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1. 发明授权

US5457606A Hermetically sealed PC card unit including a header secured to a connector 失效
标题翻译：密封的PC卡单元，包括固定到连接器的插头
公开(公告)号：US5457606A
公开(公告)日：1995-10-10
申请号：US178385
申请日：1993-12-23
申请人： Paul R. Young , Robert Blake , Christopher Staehly , David Richard , Leonard Bazar
发明人： Paul R. Young , Robert Blake , Christopher Staehly , David Richard , Leonard Bazar
IPC分类号： G06K19/077 , H05K5/02 , H05K1/18 , H01R13/58 , H01R23/70 , H05K5/06
CPC分类号： H05K5/0269 , G06K19/077 , G06K19/07743
摘要： An improved PC Card element, particularly a flash card unit, is presented in which the unit is hermetically sealed. The unit has a metallic frame, a metallic header with glass or ceramic encapsulated through pins, and opposed outer metallic covers, all of the metallic elements being of the same metal and being welded together to form a hermetically sealed unit.
摘要翻译：提出了一种改进的PC卡元件，特别是闪存卡单元，其中该单元被气密密封。该单元具有金属框架，具有通过销钉封装的玻璃或陶瓷的金属集管和相对的外部金属盖，所有金属元件都是相同的金属并且被焊接在一起以形成气密密封的单元。

2. 发明授权

US09051305B2 Compositions and methods useful for treating diseases 有权
标题翻译：用于治疗疾病的组合物和方法
公开(公告)号：US09051305B2
公开(公告)日：2015-06-09
申请号：US14003733
申请日：2012-03-08
申请人： Michael H. Cardone , Andrew F. Kolodziej , David Richard
发明人： Michael H. Cardone , Andrew F. Kolodziej , David Richard
IPC分类号： A61K31/04 , C07D215/38 , C07D401/14 , C07D405/14 , C07D417/14
CPC分类号： A61K31/4709 , A61K31/496 , C07D401/14 , C07D405/14 , C07D417/14
摘要： The present invention relates to a compositions for and methods of cancer treatment in which compounds of Formula I or Formula II. In some aspects, the treatment of B-cell Lymphoma or other hematopoietic cancers is encompassed. In other aspects, the invention provides methods for treating particular types of hematopoietic cancers, such as B-cell lymphoma, using a combination of one or more compounds of Formula I or Formula II. Combination therapy with, for example, a class of therapeutics known as 26S proteasome inhibitors, for example, Bortezomib, are also included. In another aspect the present invention relates to autoimmune treatment with compounds of Formula I or Formula II. In another aspect, this invention relates to methods for identifying compounds, for example, compounds of the BH3 mimic class, that have unique in vitro properties that predict in vivo efficacy against B-cell lymphoma tumors and other cancers as well as autoimmune disease.
摘要翻译：本发明涉及式I或式II化合物的癌症治疗用组合物和方法。在一些方面，包括B细胞淋巴瘤或其他造血癌的治疗。在其它方面，本发明提供了使用一种或多种式I或式II化合物的组合来治疗特定类型的造血细胞癌例如B细胞淋巴瘤的方法。还包括与例如称为26S蛋白酶体抑制剂的一类治疗剂例如硼替佐米的组合疗法。另一方面，本发明涉及用式I或式II化合物进行的自身免疫治疗。在另一方面，本发明涉及用于鉴定化合物的方法，例如BH3类似物的化合物，其具有独特的体外性质，其预测体内对B细胞淋巴瘤肿瘤和其他癌症以及自身免疫疾病的功效。

3. 发明申请

US20140160900A1 FUNCTIONAL MICROMECHANICAL ASSEMBLY 有权
标题翻译：功能微生物装置
公开(公告)号：US20140160900A1
公开(公告)日：2014-06-12
申请号：US14233303
申请日：2012-07-17
申请人： David Richard , Stewes Bourban
发明人： David Richard , Stewes Bourban
IPC分类号： G04B15/14 , G04B13/02 , G04B31/004 , G04B1/14
CPC分类号： G04B13/02 , B81B2201/035 , B81C99/0095 , C10M2201/041 , C23C16/26 , C23C16/27 , G04B1/14 , G04B1/145 , G04B13/022 , G04B15/14 , G04B31/004 , G04B31/08
摘要： A functional micromechanical timepiece assembly including at least a first component, including a first layer defining a first contact surface configured to come into friction contact with a second contact surface defined by a second layer, the second layer belonging, either to the first component, or to at least a second micromechanical component forming the assembly with the first component. The first and second layers each include carbon with at least 50% carbon atoms and, on the first and second contact surfaces, the layers have different surface crystalline plane orientations from each other.
摘要翻译：一种功能微机械钟表组件，其至少包括第一部件，所述第一部件包括限定第一接触表面的第一层，所述第一接触表面被构造成与由第二层限定的第二接触表面摩擦接触，所述第二层属于第一部件，至少第二微机械部件与第一部件形成组件。第一层和第二层各自包含具有至少50％碳原子的碳，并且在第一和第二接触表面上，这些层具有彼此不同的表面晶面取向。

4. 发明申请

US20150003215A1 METHOD FOR CREATING A COMPONENT 有权
标题翻译：创建组件的方法
公开(公告)号：US20150003215A1
公开(公告)日：2015-01-01
申请号：US14367655
申请日：2012-12-20
申请人： Thierry Hessler , Nicolas Rebeaud , Jean-Luc Helfer , David Richard , Sebastien Graf
发明人： Thierry Hessler , Nicolas Rebeaud , Jean-Luc Helfer , David Richard , Sebastien Graf
IPC分类号： G04B31/06 , G04B15/14 , G04B31/08 , G04B31/004 , G04D3/00 , B23K26/00
CPC分类号： G04B31/06 , B23K26/57 , F16C17/03 , F16C17/06 , F16C33/10 , G04B15/14 , G04B31/00 , G04B31/004 , G04B31/02 , G04B31/08 , G04D3/0069 , G04D3/0071
摘要： A method for manufacturing a component in a substrate including: a) modifying a structure of at least one region of the substrate to make the at least one region more selective; and b) chemically etching the at least one region to selectively manufacture the component.
摘要翻译：一种用于制造衬底中的部件的方法，包括：a）修改所述衬底的至少一个区域的结构，以使所述至少一个区域更具选择性; 以及b）化学蚀刻所述至少一个区域以选择性地制造所述部件。

5. 发明申请

US20120051192A1 METHOD FOR COATING MICROMECHANICAL PARTS WITH HIGH TRIBOLOGICAL PERFORMANCES FOR APPLICATION IN MECHANICAL SYSTEMS 失效
标题翻译：用于机械系统应用的具有高度TRIBOLOGICAL性能的微生物部件的涂覆方法
公开(公告)号：US20120051192A1
公开(公告)日：2012-03-01
申请号：US13319446
申请日：2010-05-18
申请人： Detlef Steinmuller , Doris Steinmuller , Herwig Drexel , Slimane Ghodbane , David Richard , Pierre Cusin
发明人： Detlef Steinmuller , Doris Steinmuller , Herwig Drexel , Slimane Ghodbane , David Richard , Pierre Cusin
IPC分类号： G04B15/00 , C23C16/52
CPC分类号： C23C16/279 , C23C16/26 , C23C16/271 , G04B13/02 , G04B15/14 , G04D3/0069
摘要： Method for coating micromechanical components of a micromechanical system, in particular a watch movement, comprising: providing a substrate component to be coated; providing said component with a diamond coating; wherein diamond coating is provide by CVD in a reaction chamber and during CVD deposition, during the last portion of the growth process, a controlled change of the carbon content within the reaction chamber is provided, thereby providing a change of the sp2/sp3 carbon bonds in the vicinity of the surface. Corresponding micromechanical components are also provided.
摘要翻译：用于涂覆微机械系统的微机械部件的方法，特别是手表机芯，包括：提供待涂覆的基底部件; 向所述部件提供金刚石涂层; 其中通过CVD在反应室中和在CVD沉积期间提供金刚石涂层，在生长过程的最后部分期间，提供反应室内碳含量的受控变化，从而提供sp2 / sp3碳键的改变在表面附近。还提供了相应的微机械部件。

6. 发明授权

US08770827B2 Method for coating micromechanical parts with high tribological performances for application in mechanical systems 失效
标题翻译：用于涂覆机械系统中具有高摩擦学性能的微机械零件的方法
公开(公告)号：US08770827B2
公开(公告)日：2014-07-08
申请号：US13319446
申请日：2010-05-18
申请人： Detlef Steinmuller , Doris Steinmuller , Herwig Drexel , Slimane Ghodbane , David Richard , Pierre Cusin
发明人： Detlef Steinmuller , Doris Steinmuller , Herwig Drexel , Slimane Ghodbane , David Richard , Pierre Cusin
IPC分类号： G04B15/00 , C23C16/52
CPC分类号： C23C16/279 , C23C16/26 , C23C16/271 , G04B13/02 , G04B15/14 , G04D3/0069
摘要： Method for coating micromechanical components of a micromechanical system, in particular a watch movement, comprising: providing a substrate component to be coated; providing said component with a diamond coating; wherein diamond coating is provide by CVD in a reaction chamber and during CVD deposition, during the last portion of the growth process, a controlled change of the carbon content within the reaction chamber is provided, thereby providing a change of the sp2/sp3 carbon bonds in the vicinity of the surface. Corresponding micromechanical components are also provided.
摘要翻译：用于涂覆微机械系统的微机械部件的方法，特别是手表机芯，包括：提供待涂覆的基底部件; 向所述部件提供金刚石涂层; 其中通过CVD在反应室中和在CVD沉积期间提供金刚石涂层，在生长过程的最后部分期间，提供反应室内碳含量的受控变化，从而提供sp2 / sp3碳键的改变在表面附近。还提供了相应的微机械部件。

7. 发明申请

US20070193750A1 Apparatus for handling and racking pipes 有权
标题翻译：用于处理和堆放管道的装置
公开(公告)号：US20070193750A1
公开(公告)日：2007-08-23
申请号：US11785446
申请日：2007-04-18
申请人： Monte Wright , William Stroshein , David Richard , Andrew Banister
发明人： Monte Wright , William Stroshein , David Richard , Andrew Banister
IPC分类号： E21B19/00
CPC分类号： E21B19/20 , E21B19/14
摘要： An apparatus and method for handling pipes in a derrick and racking the pipes on a pipe racking assembly mounted on the derrick. The apparatus includes a rotatable gate assembly rotatably mounted on the pipe racking assembly. The rotatable gate assembly includes a collar rotatably mounted to a first end of a rotatable pipe support. A pipe manipulator arm is pivotably mounted on a second end of the rotatable gate assembly. The collar defines a gate for securing an upper portion of the pipe stand. A pipe mount is mounted to a distal end of the arm for holding the pipe stand for transport between the derrick and the gate, and between the gate and the pipe rack. After the arm secures the pipe stand into the gate from the derrick, a drive mechanism rotates the rotatable gate assembly to a rack facing position from the derrick facing position such that the arm may transport the pipe between the gate and the pipe rack.
摘要翻译：一种用于在井架中处理管道的装置和方法，并且将安装在井架上的管道组件上的管道装卸。该装置包括可旋转地安装在管道支架组件上的可旋转门组件。可旋转门组件包括可旋转地安装到可旋转管支撑件的第一端的轴环。管状操纵臂可枢转地安装在可旋转门组件的第二端上。套环定义一个用于固定管架上部的门。管座安装在臂的远端，用于保持管架在井架和闸门之间以及门和管架之间运输。在臂将管架从井架固定到闸门中之后，驱动机构将可旋转闸门组件从面向井架的位置旋转到面向机架的位置，使得臂可以在管道和管架之间输送管道。

8. 发明申请

US20060087755A1 Transparent plastic optical components and abrasion resistant polymer substrates and methods for making the same 审中-公开
公开(公告)号：US20060087755A1
公开(公告)日：2006-04-27
申请号：US11297493
申请日：2005-12-08
申请人： David Richard
发明人： David Richard
IPC分类号： G02B5/08
CPC分类号： G02B5/0883 , B32B27/08 , G02B5/0841 , G02B5/0866
摘要： A polymer-based component formed from a synthetic thermoplastic or thermoset resin substrate, such as polymethyl methacrylate, which is resistant to warping and distortion from moisture. A composite multi-layer surface-hardening coating is formed on at least the anterior surface of the resin substrate. The component can include a composite multi-layer reflective coating to form a mirror. A protective back-coat layer is deposited on a posterior surface of the mirror. A multi-layer weather-resistant coating may optionally be applied to the anterior surface of the polymer-based mirror in order to increase the weatherability and durability of the mirror. The various layers coating the synthetic resin substrate have their moisture permeabilities selected so that substantially equal amounts of moisture permeate through to both the anterior and posterior side of the synthetic resin substrate. A sol-gel coating can be used to deposit the multi-layers in a single step by providing gradient zones of zirconia/silica while enabling a hydrophobic or a hydrophilic exterior surface.

9. 发明申请

US20060070078A1 Systems and methods to allocate application tasks to a pool of processing machines 有权
公开(公告)号：US20060070078A1
公开(公告)日：2006-03-30
申请号：US11208991
申请日：2005-08-22
申请人： Jay Dweck , Michael Fellows , David Richard , Mark Morrissey , Marry Byron
发明人： Jay Dweck , Michael Fellows , David Richard , Mark Morrissey , Marry Byron
IPC分类号： G06F9/46 , G06F15/16 , G06F15/173
CPC分类号： G06F9/50 , G06F9/5027 , G06F2209/5011 , G06F2209/5014 , G06F2209/5017 , H04L67/10
摘要： Systems and methods are provided to allocate application tasks to a pool of processing machines. According to some embodiments, a requestor generates a scope request including an indication of a number of compute units to be reserved. The requestor also provides an application request associated with the scope. A subset of available processing machines may then be allocated to the scope, and the application request is divided into a number of different tasks. Each task may then be assigned to a processing machine that has been allocated to the application request. According to some embodiments, each task is associated with a deadline. Moreover, according to some embodiments an overall cost is determined and then allocated to the requestor based on the number of compute units that were reserved for the scope.

10. 发明申请

US20050010693A1 Connection manager and methods of connection management 有权
标题翻译：连接管理器和连接管理方法
公开(公告)号：US20050010693A1
公开(公告)日：2005-01-13
申请号：US10616515
申请日：2003-07-09
申请人： Hunter Sinclair , Adam Klein , James Grantges , John Crane , Abel Law , Nicholas Macron , Nishant Jain , David Richard
发明人： Hunter Sinclair , Adam Klein , James Grantges , John Crane , Abel Law , Nicholas Macron , Nishant Jain , David Richard
IPC分类号： G06F15/16 , G09G5/00 , H04L12/28 , H04L29/08
CPC分类号： H04L12/2856 , H04L12/2876 , H04L67/36
摘要： The disclosure is directed to a connection manager that includes a dialer configured to interact with a modem to provide a connection to a service provider. The connection manager includes a graphical user interface and an advice window. The graphical user interface is configured to manipulate parameters associated with the connection. The graphical user interface includes a form component. The advice window is responsive to user actions associated with the form component.
摘要翻译：本公开涉及一种连接管理器，其包括被配置为与调制解调器交互以提供到服务提供商的连接的拨号器。连接管理器包括图形用户界面和通知窗口。图形用户界面被配置为操纵与连接相关联的参数。图形用户界面包括一个表单组件。通知窗口响应于与表单组件相关联的用户操作。

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