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    • 2. 发明申请
    • SMALL ANIMAL RESTRAINING DEVICE WITH NON-TRAUMATIC ANIMAL LOADING DEVICE
    • 具有非交叉动物装载装置的小动物限制装置
    • US20080168948A1
    • 2008-07-17
    • US12013410
    • 2008-01-11
    • Patrick W. TruittBernard F. HeteEric W. Starr
    • Patrick W. TruittBernard F. HeteEric W. Starr
    • A01K29/00A01K1/06A61D3/00
    • A01K1/0613A61D3/00
    • A small animal restraining tube comprises a tube configured to receive a small animal therein; a nosecone within the tube and coupled thereto and configured to abut the animal within the tube to confine the animal on one side of the tube; an endplate coupled to the tube and configured to confine a body portion of the animal on a side opposite the nosecone, whereby the body of the animal is confined within the tube between the nosecone and the endplate, the endplate including an opening there through configured to receive a tail of the animal when the animal is confined within the tube; and a tubular loader mechanism selectively coupled to the tube, wherein the loader mechanism is configured to selectively receive the animal therein and configured to transfer the animal to the retraining tube.
    • 小动物限制管包括构造成在其中容纳小动物的管; 管内并且与管连接并配置成邻接管内的动物以将动物限制在管的一侧上; 端板,其耦合到所述管并且被配置为将所述动物的身体部分限制在与所述鼻子相对的一侧上,由此所述动物的身体被限制在所述管中,所述鼻甲和所述端板之间,所述端板包括通过所述开口配置成 当动物被限制在管内时,接收动物的尾巴; 以及选择性地联接到所述管的管状装载机构,其中所述装载机构构造成选择性地接收所述动物并且构造成将所述动物转移到所述再培训管。
    • 7. 发明申请
    • Small Bore Magnetic Resonance Imaging Photoplethysmographic Sensor
    • 小孔磁共振成像光电体积描记传感器
    • US20100113902A1
    • 2010-05-06
    • US12606180
    • 2009-10-26
    • Bernard F. HeteEric W. StarrChris Zawada
    • Bernard F. HeteEric W. StarrChris Zawada
    • A61B5/1455A61B5/055
    • G01R33/4808A61B5/055A61B5/14552A61B2503/40
    • An efficient, effective, MRI compatible small bore MRI noninvasive photoplethysmographic sensor for animals such as small rodents, namely rats and mice. The photoplethysmographic sensor for animals comprising: a non-magnetic sensor coupling attachable to an animal; fiber optic cable coupled to the sensor coupling and configured to deliver a signal to and receive a signal from the animal tissue adjacent the sensor coupling; an opto-electical converter coupled to the fiber optic cable, the converter including a receiver coupled the fiber optic cable portion configured to receive a signal from the animal tissue and including an emitter coupled to the fiber optic portion configured to deliver a signal to the animal tissue; an electronic coupling extending from the opto-electric converter and configured to be coupled to the emitter and the receiver, wherein the electronic coupling is configured to extend outside of the MRI chamber; and a processor coupled to the electronic coupling.
    • 一种高效,有效的MRI兼容小型MRI无创光电体积描记传感器,用于小型啮齿动物,即大鼠和小鼠等动物。 用于动物的光电容积传感器包括:可附接到动物的非磁性传感器耦合器; 光纤电缆耦合到传感器耦合并被配置成将信号传递到邻近传感器耦合器的动物组织并从其接收信号; 耦合到所述光纤电缆的光电转换器,所述转换器包括耦合所述光纤电缆部分的接收器,所述光纤电缆部分被配置为接收来自所述动物组织的信号,并且包括耦合到所述光纤部分的发射器,所述发射器被配置为向所述动物传递信号 组织; 电子耦合器,其从所述光电转换器延伸并且被配置为耦合到所述发射器和所述接收器,其中所述电子耦合器被配置为延伸到所述MRI室外; 以及耦合到电子耦合器的处理器。
    • 9. 发明申请
    • BLOOD PRESSURE MONITOR AND PULSE OXIMETER SYSTEM FOR ANIMAL RESEARCH
    • 用于动物研究的血压监视器和脉冲输出系统
    • US20120004517A1
    • 2012-01-05
    • US12980324
    • 2010-12-28
    • Eric W. StarrBernard F. Hete
    • Eric W. StarrBernard F. Hete
    • A61B5/02A61B5/1455A61B5/022
    • A61B5/02255A61B5/14552A61B2503/40
    • An integrated blood pressure monitor and pulse oximeter system includes a blood flow occlusion member configured to selectively occlude blood flow through an appendage of the animal (e.g., the neck or tail); a sensor coupled to the blood flow occlusion member detecting a degree of operation thereof; Light sources coupled to the tail closer to the distal end of the tail than the tail blood flow occlusion member, and selectively directing light of two different wavelengths into the appendage; a light receiver coupled to the appendage and selectively receiving a signal associated with light directed into the appendage from the light sources; and a controller configured to selectively determine blood pressure parameters from the data and pulse oximeter parameters from the data.
    • 综合血压监测器和脉搏血氧计系统包括血液阻塞构件,其构造成选择性地阻塞通过动物的附肢(例如颈部或尾部)的血流; 耦合到所述血流阻塞构件的传感器,其检测其操作程度; 耦合到尾部的光源比尾部血流阻塞构件更靠近尾部远端,并且将两种不同波长的光选择性地引导到附属物中; 耦合到附件的光接收器并且选择性地接收与从光源引导到附属物中的光相关联的信号; 以及控制器,被配置为从数据中选择性地从数据和脉搏血氧计参数确定血压参数。
    • 10. 发明申请
    • Saddle Faced Small Animal Sensor Clip
    • 马鞍形小动物传感器夹
    • US20110137185A1
    • 2011-06-09
    • US12785421
    • 2010-05-21
    • Bernard F. HeteEric W. Starr
    • Bernard F. HeteEric W. Starr
    • A61B5/02A61B5/00
    • A61B5/14552A61B5/6826A61B2503/40
    • A noninvasive photoplethysmographic sensor platform for small animals provides a spring biased sensor clip, wherein at least one side of the sensor clip is provided with a saddle faced clip face member. The saddle shape of the clip face member may have a hinge end, toward the hinge of the clip, which is longer in the longitudinal direction of the clip and shorter in depth than the distal end. The shorter distal end side (measured longitudinally) of this saddle shape facilitates the ability to align the transmitted and received light with the bone, while the overall saddle shape of the facing provides a physical grip to capture enough tissue to prevent the clip from relocating over time while it is attached to the limb. The shorter hinge end side (depth-wise) also allows the clip to close when it is fully assembled. The edges of the saddle shaped clip are preferably rounded off to prevent the contusions of the tissue that may result from long-term contact. This saddle faced feature works well on only one side of the clip.
    • 用于小动物的非侵入式光电容积传感器平台提供弹簧偏置传感器夹,其中传感器夹的至少一侧设置有鞍形面夹具构件。 夹面构件的鞍座形状可以具有朝向夹子的铰链的铰链端,其在夹子的纵向方向上较长并且比远端更深。 这种马鞍形状的较短的远端侧(纵向测量)有助于将透射和接收的光与骨骼对准的能力,而面部的整体鞍座形状提供物理抓地力以捕获足够的组织以防止夹子重新定位在 时间,而它附加到肢体。 较短的铰链端侧(深度方向)也允许夹子完全组装后关闭。 鞍状夹子的边缘优选地倒圆,以防止长期接触可能引起的组织挫伤。 这个马鞍面对的功能只能在剪辑的一侧工作。