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1. 发明授权

US5749376A Medical treatment and waste disposal method 失效
标题翻译：医疗和废物处理方法
公开(公告)号：US5749376A
公开(公告)日：1998-05-12
申请号：US561399
申请日：1995-11-21
申请人： Peter J. Wilk , Charles L. Knoll , Eugene Wexler
发明人： Peter J. Wilk , Charles L. Knoll , Eugene Wexler
IPC分类号： A61B17/06 , A61B19/02 , A61B19/00
CPC分类号： A61B50/362 , A61B17/06161 , A61B2050/364 , Y10S128/917 , Y10S128/919 , Y10S422/901
摘要： A medical method utilizes a medical instrument such as a suturing needle made of biocompatible material. In addition, a medical operating room is provided with a container of a solvent fluidic material. During a medical procedure, the instrument is used to operate on a patient in the operating room. Upon completed use of the instrument, it is deposited in the container in the operating room, whereupon the instrument dissolves in the container.
摘要翻译：医疗方法利用医疗器械，例如由生物相容性材料制成的缝合针。此外，医疗手术室设置有溶剂流体材料的容器。在医疗过程中，仪器用于在手术室中对患者进行操作。仪器完成使用后，将其存放在手术室的容器中，仪器溶解于容器内。

2. 发明授权

US5242398A Catheter assembly and related method 失效
标题翻译：导管组件及相关方法
公开(公告)号：US5242398A
公开(公告)日：1993-09-07
申请号：US850433
申请日：1992-03-12
申请人： Charles L. Knoll , Eugene Wexler , Peter J. Wilk
发明人： Charles L. Knoll , Eugene Wexler , Peter J. Wilk
IPC分类号： A61F2/958 , A61M25/01
CPC分类号： A61M25/10 , A61M25/0111 , A61M2025/0062
摘要： A catheter assembly comprises a catheter and a sheath enclosing the catheter to preserve the sterility thereof, the sheath being provided with a plurality of fold lines which form accordion-like pleats to enable a collapse of the sheath at a point of insertion of the catheter into a patient. The sheath is provided at a distal end of the catheter with a flange for engaging a patient during an insertion of the catheter into the patient. A catheter assembly also comprises an anchor balloon attached to the catheter at a distal end thereof, an ancillary balloon attached to the catheter at a point spaced in a proximal direction from the anchor balloon, a tube connecting the ancillary balloon to the anchor balloon so as to enable communication therebetween, and a flow stop mounted to the catheter for preventing fluid from returning to the tube from the anchor balloon upon a pressurization of the anchor balloon with fluid forced from the tube by an application of pressure to the ancillary balloon. A hollow catheter plug defining a flash chamber and having a transparent wall is connected to the catheter at a proximal end thereof for communicating with the catheter. A valve is connected to the plug for preventing fluid flow from the flash chamber.
摘要翻译：导管组件包括导管和包围导管以保护其无菌性的护套，护套设置有多个折叠线，其形成折叠式褶皱，以使导管插入点处的护套脱落病人。护套在导管的远端处设置有用于在将导管插入患者体内与患者接合的凸缘。导管组件还包括在其远端处附接到导管的锚固气囊，在与锚定气囊近端方向间隔开的点处附接到导管的辅助气囊，将辅助气囊连接到锚定球囊的管，以便以使得它们之间能够进行通信，以及安装在导管上的流动阻挡件，用于防止流体在锚固气囊被加压时从锚固气球返回到管中，而流体通过施加压力而被迫从管中流出到辅助气囊。限定闪蒸室并具有透明壁的中空导管插头在其近端连接到导管，用于与导管连通。阀连接到塞子上以防止流体从闪蒸室流出。

3. 发明授权

US08685058B2 Surgical closure method and associated device 有权
标题翻译：手术闭合方法及相关装置
公开(公告)号：US08685058B2
公开(公告)日：2014-04-01
申请号：US11369477
申请日：2006-03-07
申请人： Peter J. Wilk
发明人： Peter J. Wilk
IPC分类号： A61D1/00
CPC分类号： A61B17/00234 , A61B17/0469 , A61B17/068 , A61B17/128 , A61B2017/00349 , A61B2017/0496 , A61B2017/081
摘要： In a surgical method, an incision is formed in a layer of organic tissue defining a wall having an inner side and an outer side. The incision has a pair of opposing lips or edges. The lips or edges are retracted towards the inner side of the tissue wall and approximated to one another. Thereafter, one or more closure elements are applied to the inwardly pulled lips or edges.
摘要翻译：在外科方法中，在限定具有内侧和外侧的壁的有机组织层中形成切口。切口有一对相对的嘴唇或边缘。嘴唇或边缘朝向组织壁的内侧缩回并彼此近似。此后，将一个或多个闭合元件施加到向内拉的嘴唇或边缘。

4. 发明授权

US07753934B2 Medical closure method and associated device 有权
标题翻译：医疗闭合方法及相关装置
公开(公告)号：US07753934B2
公开(公告)日：2010-07-13
申请号：US11387528
申请日：2006-03-23
申请人： Peter J. Wilk
发明人： Peter J. Wilk
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/085 , A61B2017/00637 , A61B2017/00659
摘要： A surgical closure method utilizes a surgical device including an elongate tube, a flexible web member disposed in a collapsed configuration inside the tube, and a push rod disposed at least partially inside the tube for pushing the web member from the tube. A distal end portion of the tube is inserted through an opening or wound in a wall of a hollow body organ. The rod is pushed in a distal direction along the tube to eject the web member from the distal end of the tube. The ejected web member is expanded from the collapsed configuration to an expanded configuration. The expanded web member is placed in contact with the wall of the organ over the opening or wound. Subsequently the expanded web member is attached to the wall of the organ.
摘要翻译：手术闭合方法利用外科装置，其包括细长管，设置在管内的收缩构造的柔性腹板构件，以及至少部分地设置在管内部的推杆，用于将腹板构件从管中推动。管的远端部分穿过开口插入或缠绕在中空体器官的壁中。杆沿着管的远端方向推动，以从管的远端排出腹板构件。排出的网构件从折叠构型扩展到扩展构型。膨胀的腹板构件放置在开口或伤口上与器官的壁接触。随后，膨胀的腹板构件附着到器官的壁上。

5. 发明授权

US07011095B2 Valve designs for left ventricular conduits 失效
公开(公告)号：US07011095B2
公开(公告)日：2006-03-14
申请号：US10463798
申请日：2003-06-18
申请人： Scott J. Wolf , Peter J. Wilk , Nancy M. Briefs
发明人： Scott J. Wolf , Peter J. Wilk , Nancy M. Briefs
IPC分类号： A61F2/06 , A61B17/08
CPC分类号： A61F2/94 , A61F2/06 , A61F2/2493 , A61F2/848 , A61F2/958 , A61F2002/821 , A61F2230/0067 , A61F2230/0078 , A61F2230/008 , A61M39/24
摘要： Disclosed is a conduit that provides a bypass around a stenosis or occlusion in a coronary artery. The conduit is adapted to be positioned in the myocardium to provide a passage for blood to flow from a heart chamber to a coronary artery, at a site distal to the blockage or stenosis in the coronary artery. The conduit has a one-way valve positioned therein to prevent the backflow of blood from the coronary artery into the heart chamber.

6. 发明授权

US06730014B2 Medical treatment method and device utilizing magnetic particles 失效
标题翻译：使用磁性颗粒的医疗方法和装置
公开(公告)号：US06730014B2
公开(公告)日：2004-05-04
申请号：US09755485
申请日：2001-01-05
申请人： Peter J. Wilk
发明人： Peter J. Wilk
IPC分类号： A61N200
CPC分类号： A61N2/06
摘要： In a medical treatment method, magnetic elements are injected into organic tissues of a patient. The magnetic elements are disposed, upon injection, on opposite sides of tissues or a hole to be closed or collapsed. Owing to magnetic attraction between the magnetic elements, the organic tissues of the patient are drawn together to constrict tissues or to close or collapse a wound or vessel.
摘要翻译：在医疗方法中，将磁性元件注入患者的有机组织。磁性元件在注射时设置在组织的相对侧或要封闭或折叠的孔中。由于磁性元件之间的磁吸引力，患者的有机组织被牵拉在一起以收缩组织或闭合或折叠伤口或容器。

7. 发明授权

US06694983B2 Delivery methods for left ventricular conduit 失效
公开(公告)号：US06694983B2
公开(公告)日：2004-02-24
申请号：US10092916
申请日：2002-03-08
申请人： Scott J. Wolf , Peter J. Wilk , Vincent Pompili
发明人： Scott J. Wolf , Peter J. Wilk , Vincent Pompili
IPC分类号： A61B1900
CPC分类号： A61M25/0147 , A61B2017/00247 , A61B2017/00252 , A61B2017/22071 , A61B2017/22095 , A61B2018/00392 , A61F2/2493 , A61F2/86 , A61F2/95 , A61F2/958 , A61M25/0152 , A61M25/0155 , A61M25/0194 , A61M25/10 , A61M25/1006 , A61M25/1011 , A61M2025/0096 , A61M2025/0197 , A61M2025/1095 , A61M2025/1097 , A61M2210/125
摘要： Described herein are various methods and apparatuses for delivering stents or conduits and other devices into the myocardium of a patient. One preferred stent delivery system provides access to the insertion site in the myocardium by advancing a delivery catheter through a blockage in a coronary artery, or around the blockage through a coronary vein or through a channel or tunnel formed around the blockage. In one embodiment, once the distal end of the delivery catheter is adjacent the myocardium, an angled bend is created in the catheter by actuating expandable steering guides mounted to the catheter which cooperate with the walls of the blood vessel to cause the catheter to turn. Then, a guidewire is advanced through the delivery catheter and into the myocardium. In another embodiment, a tip-deflecting pull wire extends from the distal end of the delivery catheter which may be actuated to turn towards and then inserted into the myocardium. In another embodiment, an exit port facing the insertion site is provided within the catheter or a balloon mounted on the catheter so that a guidewire may be directed through a lumen and out the exit port into the myocardium. Once the guidewire punctures into the myocardium, the guidewire is anchored using barbs, balloons or other actuatable members to secure the guidewire to the myocardium. Subsequently, using a push-pull mechanism, stents and other medical devices can be advanced over the guidewire into the myocardium.

8. 发明授权

US06641610B2 Valve designs for left ventricular conduits 失效
标题翻译：阀门设计用于左心室导管
公开(公告)号：US06641610B2
公开(公告)日：2003-11-04
申请号：US09368393
申请日：1999-08-04
申请人： Scott J. Wolf , Greg R. Furnish , Todd A. Hall , David Y. Phelps , Peter J. Wilk , Nancy C. Briefs , William Santamore , Daniel Burkhoff
发明人： Scott J. Wolf , Greg R. Furnish , Todd A. Hall , David Y. Phelps , Peter J. Wilk , Nancy C. Briefs , William Santamore , Daniel Burkhoff
IPC分类号： A61F206
CPC分类号： A61F2/94 , A61F2/06 , A61F2/2493 , A61F2/848 , A61F2/958 , A61F2002/821 , A61F2230/0067 , A61F2230/0078 , A61F2230/008 , A61M39/24
摘要： Disclosed is a conduit that provides a bypass around a stenosis or occlusion in a coronary artery. The conduit is adapted to be positioned in the myocardium to provide a passage for blood to flow from a heart chamber to a coronary artery, at a site distal to the blockage or stenosis in the coronary artery. The conduit has a one-way valve positioned therein to prevent the backflow of blood from the coronary artery into the heart chamber.
摘要翻译：公开了一种导管，其围绕冠状动脉狭窄或闭塞提供旁路。导管适于定位在心肌中以提供血液从冠状动脉血管流过冠状动脉的阻塞或狭窄位置的通道。导管具有定位在其中的单向阀，以防止血液从冠状动脉回流进心室。

9. 发明授权

US06387119B2 Delivery methods for left ventricular conduit 失效
标题翻译：输送方法为左心室导管
公开(公告)号：US06387119B2
公开(公告)日：2002-05-14
申请号：US09796590
申请日：2001-03-02
申请人： Scott J. Wolf , Peter J. Wilk , Vincent Pompili
发明人： Scott J. Wolf , Peter J. Wilk , Vincent Pompili
IPC分类号： A61F206
CPC分类号： A61M25/0147 , A61B2017/00247 , A61B2017/00252 , A61B2017/22071 , A61B2017/22095 , A61B2018/00392 , A61F2/2493 , A61F2/86 , A61F2/95 , A61F2/958 , A61M25/0152 , A61M25/0155 , A61M25/0194 , A61M25/10 , A61M25/1006 , A61M25/1011 , A61M2025/0096 , A61M2025/0197 , A61M2025/1095 , A61M2025/1097 , A61M2210/125
摘要： Described herein are various methods and apparatuses for delivering stents or conduits and other devices into the myocardium of a patient. One preferred stent delivery system provides access to the insertion site in the myocardium by advancing a delivery catheter through a blockage in a coronary artery, or around the blockage through a coronary vein or through a channel or tunnel formed around the blockage. In one embodiment, once the distal end of the delivery catheter is adjacent the myocardium, an angled bend is created in the catheter by actuating expandable steering guides mounted to the catheter which cooperate with the walls of the blood vessel to cause the catheter to turn. Then, a guidewire is advanced through the delivery catheter and into the myocardium. In another embodiment, a tip-deflecting pull wire extends from the distal end of the delivery catheter which may be actuated to turn towards and then inserted into the myocardium. In another embodiment, an exit port facing the insertion site is provided within the catheter or a balloon mounted on the catheter so that a guidewire may be directed through a lumen and out the exit port into the:.myocardium. Once the guidewire punctures into the myocardium, the guidewire is anchored using barbs, balloons or other actuatable members to secure the guidewire to the myocardium. Subsequently, using a push-pull mechanism, stents and other medical devices can be advanced over the guidewire into the myocardium.
摘要翻译：本文描述了用于将支架或管道和其他装置输送到患者的心肌中的各种方法和装置。一个优选的支架递送系统通过使输送导管通过冠状动脉阻塞或通过冠状静脉或通过在阻塞周围形成的通道或隧道周围的阻塞来推进进入心肌中的插入部位。在一个实施例中，一旦输送导管的远端与心肌相邻，则通过致动安装到导管的可扩展转向引导件，在导管中产生成角度的弯曲部，其与血管的壁配合以使导管转动。然后，导丝通过输送导管进入心肌。在另一个实施例中，尖端偏转拉线从输送导管的远端延伸，可以被致动以转向然后插入心肌。在另一个实施例中，面向插入部位的出口端口设置在导管内或安装在导管上的球囊上，使得导丝线可以被引导通过内腔并且离开出口进入心肌。一旦导丝穿刺入心肌，就使用倒刺，气球或其他可致动部件来固定导丝，以将导丝固定到心肌。随后，使用推拉机构，支架和其他医疗装置可以在导丝上前进进入心肌。

10. 发明授权

US06302892B1 Blood flow conduit delivery system and method of use 失效
标题翻译：血流导管输送系统及使用方法
公开(公告)号：US06302892B1
公开(公告)日：2001-10-16
申请号：US09368644
申请日：1999-08-04
申请人： Peter J. Wilk
发明人： Peter J. Wilk
IPC分类号： A61F1100
CPC分类号： A61F2/2493 , A61B2017/00252 , A61F2/064
摘要： Described herein is a catheter system for delivering an L-shaped conduit into the body of a patient between the left ventricle and coronary artery. A shunt preferably made of semirigid material is inserted into the lumen of a delivery catheter. The delivery catheter is advanced within the patient until its distal end is located adjacent to the desired insertion site, which is preferably the junction between a coronary artery and passageway formed in the myocardium between the left ventricle and coronary artery. A proximal section of the shunt is first advanced out of the delivery catheter into the myocardial passageway. A distal section of the shunt is advanced into the coronary artery, preferably by advancing the distal section of the shunt into the myocardial passageway and then pulling the distal section back into the coronary artery, or by pushing the distal section of the shunt in a folded configuration out of the delivery catheter into the coronary artery. In one embodiment, the shunt is made of a collapsible material for insertion into the delivery catheter, the shunt expanding upon removal from the delivery catheter.
摘要翻译：这里描述的是用于将L形导管输送到左心室和冠状动脉之间的患者体内的导管系统。优选由半刚性材料制成的分流器插入输送导管的内腔中。输送导管在患者体内前进，直到其远端位于所需插入位置附近，该位置优选为冠状动脉与左心室和冠状动脉之间的心肌中形成的通路之间的连接点。分流器的近端部分首先从输送导管进入心肌通道。分流器的远端部分推进到冠状动脉中，优选地通过使分流器的远端部分进入心肌通道，然后将远端部分拉回冠状动脉，或者通过将分流器的远端部分推向折叠配置输出导管进入冠状动脉。在一个实施例中，分流器由用于插入输送导管的可折叠材料制成，在从输送导管移除时分流器膨胀。

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