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1. 发明申请

WO9920727A9 CLEANING COMPOSITIONS CONTAINING MULTIPLY-SUBSTITUTED PROTEASE VARIANTS 审中-公开
标题翻译：含有多取代蛋白质变体的清洁组合物
公开(公告)号：WO9920727A9
公开(公告)日：1999-09-02
申请号：PCT/US9822588
申请日：1998-10-23
申请人： PROCTER & GAMBLE , GENENCOR INT , GHOSH CHANCHAL KUMAR , BAECK ANDRE CESAR , OHTANI RYOHEI , BUSCH ALFRED , SHOWELL MICHAEL STANFORD , SCHELLENBERGER VOLKER , KELLIS JAMES T JR , PAECH CHRISTIAN , NADHERNY JOANNE , NAKI DONALD P , COLLIER KATHERINE D , CALDWELL ROBERT M , POULOSE AYROOKARAN J
发明人： GHOSH CHANCHAL KUMAR , BAECK ANDRE CESAR , OHTANI RYOHEI , BUSCH ALFRED , SHOWELL MICHAEL STANFORD , SCHELLENBERGER VOLKER , KELLIS JAMES T JR , PAECH CHRISTIAN , NADHERNY JOANNE , NAKI DONALD P , COLLIER KATHERINE D , CALDWELL ROBERT M , POULOSE AYROOKARAN J
IPC分类号： A23G4/00 , A23G4/12 , A61K8/66 , A61Q11/00 , C11D1/74 , C11D3/37 , C11D3/386 , C12N9/54 , A23G3/30 , A61K7/28 , A61K7/48
CPC分类号： A23G4/123 , A61K8/66 , A61Q11/00 , C11D1/74 , C11D3/3776 , C11D3/386 , C12N9/54 , C12Y304/21062
摘要： The present invention relates to cleaning compositions comprising a protease variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of Bacillus amyloliquefaciens subtilisin in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274 and 275 of Bacillus amyloliquefaciens subtilisin; wherein when said protease variant includes a substitution of amino acid residues positions corresponding to positions 103 and 76, there is also a substitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 of Bacillus amyloliquefaciens subtilisin; and one or more cleaning adjunct materials. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 of DOLLAR (Bacillus amyloliquefaciens) subtilisin; and one or more cleaning adjunct materials. Methods for using the cleaning compositions are also provided.
摘要翻译：本发明涉及包含蛋白酶变体的清洁组合物。一种清洁组合物包含蛋白酶变体，其包括氨基酸残基与对应于解淀粉芽孢杆菌枯草杆菌蛋白酶的位置103的氨基酸残基处的另一个天然存在的氨基酸残基的取代，以及氨基酸残基与另一天然存在的一个或多个对应于1,2,3,4,8,9,10,12,13,16,17,18,19,20,21,22,24,27,33， 37，38，42，43，48，55，57，58，61，62，68，72，75，76，77，78，79，86，87，89，97，98，99，101，102， 104，106，107，109，111，114，116，117，119，121，123，126，128，130，131，133，134，137，140，141，142，146， 160,166,167,170,173,174,177,181,182,183,184,185,188,192,194,198,203,204,205,206,209,210,211,212,213， 214,215,216,217,218,222,224,227,228,222,224,227,228,230,232,236,237,238,240,242,243,244,245,246,247,248,249,251,252,225,216,217,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224 253,254,25 5,256,257,258,259,260,261,262,263,265,268,269,270,271,272,274和275的解淀粉芽孢杆菌枯草杆菌蛋白酶; 其中当所述蛋白酶变体包括对位置103和76的氨基酸残基置换时，还有一个或多个除对应于位置27,99的氨基酸残基位置之外的氨基酸残基的氨基酸残基的取代，解淀粉芽孢杆菌枯草杆菌蛋白酶的101,104,107,109,123,128,166,204,206,210,216,217,218,222,260,265或274; 和一种或多种清洁辅助材料。另一种清洁组合物包含蛋白酶变体，其包括氨基酸残基与对应于DOLLAR（解淀粉芽孢杆菌）的位置62,212,230,232,252和257的一个或多个氨基酸残基处的另一个天然存在的氨基酸残基取代，枯草杆菌蛋白酶; 以及一种或多种清洁辅助材料。还提供了使用清洁组合物的方法。

2. 发明申请

WO9920723A2 MULTIPLY-SUBSTITUTED PROTEASE VARIANT AND AMYLASE VARIANT-CONTAINING CLEANING COMPOSITIONS 审中-公开
标题翻译：多种取代的蛋白质变体和淀粉含有变化的清洁组合物
公开(公告)号：WO9920723A2
公开(公告)日：1999-04-29
申请号：PCT/US9822486
申请日：1998-10-23
申请人： PROCTER & GAMBLE , GHOSH CHANCHAL KUMAR , BAECK ANDRE CESAR , OHTANI RYOHEI , BUSCH ALFRED , SHOWELL MICHAEL STANTON
发明人： GHOSH CHANCHAL KUMAR , BAECK ANDRE CESAR , OHTANI RYOHEI , BUSCH ALFRED , SHOWELL MICHAEL STANTON
IPC分类号： A23G4/00 , A23G4/12 , A23K1/165 , A61K8/00 , A61K8/25 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/44 , A61K8/46 , A61K8/60 , A61K8/64 , A61K8/66 , A61Q1/02 , A61Q1/14 , A61Q11/00 , A61Q11/02 , A61Q19/00 , A61Q19/10 , C11D3/386 , C11D3/395 , C11D7/42 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/50 , C12N9/54 , C12N9/56 , C12N9/58 , C12N15/09 , C12N15/57 , C12R1/07 , C11D
CPC分类号： C12N9/54 , A23G4/123 , A23K20/189 , A61K8/66 , A61K2800/86 , A61Q11/00 , A61Q19/00 , C11D3/386 , C11D3/38609 , C11D3/38618 , C11D3/3907 , C11D3/3945 , C12Y304/00 , C12Y304/21062
摘要： The present invention relates to cleaning compositions comprising a protease variant and an amylase variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of Bacillus amyloliquefaciens subtilisin in combination with a substitution at one or more other positions. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue position corresponding to positions 62, 212, 230, 232 and 257 of Bacillus amyloliquefaciens subtilisin. Method for using the cleaning composition is also provided.
摘要翻译：本发明涉及包含蛋白酶变体和淀粉酶变体的清洁组合物。一种清洁组合物包含蛋白酶变体，其包括在对应于解淀粉芽孢杆菌枯草杆菌蛋白酶的位置103的氨基酸残基位置处的氨基酸残基与另一个天然存在的氨基酸残基的取代以及在一个或多个其它位置的取代相结合。另一种清洁组合物包含蛋白酶变体，其包括氨基酸残基与对应于解淀粉芽孢杆菌枯草杆菌蛋白酶的位置62,212,230,232和257的一个或多个氨基酸残基处的另一个天然存在的氨基酸残基取代。还提供了使用清洁组合物的方法。

3. 发明申请

WO9920723A9 MULTIPLY-SUBSTITUTED PROTEASE VARIANT AND AMYLASE VARIANT-CONTAINING CLEANING COMPOSITIONS 审中-公开
标题翻译：多种取代的蛋白质变体和淀粉含有变化的清洁组合物
公开(公告)号：WO9920723A9
公开(公告)日：1999-09-02
申请号：PCT/US9822486
申请日：1998-10-23
申请人： PROCTER & GAMBLE , GHOSH CHANCHAL KUMAR , BAECK ANDRE CESAR , OHTANI RYOHEI , BUSCH ALFRED , SHOWELL MICHAEL STANTON
发明人： GHOSH CHANCHAL KUMAR , BAECK ANDRE CESAR , OHTANI RYOHEI , BUSCH ALFRED , SHOWELL MICHAEL STANTON
IPC分类号： A23G4/00 , A23G4/12 , A23K1/165 , A61K8/00 , A61K8/25 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/44 , A61K8/46 , A61K8/60 , A61K8/64 , A61K8/66 , A61Q1/02 , A61Q1/14 , A61Q11/00 , A61Q11/02 , A61Q19/00 , A61Q19/10 , C11D3/386 , C11D3/395 , C11D7/42 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/50 , C12N9/54 , C12N9/56 , C12N9/58 , C12N15/09 , C12N15/57 , C12R1/07 , C11D
CPC分类号： C12N9/54 , A23G4/123 , A23K20/189 , A61K8/66 , A61K2800/86 , A61Q11/00 , A61Q19/00 , C11D3/386 , C11D3/38609 , C11D3/38618 , C11D3/3907 , C11D3/3945 , C12Y304/00 , C12Y304/21062
摘要： The present invention relates to cleaning compositions comprising a protease variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of Bacillus amyloliquefaciens subtilisin in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274 and 275 of Bacillus amyloliquefaciens subtilisin; wherein when said protease variant includes a substitution of amino acid residues at positions corresponding to positions 103 and 76, there is also a substitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 of Bacillus amyloliquefaciens subtilisin; and one or more cleaning adjunct materials. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 of Bacillus amyloliquefaciens subtilisin; an amylase variant and one or more cleaning adjunct materials. Methods for using the cleaning compositions are also provided.
摘要翻译：本发明涉及包含蛋白酶变体的清洁组合物。一种清洁组合物包含蛋白酶变体，其包括氨基酸残基与对应于解淀粉芽孢杆菌枯草杆菌蛋白酶的位置103的氨基酸残基处的另一个天然存在的氨基酸残基的取代，以及氨基酸残基与另一个天然存在的在一个或多个对应于1,2,3,4,8,9,10,12,13,16,17,18,19,20,21,22,24,27,33， 37，38，42，43，48，55，57，58，61，62，68，72，75，76，77，78，79，86，87，89，97，98，99，101，102， 104，106，107，109，111，114，116，117，119，121，123，126，128，130，131，133，134，137，140，141，142，146，147， 160,166,167,170,173,174,177,181,182,183,184,185,188,192,194,188,203,204,205,206,209,210,211,212,213， 214,215,216,217,218,222,224,227,228,222,224,227,228,223,232,236,237,238,240,242,243,244,245,246,247,248,249,251,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,223,232 253,254,25 5,256,257,258,259,260,261,262,263,265,268,269,270,271,272,274和275的解淀粉芽孢杆菌枯草杆菌蛋白酶; 其中当所述蛋白酶变体包含氨基酸残基在对应于位置103和76的位置上的取代时，还存在氨基酸残基在一个或多个除对应于位置27的氨基酸残基位置之外的一个或多个氨基酸残基位置的取代， 99，101,104,107,109,123,128,166,204,206,210,216,217,218,222,260,265或274的解淀粉芽孢杆菌枯草杆菌蛋白酶; 和一种或多种清洁辅助材料。另一种清洁组合物包含蛋白酶变体，其包括氨基酸残基与对应于解淀粉芽孢杆菌枯草杆菌蛋白酶的位置62,212,230,232,252和257的一个或多个氨基酸残基处的另一个天然存在的氨基酸残基取代; 淀粉酶变体和一种或多种清洁辅助材料。还提供了使用清洁组合物的方法。

4. 发明申请

WO9920723A8 MULTIPLY-SUBSTITUTED PROTEASE VARIANT AND AMYLASE VARIANT-CONTAINING CLEANING COMPOSITIONS 审中-公开
标题翻译：多种取代的蛋白质变体和淀粉含有变化的清洁组合物
公开(公告)号：WO9920723A8
公开(公告)日：2001-03-08
申请号：PCT/US9822486
申请日：1998-10-23
申请人： PROCTER & GAMBLE , GHOSH CHANCHAL KUMAR , BAECK ANDRE CESAR , OHTANI RYOHEI , BUSCH ALFRED , SHOWELL MICHAEL STANTON
发明人： GHOSH CHANCHAL KUMAR , BAECK ANDRE CESAR , OHTANI RYOHEI , BUSCH ALFRED , SHOWELL MICHAEL STANTON
IPC分类号： A23G4/00 , A23G4/12 , A23K1/165 , A61K8/00 , A61K8/25 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/44 , A61K8/46 , A61K8/60 , A61K8/64 , A61K8/66 , A61Q1/02 , A61Q1/14 , A61Q11/00 , A61Q11/02 , A61Q19/00 , A61Q19/10 , C11D3/386 , C11D3/395 , C11D7/42 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/50 , C12N9/54 , C12N9/56 , C12N9/58 , C12N15/09 , C12N15/57 , C12R1/07 , A61K7/48
CPC分类号： C12N9/54 , A23G4/123 , A23K20/189 , A61K8/66 , A61K2800/86 , A61Q11/00 , A61Q19/00 , C11D3/386 , C11D3/38609 , C11D3/38618 , C11D3/3907 , C11D3/3945 , C12Y304/00 , C12Y304/21062
摘要： The present invention relates to cleaning compositions comprising a protease variant and an amylase variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of Bacillus amyloliquefaciens subtilisin in combination with a substitution at one or more other positions. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue position corresponding to positions 62, 212, 230, 232 and 257 of Bacillus amyloliquefaciens subtilisin. Method for using the cleaning composition is also provided.
摘要翻译：本发明涉及包含蛋白酶变体和淀粉酶变体的清洁组合物。一种清洁组合物包含蛋白酶变体，其包括在对应于解淀粉芽孢杆菌枯草杆菌蛋白酶的位置103的氨基酸残基位置处的氨基酸残基与另一个天然存在的氨基酸残基的取代以及在一个或多个其它位置的取代相结合。另一种清洁组合物包含蛋白酶变体，其包括氨基酸残基与对应于解淀粉芽孢杆菌枯草杆菌蛋白酶的位置62,212,230,232和257的一个或多个氨基酸残基处的另一个天然存在的氨基酸残基取代。还提供了使用清洁组合物的方法。

5. 发明申请

WO9815608A3 ALKOXYLATED, QUATERNIZED POLYAMINE DETERGENT INGREDIENTS 审中-公开
标题翻译：烷基化，季戊四醇清除剂成分
公开(公告)号：WO9815608A3
公开(公告)日：1998-05-22
申请号：PCT/US9717308
申请日：1997-10-01
申请人： PROCTER & GAMBLE , PANANDIKER RAJAN KESHAV , PRAMOD KAKUMANU , DE BUZZACCARINI FRANCESCO , KAHN JAY IAN , CONNOR DANIEL STEDHAM , KONG-CHAN JOSEPHINE LING , GOSSELINK EUGENE PAUL , OHTANI RYOHEI , YASUDA KINUKO , LEUPIN JENNIFER ANN , GHOSH CHANCHAL KUMAR
发明人： PANANDIKER RAJAN KESHAV , PRAMOD KAKUMANU , DE BUZZACCARINI FRANCESCO , KAHN JAY IAN , CONNOR DANIEL STEDHAM , KONG-CHAN JOSEPHINE LING , GOSSELINK EUGENE PAUL , OHTANI RYOHEI , YASUDA KINUKO , LEUPIN JENNIFER ANN , GHOSH CHANCHAL KUMAR
IPC分类号： C11D3/00 , C11D3/37 , C11D3/386
CPC分类号： C11D3/3792 , C11D3/0021 , C11D3/0036 , C11D3/37 , C11D3/3715 , C11D3/3719 , C11D3/3723 , C11D3/38618 , C11D3/38627
摘要： Quaternized alkylene polyamines, and mixtures thereof, are used in detergent compositions. 00000
摘要翻译：季铵化亚烷基多胺及其混合物用于洗涤剂组合物中。 00000

6. 发明申请

WO0024924A3 METHODS FOR SCREENING PROTEASE VARIANTS FOR USE IN DETERGENT COMPOSITIONS 审中-公开
标题翻译：用于筛选洗涤剂组合物中使用的蛋白酶变体的方法
公开(公告)号：WO0024924A3
公开(公告)日：2000-10-26
申请号：PCT/US9924822
申请日：1999-10-22
申请人： PROCTER & GAMBLE , GHOSH CHANCHAL KUMAR , BRODE PHILLIP FREDERICK III , RAUCH DEBORAH SUSAN , SHOWELL MICHAEL STANFORD
发明人： GHOSH CHANCHAL KUMAR , BRODE PHILLIP FREDERICK III , RAUCH DEBORAH SUSAN , SHOWELL MICHAEL STANFORD
IPC分类号： C12N15/01 , C11D3/386 , C12N9/54 , C12Q1/37 , C12R1/07
CPC分类号： C12Q1/37 , C11D3/386 , C12N9/54
摘要： Methods for screening protease variants for use in detergent systems are provided. Such methods relate to the net charge of the substitutions of the protease variants and the adsorption properties of the protease variants. Also included are detergent compositions comprising protease variants screened by such methods.
摘要翻译：提供了筛选用于洗涤剂体系的蛋白酶变体的方法。这些方法涉及蛋白酶变体取代的净电荷和蛋白酶变体的吸附性质。还包括包含通过这些方法筛选的蛋白酶变体的洗涤剂组合物。

7. 发明申请

WO9815607A2 ALKOXYLATED, QUATERNIZED DIAMINE DETERGENT INGREDIENTS 审中-公开
标题翻译：烷基化，定量DIAMINE洗涤剂成分
公开(公告)号：WO9815607A2
公开(公告)日：1998-04-16
申请号：PCT/US9717309
申请日：1997-09-24
申请人： PROCTER & GAMBLE , KAHN JAY IAN , PRAMOD KAKUMANU , LEUPIN JENNIFER ANN , CONNOR DANIEL STEDHAM , YASUDA KINUKO , PANANDIKER RAJAN KESHAV , BUZZACCARINI FRANCESCO DE , KONG CHAN JOSEPHINE LING , GOSSELINK EUGENE PAUL , OHTANI RYOHEI , GHOSH CHANCHAL KUMAR
发明人： KAHN JAY IAN , PRAMOD KAKUMANU , LEUPIN JENNIFER ANN , CONNOR DANIEL STEDHAM , YASUDA KINUKO , PANANDIKER RAJAN KESHAV , DE BUZZACCARINI FRANCESCO , KONG-CHAN JOSEPHINE LING , GOSSELINK EUGENE PAUL , OHTANI RYOHEI , GHOSH CHANCHAL KUMAR
IPC分类号： C11D3/00 , C11D3/37 , C11D3/386 , C11D1/62
CPC分类号： C11D3/3715 , C11D3/0021 , C11D3/0036 , C11D3/37 , C11D3/3719 , C11D3/3723 , C11D3/3792 , C11D3/38618 , C11D3/38627
摘要： Quaternized alkylene diamines, and mixtures thereof, are used in detergent compositions.
摘要翻译：季铵化亚烷基二胺及其混合物用于洗涤剂组合物中。

9. 发明申请

WO2005023131A3 ILLUMINATED ELECTRIC TOOTHBRUSHES 审中-公开
标题翻译：照亮电动牙刷
公开(公告)号：WO2005023131A3
公开(公告)日：2005-05-12
申请号：PCT/US2004029334
申请日：2004-09-09
申请人： PROCTER & GAMBLE , PINYAYEV ALEKSEY MIKHAILOVICH , GHOSH CHANCHAL KUMAR , CHAN JOHN GEOFFREY , PING WANG
发明人： PINYAYEV ALEKSEY MIKHAILOVICH , GHOSH CHANCHAL KUMAR , CHAN JOHN GEOFFREY , PING WANG
IPC分类号： A46B15/00 , A61C1/08 , A61C17/22 , A61C17/34 , A61C19/06 , A61N5/06 , H01L25/075
CPC分类号： A61C17/222 , A46B15/0002 , A46B15/0036 , A46B2200/1066 , A61C1/088 , A61C17/22 , A61C17/3436 , A61C17/349 , A61C19/063 , A61C19/066 , A61N5/0601 , A61N5/062 , A61N2005/0606 , A61N2005/0651 , H01L2224/48091 , H01L2224/48247 , H01L2224/49113 , H01L2924/00014
摘要： An illuminated electric toothbrush comprising a light emitting diode emitting light having a flux density of at least about 30 mW/cm . An illuminated electric toothbrush having this level of flux density can result in an oral care benefit such as whitening. When this toothbrush is used within the oral cavity the heat generated by the toothbrush remains low enough that the surface temperature of the teeth remains below about 43 °C. The flux density of at least about 30 MW/CM can be achieved by overpowering the light emitting diode, by using a light emitting diode having at least about two dices, and by providing a pulsed or non-continuous current to the LED which results in a pulsing or non-continuous light.
摘要翻译：一种发光的电动牙刷，包括发射具有至少约30mW / cm 2的通量密度的光的发光二极管。具有这种通量密度水平的照明电动牙刷可以导致口腔护理益处，例如美白。当这种牙刷在口腔内使用时，由牙刷产生的热量保持足够低，使得牙齿的表面温度保持在约43℃以下。至少约30MW / CM 2的通量密度可以通过使发光二极管功率过大，通过使用具有至少约两个骰子的发光二极管以及通过向LED提供脉冲或不连续电流来实现这导致脉冲或不连续的光。

10. 发明申请

WO2014047507A3 COMPOSITIONS AND ARTICLES HAVING A PARENT FRAGRANCE AND MICROCAPSULES ENCAPSULATING A NON-PARENT FRAGRANCE 审中-公开
标题翻译：包含芳香剂和微胶囊的组合物和制品包裹非芳香族香料
公开(公告)号：WO2014047507A3
公开(公告)日：2014-10-09
申请号：PCT/US2013061030
申请日：2013-09-20
申请人： PROCTER & GAMBLE , GHOSH CHANCHAL KUMAR , ZIMMERMAN DEAN ARTHUR
发明人： GHOSH CHANCHAL KUMAR , ZIMMERMAN DEAN ARTHUR , LI JIANJUN JUSTIN , DIHORA JITEN ODHAVJI , CETTI JONATHAN ROBERT , WITT STEVEN EDWARD , HUTCHINS VIRGINIA TZUNG-HWEI , FLICKINGER MARC ADAM , LABITZKE KEVIN MAX , DUBOIS ZERLINA GUZDAR
IPC分类号： A61K8/37 , A61K8/02 , A61K8/58 , A61K8/89 , A61Q13/00
CPC分类号： A61K8/11 , A61K8/0283 , A61K8/8152 , A61K2800/31 , A61K2800/412 , A61K2800/56 , A61K2800/624 , A61Q13/00 , A61Q15/00
摘要： A composition having a parent fragrance and microcapsules encapsulating another fragrance; and methods related thereto.
摘要翻译：一种具有母体香味的组合物和封装另一种香料的微胶囊; 和与其相关的方法。

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