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    • 8. 发明申请
    • CAPSULES FROM SEPARATED POLYMER SOLUTIONS
    • 分离聚合物溶液的胶囊
    • WO2008060154A1
    • 2008-05-22
    • PCT/NL2007/050568
    • 2007-11-15
    • Friesland Brands B.V.POORTINGA, Albert ThijsPRICKAERTS, Ramona Maria Henricus
    • POORTINGA, Albert ThijsPRICKAERTS, Ramona Maria Henricus
    • A23L1/00A61K9/48A61K9/50
    • A61K9/107A23C9/1307A23C19/09A23C2210/40A23L27/84A23P10/30A23V2002/00A61K9/1075A61K9/5089A23V2200/224A23V2250/54246A23V2250/5026A23V2250/54252A23V2250/51088
    • The invention relates to a method of preparing a double emulsion comprising a) preparing an emulsion comprising at least two liquid phases by bringing a first polymer (A) and a second polymer (B) into contact with each other in a solvent, wherein the concentrations of the polymers are chosen such that, upon bringing them into contact, a phase separation occurs, thereby forming drops of a first liquid phase in a second liquid phase, wherein, in the first phase, the weight concentration of the polymer A (C A ) is higher and the weight concentration of the polymer B (C B ) is lower than the respective concentrations in the second phase; b) dispersing the emulsion in a third liquid phase, which third phase comprises the polymer A in a C A which is higher than in the second phase and the polymer B in a C B which is lower than in the second phase, thereby forming the double emulsion, comprising at least one discontinuous phase (1) - with a relatively high C A and a relatively low C B — enclosed by a surrounding phase (2) — with a relatively low C A and a relatively high C B - which discontinuous and surrounding phase are dispersed in a continuous phase (3) - with a relatively high C A and a relatively low C B ; and wherein the solvent in said liquid phases is the same or the solvents are at least, in the absence of the polymers, soluble in one another or completely miscible at 25°C.
    • 本发明涉及一种制备双重乳液的方法,其包括:a)通过使第一聚合物(A)和第二聚合物(B)在溶剂中彼此接触来制备包含至少两个液相的乳液,其中浓度 选择聚合物,使得当它们接触时,发生相分离,从而在第二液相中形成第一液相的液滴,其中在第一相中聚合物A的重量浓度(C < SUB> A )较高,聚合物B(C B B)的重量浓度低于第二相中各自的浓度; b)将乳液分散在第三液相中,该第三相包含高于第二相的C A A中的聚合物A和C B中的聚合物B, SUB>其低于第二相,从而形成双重乳液,其包含至少一个不连续相(1) - 具有相对较高的C A和更低的C B, 由相邻的相(2)包围 - 具有相对较低的C A和相对高的C B - 不连续和周围的相分散在连续的 相(3) - 具有相对较高的C A和较低的C B; 并且其中所述液相中的溶剂相同或溶剂至少在不存在聚合物的情况下彼此相溶或在25℃完全混溶。