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    • 2. 发明申请
    • Substances for breaking down conformation of microbes
    • 分解微生物构象的物质
    • US20050014830A1
    • 2005-01-20
    • US10860648
    • 2004-06-04
    • Shih LinChih LeeShih LeeShu ChuWen Hsiao
    • Shih LinChih LeeShih LeeShu ChuWen Hsiao
    • A61K31/00A61K31/20
    • A61K31/00A61K31/20
    • A category of substances for inflicting in a biomolecular mechanism the conformation breakdown of microbes into biological components is disclosed. A substance of the category has a chemical composition of hydrophobic nature having bonded to at least one structural point of its composition a hydrophilic functional group. A multiplicity of molecules of the substance inflicts the microbe breakdown by being adsorbed to the microbial surface of the target microbe and assembled into aggregates. The substance molecules' aggregates at close proximity to the microbial surface exert adsorptive interaction forces to nearby ones of the microbe biological components. The forces exerted are significant enough to compete with the absorptive interaction forces among the biological components and thereby disrupts the conformation, breaks out of structural binding equilibrium among the biological components, and results in the breakdown and denaturation of the microbe.
    • 公开了一种用于在生物分子机制中引起微生物构成生物成分的物质的物质。 该类别的物质具有疏水性质的化学组成,其结合至其组成的至少一个结构点为亲水官能团。 该物质的多个分子通过吸附到目标微生物的微生物表面并组装成聚集体而导致微生物分解。 物质分子在微生物表面附近的聚集体向附近的微生物生物成分施加吸附相互作用力。 施加的力足够大以与生物组分中的吸收相互作用力竞争,从而破坏构象,破坏生物组分之间的结构结合平衡,并导致微生物的破坏和变性。