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1. 发明申请

WO2009120254A1 SURFACES, INCLUDING MICROFLUIDIC CHANNELS, WITH CONTROLLED WETTING PROPERTIES 审中-公开
标题翻译：表面，包括微流通道，具有受控的润湿性能
公开(公告)号：WO2009120254A1
公开(公告)日：2009-10-01
申请号：PCT/US2009/000850
申请日：2009-02-11
申请人： PRESIDENT AND FELLOWS OF HARVARD COLLEGE , ABATE, Adam, R. , KRUMMEL, Amber, T. , HOLTZE, Christian , WEITZ, David, A.
发明人： ABATE, Adam, R. , KRUMMEL, Amber, T. , HOLTZE, Christian , WEITZ, David, A.
IPC分类号： B81B1/00 , B01F13/00 , B01J19/00
CPC分类号： F16L9/14 , B01F3/0807 , B01F13/0062 , B01J2219/00619 , B01J2219/00635 , B01J2219/00637 , B01L3/502707 , B81B2201/058 , B81B2203/0338 , B81C1/00206
摘要： The present invention generally relates to coating materials, including photoactive coating materials. In some aspects of the invention, a sol-gel is provided that can be formed as a coating on a microfluidic channel. One or more portions of the sol-gel can be reacted to alter its hydrophobicity, in some cases. For instance, in one set of embodiments, a portion of the sol-gel may be exposed to light, such as ultraviolet light, which can be used to induce a chemical reaction in the sol-gel that alters its hydrophobicity. In one set of embodiments, the sol-gel can include a photoinitiator, that upon exposure to light, produces radicals. Optionally, the photoinitiator may be conjugated to a silane or other material within the sol-gel. The radicals so produced may be used to cause a polymerization reaction to occur on the surface of the sol-gel, thus altering the hydrophobicity of the surface. In some cases, various portions may be reacted or left unreacted, e.g., by controlling exposure to light (for instance, using a mask). Such treated surfaces within a microfluidic channel may be useful in a wide variety of applications, for instance, in the creation of emulsions such as multiple emulsions.
摘要翻译：本发明一般涉及涂料，包括光活性涂料。在本发明的一些方面，提供可以形成为微流体通道上的涂层的溶胶 - 凝胶。在一些情况下，溶胶 - 凝胶的一个或多个部分可以反应以改变其疏水性。例如，在一组实施方案中，溶胶 - 凝胶的一部分可以暴露于光，例如紫外光，其可用于在溶胶 - 凝胶中诱导改变其疏水性的化学反应。在一组实施方案中，溶胶 - 凝胶可以包括光引发剂，其在暴露于光时产生自由基。任选地，光引发剂可以与溶胶 - 凝胶内的硅烷或其它材料缀合。这样生成的基团可以用于在溶胶 - 凝胶的表面上发生聚合反应，从而改变表面的疏水性。在一些情况下，例如通过控制曝光（例如，使用掩模），各种部分可以反应或未反应。微流体通道内的这样处理的表面可用于多种应用中，例如在产生诸如多重乳液的乳液中。

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