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    • 3. 发明申请
    • Spin trimmer and method of trimming
    • 旋转修剪器和修剪方法
    • US20070089573A1
    • 2007-04-26
    • US11507210
    • 2006-08-21
    • Ralph WilliamsDaniel Lockwood
    • Ralph WilliamsDaniel Lockwood
    • B23B1/00
    • B26D3/166B29C49/04B29C49/06Y10T82/16016Y10T83/04
    • Apparatus is disclosed for trimming scrap material, such as a dome or moil, from a plastic container or other object, which is typically formed with the neck of the container during molding. The apparatus comprises a pair of power driven endless belts, each having an inner reach with the inner reaches of the belts being spaced apart from one another so as to grip a portion of the container (typically the scrap dome or moil to be trimmed) therebetween and so as to move the container along a path. The belts are driven so that the inner reaches of each of the belts move in the same direction so that a container gripped between the belt reaches is conveyed along the work path. One of the belts is driven at a surface speed faster than the surface speed of the other belt so as to rotate the container gripped by the belt reaches about a vertical axis. An elongate blade extends along at least a portion of the work path and is positioned proximate to the work path so as to trim the scrap from the container as the container is conveyed along the work path and as the container is rotated by the belt reaches. A method of trimming such scrap is also disclosed.
    • 公开了用于从塑料容器或其他物体修整诸如圆顶或马尔的废料的装置,其通常在模制期间与容器的颈部一起形成。 该装置包括一对动力驱动的环形带,每个带有内部的距离,带的内部的距离彼此间隔开,以便夹持容器的一部分(通常是待修剪的废穹顶或马蹄) 并且沿着路径移动容器。 驱动皮带使得每个皮带的内部移动沿相同的方向移动,使得夹在皮带到达部之间的容器沿着工作路径传送。 其中一个带以比另一个带的表面速度更快的表面速度被驱动,以便使由皮带夹持的容器旋转到达垂直轴线。 细长刀片沿着工作路径的至少一部分延伸并且被定位成靠近工作路径,以便当容器沿着工作路径被输送时以及当容器被带束带旋转时,从容器中修剪废料。 还公开了一种修整这种废料的方法。
    • 5. 发明申请
    • Double-sleeved electrostatographic roller
    • 双袖电磁辊
    • US20050111889A1
    • 2005-05-26
    • US10965642
    • 2004-10-14
    • Steven CormierDennis GrabbRalph Williams
    • Steven CormierDennis GrabbRalph Williams
    • G03G15/00G03G15/01
    • G03G15/752
    • A double-sleeved roller (DSR) including: a mandrel having a disconnectable end incorporating three termination plates having specified axial profiles; a replaceable inner sleeve member (ISM) mounted on the mandrel; and, a replaceable multilayer outer sleeve member (OSM) including at least one synthetic layer with the OSM surrounding the ISM. The mandrel, adapted to support a non-reinforced ISM, includes the termination plates joined together so as to define two sets of channels for selectively conveying pressurized air to either OSM or ISM for radial expansion thereof. The termination plates have specialized outer shapes, with each termination end plate including a cylindrical portion adjoining a tapered portion. For removal and/or replacement of the OSM or the ISM, a removable support member is moved away from the disconnectable end of the roller while the other end of the roller continues to be supported in cantilever fashion.
    • 一种双套滚子(DSR),包括:具有可分离端的心轴,其具有三个具有特定轴向轮廓的端接板; 安装在心轴上的可更换的内套筒构件(ISM); 以及包括至少一个具有围绕ISM的OSM的合成层的可更换的多层外套筒构件(OSM)。 适于支撑非增强ISM的心轴包括连接在一起的端接板,以便限定两组通道,用于选择性地将加压空气输送到OSM或ISM以进行径向膨胀。 终端板具有专门的外形,每个终端板包括邻接锥形部分的圆柱形部分。 为了拆卸和/或更换OSM或ISM,可移除的支撑构件从辊的可断开的端部移开,而辊的另一端继续以悬臂方式支撑。
    • 7. 发明授权
    • Methods and compositions for treatment of autoimmune diseases
    • 用于治疗自身免疫疾病的方法和组合物
    • US06231856B1
    • 2001-05-15
    • US09164241
    • 1998-09-30
    • Ralph Williams
    • Ralph Williams
    • A61K39395
    • C07K16/42A61K38/00A61K2039/505C07K16/4208Y10S530/866Y10S530/868
    • The subject invention concerns a method for therapeuticaly treating a patient afflicted with autoimmune disorders or disease. The subject method comprises admninistering to a patient an antibody composition that is capable of binding to and inhibiting self-reactive pathogenic anti-bodies present within the patient. Specifically exemplified is a method for treating systemic lupus erythematosis wherein the antibody composition administered to the patient comprises purified anti-DNA anti-idiotypic antibodies. The subject invention further concerns a method for purifying from pooled human gamma globulin preparations anti-idiotype antibodies useful in the present therapeutic method. The present invention further concerns a purified antibody composition useful in the present therapeutic method.
    • 本发明涉及治疗性治疗患有自身免疫性疾病或疾病的患者的方法。 本发明方法包括向患者灌注能够结合并抑制患者内存在的自身反应性病原性抗体的抗体组合物。 具体举例说明了用于治疗系统性红斑狼疮的方法,其中向患者施用的抗体组合物包含纯化的抗DNA抗独特型抗体。 本发明还涉及从本发明治疗方法中有用的合并的人γ球蛋白制剂抗独特型抗体中纯化的方法。 本发明还涉及可用于本治疗方法的纯化抗体组合物。
    • 9. 发明授权
    • Methods and compositions for treatment of autoimmune diseases
    • 用于治疗自身免疫疾病的方法和组合物
    • US06726909B2
    • 2004-04-27
    • US09827117
    • 2001-04-05
    • Ralph Williams
    • Ralph Williams
    • A61K39395
    • C07K16/42A61K38/00A61K2039/505C07K16/4208Y10S530/866Y10S530/868
    • The subject invention concerns a method for therapeutically treating a patient afflicted with autoimmune disorders or disease. The subject method comprises administering to a patient an antibody composition that is capable of binding to and inhibiting self-reactive pathogenic antibodies present within the patient. Specifically exemplified is a method for treating systemic lupus erythematosis wherein the antibody composition administered to the patient comprises purified anti-DNA anti-idiotypic antibodies. The subject invention further concerns a method for purifying from pooled human gamma globulin preparations anti-idiotype antibodies useful in the present therapeutic method. The present invention further concerns a purified antibody composition useful in the present therapeutic method.
    • 本发明涉及用于治疗患有自身免疫性疾病或疾病的患者的方法。 本发明方法包括向患者施用能够结合并抑制存在于患者内的自身反应性病原性抗体的抗体组合物。 具体举例说明了用于治疗系统性红斑狼疮的方法,其中向患者施用的抗体组合物包含纯化的抗DNA抗独特型抗体。 本发明还涉及从本发明治疗方法中有用的合并的人γ球蛋白制剂抗独特型抗体中纯化的方法。 本发明还涉及可用于本治疗方法的纯化抗体组合物。