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1. 发明申请

WO2008048614A8 METHODS AND TARGETS FOR IDENTIFYING MATERIALS FOR REGULATING HYPER-PROLIFERATIVE SKIN CONDITIONS 审中-公开
标题翻译：鉴定用于调节高增生性皮肤病症的材料的方法和目标
公开(公告)号：WO2008048614A8
公开(公告)日：2008-07-31
申请号：PCT/US2007022098
申请日：2007-10-16
申请人： PROCTER & GAMBLE , DAWSON THOMAS LARRY JR , SAUNDERS CHARLES WINSTON , XU JUN , GRANT RAYMOND ALAN
发明人： DAWSON THOMAS LARRY JR , SAUNDERS CHARLES WINSTON , XU JUN , GRANT RAYMOND ALAN
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6895 , C07K14/375 , C12Q1/6883 , C12Q2600/136 , C12Q2600/158 , G01N33/5008 , G01N2500/04
摘要： The present invention provides methods for identifying genes and proteins that can help regulate proliferative skin conditions caused, at least in part, by Malassezia restricta, including hyper-proliferative skin conditions. The genes identified may be used as markers for the condition onset and progression and to measure efficacy of a treatment. The present invention also provides methods to screen agents that are capable of regulating proliferative skin conditions, including hyper-proliferative skin conditions. The present invention also provides methods of identifying cosmetic and/or therapeutic materials that may cosmetically affect or treat various conditions by regulating the expression and activity of genes and proteins identified.
摘要翻译：本发明提供用于鉴定可以帮助调节至少部分由限制性马拉色氏菌引起的增生性皮肤病症的基因和蛋白质的方法，所述方法包括超增殖皮肤病症。所鉴定的基因可用作病症发作和进展的标志物并测量治疗的功效。本发明还提供了能够调节增殖性皮肤状况的筛选剂的方法，包括超增殖皮肤病症。本发明还提供了通过调节所鉴定的基因和蛋白质的表达和活性来鉴定可能美容地影响或治疗各种病症的化妆品和/或治疗材料的方法。

2. 发明申请

WO2014152086A8 METHOD OF MEASURING THE METABOLIC INDICATORS OF HAIR FOLLICLES 审中-公开
标题翻译：测量头发代谢指标的方法
公开(公告)号：WO2014152086A8
公开(公告)日：2015-09-24
申请号：PCT/US2014026933
申请日：2014-03-14
申请人： PROCTER & GAMBLE
发明人： HULETTE BEN CHARLTON , DAWSON THOMAS LARRY JR
IPC分类号： A61B5/00 , G01N33/497 , G01N33/50
CPC分类号： G01N33/5088 , A61B5/448 , G01N33/5038
摘要： A method of measuring the effect of an active agent or a stressor on the baseline metabolic indicators of one or more hair follicles, the method including (a) obtaining one or more hair follicles; (b) placing the one or more hair follicles in a vessel, wherein the one or more hair follicles are positioned under one or more sensors; (c) using the one or more sensors to measure the one or more hair follicles' baseline metabolic indicators for both glycolysis and oxidative phosphorylation; (d) exposing the one or more hair follicles to an active agent or a stressor; and (e) using the one or more sensors to measure the one or more hair follicles' respondent metabolic indicators for both glycolysis and oxidative phosphorylation.
摘要翻译：一种测量活性剂或应激源对一种或多种毛囊的基线代谢指标的影响的方法，所述方法包括（a）获得一种或多种毛囊; （b）将一个或多个毛囊放置在血管中，其中所述一个或多个毛囊位于一个或多个传感器下方; （c）使用一个或多个传感器来测量一种或多种毛囊的糖酵解和氧化磷酸化的基准代谢指标; （d）将一种或多种毛囊暴露于活性剂或应激源; 和（e）使用一个或多个传感器来测量糖酵解和氧化磷酸化的一个或多个毛囊的应答代谢指标。

3. 发明申请

WO2008048614A9 METHODS AND TARGETS FOR IDENTIFYING MATERIALS FOR REGULATING HYPER-PROLIFERATIVE SKIN CONDITIONS 审中-公开
标题翻译：鉴定用于调节高增生性皮肤病症的材料的方法和目标
公开(公告)号：WO2008048614A9
公开(公告)日：2009-04-02
申请号：PCT/US2007022098
申请日：2007-10-16
申请人： PROCTER & GAMBLE , DAWSON THOMAS LARRY JR , SAUNDERS CHARLES WINSTON , XU JUN , GRANT RAYMOND ALAN
发明人： DAWSON THOMAS LARRY JR , SAUNDERS CHARLES WINSTON , XU JUN , GRANT RAYMOND ALAN
IPC分类号： C07K14/375 , G01N33/50
CPC分类号： C12Q1/6895 , C07K14/375 , C12Q1/6883 , C12Q2600/136 , C12Q2600/158 , G01N33/5008 , G01N2500/04
摘要： The present invention provides methods for identifying genes and proteins that can help regulate proliferative skin conditions caused, at least in part, by Malassezia restricta, including hyper-proliferative skin conditions. The genes identified may be used as markers for the condition onset and progression and to measure efficacy of a treatment. The present invention also provides methods to screen agents that are capable of regulating proliferative skin conditions, including hyper-proliferative skin conditions. The present invention also provides methods of identifying cosmetic and/or therapeutic materials that may cosmetically affect or treat various conditions by regulating the expression and activity of genes and proteins identified.

4. 发明申请

WO2009135006A3 METHODS FOR PREVENTING OXIDATIVE DAMAGE TO HAIR AND PROMOTE HAIR SHINE 审中-公开
标题翻译：用于预防氧化皮肤发炎和促进头发发炎的方法
公开(公告)号：WO2009135006A3
公开(公告)日：2011-05-19
申请号：PCT/US2009042317
申请日：2009-04-30
申请人： PROCTER & GAMBLE , DAWSON THOMAS LARRY JR , YOUNGQUIST ROBERT SCOTT , FISHER BRIAN KEITH
发明人： DAWSON THOMAS LARRY JR , YOUNGQUIST ROBERT SCOTT , FISHER BRIAN KEITH
IPC分类号： A61K8/04 , A61K8/42 , A61K8/49 , A61K8/67 , A61Q5/00 , A61Q5/02 , A61Q5/12
CPC分类号： A61K8/673 , A61K8/046 , A61K8/49 , A61K8/4933 , A61K8/675 , A61K2800/522 , A61Q5/00 , A61Q5/02 , A61Q5/065 , A61Q5/12
摘要： Hair care compositions and methods, that can prevent oxidative damage to hair. Such compositions comprise a follicular fungi reduction agent ("FFRA") and can be applied to any areas where the appearance of less oxidative damage is desired, such as the scalp or face. The present invention also relates to methods of promoting hair shine by using such compositions.
摘要翻译：护发组合物和方法，可以防止对头发的氧化损伤。这样的组合物包括滤泡真菌还原剂（“FFRA”），并且可以应用于需要较少氧化损伤的外观的任何区域，例如头皮或脸部。本发明还涉及通过使用这种组合物促进头发光泽的方法。

5. 发明申请

WO2008066612A8 METHODS AND TARGETS FOR INDENTIFYING MATERIALS FOR REGULATING HYPER-PROLIFERATIVE SKIN CONDITIONS 审中-公开
标题翻译：用于调节高增生皮肤条件的材料的方法和目标
公开(公告)号：WO2008066612A8
公开(公告)日：2008-12-11
申请号：PCT/US2007022097
申请日：2007-10-16
申请人： PROCTER & GAMBLE , DAWSON THOMAS LARRY JR , SAUNDERS CHARLES WINSTON , XU JUN , GRANT RAYMOND ALAN
发明人： DAWSON THOMAS LARRY JR , SAUNDERS CHARLES WINSTON , XU JUN , GRANT RAYMOND ALAN
IPC分类号： G01N33/50
CPC分类号： G01N33/5743 , G01N2500/00

6. 发明申请

WO2013096611A3 COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF AGING HAIR 审中-公开
标题翻译：用于改善老化发胶外观的组合物和方法
公开(公告)号：WO2013096611A3
公开(公告)日：2014-01-16
申请号：PCT/US2012070925
申请日：2012-12-20
申请人： PROCTER & GAMBLE
发明人： RICHARDS JEANETTE ANTHEA , DAWSON THOMAS LARRY JR , COMBS MARY JANE , DUEVA-KOGANOV OLGA , KOGANOV MICHAEL
IPC分类号： A61Q5/00 , A61K8/97
CPC分类号： A61K8/97 , A61K2800/5922 , A61Q5/00
摘要： A hair care composition and method of using the composition is provided that can increase the appearance of thicker and/or fuller hair and/or delay the appearance of gray hair to provide healthy and younger looking hair.
摘要翻译：提供使用该组合物的头发护理组合物和方法，其可以增加更厚和/或更丰满的头发的外观和/或延迟灰色头发的外观以提供健康和更年轻的头发。

7. 发明申请

WO2012087779A2 HAIR CARE COMPOSITIONS AND METHODS TO IMPROVE HAIR APPEARANCE 审中-公开
标题翻译：毛发护理组合物和改善毛发外观的方法
公开(公告)号：WO2012087779A2
公开(公告)日：2012-06-28
申请号：PCT/US2011065345
申请日：2011-12-16
申请人： PROCTER & GAMBLE , DAWSON THOMAS LARRY JR , YOUNGQUIST ROBERT SCOTT , RICHARDS JEANETTE ANTHEA , XIE SANCAI , COMBS MARY JANE
发明人： DAWSON THOMAS LARRY JR , YOUNGQUIST ROBERT SCOTT , RICHARDS JEANETTE ANTHEA , XIE SANCAI , COMBS MARY JANE
IPC分类号： A61N1/37
CPC分类号： A61Q7/00 , A61K8/42 , A61K8/4953 , A61K8/498 , A61K8/675 , A61Q5/002
摘要： Hair care compositions and methods that can increase the appearance of healthier hair by increasing the appearance of thicker and fuller hair, longer hair, and/or delayed emergence of gray hair. Such compositions can be applied to any areas where healthier hair appearance is desired, such as the scalp or face.
摘要翻译：头发护理组合物和方法，其通过增加更浓密和更饱满的头发，更长的头发和/或灰发延迟出现的外观来增加更健康的头发的外观。这种组合物可以应用于需要更健康的头发外观的任何区域，例如头皮或面部。

8. 发明申请

WO2008027541A3 HAIR CARE COMPOSITIONS THAT CAN INCREASE THE APPEARANCE OF THICKER AND FULLER HAIR 审中-公开
标题翻译：头发护理组合物可以增加厚度和充分发胶的外观
公开(公告)号：WO2008027541A3
公开(公告)日：2008-10-09
申请号：PCT/US2007019180
申请日：2007-08-30
申请人： PROCTER & GAMBLE , DAWSON THOMAS LARRY JR , OBLONG JOHN ERICH , YOUNGQUIST ROBERT SCOTT , XIE SANCAI
发明人： DAWSON THOMAS LARRY JR , OBLONG JOHN ERICH , YOUNGQUIST ROBERT SCOTT , XIE SANCAI
IPC分类号： A61K8/49 , A61K8/42 , A61K8/67 , A61Q7/00
CPC分类号： A61Q5/12 , A61K8/42 , A61K8/4953 , A61K8/675 , A61Q5/002 , A61Q7/00 , A61Q7/02 , G06Q30/0225
摘要： Hair care compositions, methods, and articles of commerce that can increase the appearance of thicker and fuller hair. Such compositions can be applied to any areas where a thicker and fuller hair appearance is desired, such as the scalp or face. The present invention also relates to methods of marketing such compositions.
摘要翻译：头发护理组合物，方法和商品，可以增加更厚和更丰满的头发的外观。这样的组合物可以应用于需要更厚和更丰满的头发外观的任何区域，例如头皮或面部。本发明还涉及营销这种组合物的方法。

9. 发明申请

WO2013184908A3 SYSTEMS AND METHODS FOR IDENTIFYING COSMETIC AGENTS FOR HAIR/SCALP CARE COMPOSITIONS 审中-公开
标题翻译：用于鉴定头发/护肤组合物的化妆品的系统和方法
公开(公告)号：WO2013184908A3
公开(公告)日：2014-04-17
申请号：PCT/US2013044497
申请日：2013-06-06
申请人： PROCTER & GAMBLE
发明人： XU JUN , BINDER ROBERT LLOYD , YOUNGQUIST ROBERT SCOTT , HU PING , DICOLANDREA THERESA , DAWSON THOMAS LARRY JR , HOWARD BRIAN WILSON
IPC分类号： G06F19/20 , G06F19/18
CPC分类号： C12Q1/6837 , G06F19/18 , G06F19/20
摘要： Provided are methods and systems for determining functional relationships between a cosmetic agent and a hair biology condition of interest. Also provided are methods and systems for identifying cosmetic agents that affect a hair biology condition, as well as the use of agents identified by such methods and systems for the preparation of cosmetic compositions, personal care products, or both.
摘要翻译：提供了用于确定化妆品和感兴趣的毛发生物学条件之间的功能关系的方法和系统。还提供了用于鉴定影响毛发生物学条件的化妆品的方法和系统，以及由这些方法和系统鉴定的用于制备化妆品组合物，个人护理产品或两者的试剂的使用。

10. 发明申请

WO2013096736A3 COMPOSITIONS AND METHODS FOR TREATING SKIN 审中-公开
标题翻译：用于治疗皮肤的组合物和方法
公开(公告)号：WO2013096736A3
公开(公告)日：2014-01-16
申请号：PCT/US2012071180
申请日：2012-12-21
申请人： PROCTER & GAMBLE
发明人： RICHARDS JEANETTE ANTHEA , DAWSON THOMAS LARRY JR , COMBS MARY JANE , DUEVA-KOGANOV OLGA , KOGANOV MICHAEL
IPC分类号： A61K8/97 , A61Q19/04 , A61Q19/08
CPC分类号： A61K36/82 , A61K8/97 , A61K36/03 , A61K36/23 , A61K36/28 , A61Q19/04 , A61Q19/08 , A61K2300/00
摘要： The present invention relates to skin care compositions comprising blends of camellia and feverfew serum fractions and/or kelp and parsley serum fractions. The skin care compositions also comprise a dermatologically acceptable carrier. The invention also relates to methods for increasing melanin production in skin by topically applying the skin care composition to areas in order to stimulate one or more steps in melanin synthesis and/or interrupt an inflammatory cycle.
摘要翻译：本发明涉及皮肤护理组合物，其包含山茶和发热血清级分和/或海带和荷兰芹血清级分的混合物。皮肤护理组合物还包含皮肤病学可接受的载体。本发明还涉及通过将皮肤护理组合物局部施用于区域以刺激黑色素合成中的一个或多个步骤和/或中断炎性循环来增加皮肤黑色素产生的方法。

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