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1. 发明授权

US5165935A Cosmetic or dermatological composition, containing kola extracts and method for treatment of cellulitis 失效
标题翻译：化妆品或皮肤病学组合物，含有罗拉提取物和治疗蜂窝组织炎的方法
公开(公告)号：US5165935A
公开(公告)日：1992-11-24
申请号：US759827
申请日：1991-09-13
申请人： Patrice Andre , Jocelyne Dominice , Pierre Perrier , Gerard Redziniak
发明人： Patrice Andre , Jocelyne Dominice , Pierre Perrier , Gerard Redziniak
IPC分类号： A61K8/96 , A61K8/00 , A61K8/11 , A61K8/14 , A61K8/97 , A61K9/127 , A61K36/00 , A61K36/18 , A61K36/185 , A61K36/48 , A61Q19/00 , A61Q19/06
CPC分类号： A61Q19/06 , A61K36/185 , A61K36/48 , A61K8/14 , A61K8/97 , A61K9/127 , Y10S514/86
摘要： A cosmetic or dermatological composition comprising an extract of kola seeds substantially free of methylxanthine. Other embodiments include a composition comprising liposomes or hydrated lipidic lamellar phases containing an extract of kola seeds having a methylxanthine content or containing an extract of kola seeds substantially free of methylxanthine. Methods for treating cellulitis deposits present on body parts by application of the compositions of the present invention are also disclosed.
摘要翻译：一种化妆品或皮肤病学组合物，其包含基本上不含甲基黄嘌呤的科拉拉种子提取物。其它实施方案包括包含脂质体或水合脂质层状结构的组合物，其含有具有甲基黄嘌呤含量的科拉种子提取物或含有基本上不含甲基黄嘌呤的科拉拉种子提取物。还公开了通过应用本发明的组合物治疗存在于身体部位的蜂窝织炎沉积物的方法。

2. 发明授权

US5202126A Composition containing pregnenolone or a pregnenolone ester incorporated in liposomes, and a method for regenerating, or revitalizing the skin therewith 失效
标题翻译：含有孕烯醇酮或掺入脂质体中的孕烯醇酮的组合物，以及用于再生或使皮肤恢复活力的方法
公开(公告)号：US5202126A
公开(公告)日：1993-04-13
申请号：US737933
申请日：1991-07-29
申请人： Pierre Perrier , Gerard Redziniak , Patrice Andre
发明人： Pierre Perrier , Gerard Redziniak , Patrice Andre
IPC分类号： A61K8/14 , A61K8/63 , A61K9/127 , A61K31/57 , A61Q19/00 , A61Q19/08
CPC分类号： A61K31/57 , A61K8/14 , A61K8/63 , A61K9/127 , A61Q19/00 , A61Q19/08 , Y10S514/844
摘要： The present invention relates to a composition based on hydrated lipidic lamellar phases or on liposomes.In this composition, pregnenolone or a pregnenolone ester, such as, in particular, pregnenolone acetate, sulfate or palmitate, is at least partially incorporated in the said hydrated lipidic lamellar phases or the said liposomes.This composition can be applied in particular in the cosmetic or pharmaceutical sector, especially the dermatological sector, for the preparation of compositions with regenerating or revitalizing activity.
摘要翻译：本发明涉及基于水合脂质层状相或在脂质体上的组合物。在该组合物中，孕烯醇酮或孕烯醇酮酯，特别是孕烯醇酮乙酸盐，硫酸盐或棕榈酸酯，至少部分地并入所述水合脂质层状相或所述脂质体中。该组合物可特别用于化妆品或制药领域，特别是皮肤病学领域，用于制备具有再生或活化活性的组合物。

3. 发明授权

US09012414B2 Cosmetic composition 有权
标题翻译：化妆品组成
公开(公告)号：US09012414B2
公开(公告)日：2015-04-21
申请号：US13639997
申请日：2011-04-14
申请人： Charlotte Simmler , Virginie Leplanquais , Emmanuelle Noblesse , Patrice Andre , Annelise Lobstein
发明人： Charlotte Simmler , Virginie Leplanquais , Emmanuelle Noblesse , Patrice Andre , Annelise Lobstein
IPC分类号： A61K31/7034 , A61K8/60 , A61K8/49 , A61Q19/08 , C07H15/203 , C07H1/08 , C07H15/207
CPC分类号： A61K8/602 , A61K8/498 , A61K31/7034 , A61Q19/08 , C07H1/08 , C07H15/203 , C07H15/207
摘要： The invention relates to novel eucomic acid (2-(4-hydroxybenzyl)malic acid) derivatives or plant extracts comprising such derivatives, and also to cosmetic or dermatological compositions containing these compounds or these extracts, and to cosmetic care methods using said compositions. Exemplary compounds are represented by formula (I) below: in which, with the proviso that R1, R2 and R3 are not simultaneously a hydrogen atom, R1 and R3 each independently represent a hydrogen atom or a saturated or unsaturated, preferably C1-C12, hydrocarbon-based chain comprising an aromatic group, preferably a phenyl, said aromatic group being preferably substituted with a group comprising a sugar, preferably a monosaccharide or disaccharide, said chain optionally also comprising one or more heteroatoms preferably chosen from O, S and N, and R2 represents a hydrogen atom or a sugar, preferably a monosaccharide or disaccharide, said sugar being optionally substituted, in particular with a residue comprising a saturated or unsaturated, preferably C1-C12, hydrocarbon-based chain itself comprising an aromatic group, preferably a phenyl, said hydrocarbon-based chain optionally also comprising one or more heteroatoms preferably chosen from O, S and N.
摘要翻译：本发明涉及包含这些衍生物的新型的泛酸（2-（4-羟基苄基）苹果酸）衍生物或植物提取物，以及含有这些化合物或这些提取物的化妆品或皮肤病学组合物以及使用所述组合物的化妆品护理方法。示例性化合物由下式（I）表示：其中，条件是R1，R2和R3不同时为氢原子，R1和R3各自独立地表示氢原子或饱和或不饱和的，优选C1-C12，优选苯基的所述芳族基团优选被包含糖，优选单糖或二糖的基团取代，所述链任选还包含一个或多个优选选自O，S和N的杂原子，并且R 2表示氢原子或糖，优选单糖或二糖，所述糖任选被取代，特别是与包含饱和或不饱和的，优选C 1 -C 12的基于烃的链本身包含芳族基团的残基，优选为苯基，所述烃基链任选还包含一个或多个优选选自O，S和N的杂原子。

4. 发明申请

US20140024101A1 METHOD FOR INCREASING THE REPLICATION CAPACITY OF AN INFLUENZA VIRUS IN CULTURED CELLS 审中-公开
标题翻译：增加培养细胞中流感病毒的复制能力的方法
公开(公告)号：US20140024101A1
公开(公告)日：2014-01-23
申请号：US14110203
申请日：2012-04-10
申请人： Vincent Lotteau , Benoit De Chassey , Patrice Andre , Laurene Meyniel-Schicklin , Anne Aublin-Gex
发明人： Vincent Lotteau , Benoit De Chassey , Patrice Andre , Laurene Meyniel-Schicklin , Anne Aublin-Gex
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , A61K31/435 , C12N2760/16151
摘要： The present invention relates to methods for increasing the replication capacity of an influenza virus in cultured cells. More particularly, the present invention relates to a method for increasing the replication capacity of an influenza virus in a cell comprising the steps consisting of i) infecting said cell with said influenza virus and ii) culturing said infected cell with a least one molecule selected from the group consisting of Dibucaine, Aprindine, Amiloride, Mevinolin, Simvastatin, Promathazine, Pranlukast, Nimodipine, Ibutilide hemifumarate Salt, Risperidone and derivatives or analogues thereof.
摘要翻译：本发明涉及提高培养细胞中流感病毒复制能力的方法。更具体地说，本发明涉及增加细胞中流感病毒的复制能力的方法，包括以下步骤：i）用所述流感病毒感染所述细胞，和ii）用至少一种选自以下的分子培养所述感染细胞：包括迪布卡因，奥林定宁，阿米洛利，米维林，辛伐他汀，普拉那嗪，普兰司他，尼莫地平，伊碧替利半富马酸盐，利培酮及其衍生物或类似物。

5. 发明授权

US08216556B2 Coloring material and its uses, in particular in the field of cosmetics, especially for making up the skin and superficial body growths 有权
标题翻译：着色材料及其用途，特别是在化妆品领域，特别是用于补充皮肤和表面的身体生长
公开(公告)号：US08216556B2
公开(公告)日：2012-07-10
申请号：US12706863
申请日：2010-02-17
申请人： Patrice Andre , Elodie Verdier , Michel Garcia
发明人： Patrice Andre , Elodie Verdier , Michel Garcia
IPC分类号： A61K8/00 , A61K8/81
CPC分类号： C09B61/00 , A61K8/25 , A61K8/97 , A61K2800/43 , A61Q1/02 , A61Q1/10 , A61Q3/02 , C09B63/005
摘要： The invention relates to a solid coloring material obtained by precipitation, in an aqueous medium, of the reaction product of an alkali metal silicate with a colored complex obtained by reaction, in aqueous solution, of a hydrolysable tannin or of a plant extract comprising it with a salt of a metal cation. The invention also relates to a cosmetic composition intended for making up the skin or superficial body growths comprising this coloring material. It also relates to a method for making up the skin or superficial body growths comprising the topical application of this cosmetic composition.
摘要翻译：本发明涉及一种固体着色材料，其通过在水性介质中沉淀碱金属硅酸盐与通过在水溶液中将水解性单宁或包含其的植物提取物与金属阳离子的盐。本发明还涉及用于构成包含该着色材料的皮肤或表面体生长的化妆品组合物。它还涉及一种用于构成皮肤或表面体生长的方法，其包括该化妆品组合物的局部应用。

6. 发明授权

US07776367B2 Use in the cosmetics field of an extract of an exsudate of the plant Daniella oliveri, in particular as an antiwrinkle agent 有权
标题翻译：在化妆品领域中使用植物丹参的渗出物提取物，特别是作为抗皱剂
公开(公告)号：US07776367B2
公开(公告)日：2010-08-17
申请号：US12217230
申请日：2008-07-02
申请人： Cécile Lamy , Nancy Sauvan , Isabelle Renimel , Patrice Andre , Sylvie Darnault
发明人： Cécile Lamy , Nancy Sauvan , Isabelle Renimel , Patrice Andre , Sylvie Darnault
IPC分类号： A61K36/00 , A61K9/00 , A61K47/00
CPC分类号： A61K8/97 , A61Q19/08
摘要： The invention relates to the use, in a cosmetic composition or for the production of a cosmetic composition, of an extract of an exudate of the plant Daniellia oliveri, said exudate being at least partially made up of the oleoresin of said plant.It relates most particularly to the use of this extract as a cosmetic agent for modifying the surface of the skin by giving it a smoother appearance through a reduction in the depth of the wrinkles and/or fine lines and/or by providing it with a re-plumping effect.It also relates to a cosmetic care method for modifying the surface of the skin by giving it a smoother appearance through a reduction in the depth of the wrinkles and fine lines and/or by providing it with a re-plumping effect, comprising the application, to the areas of the skin in question, of a cosmetic composition containing this extract.
摘要翻译：本发明涉及在化妆品组合物中或用于生产化妆品组合物中植物丹参的渗出物提取物的用途，所述渗出物至少部分地由所述植物的油树脂组成。它最特别地涉及使用这种提取物作为化妆品，以通过减少皱纹和/或细纹的深度和/或通过提供皱纹和/或细纹而使其更平滑的外观来改变皮肤的表面 - 效果。本发明还涉及一种美容护理方法，其通过减少皱纹和细纹的深度和/或通过使皱纹和细纹的深度赋予其更平滑的外观来改变皮肤的表面，涉及含有该提取物的化妆品组合物的所述皮肤区域。

7. 发明申请

US20090274760A1 Use of An Alkyl Glycoside Or Of A Mixture Of Alkyl Glycosides Having Anti-Ageing And/Or Calming Properties As Active Agents In Cosmetic Compositions, And Methods Of Cosmetic Care Using Said Compositions 有权
标题翻译：使用烷基糖苷或具有抗衰老和/或镇静作用的化合物作为活性剂的烷基糖苷的混合物在化妆品组合物中的应用，以及使用所述组合物的化妆品护理方法
公开(公告)号：US20090274760A1
公开(公告)日：2009-11-05
申请号：US12415058
申请日：2009-03-31
申请人： Nicolas Thiebault , Jean-Christophe Archambault , Patrice Andre , Florence Pilard , Vincent Moreau
发明人： Nicolas Thiebault , Jean-Christophe Archambault , Patrice Andre , Florence Pilard , Vincent Moreau
IPC分类号： A61K9/10 , A61K47/36
CPC分类号： A61K8/604 , A61K31/7032 , A61Q19/005 , A61Q19/08
摘要： The present invention relates to a novel use of alkyl glycosides and of mixtures of alkyl glycosides having anti-ageing and/or calming properties as active agents in cosmetic compositions, and to methods of cosmetic care using the said compositions.
摘要翻译：本发明涉及在化妆品组合物中具有抗衰老和/或镇静作用的烷基糖苷和烷基糖苷的混合物的新用途以及使用所述组合物的化妆品护理方法。

8. 发明申请

US20080176820A1 Use of L-alpha-lysophosphatidylcholine to obtain the differentiation of monocytes into mature dendritic cells in vitro 审中-公开
标题翻译：使用L-α-溶血磷脂酰胆碱在体外获得单核细胞分化成成熟树突状细胞
公开(公告)号：US20080176820A1
公开(公告)日：2008-07-24
申请号：US12076591
申请日：2008-03-20
申请人： Vincent Lotteau , Patrice Andre
发明人： Vincent Lotteau , Patrice Andre
IPC分类号： A61K31/685 , A61P29/00
CPC分类号： A61K31/4439 , A61K9/0019 , A61K47/10 , A61K47/24
摘要： The disclosure relates to a method for in vivo differentiation of monocytes in mature dendritic cells, wherein a) monocytes are provided in an appropriate culture medium, b) the monocycles are differentiated in dendritic cells in the presence of a differentiation factor, c) L-α-lysophosphatidylcholine is added to the medium and mature dendritic cells are obtained. The disclosure also relates to the use of at least one inhibitor of L-α-lysophosphatidylcholine in the production of a medicament for the prevention of an inflammation and/or in order to combat an inflammatory disease and/or autoimmune disease.
摘要翻译：本公开涉及成熟树突状细胞中单核细胞的体内分化方法，其中a）在合适的培养基中提供单核细胞，b）在分化因子存在下，单环在树突状细胞中分化，c）向培养基中加入α-溶血磷脂酰胆碱，得到成熟树突状细胞。本公开还涉及至少一种L-α-溶血磷脂酰胆碱抑制剂在制备用于预防炎症和/或用于抵抗炎性疾病和/或自身免疫疾病的药物中的用途。

9. 发明授权

US07259012B2 Use of oxidized lipoproteins for differentiation of precursor cells into mature dendritic cells 失效
标题翻译：使用氧化脂蛋白将前体细胞分化成成熟树突状细胞
公开(公告)号：US07259012B2
公开(公告)日：2007-08-21
申请号：US10482480
申请日：2002-07-08
申请人： Vincent Lotteau , Patrice Andre
发明人： Vincent Lotteau , Patrice Andre
IPC分类号： C12N5/00 , C12N5/06 , C12N5/08 , A61K47/44
CPC分类号： C12N5/0639 , A61K2039/5154 , C12N2500/36
摘要： The invention concerns a method for differentiating precursor cells into mature dendritic cells, comprising placing the precursor cells in a medium suitable for their differentiation and adding to the medium, in a predetermined amount, at least one fraction of oxidized lipoproteins selected among oxidized very low density lipoproteins (VLDLs) and/or oxidized intermediate density lipoproteins (IDLs) and/or oxidized low density lipoproteins (LDLs). The precursor cells are preferably monocytes.
摘要翻译：本发明涉及将前体细胞分化为成熟树突状细胞的方法，包括将前体细胞置于适于其分化的培养基中，并以预定量向培养基中加入至少一部分氧化的低密度脂蛋白脂蛋白（VLDL）和/或氧化的中密度脂蛋白（IDL）和/或氧化的低密度脂蛋白（LDL）。前体细胞优选为单核细胞。

10. 发明申请

US20050048138A1 Use of Rhodiola crenulata extract via the topical route 审中-公开
标题翻译：通过局部途径使用红景天提取物
公开(公告)号：US20050048138A1
公开(公告)日：2005-03-03
申请号：US10842904
申请日：2004-05-10
申请人： Eric Perrier , Sebastien Bonnet , Delphine Rival , Patrice Andre , Nancy About
发明人： Eric Perrier , Sebastien Bonnet , Delphine Rival , Patrice Andre , Nancy About
IPC分类号： A61K8/00 , A61K8/02 , A61K8/06 , A61K8/63 , A61K8/96 , A61K8/97 , A61K36/00 , A61K36/18 , A61K36/41 , A61P17/00 , A61P17/10 , A61P17/16 , A61P43/00 , A61Q1/00 , A61Q1/04 , A61Q1/10 , A61Q5/02 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61K35/78
CPC分类号： A61K36/41 , A61K8/97 , A61K9/0014 , A61K2800/28 , A61Q19/02 , A61Q19/08
摘要： The invention relates to the use of a Rhodiola crenulata extract, via the topical route, for increasing the energy metabolism of the cutaneous tissues of a subject. The invention relates notably to topical compositions which comprise an active agent for increasing the energy metabolism of the cutaneous tissues of a subject, said active agent being a Rhodiola crenulata extract. The present invention enables making a cosmetic care such as fighting against, or slowing down or preventing the loosening of the cutaneous tissue, increasing the plasticity of the cutaneous tissue, exerting an anti-wrinkle effect or slowing down or preventing the appearance of wrinkles, fighting against, slowing down or preventing the appearance of acne, exerting a depigmenting effect of the cutaneous tissue, in particular of the skin, and promoting desquamation of the cutaneous tissue (or “peeling”).
摘要翻译：本发明涉及红景天提取物通过局部途径用于增加受试者皮肤组织的能量代谢的用途。本发明特别涉及包含用于增加受试者的皮肤组织的能量代谢的活性剂的局部组合物，所述活性剂是红景天提取物。本发明能够进行化妆品护理，例如防止或减缓或防止皮肤组织的松动，增加皮肤组织的可塑性，发挥抗皱作用或减缓或防止皱纹的出现，起搏抵抗，减缓或防止痤疮的出现，发挥皮肤组织，特别是皮肤的脱色作用，促进皮肤组织的脱屑（或“剥离”）。

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