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1. 发明授权

US09451926B2 Respiratory motion correction with internal-external motion correlation, and associated systems and methods 有权
标题翻译：内外部运动相关的呼吸运动校正，以及相关的系统和方法
公开(公告)号：US09451926B2
公开(公告)日：2016-09-27
申请号：US13891083
申请日：2013-05-09
申请人： Paul E. Kinahan , Adam Alessio , Chi Liu
发明人： Paul E. Kinahan , Adam Alessio , Chi Liu
IPC分类号： A61B5/05 , A61B6/00 , A61B6/03
CPC分类号： A61B6/527 , A61B6/032 , A61B6/037 , A61B6/5235 , A61B6/5264 , A61B6/541
摘要： The present technology relates generally to respiratory motion correction and associated systems and methods. In particular, several embodiments are directed to respiratory motion correction using internal-external motion correlation. For example, one embodiment of a method of correcting motion blurring in PET/CT imaging includes obtaining PET/CT imaging data of a target tissue in a patient and determining a centroid of the target tissue. The method can further include obtaining an external motion signal of the patient and determining a mean displacement of the external motion signal. The centroid of the target tissue can be correlated with the mean displacement and, based on the correlation, a PET/CT image corrected for motion of the target tissue can be reconstructed.
摘要翻译：本技术一般涉及呼吸运动校正及相关系统和方法。特别地，几个实施例涉及使用内部 - 外部运动相关的呼吸运动校正。例如，在PET / CT成像中校正运动模糊的方法的一个实施例包括获得患者中目标组织的PET / CT成像数据并确定目标组织的质心。该方法还可以包括获得患者的外部运动信号并确定外部运动信号的平均位移。目标组织的质心可以与平均位移相关，并且基于相关性可以重建针对目标组织运动的PET / CT图像。

2. 发明申请

US20130303898A1 RESPIRATORY MOTION CORRECTION WITH INTERNAL-EXTERNAL MOTION CORRELATION, AND ASSOCIATED SYSTEMS AND METHODS 有权
标题翻译：呼吸运动校正与内外运动相关性及相关系统与方法
公开(公告)号：US20130303898A1
公开(公告)日：2013-11-14
申请号：US13891083
申请日：2013-05-09
申请人： Paul E. Kinahan , Adam Alessio , Chi Liu
发明人： Paul E. Kinahan , Adam Alessio , Chi Liu
IPC分类号： A61B6/00 , A61B6/03
CPC分类号： A61B6/527 , A61B6/032 , A61B6/037 , A61B6/5235 , A61B6/5264 , A61B6/541
摘要： The present technology relates generally to respiratory motion correction and associated systems and methods. In particular, several embodiments are directed to respiratory motion correction using internal-external motion correlation. For example, one embodiment of a method of correcting motion blurring in PET/CT imaging includes obtaining PET/CT imaging data of a target tissue in a patient and determining a centroid of the target tissue. The method can further include obtaining an external motion signal of the patient and determining a mean displacement of the external motion signal. The centroid of the target tissue can be correlated with the mean displacement and, based on the correlation, a PET/CT image corrected for motion of the target tissue can be reconstructed.
摘要翻译：本技术一般涉及呼吸运动校正及相关系统和方法。特别地，几个实施例涉及使用内部 - 外部运动相关的呼吸运动校正。例如，在PET / CT成像中校正运动模糊的方法的一个实施例包括获得患者中目标组织的PET / CT成像数据并确定目标组织的质心。该方法还可以包括获得患者的外部运动信号并确定外部运动信号的平均位移。目标组织的质心可以与平均位移相关，并且基于相关性可以重建针对目标组织运动的PET / CT图像。

3. 发明授权

US07858925B2 Calibration method and system for PET scanners 有权
标题翻译： PET扫描仪的校准方法和系统
公开(公告)号：US07858925B2
公开(公告)日：2010-12-28
申请号：US12472285
申请日：2009-05-26
申请人： Paul E. Kinahan , Keith C. Allberg , Robert K. Doot , Catherine M. Lockhart , Wendy McDougald
发明人： Paul E. Kinahan , Keith C. Allberg , Robert K. Doot , Catherine M. Lockhart , Wendy McDougald
IPC分类号： G01D18/00
CPC分类号： G01D18/00 , A61B6/037 , A61B2560/0223 , G21F5/015
摘要： A method, system and kit for calibrating a PET scanner is disclosed. A first aliquot (10) containing a quantity of a radionuclide dispersed in a solid matrix material is provided, wherein the first aliquot is sized and configured to be received for measurement by a conventional dose calibrator. A second aliquot (200) containing a quantity of the radionuclide dispersed in the solid matrix material is sized configured to be scanned in a PET scanner. The radionuclide/matrix materials in the first and second aliquots are obtained from the same batch of material, such that the two quantities have the same radioactivity density, or are obtained from different cross-calibrated batches of material. In a method, the first aliquot is placed in a does calibrator (36) and the radioactivity is measured. The second aliquot is scanned in the PET scanner (190) and the intensity of the image is correlated with the known radioactivity measured by the dose calibrator and used to calibrate the PET scanner.
摘要翻译：公开了一种用于校准PET扫描仪的方法，系统和套件。提供了包含分散在固体基质材料中的一定数量的放射性核素的第一等分试样（10），其中所述第一等分试样的尺寸和构造被接收以供常规剂量校准器测量。包含分散在固体基质材料中的一定数量的放射性核素的第二等分试样（200）的尺寸被配置为在PET扫描器中扫描。第一和第二等分试样中的放射性核素/基体材料是从相同批次的材料获得的，使得两个量具有相同的放射性密度，或者是从不同的交叉校准批次的材料获得的。在一种方法中，将第一等分试样放置在校准器（36）中，并测量放射性。在PET扫描仪（190）中扫描第二等分试样，并且图像的强度与由剂量校准器测量的已知放射性相关并用于校准PET扫描仪。

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