开(公告)日：2006-01-12
申请号：JP2004185656
申请日：2004-06-23
申请人： Pokka Corp , 株式会社ポッカコーポレーション
发明人： KUMAZAWA SHIGENORI , NAKAYAMA TSUTOMU , ARAGAKI TSUTOMU , FUKUMOTO SHUICHI
IPC分类号： C09K15/34
摘要： PROBLEM TO BE SOLVED: To provide an antioxidant exhibiting high antioxidant activity. SOLUTION: The antioxidant consists of an extract by solvent of Oobagi. Oobagi is also called Macaranga tanarius and an evergreen broad-leaved tree belonging to the Oobagi genus of the Euphorbiaceae family. The above solvent extract is preferably obtained through solvent extraction from a raw material containing the leaf blades or the tips of the stems of Oobagi. As the solvent ethanol is preferred. Since the solvent extract has high antioxidant activity, the antioxidant can prevent degradation of foods/drinks, cosmetics, pharmaceuticals or unregulated medicines to enhance their preservability, or can demonstrate health promotion effect or effect preventing the symptoms of senility by peroral intake or transdermal administration. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供具有高抗氧化活性的抗氧化剂。
解决方案：抗氧化剂由Oobagi的溶剂提取物组成。 Oobagi也被称为马齿苋（Magnaranga tanarius）和属于大戟科（Ouphorbiaceae）的Oobagi属的常绿阔叶树。上述溶剂提取物优选通过从含有叶片的原料或Oobagi茎的尖端进行溶剂萃取而获得。因为溶剂乙醇是优选的。由于溶剂提取物具有高抗氧化活性，因此抗氧化剂可以防止食品/饮料，化妆品，药物或不受管制药物的降解，从而提高它们的保存性，或者可以通过口服摄入或透皮给药来证明健康促进作用或效果来防止衰老症状。版权所有（C）2006，JPO＆NCIPI

10. 发明专利

JP2006008552A Method for producing flavanone compound 有权
标题翻译：生产氟烷酮化合物的方法
公开(公告)号：JP2006008552A
公开(公告)日：2006-01-12
申请号：JP2004185655
申请日：2004-06-23
申请人： Pokka Corp , 株式会社ポッカコーポレーション
发明人： KUMAZAWA SHIGENORI , NAKAYAMA TSUTOMU , ARAGAKI TSUTOMU , FUKUMOTO SHUICHI
IPC分类号： C07D311/32 , A23L1/30 , A61K31/366 , A61K36/47 , A61P31/04 , A61P35/00 , A61P39/06
摘要： PROBLEM TO BE SOLVED: To provide a method for easily producing a flavanone compound. SOLUTION: The flavanone compound has a structure represented by formula (1), formula (2), formula (3) or formula (4). The method for producing the flavanone compound comprises the step of subjecting Macaranga tanarius as raw material to ethanol extraction and the step of isolating the objective flavanone compound from the resultant extract. In the latter step, it is preferable to use a reverse-phase chromatography with a hydrophobic carrier. COPYRIGHT: (C)2006,JPO&NCIPI

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