专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050106066A1 Microfluidic devices for fluid manipulation and analysis 有权
标题翻译：用于流体操纵和分析的微流体装置
公开(公告)号：US20050106066A1
公开(公告)日：2005-05-19
申请号：US10870717
申请日：2004-06-17
申请人： Patrick Saltsman , Mingchao Shen , Jeffrey Houkal , Christy Lancaster , C. Battrell , Bernhard Weigl
发明人： Patrick Saltsman , Mingchao Shen , Jeffrey Houkal , Christy Lancaster , C. Battrell , Bernhard Weigl
IPC分类号： B01F5/04 , B01F5/06 , B01F13/00 , B01L3/00 , F04B43/04 , F16K15/18
CPC分类号： B01L3/50273 , B01F5/0473 , B01F5/0646 , B01F5/0647 , B01F13/0059 , B01L3/5027 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L3/502753 , B01L2200/0621 , B01L2200/10 , B01L2300/0636 , B01L2300/0681 , B01L2300/0861 , B01L2300/0867 , B01L2300/1805 , B01L2400/0406 , B01L2400/0481 , B01L2400/0487 , B01L2400/049 , B01L2400/0605 , B01L2400/0633 , F04B43/043 , G01N33/5304 , G01N33/80
摘要： The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.
摘要翻译：本发明涉及用于操纵和分析流体样品的微流体装置和方法。所公开的微流体装置利用多个微流体通道，入口，阀，过滤器，泵，液体屏障和以各种配置布置的其它元件来操纵流体样品的流动，以制备用于分析的样品。

2. 发明申请

US20050013732A1 Method and system for microfluidic manipulation, amplification and analysis of fluids, for example, bacteria assays and antiglobulin testing 有权
标题翻译：用于流体微流控操作，扩增和分析的方法和系统，例如细菌测定和抗球蛋白测试
公开(公告)号：US20050013732A1
公开(公告)日：2005-01-20
申请号：US10762586
申请日：2004-01-21
申请人： C. Battrell , Mingchao Shen , Bernhard Weigl , Jeffrey Houkal , Christy Lancaster , Wayne Breidford
发明人： C. Battrell , Mingchao Shen , Bernhard Weigl , Jeffrey Houkal , Christy Lancaster , Wayne Breidford
IPC分类号： B01F5/04 , B01F5/06 , B01F13/00 , B01L3/00 , F04B43/04 , C12Q1/68
CPC分类号： F04B43/043 , B01F5/0473 , B01F5/0646 , B01F5/0647 , B01F13/0059 , B01L3/5027 , B01L3/502707 , B01L3/502715 , B01L3/502753 , B01L7/52 , B01L2200/10 , B01L2300/0636 , B01L2300/0681 , B01L2300/0816 , B01L2300/0861 , B01L2300/0867 , B01L2300/1805 , B01L2400/0487 , B01L2400/0633 , C12Q1/686 , Y10T436/107497 , Y10T436/25 , Y10T436/2525 , Y10T436/25375 , C12Q2565/625 , C12Q2565/629
摘要： A microfluidic system for isolation and amplification of DNA or RNA from aqueous solutions and detection of the DNA or RNA on a lateral flow detection strip, including a disposable microfluidic card for use in analysis of bacteria in platelets and an analysis of sexually transmitted diseases (STD) in urine. The card will include an embedded membrane that filters out cells and cellular debris. Any biological debris on the membrane will be lysed and the DNA or RNA amplified via PCR amplification protocol, including appropriate reagents and thermal cycling conditions. The amplified DNA or RNA are transferred to a lateral flow detection strip for a visual diagnostic read out. An alternate embodiment includes a microfluidic card for use in typing antiglobulin assays.
摘要翻译：一种用于从水溶液中分离和扩增DNA或RNA的微流体系统，并检测侧流检测条上的DNA或RNA，包括用于血小板中细菌分析的一次性微流控卡和性传播疾病分析（STD ）在尿液。该卡将包括一个过滤掉细胞和细胞碎片的嵌入膜。膜上的任何生物碎片将被裂解，并通过PCR扩增方案扩增DNA或RNA，包括适当的试剂和热循环条件。将扩增的DNA或RNA转移到侧向流动检测条中以进行视觉诊断读出。替代实施方案包括用于分选抗球蛋白测定的微流控卡。

3. 发明申请

US20060246575A1 Microfluidic rare cell detection device 审中-公开
标题翻译：微流体稀有细胞检测装置
公开(公告)号：US20060246575A1
公开(公告)日：2006-11-02
申请号：US11331587
申请日：2006-01-13
申请人： Christy Lancaster , C. Battrell , Jason Capodanno , John Gerdes , Mark Kokoris , Melud Nabavi , Stephen Mordue , Robert McRuer , John Clemmens , Wayne Breidford
发明人： Christy Lancaster , C. Battrell , Jason Capodanno , John Gerdes , Mark Kokoris , Melud Nabavi , Stephen Mordue , Robert McRuer , John Clemmens , Wayne Breidford
IPC分类号： C12M1/34
CPC分类号： F16K99/0001 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L3/502761 , B01L3/502776 , B01L7/52 , B01L2200/0636 , B01L2200/0647 , B01L2200/10 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/0874 , B01L2300/0887 , B01L2400/0487 , B01L2400/0633 , F16K99/0007 , F16K99/0034 , F16K99/0046 , F16K2099/008 , F16K2099/0084 , G01N1/34 , G01N15/1459 , G01N15/1463 , G01N15/1484 , G01N2015/0069 , G01N2015/1409 , G01N2015/1486 , G01N2015/149
摘要： The present invention relates to microfluidic devices and methods for detecting rare cells. The disclosed microfluidic devices and methods integrate and automate sample preparation, cell labeling, cell sorting and enrichment, and DNA/RNA analysis of sorted cells.
摘要翻译：本发明涉及用于检测稀有细胞的微流体装置和方法。所公开的微流体装置和方法将样品制备，细胞标记，细胞分选和富集以及分选细胞的DNA / RNA分析整合并自动化。

4. 发明申请

US20070178529A1 ELECTROMAGNETICALLY ACTUATED VALVES FOR USE IN MICROFLUIDIC STRUCTURES 审中-公开
标题翻译：用于微流体结构的电磁致动阀
公开(公告)号：US20070178529A1
公开(公告)日：2007-08-02
申请号：US11622733
申请日：2007-01-12
申请人： Wayne Breidford , C. Battrell
发明人： Wayne Breidford , C. Battrell
IPC分类号： G01N33/53
CPC分类号： F16K15/185 , B01F11/04 , B01F13/0059 , B01F13/0827 , B01L3/502738 , B01L3/502761 , B01L2200/0647 , B01L2200/143 , B01L2300/0816 , B01L2300/0864 , B01L2300/0874 , B01L2300/0887 , B01L2400/0622 , B01L2400/0633 , B01L2400/0638 , F16K15/16 , F16K31/06 , F16K99/0001 , F16K99/0007 , F16K99/0046 , F16K2099/0084
摘要： Disclosed are micron-sized, electromagnetically actuated tongue valves, which find application in microfluidic devices and apparatuses. The present invention further relates to methods for manipulating fluid flow in a microfluidic assay system and for sorting and capturing target particles in fluid suspensions.
摘要翻译：公开了微米尺寸的电磁致动舌阀，其可应用于微流体装置和装置中。本发明还涉及用于操纵微流体测定系统中的流体流动并用于在流体悬浮液中分选和捕获目标颗粒的方法。

5. 发明申请

US20070183935A1 MICROFLUIDIC MIXING AND ANALYTICAL APPARATUS 有权
标题翻译：微流控混合和分析装置
公开(公告)号：US20070183935A1
公开(公告)日：2007-08-09
申请号：US11562611
申请日：2006-11-22
申请人： John Clemmens , C. Battrell , John Gerdes , Denise Hoekstra
发明人： John Clemmens , C. Battrell , John Gerdes , Denise Hoekstra
IPC分类号： B01L3/02
CPC分类号： B01F13/0059 , B01F11/0071 , B01L3/502723 , B01L3/50273 , B01L3/502738 , B01L3/502761 , B01L2300/0816 , B01L2400/0481 , B01L2400/0655 , C12M23/16 , C12M23/42 , C12M25/16 , C12M29/10 , G01N2035/00544 , G01N2035/00564
摘要： Disclosed herein is a device comprising a pair of bellows pumps configured for efficient mixing at a microfluidic scale. By moving a fluid sample and particles in suspension through an aperture between the paired bellows pump mixing chambers, molecular collisions leading to binding between the particles and ligands in the sample are enhanced. Such devices provide an alternative for mixing that does not use a vent and can be used with a variety of particles in suspension such as magnetic beads to capture or purify useful cells and molecules.
摘要翻译：本文公开了一种包括一对波纹管泵的装置，其配置为在微流控尺度上有效地混合。通过将流体样品和悬浮液中的颗粒通过成对的波纹管泵混合室之间的孔移动，导致样品中颗粒和配体之间的结合的分子碰撞得到增强。这样的装置提供了不使用排气口的混合的替代方案，并且可以与诸如磁珠的悬浮液中的各种颗粒一起使用以捕获或净化有用的细胞和分子。

6. 发明申请

US20070042427A1 Microfluidic laminar flow detection strip 审中-公开
标题翻译：微流体层流检测条
公开(公告)号：US20070042427A1
公开(公告)日：2007-02-22
申请号：US11416791
申请日：2006-05-03
申请人： John Gerdes , C. Battrell , Denise Hoekstra , John Clemmens , Stephen Mordue
发明人： John Gerdes , C. Battrell , Denise Hoekstra , John Clemmens , Stephen Mordue
IPC分类号： G01N33/53 , C12M3/00
CPC分类号： G01N33/54386 , G01N33/54366
摘要： The present invention relates to microfluidic laminar flow detection strip devices and methods for using and making the same. The disclosed devices comprise: a first inlet; a microfluidic channel having a first end and a second end, wherein the first end is fluidly connected to the first inlet; a bellows pump fluidly connected to the second end of the microfluidic channel, wherein the bellows pump comprises an absorbent material disposed therein; a dried reagent zone within the microfluidic channel, wherein the dried reagent zone comprises a first reagent and a control reagent printed thereon, the first reagent comprising a first detection antibody conjugated to a dyed substrate bead or functionalized for colorimetric development, and the control reagent comprising a control detection antibody conjugated to a dyed substrate bead or functionalized for calorimetric development; a first bound antibody zone within the microfluidic channel, wherein the first bound antibody zone comprises a first bound antibody printed thereon; and a control zone within the microfluidic channel, wherein the control zone comprises a control bound antibody printed thereon.
摘要翻译：本发明涉及微流体层流检测带装置及其制造方法。所公开的装置包括：第一入口; 微流体通道，其具有第一端和第二端，其中所述第一端流体连接到所述第一入口; 流体连接到微流体通道的第二端的波纹管泵，其中波纹管泵包括设置在其中的吸收材料; 微流体通道内的干燥试剂区，其中干燥的试剂区包含印刷在其上的第一试剂和对照试剂，第一试剂包含与染色的底物珠缀合或用于比色显影官能化的第一检测抗体，并且所述对照试剂包含与染色的基质珠缀合的控制检测抗体或用于量热显影功能化的对照检测抗体; 所述微流体通道内的第一结合抗体区，其中所述第一结合抗体区包含印刷在其上的第一结合抗体; 和微流体通道内的对照区，其中控制区包含印刷在其上的对照结合抗体。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式