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1. 发明授权

US08882762B2 Transmural ablation device 有权
标题翻译：跨膜消融装置
公开(公告)号：US08882762B2
公开(公告)日：2014-11-11
申请号：US13512493
申请日：2010-11-30
申请人： Paul J Wang , Amin Al-Ahmad , William Francis Johnston , Kai Ihnken , Kaartiga Sivanesan , Morgan Clyburn , Kathleen Lee Kang , Lauren Shui Sum Chan , Robert C Robbins , Friedrich B. Prinz
发明人： Paul J Wang , Amin Al-Ahmad , William Francis Johnston , Kai Ihnken , Kaartiga Sivanesan , Morgan Clyburn , Kathleen Lee Kang , Lauren Shui Sum Chan , Robert C Robbins , Friedrich B. Prinz
IPC分类号： A61B18/18 , A61N2/00 , A61B18/14 , A61B17/00 , A61B18/00 , A61B19/00
CPC分类号： A61B18/1492 , A61B18/14 , A61B34/73 , A61B2017/00876 , A61B2018/00005 , A61B2018/00291 , A61B2018/00363 , A61B2018/00577
摘要： A transmural ablation device is provided to achieve endocardial and epicardial ablation at the same site but directed from the inner and outer surfaces of the heart to create a transmural lesion. By ablating from both sides of the heart tissue, it is possible to increase the depth of the lesion created and to increase the likelihood of a transmural lesion. Embodiments pertain to techniques to align the endocardial and epicardial ablation elements and techniques to position and move the endocardial and epicardial ablation elements along a predefined linear, curvilinear, or circular path. The ability to bring the epicardial and endocardial elements more closely or firmly with the underlying tissue is important in creating optimal lesions. Magnetic force attracts the epicardial and endocardial elements.
摘要翻译：提供透壁消融装置以在相同部位实现心内膜和心外膜消融，但是从心脏的内表面和外表面引导以产生透壁病变。通过从心脏组织的两侧烧蚀，可以增加所产生的损伤的深度并增加透壁病变的可能性。实施例涉及用于对准心内膜和心外膜消融元件和技术以沿着预定义的线性，曲线或圆形路径定位和移动心内膜和心外膜消融元件的技术。使心外膜和心内膜元件与下面的组织更紧密或更牢固的能力对于创建最佳损伤是重要的。磁力吸引心外膜和心内膜元件。

2. 发明申请

US20130131665A1 Transmural Ablation Device 有权
标题翻译：透壁消融装置
公开(公告)号：US20130131665A1
公开(公告)日：2013-05-23
申请号：US13512493
申请日：2010-11-30
申请人： Paul J. Wang , Amin Al-Ahmad , William Francis Johnston , Kai Ihnken , Kaartiga Sivanesan , Morgan Clyburn , Kathleen Lee Kang , Lauren Shui Sum Chan , Robert C. Robbins , Friedrich B. Prinz
发明人： Paul J. Wang , Amin Al-Ahmad , William Francis Johnston , Kai Ihnken , Kaartiga Sivanesan , Morgan Clyburn , Kathleen Lee Kang , Lauren Shui Sum Chan , Robert C. Robbins , Friedrich B. Prinz
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B18/14 , A61B34/73 , A61B2017/00876 , A61B2018/00005 , A61B2018/00291 , A61B2018/00363 , A61B2018/00577
摘要： A transmural ablation device is provided to achieve endocardial and epicardial ablation at the same site but directed from the inner and outer surfaces of the heart to create a transmural lesion. By ablating from both sides of the heart tissue, it is possible to increase the depth of the lesion created and to increase the likelihood of a transmural lesion. Embodiments pertain to techniques to align the endocardial and epicardial ablation elements and techniques to position and move the endocardial and epicardial ablation elements along a predefined linear, curvilinear, or circular path. The ability to bring the epicardial and endocardial elements more closely or firmly with the underlying tissue is important in creating optimal lesions. Magnetic force attracts the epicardial and endocardial elements.
摘要翻译：提供透壁消融装置以在相同部位实现心内膜和心外膜消融，但是从心脏的内表面和外表面引导以产生透壁病变。通过从心脏组织的两侧烧蚀，可以增加所产生的损伤的深度并增加透壁病变的可能性。实施例涉及用于对准心内膜和心外膜消融元件和技术以沿着预定义的线性，曲线或圆形路径定位和移动心内膜和心外膜消融元件的技术。使心外膜和心内膜元件与下面的组织更紧密或更牢固的能力对于创建最佳损伤是重要的。磁力吸引心外膜和心内膜元件。

3. 发明申请

US20090281534A1 SYSTEM FOR DELIVERING THERAPY 有权
标题翻译：传递治疗系统
公开(公告)号：US20090281534A1
公开(公告)日：2009-11-12
申请号：US12119442
申请日：2008-05-12
申请人： Friedrich B. Prinz , Paul J. Wang , Bryant Y. Lin , Ross Venook
发明人： Friedrich B. Prinz , Paul J. Wang , Bryant Y. Lin , Ross Venook
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/1861
摘要： The system of the preferred embodiments includes a first rotational element, a second rotational element, and a therapeutic source coupled to the rotational elements. The system permits simultaneous attachment to and movement around a surface of tissue, preferably during an ablation procedure (either during lesion creation or between lesion creation events), or during any other suitable procedure. The therapeutic source functions to translate along the path of tissue and deliver therapy as the first and second rotational elements rotate and roll along the path of tissue. The therapeutic source preferably delivers contiguous doses of therapy along the path of tissue. The system is preferably designed for delivering therapy to tissue and, more specifically, for delivering therapy to cardiac tissue. The system, however, may be alternatively used in any suitable environment and for any suitable reason.
摘要翻译：优选实施例的系统包括耦合到旋转元件的第一旋转元件，第二旋转元件和治疗源。该系统允许同时附着于组织表面并且围绕组织表面移动，优选地在消融过程期间（在损伤创建期间或在损伤创建事件之间）或在任何其它合适的过程期间。当第一和第二旋转元件沿着组织的路径旋转和滚动时，治疗源用于沿着组织的路径平移并递送治疗。治疗源优选沿着组织的路径递送连续剂量的治疗。该系统优选地被设计用于递送治疗组织，更具体地，用于将治疗递送到心脏组织。然而，该系统可以替代地在任何合适的环境中使用，并且出于任何合适的原因。

4. 发明授权

US08100900B2 System for delivering therapy 有权
标题翻译：治疗系统
公开(公告)号：US08100900B2
公开(公告)日：2012-01-24
申请号：US12119442
申请日：2008-05-12
申请人： Friedrich B. Prinz , Paul J. Wang , Bryant Y Lin , Ross Venook
发明人： Friedrich B. Prinz , Paul J. Wang , Bryant Y Lin , Ross Venook
IPC分类号： A61B18/14 , A61B18/02
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/1861
摘要： The system of the preferred embodiments includes a first rotational element, a second rotational element, and a therapeutic source coupled to the rotational elements. The system permits simultaneous attachment to and movement around a surface of tissue, preferably during an ablation procedure (either during lesion creation or between lesion creation events), or during any other suitable procedure. The therapeutic source functions to translate along the path of tissue and deliver therapy as the first and second rotational elements rotate and roll along the path of tissue. The therapeutic source preferably delivers contiguous doses of therapy along the path of tissue. The system is preferably designed for delivering therapy to tissue and, more specifically, for delivering therapy to cardiac tissue. The system, however, may be alternatively used in any suitable environment and for any suitable reason.
摘要翻译：优选实施例的系统包括耦合到旋转元件的第一旋转元件，第二旋转元件和治疗源。该系统允许同时附着于组织表面并且围绕组织表面移动，优选地在消融过程期间（在损伤创建期间或在损伤创建事件之间）或在任何其它合适的过程期间。当第一和第二旋转元件沿着组织的路径旋转和滚动时，治疗源用于沿着组织的路径平移并递送治疗。治疗源优选沿着组织的路径递送连续剂量的治疗。该系统优选地被设计用于递送治疗组织，更具体地，用于将治疗递送到心脏组织。然而，该系统可以替代地在任何合适的环境中使用，并且出于任何合适的原因。

5. 发明授权

US08951605B2 Thin film MEA structures for fuel cell and method for fabrication 有权
标题翻译：用于燃料电池的薄膜MEA结构及其制造方法
公开(公告)号：US08951605B2
公开(公告)日：2015-02-10
申请号：US12589857
申请日：2009-10-28
申请人： Friedrich B. Prinz , Turgut M. Gür
发明人： Friedrich B. Prinz , Turgut M. Gür
IPC分类号： B05D5/12 , H01M8/10 , C25B9/10
CPC分类号： H01M8/1006 , C25B9/10 , Y02E60/521
摘要： The current invention provides a fabrication method for large surface area, pinhole-free, ultra thin ion conducting membranes using atomic layer deposition on inexpensive sacrificial substrates to make cost effective, high performance fuel cells or electrolyzers. The resultant membrane electrode assembly (MEA) enables significant reduction in resistive losses as well as lowering of the operating temperature of the fuel cell. The invention further provides a method to deposit 3-dimensional surface conformal films that may have compositional grading for superior performance. In addition, the invention provides decoration and modification of electrode surfaces for enhanced catalytic activity and reduced polarization losses. The method of the current invention enables the MEA structure to be fabricated from the anode side up or the cathode side up, each with or without an incorporated anode current collector or cathode current collector, respectively.
摘要翻译：本发明提供了一种用于大面积，无针孔，超薄离子导电膜的制造方法，其使用廉价的牺牲基板上的原子层沉积来制造成本有效的高性能燃料电池或电解器。所得的膜电极组件（MEA）能够显着降低电阻损耗以及降低燃料电池的工作温度。本发明还提供一种沉积可具有优异性能的组成分级的三维表面保形膜的方法。此外，本发明提供电极表面的装饰和修改，以增强催化活性和降低极化损失。本发明的方法使得能够从阳极侧向上或阴极侧向上制造MEA结构，每个具有或不具有并入的阳极集电器或阴极集电器。

6. 发明授权

US08496999B2 Field-aided preferential deposition of precursors 失效
标题翻译：现场辅助优先沉积前体
公开(公告)号：US08496999B2
公开(公告)日：2013-07-30
申请号：US12383588
申请日：2009-03-24
申请人： Neil Dasgupta , Friedrich B. Prinz , Timothy P. Holme , Stephen Walch , Wonyoung Lee , James F. Mack
发明人： Neil Dasgupta , Friedrich B. Prinz , Timothy P. Holme , Stephen Walch , Wonyoung Lee , James F. Mack
IPC分类号： C23C16/02
CPC分类号： C23C16/047 , C23C16/45536 , C23C16/45544 , G01Q30/02 , G01Q80/00
摘要： Area selective atomic layer deposition is provided by a method including the following steps. First, a substrate is provided. Second, a tip of a scanning probe microscope (SPM) is disposed in proximity to the surface of the substrate. An electrical potential is then established between the tip and the surface that cause one or more localized electrical effects in proximity to the tip. Deposition reactants for atomic layer deposition (ALD) are provided, and deposition occurs in a pattern defined by the localized electrical effects because of locally enhanced ALD reaction rates.
摘要翻译：通过包括以下步骤的方法提供区域选择性原子层沉积。首先，提供基板。其次，扫描探针显微镜（SPM）的尖端设置在基板的表面附近。然后在尖端和表面之间建立电位，导致在尖端附近产生一个或多个局部电效应。提供用于原子层沉积（ALD）的沉积反应物，并且由于局部增强的ALD反应速率，由局部电效应限定的图案沉积。

7. 发明授权

US08347738B2 Sensors and control for an interventional catheter 有权
公开(公告)号：US08347738B2
公开(公告)日：2013-01-08
申请号：US12151963
申请日：2008-05-09
申请人： Alexander Tung , Günter Niemeyer , David Liang , Byong-Ho Park , Friedrich B. Prinz , Bob S. Hu
发明人： Alexander Tung , Günter Niemeyer , David Liang , Byong-Ho Park , Friedrich B. Prinz , Bob S. Hu
IPC分类号： G01L1/22
CPC分类号： A61B5/103 , A61B5/6852 , A61B5/6885 , A61B5/7455 , A61B2034/2061 , A61B2562/0252 , A61B2562/0261 , A61B2562/0266 , A61B2562/043
摘要： This invention provides small position sensors for applications where localized sensing in a small volume of space is needed but where measurement of large relative displacement is also necessary. The invention enables a surgeon to accurately position the tip of a catheter during minimally invasive therapy. The current invention further improves the quality of tactile feedback to a physician during catheter-based surgeries with an axial force sensor at the tip of the catheter that allows for the transmission of force information to the physician. One embodiment of this invention is a position sensor for active interventional catheters, where the sensor may be laser-machined shape memory alloy (SMA), and the catheter actuators may be heated SMA or wire-pulleys. Providing position feedback from a catheter during minimally invasive therapy allows for closed-loop control of the catheter tip position under computer-aided guidance and enable force feedback to the physician.

8. 发明申请

US20100255406A1 SOLID-STATE FUEL CELL INCLUDING CHEMICAL ELECTROLYTE PROTECTION LAYER AND METHOD OF MANUFACTURING SAME 有权
标题翻译：固体燃料电池，包括化学电解质保护层及其制造方法
公开(公告)号：US20100255406A1
公开(公告)日：2010-10-07
申请号：US12417095
申请日：2009-04-02
申请人： SangKyun Kang , Joonhyung Shim , Friedrich B. Prinz , Turuot M. Gor
发明人： SangKyun Kang , Joonhyung Shim , Friedrich B. Prinz , Turuot M. Gor
IPC分类号： H01M8/10
CPC分类号： H01M8/1213 , H01M4/8657 , H01M4/8663 , H01M2008/1293 , H01M2300/0074 , Y02P70/56 , Y10T29/49115
摘要： A solid-state fuel cell includes: an anode; an anode side chemical electrolyte protection layer disposed on the anode; a hydrogen ion conductive solid oxide film disposed on the anode side chemical electrolyte protection layer; a cathode side chemical electrolyte protection layer disposed on the hydrogen ion conductive solid oxide film; and a cathode disposed on the cathode side chemical electrolyte protection layer.
摘要翻译：固态燃料电池包括：阳极; 设置在阳极上的阳极侧化学电解质保护层; 设置在阳极侧化学电解质保护层上的氢离子导电固体氧化物膜; 设置在氢离子导电固体氧化物膜上的阴极侧化学电解质保护层; 阴极配置在阴极侧的化学电解质保护层。

9. 发明申请

US20100183919A1 Quantum dot ultracapacitor and electron battery 有权
标题翻译：量子点超级电容器和电子电池
公开(公告)号：US20100183919A1
公开(公告)日：2010-07-22
申请号：US12657198
申请日：2010-01-15
申请人： Timothy P. Holme , Friedrich B. Prinz
发明人： Timothy P. Holme , Friedrich B. Prinz
IPC分类号： H01M4/02
CPC分类号： B82Y10/00 , B82Y30/00 , H01L28/40 , H01L29/127
摘要： The present invention provides a solid-state energy storage device having at least one quantum confinement species (QCS), where the QCS can include a quantum dot (QD), quantum well, or nanowire. The invention further includes at least one layer of a dielectric material with at least one QCS incorporated there to, and a first conductive electrode disposed on a top surface of the at least one layer of the dielectric material, and a second conductive electrode is disposed on a bottom surface of the at least one layer of dielectric material, where the first electrode and the second electrode are disposed to transfer a charge to the at least one QCS, where when an electrical circuit is disposed to provide an electric potential across the first electrode and the second electrode, the electric potential discharges the transferred charge from the at least one QCS to the electrical circuit.
摘要翻译：本发明提供一种具有至少一个量子限制物质（QCS）的固态储能装置，其中QCS可以包括量子点（QD），量子阱或纳米线。本发明还包括至少一层电介质材料，其中结合有至少一个QCS，以及设置在电介质材料的至少一层的顶表面上的第一导电电极，第二导电电极设置在所述至少一层介电材料的底表面，其中所述第一电极和所述第二电极被设置成将电荷转移到所述至少一个QCS，其中当设置电路以在所述第一电极上提供电位时和所述第二电极，所述电位将所传送的电荷从所述至少一个QCS放电至所述电路。

10. 发明申请

US20100112196A1 Thin film MEA structures for fuel cell and method for fabrication 有权
标题翻译：用于燃料电池的薄膜MEA结构及其制造方法
公开(公告)号：US20100112196A1
公开(公告)日：2010-05-06
申请号：US12589857
申请日：2009-10-28
申请人： Friedrich B. Prinz , Turgut M. Gür
发明人： Friedrich B. Prinz , Turgut M. Gür
IPC分类号： H01M8/10
CPC分类号： H01M8/1006 , C25B9/10 , Y02E60/521
摘要： The current invention provides a fabrication method for large surface area, pinhole-free, ultra thin ion conducting membranes using atomic layer deposition on inexpensive sacrificial substrates to make cost effective, high performance fuel cells or electrolyzers. The resultant membrane electrode assembly (MEA) enables significant reduction in resistive losses as well as lowering of the operating temperature of the fuel cell. The invention further provides a method to deposit 3-dimensional surface conformal films that may have compositional grading for superior performance. In addition, the invention provides decoration and modification of electrode surfaces for enhanced catalytic activity and reduced polarization losses. The method of the current invention enables the MEA structure to be fabricated from the anode side up or the cathode side up, each with or without an incorporated anode current collector or cathode current collector, respectively.
摘要翻译：本发明提供了一种用于大面积，无针孔，超薄离子导电膜的制造方法，其使用廉价的牺牲基板上的原子层沉积来制造成本有效的高性能燃料电池或电解器。所得的膜电极组件（MEA）能够显着降低电阻损耗以及降低燃料电池的工作温度。本发明还提供一种沉积可具有优异性能的组成分级的三维表面保形膜的方法。此外，本发明提供电极表面的装饰和修改，以增强催化活性和降低极化损失。本发明的方法使得能够从阳极侧向上或阴极侧向上制造MEA结构，每个具有或不具有并入的阳极集电器或阴极集电器。

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