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1. 发明授权

US08339463B2 Camera lens calibration system 有权
标题翻译：相机镜头校准系统
公开(公告)号：US08339463B2
公开(公告)日：2012-12-25
申请号：US13181491
申请日：2011-07-12
申请人： Peng-Kun Wang , Bin Zhang , Ming Shen
发明人： Peng-Kun Wang , Bin Zhang , Ming Shen
IPC分类号： H04N17/00
CPC分类号： G03B43/00 , G03B2205/0092
摘要： The invention is discloses a camera lens calibration system and method thereof, which comprise a calibration platform, the calibration platform comprise a calibration structure. A calibration camera lens to be calibrated is placed on the calibration platform. An image testing module is provided for capturing a target pattern from a target pattern display through the calibration camera lens to be calibrated for getting an image pattern. The image testing module provides a contrast parameter computation for calculating the contrast parameter of image pattern and showing results on a display.
摘要翻译：本发明公开了一种包括校准平台的相机镜头校准系统及其方法，所述校准平台包括校准结构。要校准的校准相机镜头放置在校准平台上。提供图像测试模块，用于通过要校准的校准相机镜头从目标图案显示中捕获目标图案以获得图像图案。图像测试模块提供用于计算图像图案的对比度参数并在显示器上显示结果的对比度参数计算。

2. 发明申请

US20120169885A1 Camera Lens Calibration System 有权
标题翻译：相机镜头校准系统
公开(公告)号：US20120169885A1
公开(公告)日：2012-07-05
申请号：US13181491
申请日：2011-07-12
申请人： Peng-Kun Wang , Bin Zhang , Ming Shen
发明人： Peng-Kun Wang , Bin Zhang , Ming Shen
IPC分类号： H04N17/00
CPC分类号： G03B43/00 , G03B2205/0092
摘要： The invention is discloses a camera lens calibration system and method thereof, which comprise a calibration platform, the calibration platform comprise a calibration structure. A calibration camera lens to be calibrated is placed on the calibration platform. An image testing module is provided for capturing a target pattern from a target pattern display through the calibration camera lens to be calibrated for getting an image pattern. The image testing module provides a contrast parameter computation for calculating the contrast parameter of image pattern and showing results on a display.
摘要翻译：本发明公开了一种包括校准平台的相机镜头校准系统及其方法，所述校准平台包括校准结构。要校准的校准相机镜头放置在校准平台上。提供图像测试模块，用于通过要校准的校准相机镜头从目标图案显示中捕获目标图案以获得图像图案。图像测试模块提供用于计算图像图案的对比度参数并在显示器上显示结果的对比度参数计算。

3. 发明授权

US6107021A Synthetic peptide vaccines for foot-and-mouth disease 失效
标题翻译：合成肽疫苗用于口蹄疫
公开(公告)号：US6107021A
公开(公告)日：2000-08-22
申请号：US100600
申请日：1998-06-20
申请人： Chang Yi Wang , Ming Shen
发明人： Chang Yi Wang , Ming Shen
IPC分类号： G01N33/53 , A61K39/00 , A61K39/125 , A61P31/12 , C07K14/09 , G01N37/00 , C12Q1/70 , A61K38/00
CPC分类号： C07K14/005 , C12N15/52 , A61K39/00 , C12N2770/32122 , C12N2770/32134
摘要： The present invention relates to the use of a peptide composition as an immunogen, with each peptide contained therein comprising a target antigenic site derived from the VP1 capsid protein of Foot-and-Mouth Disease Virus (FMDV). The antigenic site is covalently linked to a helper T cell epitope and, preferably, to other immunostimulatory sequences, preferably by conventional peptide bond(s) through direct synthesis, for the prevention of FMDV infection and eradication of Foot-and-Mouth Disease (FMD). More particularly, the present invention relates to the use of such peptide composition as an immunogen to elicit the production in animals including swine, cattle, sheep, goats and susceptible wild species, of high titer polyclonal antibodies that can effectively neutralize, in vitro, multiple strains or serotypes of FMDV, and to the use of such composition as a vaccine to prevent, and/or reduce the incidence of, FMDV infection regardless of serotype, and thus affect the eradication of FMDV. The present invention also relates to the peptides used in the compositions, and to immunoassays and/or diagnostic kits containing one or more of these peptides, and methods of diagnosing FMDV in mammals using such materials.
摘要翻译：本发明涉及肽组合物作为免疫原的用途，其中包含其中的每种肽包含源自口蹄疫病毒（FMDV）的VP1衣壳蛋白的靶抗原位点。抗原位点与辅助T细胞表位共价连接，优选与其他免疫刺激序列共价连接，优选通过直接合成的常规肽键来预防FMDV感染和根除口蹄疫（FMD））。更具体地，本发明涉及这样的肽组合物作为免疫原在动物中引起生产的用途，包括猪，牛，绵羊，山羊和易感野生物种，高滴度多克隆抗体，其能够在体外有效中和多重 FMDV的菌株或血清型，以及使用这样的组合物作为疫苗来预防和/或降低FMDV感染的发生率，而不管血清型如何，从而影响消除FMDV。本发明还涉及组合物中使用的肽，以及含有这些肽中的一种或多种的免疫测定和/或诊断试剂盒，以及使用这些材料诊断哺乳动物中FMDV的方法。

4. 发明授权

US4835060A Electrical connector 失效
标题翻译：电连接器
公开(公告)号：US4835060A
公开(公告)日：1989-05-30
申请号：US97509
申请日：1987-09-16
申请人： Joseph P. Kosiarski , Ming Shen
发明人： Joseph P. Kosiarski , Ming Shen
IPC分类号： H01R13/24
CPC分类号： H01R13/2414 , Y10T29/4921 , Y10T428/31663
摘要： An improved electrical connector which has improved durability and stability when exposed to low temperature the connector comprises alternating layers of electrically conductive and non-conductive material. The electrically conductive and non-conductive layers each include a silicone-containing material of the formula: ##STR1## wherein R.sub.1 is methyl, vinyl, or phenyl, R.sub.2 is methyl or vinyl, and X+Y+Z equals 0 to about 2 million.
摘要翻译：一种改进的电连接器，其在暴露于低温时具有改善的耐久性和稳定性，所述连接器包括交替的导电和非导电材料层。导电层和非导电层各自包含下式的含硅氧烷材料：其中R1为甲基，乙烯基或苯基，R2为甲基或乙烯基，X + Y + Z为0至约2百万。

5. 发明申请

US20130052134A1 PEG-PLGA-PLL POLYMER AND METHOD FOR PREPARING AND USING THE SAME AS THE DRUG AND GENE CARRIER 审中-公开
标题翻译： PEG-PLGA-PLL聚合物及其制备和使用其作为药物和基因载体的方法
公开(公告)号：US20130052134A1
公开(公告)日：2013-02-28
申请号：US13518874
申请日：2010-12-28
申请人： Yourong Duan , Peifeng Liu , Ying Sun , Ming Shen , Mingjie Zhu , Yanming Sun , Qi Wang , Zelai He , Liubin Qin , Hui Yu , Xiaoyu Li , Xuelian Qi , Xiaoyan Chen , Qiufen Sun , Bingwu Wang
发明人： Yourong Duan , Peifeng Liu , Ying Sun , Ming Shen , Mingjie Zhu , Yanming Sun , Qi Wang , Zelai He , Liubin Qin , Hui Yu , Xiaoyu Li , Xuelian Qi , Xiaoyan Chen , Qiufen Sun , Bingwu Wang
IPC分类号： A61K47/34 , A61K49/00 , C08G63/91 , A61K9/14 , B82Y5/00
CPC分类号： A61K48/0041 , A61K9/5153 , A61K47/62 , A61K47/6935 , C08G63/664 , C08G63/6852 , C08G63/912 , C08G69/10 , C08G69/44 , C08G2261/126 , C12N15/87
摘要： This invention belongs to the nanotechnology field, and discloses a nano drug delivery system with polyethyleneglycol-poly(lactic-co-glycolic acid)-poly-L-lysine (PEG-PLGA-PLL) polymer as the skeleton. The carrier can have the function of passive targeting through control of the carrier particle size. The polymer skeleton is modified through introducing side chains and specific targeting groups, so as to adjust and improve the carrier performance, and enable the carrier to have the function of active targeting. Such carrier material also has the functions of transporting active substances, tumor treatment and diagnosis, ultrasonic contrast, reversing or reducing drug resistance and so on. It is mainly applied to (1) Targeting preparation of anticancer drugs; (2) preparation to reverse or reduce the drug resistance of the tumor; (3) reagent for tumor diagnosis and contrast; (4) reagent to transfect DNA plasmids; (5) pharmaceutical preparation for cancer gene therapy; (6) reagent used to transfect antisense nucleic acid and siRNA (RNA interference); (7) pharmaceutical preparation used to prepare antisense nucleic acid and siRNA (RNA interference).
摘要翻译：本发明属于纳米技术领域，公开了以聚乙二醇 - 聚（乳酸 - 共 - 乙醇酸） - 聚-L-赖氨酸（PEG-PLGA-PLL）聚合物为骨架的纳米药物输送系统。通过控制载体粒径，载体可以具有被动靶向的功能。通过引入侧链和特异性靶向基来改进聚合物骨架，从而调节和改善载体性能，并使载体具有主动靶向功能。这种载体材料还具有运输活性物质，肿瘤治疗和诊断，超声对比，逆转或降低耐药性等功能。主要适用于（1）抗癌药物的靶向制备; （2）准备逆转或降低肿瘤的耐药性; （3）肿瘤诊断试剂和对比剂; （4）转染DNA质粒的试剂; （5）癌基因治疗药物制剂; （6）用于转染反义核酸和siRNA（RNA干扰）的试剂; （7）用于制备反义核酸和siRNA（RNA干扰）的药物制剂。

6. 发明申请

US20110255769A1 MACHINE PERFORMANCE TESTING METHOD AND DEVICE 审中-公开
标题翻译：机械性能测试方法和设备
公开(公告)号：US20110255769A1
公开(公告)日：2011-10-20
申请号：US13086807
申请日：2011-04-14
申请人： Klaus-Peter GALUSCHKI , Yi Hua Gong , Yu Hu , Ming Shen
发明人： Klaus-Peter GALUSCHKI , Yi Hua Gong , Yu Hu , Ming Shen
IPC分类号： G06K9/00 , H04N1/04
CPC分类号： H05K13/00
摘要： A transparent panel is used to acquire a test sample from a machine to be tested; where the test sample includes at least one object placed on the transparent panel by the machine to be tested. A scanning device is used to scan the transparent panel to obtain image data and a computing device is used to determine the operation accuracy of the machine to be tested according to the image data from the scanning device. These devices may be used for machine performance testing and acquiring an image of the test sample.
摘要翻译：透明面板用于从要测试的机器获取测试样品; 其中测试样品包括被待测试机器放置在透明面板上的至少一个物体。扫描装置用于扫描透明面板以获得图像数据，并且使用计算装置根据来自扫描装置的图像数据确定被测试机器的操作精度。这些设备可用于机器性能测试和获取测试样品的图像。

7. 发明申请

US20060156422A1 Methods and compositions for the generation of antibodies 审中-公开
标题翻译：用于产生抗体的方法和组合物
公开(公告)号：US20060156422A1
公开(公告)日：2006-07-13
申请号：US11032668
申请日：2005-01-10
申请人： Michael Dalrymple , Edward Gallagher , Ming Shen , Howard Cooke
发明人： Michael Dalrymple , Edward Gallagher , Ming Shen , Howard Cooke
IPC分类号： A01K67/027 , C12N5/16 , C12N5/06
CPC分类号： A01K67/0271 , A01K2207/15 , A01K2217/00 , A01K2217/075 , A01K2227/105 , A01K2267/01 , C12N2517/02
摘要： The present invention relates to a novel method for the generation of monoclonal antibodies. In particular the invention relates to a novel method for the generation of monoclonal antibodies from non-human somatic transgenic animals. Uses of antibodies generated using the method of the invention are also described.
摘要翻译：本发明涉及产生单克隆抗体的新方法。特别地，本发明涉及从非人体细胞转基因动物产生单克隆抗体的新方法。还描述了使用本发明的方法产生的抗体的用途。

8. 发明授权

US5777178A Process for the preparation of polyoxyalkylene ether surfactant compositions 失效
标题翻译：聚氧化烯表面活性剂组合物的制备方法
公开(公告)号：US5777178A
公开(公告)日：1998-07-07
申请号：US769619
申请日：1996-12-18
申请人： Ming Shen
发明人： Ming Shen
IPC分类号： C07C41/56 , C08G65/331 , C07C41/03
CPC分类号： C08G65/331 , C07C41/56
摘要： The present invention is directed to a process for the preparation of polyoxyalkylene ether surfactant compositions comprising the steps of combining an admixture of alkoxylated alcohols with an acid catalyst and 1-6 molar equivalents of an aldehyde. The mixture is reacted at between about 50.degree. C. and about 180.degree. C. and at between about 1 atm and 10 atm pressure in the absence of a distillation step to produce the polyoxyalkylene ether surfactant composition.
摘要翻译：本发明涉及一种制备聚氧化烯醚表面活性剂组合物的方法，包括以下步骤：将烷氧基化醇的混合物与酸催化剂和1-6摩尔当量的醛组合。在不存在蒸馏步骤的情况下，将混合物在约50℃至约180℃之间和约1atm至10atm压力下反应以产生聚氧化烯醚表面活性剂组合物。

9. 发明授权

US5146011A Preparation of chlorohydrins 失效
标题翻译：氯醇的制备
公开(公告)号：US5146011A
公开(公告)日：1992-09-08
申请号：US718737
申请日：1991-06-21
申请人： Ming Shen , John A. Wojtowicz
发明人： Ming Shen , John A. Wojtowicz
IPC分类号： C07C29/66
CPC分类号： C07C29/66 , C07C2101/14
摘要： Described herein is a process for the preparation of chlorohydrins by reacting a concentrated, aqueous solution of hypochlorous acid with at least one unsaturated organic compound having from 2 to about 10 carbon atoms and selected from the group consisting of substituted or unsubstituted olefins and cyclic olefins.
摘要翻译：本文描述的是通过使浓缩的次氯酸水溶液与至少一种具有2至约10个碳原子并且选自取代或未取代的烯烃和环烯烃的不饱和有机化合物反应来制备氯代醇的方法。

10. 发明授权

US4761447A Heat-vulcanizable moldable/extrudable organopolysiloxane compositions 失效
标题翻译：热可硫化的可成型/可挤出的有机聚硅氧烷组合物
公开(公告)号：US4761447A
公开(公告)日：1988-08-02
申请号：US19949
申请日：1987-02-27
申请人： Ming Shen , Robert Lagarde
发明人： Ming Shen , Robert Lagarde
IPC分类号： C08K13/02 , C08K5/17 , C08L83/04 , C08L83/07 , C08L33/00
CPC分类号： C08K5/17 , C08L83/04 , C08G77/14 , C08G77/16 , C08G77/18 , C08G77/20 , C08G77/24 , C08G77/26 , C08G77/70
摘要： Heat-vulcanizable organopolysiloxane compositions well adopted for extrusion and molding, and facilely converted into elastomeric shaped articles having improved physical and electrical properties, e.g., seals and sections, include a diorganopolysiloxane oil containing from 0.05 to 3 mol % of vinylsiloxy recurring units, as well as an amine having a pKa greater than 7.5 in aqueous solution at 25.degree. C. and a boiling point of less than 270.degree. C. at atmospheric pressure.
摘要翻译：良好地用于挤出和模塑的易于热可聚合的有机基聚硅氧烷组合物，并且易于转化成具有改进的物理和电学性能的弹性成型制品，例如密封件和切片，包括含有0.05至3mol％乙烯基甲硅烷氧基重复单元的二有机聚硅氧烷油作为在25℃的水溶液中的pKa大于7.5并且在大气压下沸点低于270℃的胺。

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