专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP0328303A3 Acidic polycyclic ether antibiotic having anticoccidial and growth promotant activity 失效
标题翻译：具有抗焦虑和生长激素活性的酸性多环醚类抗生素
公开(公告)号：EP0328303A3
公开(公告)日：1990-03-28
申请号：EP89301017.3
申请日：1989-02-02
申请人： PFIZER INC.
发明人： Dirlam, John Philip , Cullen, Walter Patrick , Maeda, Hiroshi , Tone, Junsuke
IPC分类号： C07H17/04 , C07D493/10 , C12P19/58 , C12P17/06 , A61K31/70 , A61K31/35 , A23K1/17
CPC分类号： C07D493/10 , C12P17/06 , C12R1/03
摘要： An acidic polycyclic ether antibiotic, having structure established by X-ray crystallography, is formed by fermentation of a novel microorganism, Actinomadura sp. ATCC 53708. This novel antibiotic is useful as an anticoccidial in chickens, in the prevention or treatment of swine dysentery, and as a growth promotant in cattle and swine.

2. 发明授权

EP0094176B1 Macrolide antibiotics from streptomyces 有权
标题翻译：来自STREPTOMYCES的MACROLIDE抗生素
公开(公告)号：EP0094176B1
公开(公告)日：1985-08-21
申请号：EP83302403.7
申请日：1983-04-28
申请人： PFIZER INC.
发明人： Celmer, Walter Daniel , Cullen, Walter Patrick , Shibakawa, Riichiro , Tone, Junsuke
IPC分类号： C07H17/08 , A61K31/70 , C12P19/62
CPC分类号： C07H17/08 , C12P19/62 , C12R1/47

3. 发明公开

EP0001720A3 A polycyclic ether antibiotic, process for producing it and its use for controlling coccidiosis and improving feed utilisation in animals 失效
标题翻译：多环素抗生素，其生产方法及其用于控制结核病和改善动物饲料利用的方法
公开(公告)号：EP0001720A3
公开(公告)日：1979-05-16
申请号：EP78300541
申请日：1978-10-25
申请人： Pfizer Inc.
发明人： Celmer, Walter Daniel , Cullen, Walter Patrick , Moppett, Charles Edward , Oscarson, John Richard , Huang, Liang Hsiung , Shibakawa, Riichiro , Tone, Junsuke
IPC分类号： C12D09/14 , C07G11/00 , A61K35/66
CPC分类号： C07G11/00 , Y10S435/886
摘要： The invention provides a novel polycyclic ether antibiotic produced by the micro-organism Streptomyces hygroscopicus ATCC 31337. The novel antibiotic is designated Compound 47,224 and is characterised by solubility, melting point, optical rotation, elemental analysis and ultra-violet and infra-red absorption spectra. It is described as being useful for controlling coccidiosis in poultry by administration in the diet, and for improving feed utilisation in ruminants and monogastric animals.
摘要翻译：本发明提供了由微生物吸水链霉菌链霉菌ATCC 31337产生的新型多环醚抗生素。该抗生素被命名为化合物47,224，其特征在于溶解度，熔点，旋光度，元素分析和紫外和红外吸收光谱。被描述为可用于通过在饮食中施用来控制家禽中的球虫病，并且用于提高反刍动物和单胃动物的饲料利用率。

4. 发明公开

EP0000258A1 Polycyclic ether antibiotics, process for producing them and animal feed compositions containing them 失效
标题翻译：多环醚抗菌素，其制备方法和含有饲料物质。
公开(公告)号：EP0000258A1
公开(公告)日：1979-01-10
申请号：EP78300057.3
申请日：1978-06-20
申请人： PFIZER INC.
发明人： Celmer, Walter Daniel , Cullen, Walter Patrick , Moppett, Charles Edward , Oscarson, John Richard , Huang, Liang Hsiung , Shibakawa, Riichiro , Tone, Junsuke
IPC分类号： C12P1/06 , C07G11/00 , A61K35/66
CPC分类号： C07G11/00 , Y10S435/826
摘要： Antibiotics 47,433 and 47,434 are produced by culture of Actinomycete micro-organism ATCC 31286, and are useful for controlling coccidiosis in poultry by administration in the diet, and for improving feed utilisation in ruminants and monogastric animals.
Antibiotic 47,433 as crystalline free acid is soluble in methanol, acetone, chloroform, methylisobutyl ketone, ethyl acetate and insoluble in water; m.p. 89-99°C; (a)D = +16° (C= 1 . 0 , MeOH); average composition by weight: 64.92% carbon, 9.73% hydrogen and 25.35% oxygen (by difference); infrared absorption (KBr pellets, in microns):2.87,3.42, 5.77, 6.85, 7.30. 8.05, 8.60, 9.20, 10.15, 10.53 and 11.45; following crystalline salts are described: -Na(m.p. 226-32°; (a)D --0.2° (C=1.0, MeOH), -K (m.p. 202.-5°; (α) D = -3.2 (C=1.0, MeOH), -Ag (m.p. 180-2°: (α) D = +3.6° (C=1.0, MeOH). Antibiotic 47.434 as crystalline sodium salt is soluble in chloroform, ethyl acetate, methylisobutyl ketone and insoluble in water; m.p. 230-238°C, (α) D = -1.3° (C-1.0, MeOH); infra-red absorption (KBr pellets, in microns): 3.40, 6.40, 6.85, 7.14, 7.27, 7.75, 8.05, 8.40, 8.62, 9.10, 9.40,10.07, 10.50, 11.49.12.65 and 13.25.
摘要翻译：抗生素47.433和47.434由ATCC 31286放线菌微生物的培养物中产生，并且是用于在饮食控制由管理在家禽球虫病，以及用于反刍动物和单胃动物提高饲料利用率。 ... 抗生素47.433结晶游离酸可溶于甲醇，丙酮，氯仿，甲基异丁基酮，乙酸乙酯和不溶于水; 熔点 89-99℃; （阿尔法）D = 16°（C = 1.0，甲醇）; 平均组成按重量计：64.92％的碳，9.73％的氢和25.35％的氧气（通过差）; 红外吸收（KBr压片，在微米）：2.87，3.42 5.77，6.85，7.30，8时05分，8.60，9.20，15.10，十点53和11时45; 以下的结晶盐描述：-Na（熔点226-32°（阿尔法）D = -0.2°（C = 1.0，甲醇）-K（熔点202 DEG-5（阿尔法）D = -3.2（C = 1.0，甲醇）-Ag（熔点180-2°（阿尔法）D = 3.6°（C = 1.0，甲醇）抗生素47434作为结晶钠盐可溶于氯仿，乙酸乙酯，甲基异丁基酮和不溶性的。水;熔点230-238℃，（阿尔法）D = -1.3°（C = 1.0，甲醇）;红外吸收（KBr压片，在微米）：3.40 6.40，6.85，7.14，7.27，7.75，8点05分，8.40，8.62，9.10，9时40分，10时07分，10:50 11时49分，12.65和13.25。

5. 发明授权

EP0317231B1 An acidic polycyclic ether useful as an anticoccidial agent and as a growth promotant 失效
标题翻译：作为抗焦虑剂和作为生长促进剂的酸性多环化合物
公开(公告)号：EP0317231B1
公开(公告)日：1993-07-21
申请号：EP88310717.9
申请日：1988-11-14
申请人： PFIZER INC.
发明人： Dirlam, John Philip , Cullen, Walter Patrick , Tone, Junsuke , Maeda, Hiroshi
IPC分类号： C07D493/10 , A61K31/35 , C12P17/06 , A23K1/17
CPC分类号： C07H19/01 , A23K20/195 , Y10S435/825

6. 发明公开

EP0153128A3 Novel acidic polycyclic ether antibiotic 有权
标题翻译：新型酸性多环酸抗生素
公开(公告)号：EP0153128A3
公开(公告)日：1987-01-21
申请号：EP85300909
申请日：1985-02-12
申请人： PFIZER INC.
发明人： Celmer, Walter Daniel , Cullen, Walter Patrick , Maeda, Hiroschi , Tone, Junsuke
IPC分类号： C07D493/00 , C12P19/44 , A23K01/17 , C12P19/60 , C12R01/465 , C07D493/10 , C07D311/00 , C07D307/00
CPC分类号： C07H19/01 , A23K20/195 , C12P19/445 , C12P19/60 , C12R1/465 , Y10S435/886
摘要： A new acidic polycyclic ether antibiotic, CP-63,517, having the formula:
and cationic salts thereof produced by submerged aerobic propagation of Streptomyces endus subsp. aureus, ATCC-39574, a new strain of microorganism isolated from a soil sample in Japan, a process for producing this antibiotic and methods for its use to improve feed utilization, promote growth of cattle and swine and to control coccidiosis.

7. 发明授权

EP0000991B1 Antibiotics and pharmaceutical compositions containing them 失效
标题翻译：抗生素和含有它们的药物组合物
公开(公告)号：EP0000991B1
公开(公告)日：1981-11-04
申请号：EP78300252.0
申请日：1978-08-16
申请人： PFIZER INC.
发明人： Celmer, Walter Daniel , Cullen, Walter Patrick , Huang, Liang Hsiung , Jefferson, Mark Tilden , Moppett, Charles Edward , Shibakawa, Riichiro , Tone, Junsuke
IPC分类号： C12P1/06 , A61K35/66 , C07G11/00
CPC分类号： C07G11/00

8. 发明公开

EP0001720A2 A polycyclic ether antibiotic, process for producing it and its use for improving feed utilisation in animals 失效
标题翻译：醚系列，处理其制备方法及其用途，以提高饲料利用率的多环抗生素。
公开(公告)号：EP0001720A2
公开(公告)日：1979-05-02
申请号：EP78300541.6
申请日：1978-10-25
申请人： PFIZER INC.
发明人： Celmer, Walter Daniel , Cullen, Walter Patrick , Moppett, Charles Edward , Oscarson, John Richard , Huang, Liang Hsiung , Shibakawa, Riichiro , Tone, Junsuke
IPC分类号： C12P7/00 , C12R1/55 , C07G11/00 , A61K35/66 , A23K1/17
CPC分类号： C07G11/00 , Y10S435/886
摘要： The invention provides a novel polycyclic ether antibiotic produced by the micro-organism Streptomyces hygroscopicus ATCC 31337. The novel antibiotic is designated Compound 47,224 and is characterised by solubility, melting point, optical rotation, elemental analysis and ultra-violet and infra-red absorption spectra. It is described as being useful for controlling coccidiosis in poultry by administration in the diet, and for improving feed utilisation in ruminants and monogastric animals.
摘要翻译：本发明提供由微生物链霉菌ATCC产生的新颖的多环醚抗菌素31,337th的新型抗生素被指定化合物47.224并且由溶解性，熔点，旋光度，元素分析和紫外光，红外吸收光谱特征的。它被描述为在饮食控制由行政家禽球虫病，并可用于反刍动物和单胃动物提高饲料利用率。

9. 发明公开

EP0317231A3 An acidic polycyclic ether useful as an anticoccidial agent and as a growth promotant 失效
标题翻译：作为抗焦虑剂和作为生长促进剂的酸性聚环氧乙烷
公开(公告)号：EP0317231A3
公开(公告)日：1990-04-18
申请号：EP88310717.9
申请日：1988-11-14
申请人： PFIZER INC.
发明人： Dirlam, John Philip , Cullen, Walter Patrick , Tone, Junsuke , Maeda, Hiroshi
IPC分类号： C07D493/10 , A61K31/35 , C12P17/06 , A23K1/17
CPC分类号： C07H19/01 , A23K20/195 , Y10S435/825
摘要： An acidic polycyclic ether antibiotic, having structure established by X-ray crystallography, is formed by fermentation of a novel microorganism, Actinomadura sp. ATCC 53676. This novel antibiotic is useful as an anticoccidial in chickens and as a growth promotant in cattle and swine.

10. 发明公开

EP0094176A1 Macrolide antibiotics from streptomyces 有权
标题翻译： Makrolide Antibiotika aus Streptomyces。
公开(公告)号：EP0094176A1
公开(公告)日：1983-11-16
申请号：EP83302403.7
申请日：1983-04-28
申请人： PFIZER INC.
发明人： Celmer, Walter Daniel , Cullen, Walter Patrick , Shibakawa, Riichiro , Tone, Junsuke
IPC分类号： C07H17/08 , A61K31/70 , C12P19/62
CPC分类号： C07H17/08 , C12P19/62 , C12R1/47
摘要： A compound of the formula:
or
or a pharmaceutically or veterinaliy acceptable acid addition salt thereof; wherein R 1 is the group of the formula:
and R 2 ist the group of the formula:
their production from the novel microorganism Streptomyces albus subsp. indicus ATCC 39 012, and the novel microorganism itself.
摘要翻译：下式的化合物：... ...或其药学上或兽医学上可接受的酸加成盐;其中R 1是下式基团：... CHEM> ...和R 2是公式：... ...他们从新型微生物链霉菌Streptomyces albus subsp。标本ATCC 39 012和新型微生物本身。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式