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1. 发明申请

US20060147946A1 Novel calcium channel variants and methods of use thereof 审中-公开
标题翻译：新型钙通道变体及其使用方法
公开(公告)号：US20060147946A1
公开(公告)日：2006-07-06
申请号：US11051725
申请日：2005-01-27
申请人： Pinchas Akiva , Alexander Dlber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekhari , Zipi Shaged , Moshe Olshansky , Arial Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad Cojocaru , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanquing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
发明人： Pinchas Akiva , Alexander Dlber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekhari , Zipi Shaged , Moshe Olshansky , Arial Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad Cojocaru , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanquing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
IPC分类号： C12Q1/68 , C07H21/04 , C12P21/06 , C07K14/705
CPC分类号： C07K14/705 , G16B25/00 , G16B30/00 , G16B50/00
摘要： Novel alpha 1 subunit splice variants, including nucleic and amino acid sequences. Methods of use thereof are also described.
摘要翻译：新的α1亚基剪接变体，包括核酸和氨基酸序列。还描述了其使用方法。

2. 发明申请

US20060068405A1 Methods and systems for annotating biomolecular sequences 审中-公开
标题翻译：注释生物分子序列的方法和系统
公开(公告)号：US20060068405A1
公开(公告)日：2006-03-30
申请号：US11043860
申请日：2005-01-27
申请人： Alex Diber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekharia , Zipi Shaked , Moshe Olshansky , Ariel Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad Cojocaru , Pinchas Akiva , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanqing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
发明人： Alex Diber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekharia , Zipi Shaked , Moshe Olshansky , Ariel Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad Cojocaru , Pinchas Akiva , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanqing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
IPC分类号： C12Q1/68 , G06F19/00
CPC分类号： C07K14/705 , G16B25/00 , G16B30/00 , G16B50/00
摘要： Polypeptide sequences and polynucleotide sequences are provided. Also provided are annotative information concerning such sequences and uses for these sequences.
摘要翻译：提供多肽序列和多核苷酸序列。还提供了关于这些序列的这些序列和用途的注释信息。

3. 发明申请

US20110091454A1 METHODS AND SYSTEMS FOR ANNOTATING BIOMOLECULAR SEQUENCES 审中-公开
标题翻译：生物分子序列的方法和系统
公开(公告)号：US20110091454A1
公开(公告)日：2011-04-21
申请号：US12701651
申请日：2010-02-08
申请人： Alex Diber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekharia , Zipi Shaked , Moshe Olshansky , Ariel Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad S. Cojocaru , Pinchas Akiva , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanqing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
发明人： Alex Diber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekharia , Zipi Shaked , Moshe Olshansky , Ariel Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad S. Cojocaru , Pinchas Akiva , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanqing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
IPC分类号： A61K39/395 , C07K16/00 , G01N33/53 , A61P35/00
CPC分类号： C07K14/705 , G16B25/00 , G16B30/00 , G16B50/00
摘要： Polypeptide sequences and polynucleotide sequences are provided. Also provided are annotative information concerning such sequences and uses for these sequences.
摘要翻译：提供多肽序列和多核苷酸序列。还提供了关于这些序列的这些序列和用途的注释信息。

4. 发明申请

US20050009771A1 Methods and systems for identifying naturally occurring antisense transcripts and methods, kits and arrays utilizing same 审中-公开
标题翻译：用于鉴定天然存在的反义转录物的方法和系统以及使用其的方法，试剂盒和阵列
公开(公告)号：US20050009771A1
公开(公告)日：2005-01-13
申请号：US10764503
申请日：2004-01-27
申请人： Erez Levanon , Jeanne Bernstein , Sarah Pollock , Alex Diber , Zurit Levine , Sergey Nemzer , Vladimir Grebinsky , Hanqing Xie , Brian Meloon , Andrew Olson , Dvir Dahary , Yossi Cohen , Avi Shoshan , Shira Walach , Alon Wasserman , Rami Khosravi , Galit Rotman
发明人： Erez Levanon , Jeanne Bernstein , Sarah Pollock , Alex Diber , Zurit Levine , Sergey Nemzer , Vladimir Grebinsky , Hanqing Xie , Brian Meloon , Andrew Olson , Dvir Dahary , Yossi Cohen , Avi Shoshan , Shira Walach , Alon Wasserman , Rami Khosravi , Galit Rotman
IPC分类号： A61K48/00 , C12N20060101 , C12N15/11 , C12Q1/68 , G01N33/48 , G01N33/50 , G06F19/00
CPC分类号： C12Q1/6876 , C12N15/111 , C12N2310/11 , C12N2320/11 , C12N2330/10 , C12Q2600/136 , C12Q2600/158 , G16B30/00 , Y02A50/58 , Y02A90/26
摘要： A method of identifying putative naturally occurring antisense transcripts is provided. The method is effected by (a) computationally aligning a first database including sense-oriented polynucleotide sequences with a second database including expressed polynucleotide sequences; and (b) identifying expressed polynucleotide sequences from the second database being capable of forming a duplex with at least one sense-oriented polynucleotide sequence of the first database, thereby identifying putative naturally occurring antisense transcripts. Also provided are polynucleotides and polypeptide sequences identified by the above-described methodology.
摘要翻译：提供了鉴定推定的天然存在的反义转录物的方法。该方法通过以下步骤来实现：（a）计算对齐包含有意向多核苷酸序列的第一数据库与包括表达的多核苷酸序列的第二数据库; 和（b）从第二数据库鉴定表达的多核苷酸序列能够与第一数据库的至少一个有义向多核苷酸序列形成双链体，从而鉴定推定的天然存在的反义转录物。还提供了通过上述方法鉴定的多核苷酸和多肽序列。

5. 发明授权

US08812672B2 Method and system for managing and distributing digital media 有权
标题翻译：管理和分发数字媒体的方法和系统
公开(公告)号：US08812672B2
公开(公告)日：2014-08-19
申请号：US11499768
申请日：2006-08-07
申请人： Alan Ramaley , Andrew Sodt , Rahul Sonnad , Ian Blaine , Andrew Olson
发明人： Alan Ramaley , Andrew Sodt , Rahul Sonnad , Ian Blaine , Andrew Olson
IPC分类号： G06F15/173
CPC分类号： H04L65/60 , G06F3/0481 , G06F3/04842 , H04L29/06027 , H04L67/2823 , H04L69/329
摘要： A system and method that integrates a plurality of media service systems offering different multimedia services such as media storage, syndication, delivery, and billing services. The system and method also provides automated file transcoding. In embodiment, a method of the present invention includes receiving a plurality of physical media files, organizing the plurality of physical media files so that different bit-rates and formats of a single source material are organized into a media database entity, receiving user specified delivery settings for the distribution of the physical media file, generating a release database entity storing the delivery settings of the physical media file, generating an address indicating the storage location of the release, and transmitting the address to a remote computing device.
摘要翻译：集成了提供不同多媒体服务的多个媒体服务系统的媒体存储，联合，传送和计费服务的系统和方法。系统和方法还提供自动文件转码。在实施例中，本发明的方法包括接收多个物理媒体文件，组织多个物理媒体文件，使得单个源素材的不同比特率和格式被组织到媒体数据库实体中，接收用户指定的传送用于分发物理媒体文件的设置，生成存储物理媒体文件的传送设置的发行数据库实体，生成指示释放的存储位置的地址，以及将地址发送到远程计算设备。

6. 发明申请

US20120260392A1 KNEE PAD 审中-公开
标题翻译：护膝
公开(公告)号：US20120260392A1
公开(公告)日：2012-10-18
申请号：US13447182
申请日：2012-04-14
申请人： Thomas Votel , Andrew Olson , Dominique P. Aris
发明人： Thomas Votel , Andrew Olson , Dominique P. Aris
IPC分类号： A41D13/06
CPC分类号： A41D13/065
摘要： Disclosed are knee pad assemblies, methods and systems comprising a knee pad base and an outer cover that forms the contacting surface of the knee pad. A removable cover may be secured to a knee pad base. Replacement cover configurations may be provided that are adapted to various surfaces, including roofing, tile, wood, carpet, concrete and asphalt. The knee pad base can be adapted for different user weights and durations for wearing the pad. The outer cover can provide a floating suspension. The knee pad base may be held in place on knee of the user by various mechanisms. The restraint mechanisms can be adjusted by the user. The knee pad assembly can also include a tension/release mechanism so that strap tension is decreased or released when kneeling but increases tension or engage when the user stands to retain the knee pad in the desired location.
摘要翻译：披露的是膝盖垫组件，方法和系统，其包括形成膝盖垫的接触表面的膝盖垫基座和外盖。可移除的盖可以固定到膝盖垫基座。可以提供适于各种表面的替换盖构造，包括屋面，瓦，木，地毯，混凝土和沥青。膝垫底座可适用于不同的使用者重量和穿戴垫的持续时间。外盖可以提供浮动悬挂。膝盖垫基座可以通过各种机构保持在使用者的膝盖上的适当位置。约束机构可由用户进行调整。膝盖垫组件还可以包括张力/释放机构，使得当跪下时皮带张力减小或释放，但是当使用者站立以将膝盖保持在期望位置时增加张力或接合。

7. 发明申请

US20070215834A1 FLEXIBLE SEATS FOR PROCESS CONTROL VALVES 有权
标题翻译：用于过程控制阀的柔性座椅
公开(公告)号：US20070215834A1
公开(公告)日：2007-09-20
申请号：US11741258
申请日：2007-04-27
申请人： Wade Helfer , David Koester , Benjamin Good , Paul Dalluge , Andrew Olson
发明人： Wade Helfer , David Koester , Benjamin Good , Paul Dalluge , Andrew Olson
IPC分类号： F16K1/42
CPC分类号： F16K1/2261 , F16K1/2266
摘要： Flexible seals for process control valves are disclosed. An example disclosed seal includes a seal for use with a butterfly valve. The example seal includes a substantially flexible ring-shaped carrier configured to be fixed within the butterfly valve and to surround a flow control aperture therein. Additionally, the seal includes a ring-shaped cartridge coupled to an inner diameter of the ring-shaped carrier. The cartridge includes a first portion and a second portion coupled to the first portion to define a circumferential opening to hold a seal ring.
摘要翻译：公开了用于过程控制阀的柔性密封件。所公开的密封件包括用于与蝶形阀一起使用的密封件。示例性密封件包括基本上柔性的环形载体，其构造成固定在蝶形阀内并围绕其中的流量控制孔。此外，密封件包括联接到环形载体的内径的环形筒。盒包括第一部分和第二部分，其联接到第一部分以限定用于保持密封环的周向开口。

8. 发明申请

US20050089887A1 Novel human ion channel proteins 审中-公开
标题翻译：新型人类离子通道蛋白
公开(公告)号：US20050089887A1
公开(公告)日：2005-04-28
申请号：US10862110
申请日：2004-06-04
申请人： Alexander Turner , Andrew Olson , Brian Zambrowicz , Glenn Friedrich , Arthur Sands
发明人： Alexander Turner , Andrew Olson , Brian Zambrowicz , Glenn Friedrich , Arthur Sands
IPC分类号： A01K67/027 , A61K31/711 , A61K35/76 , A61K38/00 , A61K39/395 , A61K48/00 , A61P25/00 , A61P43/00 , C07K14/47 , C07K14/705 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12Q1/02 , G01N33/15 , G01N33/50 , C12Q1/68 , C07H21/04 , C12N15/85
CPC分类号： C07K14/705 , A01K2217/05
摘要： The present invention provides a novel family of human ion channel proteins (ICPs). The invention additionally provides for agonists, antagonists, antibodies, antisense molecules that are specific for the ICPs, and further provides genetically engineered expression vectors for the ICPs and host cells comprising the same. The invention further provides for processes for identifying/producing molecules that effect ICP activity that comprise the use of the disclosed ICPs or genes encoding the same.
摘要翻译：本发明提供了一种新的人离子通道蛋白家族（ICP）。本发明另外提供对ICP具有特异性的激动剂，拮抗剂，抗体，反义分子，并进一步提供用于ICP和包含该ICP的宿主细胞的基因工程表达载体。本发明进一步提供用于鉴定/产生影响ICP活性的分子的方法，其包括使用所公开的ICP或编码其的基因。

9. 发明申请

US20080003673A1 Novel human proteases and polynucleotides encoding the same 审中-公开
标题翻译：新型人类蛋白酶和编码相同的多核苷酸
公开(公告)号：US20080003673A1
公开(公告)日：2008-01-03
申请号：US11220398
申请日：2005-09-06
申请人： Alejandro Abuin , Gregory Donoho , Carl Friddle , Glenn Friedrich , Brenda Gerhardt , Erin Hilbun , Yi Hu , James Kieke , Maricar Miranda , Michael Nehls , Boris Nepomnichy , Andrew Olson , Arthur Sands , John Scoville , C. Turner , D. Walke , Nathaniel Wilganowski , Xuanchuan Yu , Brian Zambrowicz
发明人： Alejandro Abuin , Gregory Donoho , Carl Friddle , Glenn Friedrich , Brenda Gerhardt , Erin Hilbun , Yi Hu , James Kieke , Maricar Miranda , Michael Nehls , Boris Nepomnichy , Andrew Olson , Arthur Sands , John Scoville , C. Turner , D. Walke , Nathaniel Wilganowski , Xuanchuan Yu , Brian Zambrowicz
IPC分类号： C12N15/00 , C07H21/04 , C07K1/00
CPC分类号： C12N9/6421
摘要： Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
摘要翻译：公开了可用于治疗，诊断和药物基因组应用的新型人多核苷酸和多肽序列。

10. 发明授权

US07089309B2 Method and system for managing and distributing digital media 有权
公开(公告)号：US07089309B2
公开(公告)日：2006-08-08
申请号：US09898430
申请日：2001-07-02
申请人： Alan Ramaley , Andrew Sodt , Rahul Sonnad , Ian Blaine , Andrew Olson
发明人： Alan Ramaley , Andrew Sodt , Rahul Sonnad , Ian Blaine , Andrew Olson
IPC分类号： G06F15/173
CPC分类号： H04L65/60 , G06F3/0481 , G06F3/04842 , H04L29/06027 , H04L67/2823 , H04L69/329
摘要： A system and method that integrates a plurality of media service systems offering different multimedia services such as media storage, syndication, delivery, and billing services. The system and method also provides automated file transcoding. In embodiment, a method of the present invention includes receiving a plurality of physical media files, organizing the plurality of physical media files so that different bit-rates and formats of a single source material are organized into a media database entity, receiving user specified delivery settings for the distribution of the physical media file, generating a release database entity storing the delivery settings of the physical media file, generating an address indicating the storage location of the release, and transmitting the address to a remote computing device.

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