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1. 发明申请

US20050032076A1 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES 有权
标题翻译：确定寡核苷酸核苷酸序列和DNA分子的方法
公开(公告)号：US20050032076A1
公开(公告)日：2005-02-10
申请号：US10709436
申请日：2004-05-05
申请人： Peter Williams , Thomas Taylor , Daniel Williams , Ian Gould , Mark Hayes
发明人： Peter Williams , Thomas Taylor , Daniel Williams , Ian Gould , Mark Hayes
IPC分类号： C12N15/09 , C12Q1/68 , C12P19/34
CPC分类号： C12P19/34 , C12Q1/6816 , C12Q1/6869 , C12Q2565/629 , C12Q2533/101 , C12Q2565/301 , C12Q2563/107 , C12Q2563/103
摘要： The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA poly-merase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.
摘要翻译：本发明涉及一种用于分析核酸序列的新方法，该方法基于实时检测将DNA微聚合酶催化的四个核苷酸碱基中的每一个（在微流体系统中单独提供和连续供应）并入到含有模板系统，其包含未知序列的DNA片段和寡核苷酸引物。将核苷酸碱基掺入模板系统可以通过多种方法中的任何一种检测，包括但不限于荧光和化学发光检测。或者，可以使用通过使用热电堆，热敏电阻和折射率测量将核苷酸并入扩展模板系统产生的热的微量热法测定来检测延伸反应。

2. 发明授权

US08480895B2 Vacuum base and related methods and apparatus for vacuum filtration 有权
标题翻译：真空底座及相关方法及真空过滤装置
公开(公告)号：US08480895B2
公开(公告)日：2013-07-09
申请号：US13567522
申请日：2012-08-06
申请人： Thomas Taylor , Jeffrey F. Kane , Vito Lore , Sean Landis Phillips
发明人： Thomas Taylor , Jeffrey F. Kane , Vito Lore , Sean Landis Phillips
IPC分类号： C02F1/00
CPC分类号： B01D29/085 , B01D2201/204 , Y10T29/49826
摘要： Liquid filter assemblies including an upper sample reservoir, a sample filter and a lower storage bottle are supported by a vacuum base. The base has a vacuum inlet port and, for connection to the liquid filter assembly, a vacuum outlet port. A vacuum is provided through the base to below the sample filter to draw sample liquid through the sample filter into the storage bottle. The base may include an auxiliary vacuum outlet port for connection with additional devices. The bases may be connected from one to another through auxiliary vacuum outlets and the vacuum inlets to make a chain of liquid filter assemblies supplied from one vacuum source. Alternatively, one base may include multiple vacuum outlet ports so that it may support and supply vacuum to a plurality of liquid filter assemblies.
摘要翻译：包括上样品容器，样品过滤器和下储存瓶的液体过滤器组件由真空底座支撑。基座具有真空入口，并且用于连接到液体过滤器组件的真空出口。通过底部提供真空至样品过滤器下方，将样品液体通过样品过滤器吸入储存瓶中。基座可以包括用于与附加装置连接的辅助真空出口。底座可以通过辅助真空出口和真空入口从一个连接到另一个，以形成一个从一个真空源供应的液体过滤器组件链。或者，一个基座可以包括多个真空出口端口，使得其可以支撑并提供多个液体过滤器组件的真空。

3. 发明授权

US08231012B2 Filtrate storage system 有权
标题翻译：过滤储存系统
公开(公告)号：US08231012B2
公开(公告)日：2012-07-31
申请号：US12023757
申请日：2008-01-31
申请人： Jeffrey F. Kane , Thomas Taylor , Vito Lore , Sean Landis Phillips
发明人： Jeffrey F. Kane , Thomas Taylor , Vito Lore , Sean Landis Phillips
IPC分类号： B01D35/00
CPC分类号： B01D29/085 , B01D2201/204
摘要： A method of removing a filtrate storage bottle from a water bath includes inserting at least two finger underneath a radially protruding lip of a filtrate storage bottle sealing cap and raising the at least two fingers to lift the bottle from the water bath. A side wall portion of the filtrate storage bottle sealing cap is smaller in perimeter than a circle surrounding the radially protruding lip. The cap creates a liquid tight seal with the filtrate storage bottle.
摘要翻译：从水浴中除去滤液储存瓶的方法包括在滤液储存瓶密封盖的径向突出的唇部的下方插入至少两根手指，并且将至少两个手指提起以从水浴提起瓶子。滤液储存瓶密封盖的侧壁部分的周长小于围绕径向突出的唇缘的圆周。盖子与滤液储存瓶形成液密密封。

4. 发明申请

US20090215150A1 Sample container and filtration apparatus and method of filtration using the same 审中-公开
标题翻译：样品容器和过滤装置及使用其的过滤方法
公开(公告)号：US20090215150A1
公开(公告)日：2009-08-27
申请号：US12070974
申请日：2008-02-22
申请人： Jeffrey Kane , Thomas Taylor , Christopher M. Catinella , Ryan Neil Peter Hall
发明人： Jeffrey Kane , Thomas Taylor , Christopher M. Catinella , Ryan Neil Peter Hall
IPC分类号： C12N1/00 , B01D29/00
CPC分类号： B01L3/50825 , B01L2200/08 , B01L2200/141 , B01L2300/046 , B01L2300/0681 , B01L2300/0832 , G01N1/4077 , G01N2001/4088
摘要： A sample container and filtration apparatus is described comprising a sealable sample container and a surface that is configured to interface with a vacuum base. When the surface interfaces with the vacuum base, a portion of the sample container is broached, providing a pathway for the vacuum source to pull the sample therethrough. In exemplary embodiments, the broachable portion of the sample container comprises an actuating valve. The method for using the sample container and filtration apparatus significantly reduces the possibility of contamination of the sample and during the sample testing procedure relative to the conventional devices and procedures, provides more consistent and reliable test results, and significantly reduces the number of preparation and testing steps for the testing procedure.
摘要翻译：描述了一种样品容器和过滤装置，其包括可密封的样品容器和被配置为与真空底座相接合的表面。当表面与真空基底接触时，样品容器的一部分被拉开，为真空源提供通过其提取样品的通路。在示例性实施例中，样品容器的可拉出部分包括致动阀。使用样品容器和过滤装置的方法显着降低了样品污染的可能性，并且在样品测试过程中相对于传统的设备和程序，提供了更一致和可靠的测试结果，并显着减少了准备和测试的数量测试步骤。

5. 发明申请

US20070153389A1 Optical diffuser having frit based coating with inorganic light diffusing pigments with variable particle size therein 失效
标题翻译：具有玻璃料基涂层的光漫射器，其中具有可变粒径的无机光漫射颜料
公开(公告)号：US20070153389A1
公开(公告)日：2007-07-05
申请号：US11324756
申请日：2006-01-04
申请人： Pramod Sharma , Thomas Taylor
发明人： Pramod Sharma , Thomas Taylor
IPC分类号： G06K7/10 , G02B13/20 , G02B5/02
CPC分类号： G02B5/0278 , C03C8/14 , C03C8/20 , C03C17/007 , C03C17/30 , C03C17/326 , C03C2217/452 , C03C2217/485 , C03C2217/74 , C03C2218/365 , G02B5/0242 , G02B5/0294 , G02F1/133606
摘要： A diffuser is provided that includes a glass substrate with a diffusing coating thereon. The diffusing coating may include one or more layers. In certain example embodiments, the diffusing coating comprises inorganic pigments therein for light diffusing purposes, and the inorganic pigments are sized so as to permit a diffuser having a combination of high visible transmission and good diffusion qualities to be realized. In certain example embodiments, the diffusing coating may be of or include a frit with the inorganic pigments therein.
摘要翻译：提供扩散器，其包括其上具有扩散涂层的玻璃基板。漫射涂层可以包括一层或多层。在某些示例性实施例中，漫射涂层包括其中用于光漫射目的的无机颜料，并且无机颜料的尺寸设定为允许实现具有高可见透射和良好扩散性质的组合的扩散器。在某些示例性实施例中，扩散涂层可以是或包括其中的无机颜料的玻璃料。

6. 发明申请

US20070148601A1 Optical diffuser with UV blocking coating using inorganic materials for blocking UV 失效
标题翻译：具有紫外线阻挡涂层的光学扩散器，使用无机材料阻挡UV
公开(公告)号：US20070148601A1
公开(公告)日：2007-06-28
申请号：US11324758
申请日：2006-01-04
申请人： Pramod Sharma , Desaraju Varaprasad , Thomas Taylor
发明人： Pramod Sharma , Desaraju Varaprasad , Thomas Taylor
IPC分类号： G03C5/00
CPC分类号： F21V9/06 , C03C8/00 , C03C17/007 , C03C17/008 , C03C2217/452 , C03C2217/477 , C03C2218/31 , C03C2218/365 , G02B5/0221 , G02B5/0242 , G02B5/0278 , G02B5/0294 , G02B5/208
摘要： A diffuser is provided in an illumination system, where the diffuser is capable of blocking significant amounts of ultraviolet (UV) radiation. In certain example embodiments of this invention, the diffuser includes a glass substrate which supports a UV coating(s) that blocks significant amounts of UV radiation thereby reducing the amount of UV radiation which can makes its way through the diffuser. In certain example embodiments, the coating may include inorganic particulate in a frit matrix so that the coating may both diffuse visible light and perform UV blocking.
摘要翻译：扩散器设置在照明系统中，其中扩散器能够阻挡大量的紫外（UV）辐射。在本发明的某些示例性实施例中，漫射器包括玻璃基底，其支撑阻挡大量UV辐射的UV涂层，从而减少可以使其穿过扩散器的UV辐射的量。在某些示例性实施方案中，涂层可以包括玻璃料基质中的无机颗粒，使得涂层可以漫射可见光并进行UV阻挡。

7. 发明申请

US20070031655A1 Transparent articles with anti-reflective coating and methods of making the same 失效
标题翻译：具有抗反射涂层的透明制品及其制造方法
公开(公告)号：US20070031655A1
公开(公告)日：2007-02-08
申请号：US11491088
申请日：2006-07-24
申请人： Thomas Taylor
发明人： Thomas Taylor
IPC分类号： B05D3/02 , B32B27/00 , B32B27/06 , B32B17/10
CPC分类号： C03C17/3405 , C03C17/32 , C03C2217/732 , C03C2218/365 , C09D133/16 , G02B1/111 , Y10T428/265 , Y10T428/3154 , Y10T428/31663
摘要： Anti-reflective (AR) coated transparent substrates and methods of making the same are provided wherein the AR coating includes a fluorinated polymer. Preferably, the anti-reflective transparent articles and methods of making the same include a transparent substrate (e.g., glass), and an anti-reflective coating formed of a fluorinated polymer on one (or both) surface(s) of the substrate. If coated on both surfaces of the glass sheet, the fluorinated polymer forming one of the coatings may be the same or different as compared to the fluorinated polymer forming the other coating. In especially preferred embodiments, the fluorinated polymer is the reaction product of at least one fluorinated acrylic ester monomer which is formed over an anchor layer of a hydrolyzed unsaturated alkyl silane adsorbed onto the substrate surface.
摘要翻译：提供抗反射（AR）涂覆的透明基材及其制备方法，其中AR涂层包括含氟聚合物。优选地，抗反射透明制品及其制造方法包括透明基材（例如玻璃）和由基材的一个（或两个）表面上的含氟聚合物形成的抗反射涂层。如果涂覆在玻璃板的两个表面上，则与形成另一涂层的氟化聚合物相比，形成其中一个涂层的氟化聚合物可以相同或不同。在特别优选的实施方案中，氟化聚合物是至少一种氟化丙烯酸酯单体的反应产物，其形成在吸附在基材表面上的水解不饱和烷基硅烷的锚定层上。

8. 发明申请

US20060268099A1 Strategies for scheduling bandwidth-consuming media events 有权
公开(公告)号：US20060268099A1
公开(公告)日：2006-11-30
申请号：US11135994
申请日：2005-05-24
申请人： Peter Potrebic , Thomas Taylor , Naga Pasumarthy
发明人： Peter Potrebic , Thomas Taylor , Naga Pasumarthy
IPC分类号： H04N7/14
CPC分类号： H04N5/782 , H04N21/23439 , H04N21/4147 , H04N21/443 , H04N21/4532 , H04N21/4583 , H04N21/47214 , H04N21/6125 , H04N21/8166
摘要： Scheduling functionality is described for resolving conflicts in the schedules of respective client devices, where the schedules are used to govern the recordation of media programs by the respective client devices. The client devices use virtual tuner functionality to receive media programs over respective communication channels, each channel having a prescribed amount of available bandwidth in which to receive media information. The scheduling functionality includes a conflict identification module for identifying conflicts in the schedules, a solution enumeration module for enumerating solutions to the conflicts, and a conflict resolution module for resolving the conflicts based on the output of the solution enumeration module. In one case, the schedules can be partitioned into a plurality of time segments, and solutions can be enumerated for each time segment in turn.

9. 发明申请

US20060253867A1 Strategies for updating schedules 有权
公开(公告)号：US20060253867A1
公开(公告)日：2006-11-09
申请号：US11122173
申请日：2005-05-04
申请人： Peter Potrebic , Thomas Taylor , Naga Pasumarthy
发明人： Peter Potrebic , Thomas Taylor , Naga Pasumarthy
IPC分类号： H04N5/445 , G06F3/00 , G06F13/00
CPC分类号： H04N5/44543 , H04N5/765 , H04N5/775 , H04N5/781 , H04N5/782 , H04N5/85 , H04N7/17318 , H04N9/8042 , H04N21/26283 , H04N21/26291 , H04N21/4334 , H04N21/47214 , H04N21/6582
摘要： Scheduling functionality is employed at a head-end site to update schedules used by a plurality of respective client devices to define the recording of media presentation events. The scheduling functionality operates by: compiling a master list of unique entries culled from the plurality of schedules; determining whether any entries in the master list require updating; and updating, based on the determining, at least one of the plurality of schedules. The scheduling functionality helps reduce the amount of redundant processing operations involved in updating the plurality of schedules, and therefore provides an efficient technique for updating the schedules.

10. 发明申请

US20060071498A1 Trackless cargo bed organizer 失效
标题翻译：无轨货床组织者
公开(公告)号：US20060071498A1
公开(公告)日：2006-04-06
申请号：US11152624
申请日：2005-06-14
申请人： Thomas Taylor
发明人： Thomas Taylor
IPC分类号： B60R9/00 , B60R7/00
CPC分类号： B60N2/345 , B60P3/14
摘要： A cargo bed organizer 10 which obviates the need for a track to be “mounted” and/or installed and/or otherwise formed in the cargo bed 350 of a selectively movable assembly 500, and which is selectively and removably received into the cargo bed 350 of a selectively movable assembly 500, and which has at least one stopping member portion 48.
摘要翻译：一种货床组织器10，其不需要将轨道“安装”和/或安装和/或以其他方式形成在可选择性移动的组件500的货物床350中，并且其被选择性地和可移除地容纳在货物床350中具有至少一个止动件部分48的选择性可移动组件500。

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