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1. 发明授权

US09737666B2 Assembly for a drug delivery device and drug delivery device 有权
公开(公告)号：US09737666B2
公开(公告)日：2017-08-22
申请号：US13504296
申请日：2010-11-01
申请人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Bruggemann , Brice Ulrich Tchouadje , Kevin Igor Youmbi Ngatchou
发明人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Bruggemann
IPC分类号： A61M5/315 , A61M5/24
CPC分类号： A61M5/31535 , A61M5/24 , A61M5/31555 , A61M5/31556 , A61M5/31585 , A61M2005/2407 , A61M2205/581 , A61M2205/582
摘要： An assembly for a drug delivery device is disclosed. An example assembly includes a housing, a rotation member, a drive member, and at least one correction member. The rotation member is adapted to be rotated with respect to the housing in a first rotational direction for delivering a dose of a drug. The drive member is coupleable to the rotation member for delivering the dose. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in the first rotational direction due to mechanical interaction of the rotation member and the drive member. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member.

2. 发明申请

US20130046247A1 Assembly for a Drug Delivery Device and Drug Delivery Device 有权
标题翻译：药物输送装置和药物输送装置的装配
公开(公告)号：US20130046247A1
公开(公告)日：2013-02-21
申请号：US13504296
申请日：2010-11-01
申请人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Bruggemann
发明人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Bruggemann
IPC分类号： A61M5/315 , A61M5/31
CPC分类号： A61M5/31535 , A61M5/24 , A61M5/31555 , A61M5/31556 , A61M5/31585 , A61M2005/2407 , A61M2205/581 , A61M2205/582
摘要： An assembly for a drug delivery device (1) comprises a housing (5), a rotation member (15), a drive member (16) and at least one correction member (7). The rotation member (15) is adapted to be rotated with respect to the housing (5) in a first rotational direction for delivering a dose of a drug (11). The drive member (16) is coupleable to the rotation member (15) for delivering the dose. In a delivery mode, the drive member (16) and the rotation member (15) are coupled such that the drive member (16) follows rotational movement of the rotation member (15) in the first rotational direction due to mechanical interaction of the rotation member (15) and the drive member (16). In a correction mode, the rotation member (15) and the drive member (16) are decoupled such that the rotation member (15) is rotatable in the first rotational direction with respect to the drive member (16). For switching from the delivery mode into the correction mode, the correction member (7) is movable with respect to the housing (5), wherein the assembly is configured such that movement of the correction member (7) with respect to the housing (5) is converted into a relative movement between the drive member (16) and the rotation member (15) for decoupling the drive member (16) and the rotation member (15).
摘要翻译：用于药物输送装置（1）的组件包括壳体（5），旋转构件（15），驱动构件（16）和至少一个校正构件（7）。旋转构件（15）适于在第一旋转方向上相对于壳体（5）旋转以递送药物（11）的剂量。驱动构件（16）可与旋转构件（15）耦合以输送剂量。在传送模式中，驱动构件（16）和旋转构件（15）联接成使得驱动构件（16）由于旋转构件（15）的旋转的机械相互作用而沿第一旋转方向旋转运动构件（15）和驱动构件（16）。在校正模式中，旋转构件（15）和驱动构件（16）被解耦，使得旋转构件（15）能够相对于驱动构件（16）沿第一旋转方向旋转。为了从传送模式切换到校正模式，校正构件（7）能够相对于壳体（5）移动，其中组件被构造成使得校正构件（7）相对于壳体（5）的移动）被转换成驱动构件（16）和旋转构件（15）之间的相对运动，用于使驱动构件（16）和旋转构件（15）分离。

3. 发明申请

US20130226091A1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 有权
标题翻译：用于药物递送装置和药物递送装置的驱动机构
公开(公告)号：US20130226091A1
公开(公告)日：2013-08-29
申请号：US13883393
申请日：2011-11-11
申请人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Brüggemann
发明人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Brüggemann
IPC分类号： A61M5/142
CPC分类号： A61M5/31585 , A61M5/31511 , A61M5/31515 , A61M5/31525 , A61M5/31528 , A61M5/31533 , A61M5/31565 , A61M5/31571 , A61M5/31583
摘要： The drive mechanism comprises a piston rod, a dose member with a thread engaging a corresponding thread of the body to allow a helical movement of the dose member with respect to the body, a drive sleeve rotationally coupled to the dose member, and stop means provided to restrict or inhibit a movement of the drive sleeve in the proximal direction and in the distal direction with respect to the body, the drive sleeve and the piston rod being unidirectionally coupled.
摘要翻译：驱动机构包括活塞杆，剂量构件，其具有接合主体的相应螺纹的螺纹，以允许剂量构件相对于主体的螺旋运动，旋转地联接到剂量构件的驱动套筒和设置的止动装置以限制或抑制驱动套筒相对于主体在近端方向和远侧方向上的移动，驱动套筒和活塞杆单向联接。

4. 发明申请

US20120265151A1 Resettable Drive Mechanism for a Medication Delivery Device and Medication Delivery Device 有权
标题翻译：药物输送装置和药物输送装置的可复位驱动机构
公开(公告)号：US20120265151A1
公开(公告)日：2012-10-18
申请号：US13133933
申请日：2009-12-09
申请人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
发明人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
IPC分类号： A61M5/315
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/31511 , A61M5/31515 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31555 , A61M5/31556 , A61M5/31558 , A61M5/3156 , A61M5/31561 , A61M5/3157 , A61M5/31575 , A61M5/3158 , A61M5/31581 , A61M5/31585 , A61M5/31593 , A61M2005/2407 , A61M2005/3152 , A61M2205/581 , A61M2205/582
摘要： A resettable drive mechanism for a medication delivery device is proposed, said mechanism comprising a housing (13, 17, 40) with a proximal end and a distal end, a drive member (20) rotatable with respect to the housing in a second direction for delivering a dose of a medication, a piston rod (12) adapted to be driven in a distal direction with respect to the housing by the drive member, when the drive member rotates in the second direction, a stop member (26) adapted to prevent rotation of the drive member in a first direction opposite to the second direction with respect to the housing, when the stop member engages the drive member, and a clutch member (58) movable with respect to the housing between a delivery position (D) and a reset position (R), wherein, when the clutch member is in the delivery position, the stop member and the drive member are engaged and the drive member is prevented from rotating in the first direction with respect to the housing, and when the clutch member is in the reset position, the drive member and the stop member are disengaged, the drive member is rotatable in the first direction with respect to the housing and the piston rod is movable in the proximal direction with respect to the housing. Furthermore, a medication delivery device is provided.
摘要翻译：提出了一种用于药物输送装置的可重置驱动机构，所述机构包括具有近端和远端的壳体（13,17,40），驱动构件（20）可相对于壳体沿第二方向旋转，递送一定剂量的药物;活塞杆（12），其适于在所述驱动构件沿所述第二方向旋转时相对于所述壳体在远端方向上被所述驱动构件驱动;止动构件（26），适于防止当所述止动构件接合所述驱动构件时，所述驱动构件在与所述第二方向相反的第一方向上相对于所述壳体旋转;以及离合器构件，所述离合器构件能够相对于所述壳体在输送位置（D）和复位位置（R），其中，当离合器构件处于输送位置时，止动构件和驱动构件接合，并且防止驱动构件相对于壳体沿第一方向旋转，并且当离合器会员我所述驱动构件和所述止动构件脱离接合，所述驱动构件能够相对于所述壳体沿所述第一方向旋转，并且所述活塞杆可相对于所述壳体沿近侧方向移动。此外，提供了药物输送装置。

5. 发明申请

US20120095413A1 Drive Mechanism for a Medication Delivery Device and Medication Delivery Device 有权
标题翻译：药物输送装置和药物输送装置的驱动机构
公开(公告)号：US20120095413A1
公开(公告)日：2012-04-19
申请号：US13133884
申请日：2009-12-09
申请人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
发明人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
IPC分类号： A61M5/315
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/3148 , A61M5/31511 , A61M5/31515 , A61M5/31528 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31543 , A61M5/31555 , A61M5/31556 , A61M5/31558 , A61M5/3156 , A61M5/31561 , A61M5/3157 , A61M5/31575 , A61M5/3158 , A61M5/31581 , A61M5/31585 , A61M5/31593 , A61M2005/2407 , A61M2005/3152 , A61M2205/581 , A61M2205/582 , F16H25/12 , F16H25/20 , F16H31/001 , Y10T74/18568 , Y10T74/18696
摘要： A drive mechanism for a medication delivery device (1) is proposed, the drive mechanism comprising a housing (13, 17, 40) having a proximal end and a distal end, a rotation member (21) which is adapted to be rotated in a first direction with respect to the housing during setting of a dose of a medication and to be rotated in a second direction with respect to the housing during delivery of the dose, the second direction being opposite to the first direction, a piston rod (12) which is adapted to be displaced in a distal direction with respect to the housing for delivering the dose, a drive member (20) which follows rotational movement of the rotation member in the second direction during delivery of the dose, and a stop member (26) which prevents rotational movement of the drive member with respect to the housing in the first direction during setting of the dose, wherein the rotational movement of the drive member in the second direction is converted into movement of the piston rod in the distal direction with respect to the housing. Furthermore, a medication delivery device is provided for.
摘要翻译：提出了一种用于药物输送装置（1）的驱动机构，所述驱动机构包括具有近端和远端的壳体（13,17,40），旋转构件（21），其适于在第一方向相对于壳体在设置药物剂量期间相对于壳体在第二方向上相对于壳体在剂量递送期间旋转，第二方向与第一方向相反，活塞杆（12）其适于相对于用于输送剂量的壳体在远端方向上移位;驱动构件（20），其在所述剂量递送期间沿所述旋转构件沿所述第二方向旋转运动;以及止动构件（26）），其在剂量设定期间防止驱动构件相对于壳体在第一方向上的旋转运动，其中驱动构件在第二方向上的旋转运动转换为活塞杆的运动相对于壳体的远端方向。此外，提供了一种药物输送装置。

6. 发明授权

US09393368B2 Drive mechanism for a drug delivery device and drug delivery device 有权
标题翻译：用于药物递送装置和药物递送装置的驱动机构
公开(公告)号：US09393368B2
公开(公告)日：2016-07-19
申请号：US13883393
申请日：2011-11-11
申请人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Brüggemann
发明人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Brüggemann
IPC分类号： A61M5/315
CPC分类号： A61M5/31585 , A61M5/31511 , A61M5/31515 , A61M5/31525 , A61M5/31528 , A61M5/31533 , A61M5/31565 , A61M5/31571 , A61M5/31583
摘要： The drive mechanism comprises a piston rod, a dose member with a thread engaging a corresponding thread of the body to allow a helical movement of the dose member with respect to the body, a drive sleeve rotationally coupled to the dose member, and stop means provided to restrict or inhibit a movement of the drive sleeve in the proximal direction and in the distal direction with respect to the body, the drive sleeve and the piston rod being unidirectionally coupled.
摘要翻译：驱动机构包括活塞杆，剂量构件，其具有接合主体的相应螺纹的螺纹，以允许剂量构件相对于主体的螺旋运动，旋转地联接到剂量构件的驱动套筒和设置的止动装置以限制或抑制驱动套筒相对于主体在近端方向和远侧方向上的移动，驱动套筒和活塞杆单向联接。

7. 发明授权

US09089652B2 Drive mechanism for a medication delivery device and medication delivery device 有权
标题翻译：药物输送装置和药物输送装置的驱动机构
公开(公告)号：US09089652B2
公开(公告)日：2015-07-28
申请号：US13133884
申请日：2009-12-09
申请人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
发明人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
IPC分类号： A61M5/00 , A61M5/315 , A61M5/24
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/3148 , A61M5/31511 , A61M5/31515 , A61M5/31528 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31543 , A61M5/31555 , A61M5/31556 , A61M5/31558 , A61M5/3156 , A61M5/31561 , A61M5/3157 , A61M5/31575 , A61M5/3158 , A61M5/31581 , A61M5/31585 , A61M5/31593 , A61M2005/2407 , A61M2005/3152 , A61M2205/581 , A61M2205/582 , F16H25/12 , F16H25/20 , F16H31/001 , Y10T74/18568 , Y10T74/18696
摘要： A drive mechanism for a medication delivery device (1) is proposed, the drive mechanism comprising a housing (13, 17, 40) having a proximal end and a distal end, a rotation member (21) which is adapted to be rotated in a first direction with respect to the housing during setting of a dose of a medication and to be rotated in a second direction with respect to the housing during delivery of the dose, the second direction being opposite to the first direction, a piston rod (12) which is adapted to be displaced in a distal direction with respect to the housing for delivering the dose, a drive member (20) which follows rotational movement of the rotation member in the second direction during delivery of the dose, and a stop member (26) which prevents rotational movement of the drive member with respect to the housing in the first direction during setting of the dose, wherein the rotational movement of the drive member in the second direction is converted into movement of the piston rod in the distal direction with respect to the housing. Furthermore, a medication delivery device is provided for.
摘要翻译：提出了一种用于药物输送装置（1）的驱动机构，所述驱动机构包括具有近端和远端的壳体（13,17,40），旋转构件（21），其适于在第一方向相对于壳体在设置药物剂量期间相对于壳体在第二方向上相对于壳体在剂量递送期间旋转，第二方向与第一方向相反，活塞杆（12）其适于相对于用于输送剂量的壳体在远端方向上移位;驱动构件（20），其在所述剂量递送期间沿所述旋转构件沿所述第二方向旋转运动;以及止动构件（26）），其在剂量设定期间防止驱动构件相对于壳体在第一方向上的旋转运动，其中驱动构件在第二方向上的旋转运动转换为活塞杆的运动相对于壳体的远端方向。此外，提供了一种药物输送装置。

8. 发明授权

US08968258B2 Resettable drive mechanism for a medication delivery device and medication delivery device 有权
标题翻译：用于药物输送装置和药物输送装置的可重置驱动机构
公开(公告)号：US08968258B2
公开(公告)日：2015-03-03
申请号：US13133933
申请日：2009-12-09
申请人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
发明人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
IPC分类号： A61M5/315 , A61M5/24
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/31511 , A61M5/31515 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31555 , A61M5/31556 , A61M5/31558 , A61M5/3156 , A61M5/31561 , A61M5/3157 , A61M5/31575 , A61M5/3158 , A61M5/31581 , A61M5/31585 , A61M5/31593 , A61M2005/2407 , A61M2005/3152 , A61M2205/581 , A61M2205/582
摘要： A resettable drive mechanism for a medication delivery device comprising a housing and a drive member rotatable in a second direction for delivering a dose. A piston rod driven distally when a drive member rotates in the second direction. A stop member prevents rotation of the drive member in a first direction opposite the second direction, when the stop member engages the drive member. A clutch member is movable between a delivery and reset position. When the clutch member is in the delivery position, the stop member and the drive member engage and the drive member is prevented from rotating in the first direction. When the clutch member is in the reset position, the drive member and the stop member disengage. The drive member is rotatable in the first direction.
摘要翻译：一种用于药物输送装置的可重置驱动机构，包括壳体和可沿第二方向旋转的用于递送剂量的驱动构件。当驱动构件沿第二方向旋转时，活塞杆向远侧驱动。当止动构件接合驱动构件时，止动构件防止驱动构件沿与第二方向相反的第一方向旋转。离合器构件可在输送和复位位置之间移动。当离合器构件处于排出位置时，停止构件和驱动构件接合，并且防止驱动构件沿第一方向旋转。当离合器构件处于复位位置时，驱动构件和止动构件脱开。驱动构件可沿第一方向旋转。

9. 发明授权

US09974906B2 Assembly for a drug delivery device and drug delivery device 有权
公开(公告)号：US09974906B2
公开(公告)日：2018-05-22
申请号：US15370916
申请日：2016-12-06
申请人： Sanofi-Aventis Deutschland GmbH , Kevin Igor Youmbi Ngatchou
发明人： Philippe Bertrand Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Bruggemann
IPC分类号： A61M5/31 , A61M5/315 , A61M5/24
CPC分类号： A61M5/31535 , A61M5/24 , A61M5/31555 , A61M5/31556 , A61M5/31585 , A61M2005/2407 , A61M2205/581 , A61M2205/582
摘要： An assembly for a drug delivery device comprises a housing, a rotation member, a drive member and at least one correction member. The rotation member is adapted to be rotated with respect to the housing in a first rotational direction for delivering a dose of a drug. The drive member is coupleable to the rotation member for delivering the dose. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in the first rotational direction due to mechanical interaction of the rotation member and the drive member. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member.

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