专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US6060644A Isolation and use of cuticular lipid genes 失效
标题翻译：分离和使用角质脂质基因
公开(公告)号：US6060644A
公开(公告)日：2000-05-09
申请号：US581148
申请日：1995-12-29
申请人： Patrick S. Schnable , Donald S. Robertson , Joel D. Hansen , Basil J. Nikolau , Xiaojie Xu , Yiji Xia
发明人： Patrick S. Schnable , Donald S. Robertson , Joel D. Hansen , Basil J. Nikolau , Xiaojie Xu , Yiji Xia
IPC分类号： C07K14/415 , C12N9/00 , C12N9/10 , C12N15/82 , A01H5/00 , C12N5/04
CPC分类号： C07K14/415 , C12N15/8247 , C12N15/8279 , C12N9/00 , C12N9/1029
摘要： The present invention relates to cuticular lipid genes, their gene products, and methods of use thereof, for the generation of new plant varieties having novel environmental, disease and pest resistance. In particular, certain isolated or enriched nucleic acids specifying cuticular lipid genes, or portions thereof, are disclosed.
摘要翻译：本发明涉及角质层脂质基因，其基因产物及其使用方法，用于产生具有新型环境，疾病和害虫抗性的新植物品种。特别地，公开了指定角质层脂质基因的某些分离或富集的核酸或其部分。

2. 发明授权

US06764851B2 Materials and methods for the alteration of enzyme and acetyl CoA levels in plants 失效
标题翻译：用于改变植物中酶和乙酰CoA水平的材料和方法
公开(公告)号：US06764851B2
公开(公告)日：2004-07-20
申请号：US09344882
申请日：1999-06-25
申请人： Basil J. Nikolau , Eve S. Wurtele , David J. Oliver , Robert Behal , Patrick S. Schnable , Jinshan Ke , Jerry L. Johnson , Carolyn C. Allred , Beth Fatland , Isabelle Lutziger , Tsui-Jung Wen
发明人： Basil J. Nikolau , Eve S. Wurtele , David J. Oliver , Robert Behal , Patrick S. Schnable , Jinshan Ke , Jerry L. Johnson , Carolyn C. Allred , Beth Fatland , Isabelle Lutziger , Tsui-Jung Wen
IPC分类号： C12N1574
CPC分类号： C12N15/1137 , C12N9/0008 , C12N9/0051 , C12N9/1029 , C12N9/16 , C12N9/88 , C12N9/93 , C12N15/8243
摘要： The present invention provides nucleic acid and amino acid sequences of acetyl CoA synthetase (ACS), plastidic pyruvate dehydrogenase (pPDH), ATP citrate lyase (ACL), Arabidopsis pyruvate decarboxylase (PDC), and Arabidopsis aldehyde dehydrogenase (ALDH), specifically ALDH-2 and ALDH-4. The present invention also provides a recombinant vector comprising a nucleic acid sequence encoding one of the aforementioned enzymes, an antisense sequence thereto or a ribozyme therefor, a cell transformed with such a vector, antibodies to the enzymes, a plant cell, a plant tissue, a plant organ or a plant in which the level of an enzyme has been altered, and a method of producing such a plant cell, plant tissue, plant organ or plant. Desirably, alteration of the level of enzyme results in an alteration of the level of acetyl CoA in the plant cell, plant tissue, plant organ or plant. In addition, the present invention provides a recombinant vector comprising an antisense sequence of a nucleic acid sequence encoding pyruvate decarboxylase (PDC), the E1&agr;subunit of pPDH, the E1&bgr;subunit of pPDH, the E2 subunit of pPDH, mitochondrial pyurvate dehydrogenase (mtPDH) or aldehyde dehydrogenase (ALDH) or a ribozyme that can cleave an RNA molecule encoding PDC, E1&agr;pPDH, E1&bgr;pPDH, E2 pPDH, mtPDH or ALDH.
摘要翻译：本发明提供乙酰辅酶A合成酶（ACS），质体丙酮酸脱氢酶（pPDH），ATP柠檬酸裂解酶（ACL），拟南芥丙酮酸脱羧酶（PDC）和拟南芥醛脱氢酶（ALDH），特别是ALDH- 2和ALDH-4。本发明还提供了一种重组载体，其包含编码上述酶之一的核酸序列，其上的反义序列或其核酶，用该载体转化的细胞，对酶的抗体，植物细胞，植物组织，其中酶的水平已被改变的植物器官或植物，以及生产这种植物细胞，植物组织，植物器官或植物的方法。理想地，酶水平的改变导致植物细胞，植物组织，植物器官或植物中乙酰CoA水平的改变。此外，本发明提供了包含编码丙酮酸脱羧酶（PDC）的核酸序列，pPDH的E1a亚单位，pPDH的E1betubunit，pPDH的E2亚基，线粒体高磷酸脱氢酶（mtPDH）或醛的反义序列的重组载体脱氢酶（ALDH）或可以切割编码PDC，E1alphapPDH，E1betapPDH，E2pPDH，mtPDH或ALDH的RNA分子的核酶。

3. 发明授权

US07524678B2 Materials and methods for the alteration of enzyme and acetyl CoA levels in plants 失效
标题翻译：用于改变植物中酶和乙酰CoA水平的材料和方法
公开(公告)号：US07524678B2
公开(公告)日：2009-04-28
申请号：US11167856
申请日：2005-06-27
申请人： Basil J. Nikolau , Eve S. Wurtele , David J. Oliver , Patrick S. Schnable , Tsui-Jung Wen
发明人： Basil J. Nikolau , Eve S. Wurtele , David J. Oliver , Patrick S. Schnable , Tsui-Jung Wen
IPC分类号： C12N5/10
CPC分类号： C12N15/1137 , C12N9/0008 , C12N9/0051 , C12N9/1029 , C12N9/16 , C12N9/88 , C12N9/93 , C12N15/8243
摘要： The present invention provides nucleic acid and amino acid sequences of acetyl CoA synthetase (ACS), plastidic pyruvate dehydrogenase (pPDH), ATP citrate lyase (ACL), Arabidopsis pyruvate decarboxylase (PDC), and Arabidopsis aldehyde dehydrogenase (ALDH), specifically ALDH-2 and ALDH-4. The present invention also provides a recombinant vector comprising a nucleic acid sequence encoding one of the aforementioned enzymes, an antisense sequence thereto or a ribozyme therefor, a cell transformed with such a vector, antibodies to the enzymes, a plant cell, a plant tissue, a plant organ or a plant in which the level of an enzyme has been altered, and a method of producing such a plant cell, plant tissue, plant organ or plant. Desirably, alteration of the level of enzyme results in an alteration of the level of acetyl CoA in the plant cell, plant tissue, plant organ or plant. In addition, the present invention provides a recombinant vector comprising an antisense sequence of a nucleic acid sequence encoding pyruvate decarboxylase (PDC), the E1α subunit of pPDH, the E1β subunit of pPDH, the E2 subunit of pPDH, mitochondrial pyruvate dehydrogenase (mtPDH) or aldehyde dehydrogenase (ALDH) or a ribozyme that can cleave an RNA molecule encoding PDC, E1α pPDH, E1β pPDH, E2 pPDH, mtPDH or ALDH.
摘要翻译：本发明提供乙酰辅酶A合成酶（ACS），质体丙酮酸脱氢酶（pPDH），ATP柠檬酸裂合酶（ACL），拟南芥丙酮酸脱羧酶（PDC）和拟南芥醛脱氢酶（ALDH），特别是ALDH- 2和ALDH-4。本发明还提供了一种重组载体，其包含编码上述酶之一的核酸序列，其上的反义序列或其核酶，用该载体转化的细胞，对酶的抗体，植物细胞，植物组织，其中酶的水平已被改变的植物器官或植物，以及生产这种植物细胞，植物组织，植物器官或植物的方法。理想地，酶水平的改变导致植物细胞，植物组织，植物器官或植物中乙酰CoA水平的改变。此外，本发明提供了包含编码丙酮酸脱羧酶（PDC），pPDH的E1alpha亚基，pPDH的E1beta亚基，pPDH的E2亚基，线粒体丙酮酸脱氢酶（mtPDH）的核酸序列的反义序列的重组载体，或醛脱氢酶（ALDH）或可以切割编码PDC，E1alpha pPDH，E1beta pPDH，E2pPDH，mtPDH或ALDH的RNA分子的核酶。

4. 发明授权

US06942994B2 Materials and methods for the alteration of enzyme and acetyl CoA levels in plants 失效
标题翻译：用于改变植物中酶和乙酰CoA水平的材料和方法
公开(公告)号：US06942994B2
公开(公告)日：2005-09-13
申请号：US10293865
申请日：2002-11-13
申请人： Basil J. Nikolau , Eve S. Wurtele , David J. Oliver , Robert Behal , Patrick S. Schnable , Jinshan Ke , Jerry L. Johnson , Carolyn C. Allred , Beth Fatland , Isabelle Lutziger , Tsui-Jung Wen
发明人： Basil J. Nikolau , Eve S. Wurtele , David J. Oliver , Robert Behal , Patrick S. Schnable , Jinshan Ke , Jerry L. Johnson , Carolyn C. Allred , Beth Fatland , Isabelle Lutziger , Tsui-Jung Wen
IPC分类号： A01H1/00 , C12N5/04 , C12N9/00 , C12N9/02 , C12N9/10 , C12N9/16 , C12N9/88 , C12N15/113 , C12N15/82 , C12N15/09 , A01H5/00 , C12N5/10
CPC分类号： C12N15/1137 , C12N9/0008 , C12N9/0051 , C12N9/1029 , C12N9/16 , C12N9/88 , C12N9/93 , C12N15/8243
摘要： The present invention provides nucleic acid and amino acid sequences of acetyl CoA synthetase (ACS), plastidic pyruvate dehydrogenase (pPDH), ATP citrate lyase (ACL), Arabidopsis pyruvate decarboxylase (PDC), and Arabidopsis aldehyde dehydrogenase (ALDH), specifically ALDH-2 and ALDH-4. The present invention also provides a recombinant vector comprising a nucleic acid sequence encoding one of the aforementioned enzymes, an antisense sequence thereto or a ribozyme therefor, a cell transformed with such a vector, antibodies to the enzymes, a plant cell, a plant tissue, a plant organ or a plant in which the level of an enzyme has been altered, and a method of producing such a plant cell, plant tissue, plant organ or plant. Desirably, alteration of the level of enzyme results in an alteration of the level of acetyl CoA in the plant cell, plant tissue, plant organ or plant. In addition, the present invention provides a recombinant vector comprising an antisense sequence of a nucleic acid sequence encoding pyruvate decarboxylase (PDC), the E1α subunit of pPDH, the E1β subunit of pPDH, the E2 subunit of pPDH, mitochondrial pyruvate dehydrogenase (mtPDH) or aldehyde dehydrogenase (ALDH) or a ribozyme that can cleave an RNA molecule encoding PDC, E1α pPDH, E1β pPDH, E2 pPDH, mtPDH or ALDH.
摘要翻译：本发明提供乙酰辅酶A合成酶（ACS），质体丙酮酸脱氢酶（pPDH），ATP柠檬酸裂解酶（ACL），拟南芥丙酮酸脱羧酶（PDC）和拟南芥醛脱氢酶（ALDH），特别是ALDH- 2和ALDH-4。本发明还提供了一种重组载体，其包含编码上述酶之一的核酸序列，其上的反义序列或其核酶，用该载体转化的细胞，对酶的抗体，植物细胞，植物组织，其中酶的水平已被改变的植物器官或植物，以及生产这种植物细胞，植物组织，植物器官或植物的方法。理想地，酶水平的改变导致植物细胞，植物组织，植物器官或植物中乙酰CoA水平的改变。此外，本发明提供了包含编码丙酮酸脱羧酶（PDC），pPDH的E1alpha亚基，pPDH的E1beta亚基，pPDH的E2亚基，线粒体丙酮酸脱氢酶（mtPDH）的核酸序列的反义序列的重组载体，或醛脱氢酶（ALDH）或可切割编码PDC，E1alpha pPDH，E1beta pPDH，E2pPDH，mtPDH或ALDH的RNA分子的核酶。

5. 发明授权

US08951762B2 Materials and methods for using an acyl—acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis 有权
标题翻译：在脂肪酸合成中使用酰基酰基载体蛋白硫酯酶及其突变体和嵌合体的材料和方法
公开(公告)号：US08951762B2
公开(公告)日：2015-02-10
申请号：US13558323
申请日：2012-07-25
申请人： Basil J. Nikolau , Marna Yandeau-Nelson , Fuyuan Jing
发明人： Basil J. Nikolau , Marna Yandeau-Nelson , Fuyuan Jing
IPC分类号： C12P7/64 , C12N9/16 , C12N1/20 , C12N1/00 , C12N1/12 , C07H21/04
CPC分类号： C12N9/16 , C07K2319/00 , C12P7/6409 , C12Y301/02014
摘要： A method of increasing production of fatty acids comprising introducing into a host cell or organism and expressing therein an acyl-acyl carrier protein (ACP) thioesterase (TE) from Bryantella formatexigens or a mutant thereof; a method of making a mutant B. formatexigens acyl-ACP TE; a method of making a chimeric Cuphea viscosissima acyl-ACP TE; a nucleic acid encoding a mutant acyl-ACP TE or a chimeric C. viscosissima acyl-ACP TE; a host cell or organism comprising the nucleic acid; a mutant acyl-ACP TE or chimeric C. viscosissima acyl-ACP TE; a method of altering the specificity of a plant acyl-ACP TE; and a method of altering the level of activity of a plant acyl-ACP TE.
摘要翻译：一种增加脂肪酸生产的方法，其包括向宿主细胞或生物体中引入并在其中表达来自甲酸杆菌或其突变体的酰基酰基载体蛋白（ACP）硫酯酶（TE）; 制备突变型甲酸重组体酰基-ACP TE的方法; 制备嵌合的Cuphea viscosissima酰基-ACP TE的方法; 编码突变型酰基-ACP TE或嵌合C粘稠体酰基-ACP TE的核酸; 包含该核酸的宿主细胞或生物体; 突变的酰基-ACP TE或嵌合的C.粘性酰基-ACP TE; 改变植物酰基-ACP TE的特异性的方法; 以及改变植物酰基-ACP TE的活性水平的方法。

6. 发明申请

US20130029387A1 MATERIALS AND METHODS FOR USING AN ACYL-ACYL CARRIER PROTEIN THIOESTERASE AND MUTANTS AND CHIMERAS THEREOF IN FATTY ACID SYNTHESIS 有权
公开(公告)号：US20130029387A1
公开(公告)日：2013-01-31
申请号：US13558323
申请日：2012-07-25
申请人： Basil J. Nikolau , Marna Yandeau-Nelson , Fuyuan Jing
发明人： Basil J. Nikolau , Marna Yandeau-Nelson , Fuyuan Jing
IPC分类号： C12N9/16 , C12N1/21 , C07H21/04 , C12N1/19 , C12N1/13 , C12P7/64 , C12N1/15
CPC分类号： C12N9/16 , C07K2319/00 , C12P7/6409 , C12Y301/02014
摘要： A method of increasing production of fatty acids comprising introducing into a host cell or organism and expressing therein an acyl-acyl carrier protein (ACP) thioesterase (TE) from Bryantella formatexigens or a mutant thereof; a method of making a mutant B. formatexigens acyl-ACP TE; a method of making a chimeric Cuphea viscosissima acyl-ACP TE; a nucleic acid encoding a mutant acyl-ACP TE or a chimeric C. viscosissima acyl-ACP TE; a host cell or organism comprising the nucleic acid; a mutant acyl-ACP TE or chimeric C. viscosissima acyl-ACP TE; a method of altering the specificity of a plant acyl-ACP TE; and a method of altering the level of activity of a plant acyl-ACP TE.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式