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1. 发明授权

US07030411B2 Electronic unit integrated into a flexible polymer body 有权
标题翻译：电子单元集成到柔性聚合物体内
公开(公告)号：US07030411B2
公开(公告)日：2006-04-18
申请号：US10939771
申请日：2004-09-13
申请人： Peter A. Krulevitch , Mariam N. Maghribi , William J. Benett , Julie K. Hamilton , Klint A. Rose , James Courtney Davidson , Mark S. Strauch
发明人： Peter A. Krulevitch , Mariam N. Maghribi , William J. Benett , Julie K. Hamilton , Klint A. Rose , James Courtney Davidson , Mark S. Strauch
IPC分类号： H01L29/04 , H01L31/20 , H01L31/036 , H01L31/0376
CPC分类号： A61N1/0456 , A61B2560/0412 , A61N1/0452 , A61N1/0476 , A61N1/0492 , A61N1/05 , A61N1/0534 , H01L23/5387 , H01L25/065 , H01L2924/0002 , H01L2924/09701 , H05K1/0313 , H05K1/0393 , H05K2201/0162 , H05K2201/09118 , H01L2924/00
摘要： A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.
摘要翻译：剥离和粘贴电子系统包括硅树脂体和至少一个可操作地连接到硅氧烷体的电子单元。该电子系统是通过在衬底上提供硅树脂层，在硅树脂层上提供金属层，并提供至少一个与金属层连接的电子单元来制造的。

2. 发明授权

US07342311B2 Electronic unit integrated into a flexible polymer body 有权
标题翻译：电子单元集成到柔性聚合物体内
公开(公告)号：US07342311B2
公开(公告)日：2008-03-11
申请号：US11326967
申请日：2006-01-05
申请人： Peter A. Krulevitch , Mariam N. Maghribi , William J. Benett , Julie K. Hamilton , Klint A. Rose , James Courtney Davidson , Mark S. Strauch
发明人： Peter A. Krulevitch , Mariam N. Maghribi , William J. Benett , Julie K. Hamilton , Klint A. Rose , James Courtney Davidson , Mark S. Strauch
IPC分类号： H01L23/04 , H01L23/34
CPC分类号： H01L25/165 , B81C1/0023 , H01L21/6835 , H01L31/048 , H01L31/0543 , H01L2221/68345 , H01L2924/0002 , H01L2924/09701 , H01L2924/19041 , H01L2924/19105 , Y02E10/52 , H01L2924/00
摘要： A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.
摘要翻译：剥离和粘贴电子系统包括硅树脂体和至少一个可操作地连接到硅氧烷体的电子单元。该电子系统是通过在衬底上提供硅树脂层，在硅树脂层上提供金属层，并提供至少一个与金属层连接的电子单元来制造的。

3. 发明授权

US06991963B2 Electronic unit integrated into a flexible polymer body 有权
公开(公告)号：US06991963B2
公开(公告)日：2006-01-31
申请号：US10835226
申请日：2004-04-28
申请人： Peter A. Krulevitch , Mariam N. Maghribi , William J. Benett , Julie K. Hamilton , Klint A. Rose , James Courtney Davidson , Mark S. Strauch
发明人： Peter A. Krulevitch , Mariam N. Maghribi , William J. Benett , Julie K. Hamilton , Klint A. Rose , James Courtney Davidson , Mark S. Strauch
IPC分类号： H01L21/44
CPC分类号： A61N1/0456 , A61B2560/0412 , A61N1/0452 , A61N1/0476 , A61N1/0492 , A61N1/05 , A61N1/0534 , H01L23/5387 , H01L25/065 , H01L2924/0002 , H01L2924/09701 , H05K1/0313 , H05K1/0393 , H05K2201/0162 , H05K2201/09118 , H01L2924/00
摘要： A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.

4. 发明授权

US06878643B2 Electronic unit integrated into a flexible polymer body 有权
公开(公告)号：US06878643B2
公开(公告)日：2005-04-12
申请号：US10323219
申请日：2002-12-18
申请人： Peter A. Krulevitch , Mariam N. Maghribi , William J. Benett , Julie K. Hamilton , Klint A. Rose , James Courtney Davidson , Mark S. Strauch
发明人： Peter A. Krulevitch , Mariam N. Maghribi , William J. Benett , Julie K. Hamilton , Klint A. Rose , James Courtney Davidson , Mark S. Strauch
IPC分类号： A61N1/04 , A61N1/05 , H01L23/538 , H01L25/065 , H05K1/00 , H05K1/03 , H01L21/31
CPC分类号： A61N1/0456 , A61B2560/0412 , A61N1/0452 , A61N1/0476 , A61N1/0492 , A61N1/05 , A61N1/0534 , H01L23/5387 , H01L25/065 , H01L2924/0002 , H01L2924/09701 , H05K1/0313 , H05K1/0393 , H05K2201/0162 , H05K2201/09118 , H01L2924/00
摘要： A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.

5. 发明授权

US07025323B2 Low power integrated pumping and valving arrays for microfluidic systems 有权
公开(公告)号：US07025323B2
公开(公告)日：2006-04-11
申请号：US09957894
申请日：2001-09-21
申请人： Peter A. Krulevitch , William J. Benett , Klint A. Rose , Julie Hamilton , Mariam Maghribi
发明人： Peter A. Krulevitch , William J. Benett , Klint A. Rose , Julie Hamilton , Mariam Maghribi
IPC分类号： F16K31/124
CPC分类号： F16K99/0001 , F15C5/00 , F16K99/0011 , F16K99/0015 , F16K99/0044 , F16K99/0048 , F16K99/0059 , F16K99/0061 , F16K2099/0074 , F16K2099/0078 , F16K2099/0084
摘要： Low power integrated pumping and valving arrays which provide a revolutionary approach for performing pumping and valving approach for performing pumping and valving operations in microfabricated fluidic systems for applications such as medical diagnostic microchips. Traditional methods rely on external, large pressure sources that defeat the advantages of miniaturization. Previously demonstrated microfabrication devices are power and voltage intensive, only function at sufficient pressure to be broadly applicable. This approach integrates a lower power, high-pressure source with a polymer, ceramic, or metal plug enclosed within a microchannel, analogous to a microsyringe. When the pressure source is activated, the polymer plug slides within the microchannel, pumping the fluid on the opposite side of the plug without allowing fluid to leak around the plug. The plugs also can serve as microvalves.

6. 发明授权

US09290855B2 Stabilization of green bodies via sacrificial gelling agent during electrophoretic deposition 有权
标题翻译：在电泳沉积期间通过牺牲胶凝剂稳定生物体
公开(公告)号：US09290855B2
公开(公告)日：2016-03-22
申请号：US13453933
申请日：2012-04-23
申请人： Marcus A. Worsley , Joshua D. Kuntz , Klint A. Rose
发明人： Marcus A. Worsley , Joshua D. Kuntz , Klint A. Rose
IPC分类号： B32B7/02 , D02G3/00 , C04B35/51 , C25D13/02 , C25D5/10 , H01S3/16 , H01S3/06
CPC分类号： C25D13/02 , C25D5/10 , H01S3/0612 , H01S3/1685 , Y10T428/12021 , Y10T428/12458 , Y10T428/24926
摘要： In one embodiment, a method for electrophoretic deposition of a three-dimensionally patterned green body includes suspending a first material in a gelling agent above a patterned electrode of an electrophoretic deposition (EPD) chamber, and gelling the suspension while applying a first electric field to the suspension to cause desired patterning of the first material in a resulting gelation. In another embodiment, a ceramic, metal, or cermet includes a plurality of layers, wherein each layer includes a gradient in composition, microstructure, and/or density in an x-y plane oriented parallel to a plane of deposition of the plurality of layers along a predetermined distance in a z-direction perpendicular to the plane of deposition.
摘要翻译：在一个实施例中，三维图案化的生坯的电泳沉积方法包括将第一材料悬浮在电泳沉积（EPD）室的图案化电极之上的胶凝剂中，并在施加第一电场的同时胶凝悬浮液所述悬浮液在所得凝胶化中引起所述第一材料的所需图案化。在另一个实施方案中，陶瓷，金属或金属陶瓷包括多个层，其中每个层包括在平行于沿着多个层的沉积平面定向的xy平面中的组成，微观结构和/或密度的梯度在垂直于沉积平面的z方向上的预定距离。

7. 发明授权

US09144799B2 Modular microfluidic system for biological sample preparation 有权
标题翻译：用于生物样品制备的模块化微流体系统
公开(公告)号：US09144799B2
公开(公告)日：2015-09-29
申请号：US12943677
申请日：2010-11-10
申请人： Klint A. Rose , Raymond P. Mariella, Jr. , Christopher G. Bailey , Kevin Dean Ness
发明人： Klint A. Rose , Raymond P. Mariella, Jr. , Christopher G. Bailey , Kevin Dean Ness
IPC分类号： C12M1/33 , C12M3/08 , B01L3/00 , B03C5/02 , G01N35/00
CPC分类号： B01L3/502761 , B01L3/502753 , B01L2200/027 , B01L2200/04 , B01L2300/0681 , B01L2400/0436 , B01L2400/0439 , B03C5/026 , B03C2201/26 , G01N2035/00326
摘要： A reconfigurable modular microfluidic system for preparation of a biological sample including a series of reconfigurable modules for automated sample preparation adapted to selectively include a) a microfluidic acoustic focusing filter module, b) a dielectrophoresis bacteria filter module, c) a dielectrophoresis virus filter module, d) an isotachophoresis nucleic acid filter module, e) a lyses module, and f) an isotachophoresis-based nucleic acid filter.
摘要翻译：一种用于制备生物样品的可重构模块化微流体系统，包括用于自动化样品制备的一系列可重新配置模块，其适于选择性地包括a）微流体声学聚焦滤光器模块，b）介电电泳细菌滤膜模块，c）介电泳病毒过滤器模块， d）等速电泳核酸过滤器模块，e）裂解模块和f）基于等电泳的核酸过滤器。

8. 发明授权

US09285340B2 Methods for separating particles and/or nucleic acids using isotachophoresis 有权
标题翻译：使用等速电泳法分离颗粒和/或核酸的方法
公开(公告)号：US09285340B2
公开(公告)日：2016-03-15
申请号：US12542215
申请日：2009-08-17
申请人： Byoungsok Jung , Kevin Ness , Klint A. Rose
发明人： Byoungsok Jung , Kevin Ness , Klint A. Rose
IPC分类号： G01N27/447
CPC分类号： G01N27/44747 , G01N27/44773 , G01N2030/8827
摘要： According to one embodiment, a method includes co-feeding fluids comprising a leading electrolyte, a trailing electrolyte, and at least one of DNA and RNA to a channel, and applying an electric field to the fluids in a direction perpendicular to an axis of the channel for inducing transverse isotachophoresis. In another embodiment, a method includes co-feeding fluids to a channel. The fluids include a leading electrolyte, a trailing electrolyte, biological objects, at least one of DNA and RNA, and a spacer electrolyte having an electrophoretic mobility that is between an electrophoretic mobility of at least some of the biological objects and an electrophoretic mobility of the at least one of the DNA and the RNA. The method also includes applying an electric field to the fluids in a direction perpendicular to an axis of the channel for inducing transverse isotachophoresis. Other methods of isotachophoresis are disclosed in addition to these.
摘要翻译：根据一个实施方案，一种方法包括将包含前导电解质，尾电解质和至少一种DNA和RNA的流体的流体共同输送到通道，以及在垂直于诱导横向等电泳的通道。在另一个实施例中，一种方法包括将流体共同供给到通道。流体包括前导电解质，尾电解质，生物物体，DNA和RNA中的至少一种以及具有电泳迁移率的间隔电解质，所述间隔电解质位于至少一些生物体的电泳迁移率和电泳迁移率之间至少一个DNA和RNA。该方法还包括在垂直于通道的轴线的方向上向流体施加电场以诱导横向等速电泳。除此之外还公开了其他的等速电泳法。

9. 发明授权

US08727129B2 Microfluidic ultrasonic particle separators with engineered node locations and geometries 有权
标题翻译：具有工程节点位置和几何形状的微流体超声波颗粒分离器
公开(公告)号：US08727129B2
公开(公告)日：2014-05-20
申请号：US13571640
申请日：2012-08-10
申请人： Klint A. Rose , Karl A. Fisher , Douglas A. Wajda , Raymond P. Mariella, Jr. , Christopher Bailey , Dietrich Dehlinger , Maxim Shusteff , Byoungsok Jung , Kevin D. Ness
发明人： Klint A. Rose , Karl A. Fisher , Douglas A. Wajda , Raymond P. Mariella, Jr. , Christopher Bailey , Dietrich Dehlinger , Maxim Shusteff , Byoungsok Jung , Kevin D. Ness
IPC分类号： B03B5/00
CPC分类号： B01L3/50273 , B01D21/28 , B01D21/283 , B01D2221/10 , B01L3/502761 , B01L2200/0631 , B01L2200/0636 , B01L2200/0652 , B01L2300/0816 , B01L2300/0864 , B01L2400/0439 , B01L2400/0487 , G01N1/4077 , G01N33/48728 , G01N33/491 , G01N2001/4094
摘要： An ultrasonic microfluidic system includes a separation channel for conveying a sample fluid containing small particles and large particles, flowing substantially parallel, adjacent to a recovery fluid, with which it is in contact. An acoustic transducer produces an ultrasound standing wave, that generates a pressure field having at least one node of minimum pressure amplitude. An acoustic extension structure is located proximate to said separation channel for positioning said acoustic node off center in said acoustic area and concentrating the large particles in said recovery fluid stream.
摘要翻译：超声波微流体系统包括用于输送包含小颗粒和大颗粒的样品流体的分离通道，所述样品流体基本上平行于与其接触的回收流体相邻流动。声换能器产生超声驻波，其产生具有至少一个最小压力振幅节点的压力场。声学延伸结构位于所述分离通道附近，用于将所述声音节点偏离所述声学区域的中心，并将大颗粒集中在所述回收流体流中。

10. 发明申请

US20120052511A1 METHODS FOR CONTROLLING PORE MORPHOLOGY IN AEROGELS USING ELECTRIC FIELDS AND PRODUCTS THEREOF 有权
标题翻译：使用电场及其产品控制空间形态的方法
公开(公告)号：US20120052511A1
公开(公告)日：2012-03-01
申请号：US13180440
申请日：2011-07-11
申请人： Marcus A. Worsley , Theodore F. Baumann , Joe H. Satcher, JR. , Tammy Y. Olson , Joshua D. Kuntz , Klint A. Rose
发明人： Marcus A. Worsley , Theodore F. Baumann , Joe H. Satcher, JR. , Tammy Y. Olson , Joshua D. Kuntz , Klint A. Rose
IPC分类号： B32B3/26 , C12N5/00 , B32B5/22 , H01B1/08 , H01B1/04 , G01N33/53 , H01B1/00
CPC分类号： H01B1/08 , B01J13/0091 , Y10T428/249953 , Y10T428/249986
摘要： In one embodiment, an aerogel or xerogel includes column structures of a material having minor pores therein and major pores devoid of the material positioned between the column structures, where longitudinal axes of the major pores are substantially parallel to one another. In another embodiment, a method includes heating a sol including aerogel or xerogel precursor materials to cause gelation thereof to form an aerogel or xerogel and exposing the heated sol to an electric field, wherein the electric field causes orientation of a microstructure of the sol during gelation, which is retained by the aerogel or xerogel. In one approach, an aerogel has elongated pores extending between a material arranged in column structures having structural characteristics of being formed from a sol exposed to an electric field that causes orientation of a microstructure of the sol during gelation which is retained by the elongated pores of the aerogel.
摘要翻译：在一个实施方案中，气凝胶或干凝胶包括其中具有小孔的材料的柱结构，以及没有位于柱结构之间的材料的主要孔，其中主孔的纵轴基本上彼此平行。在另一个实施方案中，一种方法包括加热包括气凝胶或干凝胶前体材料的溶胶，使其凝胶形成气凝胶或干凝胶，并将加热的溶胶暴露于电场，其中电场引起凝胶化过程中溶胶微结构的取向，由气凝胶或干凝胶保留。在一种方法中，气凝胶具有延伸的细孔，所述孔在布置在柱结构中的材料之间延伸，所述材料具有由暴露于电场的溶胶形成的结构特征，所述溶胶引起凝胶化期间溶胶的微结构的取向，气凝胶

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