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    • 1. 发明申请
    • METHOD FOR IDENTIFICATION AND QUANTIFICATION OF POLYHERBAL FORMULATION INGREDIENTS
    • 鉴定和定量多种制剂成分的方法
    • WO2007099560A2
    • 2007-09-07
    • PCT/IN2007000080
    • 2007-03-01
    • PROMED EXPORTS PVT LTDCHAUHAN SATEESH KUMARBAHRI DEEPAK
    • CHAUHAN SATEESH KUMARBAHRI DEEPAK
    • A61K9/16A61K9/48A61K36/00
    • A61K9/48A61K9/16
    • The present invention provides a novel method useful for identifying and then quantifying individual active ingredients derived from natural source from poly herbal formulation, said method comprising of converting the individual active ingredients into pellets/spansules, optionally with pharmaceutically active excipients, coating the pellets of individual ingredients with acceptable food colour distinct from one another, mixing these different color pellets as per the formulation which can be filled either in hard gelatin capsule or can be suspended in syrup or may be dispensed in the form of granules only. The different colour pellets from the formulation can be visually separated with naked eye or with the help of magnifying lens from one another; thus provides physical separation of individual ingredients from poly herbal formulation, which can be weighted and divided by the factor equivalent to the excipients. Further confirmation (qualitative or quantitative) may be established by different analytical means as already known in the art such as solvent extractive values, spectrophotometer, chromatography, titrimetry, gravimetric, etc.
    • 本发明提供了一种新颖的方法,用于鉴定和定量来自多草药制剂的天然来源的单个活性成分,所述方法包括将单独的活性成分转化为丸粒/片剂,任选地与药物活性赋形剂一起,将个体 具有可接受食物颜色的成分彼此不同,根据可以填充在硬明胶胶囊中的制剂混合这些不同颜色的小丸,或者可以悬浮在糖浆中或可以仅以颗粒形式分配。 来自配方的不同颜色的颗粒可以用肉眼或借助于放大镜彼此在视觉上分离; 从而提供了聚草药制剂中单个成分的物理分离,其可以被加权并除以相当于赋形剂的因子。 进一步确认(定性或定量)可通过本领域已知的不同分析手段建立,例如溶剂提取值,分光光度计,色谱法,滴定仪,重量分析等。