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2. 发明申请

WO2018013333A1 COMPOSITIONS AND METHODS TO CONTROL INSECT PESTS 审中-公开
标题翻译：控制昆虫害虫的组合物和方法
公开(公告)号：WO2018013333A1
公开(公告)日：2018-01-18
申请号：PCT/US2017/039374
申请日：2017-06-27
申请人： PIONEER HI-BRED INTERNATIONAL, INC.
发明人： DAVIS-VOGEL, Courtney , HU, Xu , NIU, Xiping , SETHI, Amit
IPC分类号： C12N15/113 , C12N15/82 , C07K14/435
CPC分类号： C12N15/8286 , C07K14/43563 , C12N15/8218 , Y02A40/162
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-398 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest. Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
摘要翻译：提供了使用沉默元件的方法和组合物，所述沉默元件当被植物害虫例如鞘翅目，半翅目或鳞翅目植物害虫摄取时，所述植物害虫包括Diabrotica，Leptinotarsa，Phyllotreta， Acyrthosiphan，Bemisia，Halyomorpha，Nezara或Spodoptera植物有害生物会降低害虫中靶序列的表达。公开了本文公开的SEQ ID NOS：1-398中任一个所示的各种靶多核苷酸或其变体和片段或其互补物，其中靶害虫中一个或多个序列的表达的降低控制害虫。还提供了包含本发明的沉默元件或其活性变体或片段的植物，植物部分，细菌和其他宿主细胞。

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