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    • 5. 发明授权
    • System for updating channel lineup for broadcasting and switched digital broadcasting services
    • 用于更新广播和交换数字广播业务的频道阵容的系统
    • US08566888B2
    • 2013-10-22
    • US11963378
    • 2007-12-21
    • Jiong GongDavid P. Reed
    • Jiong GongDavid P. Reed
    • H04N7/173
    • H04H20/78H04H20/103H04H20/38H04N21/2408H04N21/6118H04N21/631H04N21/64H04N21/6405
    • In a system that is capable of operating in a broadcast mode and a switched mode, it is advantageous to be able to shift program delivery between the two modes. Thus when one video program is being delivered to at least a first customer in a first mode, this program may be delivered to at least a second customer in a second mode that is different from the first mode. In this manner, the video program that is being delivered to first customer will be maintained in the original mode while new requests for this program will be served in a different mode until the delivery of the program to the first customer has been completed. In other words, legacy program delivery is maintained until the program delivery has been completed or otherwise terminated, while delivery of the program in response to new requests for the same program will be delivered in a different mode instead.
    • 在能够以广播模式和切换模式操作的系统中,能够在两种模式之间移动节目传递是有利的。 因此,当以第一模式向至少第一客户传送一个视频节目时,可以以与第一模式不同的第二模式将该节目传送给至少第二客户。 以这种方式,正在交付给第一客户的视频节目将被保持在原始模式,同时将以不同的模式提供对该节目的新请求,直到节目传送给第一客户已经完成。 换句话说,传统的程序传递被维持,直到程序传送已经完成或以其他方式终止,而响应于对相同程序的新请求的程序的递送将以不同的模式被递送。
    • 8. 发明申请
    • Purified Pyrroloquinolinyl-Pyrrolidine-2,5-Dione Compositions And Methods For Preparing And Using Same
    • 纯化的吡咯并喹啉基 - 吡咯烷-2,5-二酮组合物及其制备和使用方法
    • US20110160242A1
    • 2011-06-30
    • US12975644
    • 2010-12-22
    • David P. ReedNeil R. BarnesJohn C. KaneChristopher A. LeeJian-Xie ChenMartin P. Redmon
    • David P. ReedNeil R. BarnesJohn C. KaneChristopher A. LeeJian-Xie ChenMartin P. Redmon
    • A61K31/473C07D471/06A61P35/00
    • C07D471/04C07D471/06
    • The present invention relates to a form 1 and form 2 polymorph of (−)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione. The present invention also relates to (−)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione compounds having a chiral purity greater than 99%, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising these (−)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a composition comprising (−)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione having a chiral purity greater than 99% or a form 1 and form 2 polymorph of (−)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione.
    • 本发明涉及( - ) - 反式-3-(5,6-二氢-4H-吡咯并〔3,2,1-ij〕喹啉-1-基)-4-( -1H-吲哚-3-基)吡咯烷-2,5-二酮。 本发明还涉及( - ) - 反式-3-(5,6-二氢-4H-吡咯并[3,2,1-ij]喹啉-1-基)-4-(1H-吲哚-3-基 )吡咯烷-2,5-二酮化合物及其制备方法。 本发明还涉及包含这些( - ) - 反式-3-(5,6-二氢-4H-吡咯并[3,2,1-ij]喹啉-1-基)-4-(1H-吲哚 -3-基)吡咯烷-2,5-二酮化合物。 本发明提供了通过向有需要的受试者施用治疗有效量的包含( - ) - 反式-3-(5,6-二氢-4H-吡喃并[ 吡咯并[3,2,1-ij]喹啉-1-基)-4-(1H-吲哚-3-基)吡咯烷-2,5-二酮,手性纯度大于99%,形式1和形式2 ( - ) - 反式-3-(5,6-二氢-4H-吡咯并[3,2,1-ij]喹啉-1-基)-4-(1H-吲哚-3-基)吡咯烷-2 ,5-二酮。
    • 10. 发明授权
    • Low attention recording unit for use by vigorously active recorder
    • 低注意记录单元,用于强力录音机使用
    • US06563532B1
    • 2003-05-13
    • US09557169
    • 2000-04-21
    • Henry B. StrubDavid A. BurgessKimberly H. JohnsonJonathan R. CohenDavid P. ReedG. Roberto Aiello
    • Henry B. StrubDavid A. BurgessKimberly H. JohnsonJonathan R. CohenDavid P. ReedG. Roberto Aiello
    • H04N718
    • G11B27/031G11B27/3027G11B2220/216G11B2220/218G11B2220/2562G11B2220/90
    • The invention enables “low attention recording,” i.e., recording that need not appreciably affect interaction of a recorder (i.e., a person in control of a recording unit according to the invention) or others with the environment in which the recording is taking place. The low attention recording enabled by the invention can be particularly advantageously employed in “social recording,” i.e., recording in which multiple participants in an event are recording the event. As described in more detail below, advantageous aspects of the invention can be provided by a small, lightweight, wearable recording unit. In particular, a recording unit according to the invention is particularly adapted to enable use of the recording unit to record an event during which the recorder engages in vigorous physical activity (e.g., an athletic activity, such as hiking, snow skiing or ping pong). The recording unit is constructed with a particular emphasis on the wearability characteristics of the recording unit, in order to facilitate freedom of movement by the recorder and minimize distraction to, or encumbrance of, the recorder's participation in the activity.
    • 本发明使得“低注意记录”即不需要明显地影响记录器(即,根据本发明的记录单元的控制人员)或其他与记录发生的环境的相互作用的记录。 通过本发明实现的低注意记录可以特别有利地用于“社交记录”,即记录事件中的多个参与者记录事件的记录。 如下面更详细地描述的,本发明的有利方面可以由小型,重量轻,耐磨的记录单元提供。 特别地,根据本发明的记录单元特别适于使记录单元能够记录记录器进行剧烈的身体活动(例如,诸如远足,滑雪或乒乓球等运动活动)的事件, 。 记录单元的构造特别强调记录单元的耐磨特性,以便于记录器的移动自由度,并最大限度地减少记录器参与活动的注意力或产生负担。