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1. 发明申请

WO2020076958A1 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE 审中-公开
公开(公告)号：WO2020076958A1
公开(公告)日：2020-04-16
申请号：PCT/US2019/055409
申请日：2019-10-09
申请人： PIONEER HI-BRED INTERNATIONAL, INC.
发明人： CERF, David Charles , GRUVER, Steven D , LIU, Lu , PARK, Young-Jun , SCHELLENBERGER, Ute , WEI, Jun-Zhi , XIE, Weiping , ZHU, Genhai
IPC分类号： C12N15/82 , C07K14/415
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

2. 发明申请

WO2017105987A1 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE 审中-公开
公开(公告)号：WO2017105987A1
公开(公告)日：2017-06-22
申请号：PCT/US2016/065531
申请日：2016-12-08
申请人： PIONEER HI-BRED INTERNATIONAL, INC. , E I DU PONT DE NEMOURS AND COMPANY
发明人： LIU, Lu , LUM, Amy , ORAL, Jarred Kenneth , PEREZ-ORTEGA, Claudia , ROSEN, Barbara Ann Marie , SCHELLENBERGER, Ute , WEI, Jun-Zhi , XIE, Weiping , ZHONG, Xiaohong , ZHU, Genhai
IPC分类号： C07K14/21 , C12N15/82 , C12R1/38 , A01N63/02
CPC分类号： C07K14/21 , A01N37/42 , A01N63/02 , C12N15/8286 , Y02A40/162
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

3. 发明申请

WO2018111551A1 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE 审中-公开
公开(公告)号：WO2018111551A1
公开(公告)日：2018-06-21
申请号：PCT/US2017/063702
申请日：2017-11-29
申请人： PIONEER HI-BRED INTERNATIONAL, INC.
发明人： GRUVER, Steven D. , LIU, Lu , ROSEN, Barbara , SCHELLENBERGER, Ute , WEI, Jun-Zhi , XIE, Weiping , ZHU, Genhai
IPC分类号： C07K14/21 , C12N15/82
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

4. 发明申请

WO2015038734A2 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE 审中-公开
公开(公告)号：WO2015038734A2
公开(公告)日：2015-03-19
申请号：PCT/US2014/055128
申请日：2014-09-11
申请人： PIONEER HI-BRED INTERNATIONAL, INC.
发明人： DIEHN, Scott , ENGLISH, James , LIU, Lu , ONG, Azalea , ORAL, Jarred , ROSEN, Barbara , SCHELLENBERGER, Ute , UDRANSZKY, Ingrid , WEI, Jun-zhi , XIE, Weiping , ZHU, Genhai
CPC分类号： A01N63/02 , C07K14/21 , C12N15/8286 , C12Q1/689 , C12Q2600/13 , G01N33/68 , G01N2333/21 , Y02A40/162
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

5. 发明申请

WO2020123242A1 BIOLOGICALS AND THEIR USE IN PLANTS 审中-公开
公开(公告)号：WO2020123242A1
公开(公告)日：2020-06-18
申请号：PCT/US2019/064579
申请日：2019-12-05
申请人： PIONEER HI-BRED INTERNATIONAL, INC.
发明人： COY, Monique , GRUVER, Steven D , KOZY, Heather , LIU, Lu , PARK, Young-Jun , ROSEN, Barbara , SCHELLENBERGER, Ute , WEI, Jun-Zhi , XIE, Weiping
IPC分类号： A01N63/14 , C07K14/195 , C07K14/21
摘要： Biological strains, compositions, and methods of using the strains and compositions for reducing overall insect damage.

6. 发明申请

WO2020055885A1 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE 审中-公开
公开(公告)号：WO2020055885A1
公开(公告)日：2020-03-19
申请号：PCT/US2019/050434
申请日：2019-09-10
申请人： PIONEER HI-BRED INTERNATIONAL, INC.
发明人： ALTIER, Daniel J. , BARRY, Jennifer Kara , BARTHOLOMAY, Christian , DONG, Hua , GERBER, Ryan Michael , GILLIAM, Jacob , GRUVER, Steven D. , LIU, Lu , ORAL, Jarred Kenneth , O'REAR, Jessica , SCHELLENBERGER, Ute , SCHEPERS, Eric , THORPE, Daniel James , WOLFE, Thomas Chad , XIE, Weiping , YALPANI, Nasser , YOU, You , ZHU, Genhai
IPC分类号： C07K14/195 , C07K14/21 , C12N15/82
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

7. 发明申请

WO2014008054A2 NOVEL INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE 审中-公开
标题翻译：新型杀虫蛋白及其使用方法
公开(公告)号：WO2014008054A2
公开(公告)日：2014-01-09
申请号：PCT/US2013/047760
申请日：2013-06-26
申请人： PIONEER HI-BRED INTERNATIONAL, INC. , CERF, David C. , ENGLISH, James J. , HENDRICK, Carol A. , LIU, Lu , ORAL, Jarred K. , PATTEN, Phillip A. , ROSEN, Barbara A. , SCHELLENBERGER, Ute , UDRANSZKY, Ingrid A. , WEI, Jun-Zhi , ZHU, Genhai
发明人： CERF, David C. , ENGLISH, James J. , HENDRICK, Carol A. , LIU, Lu , ORAL, Jarred K. , PATTEN, Phillip A. , ROSEN, Barbara A. , SCHELLENBERGER, Ute , UDRANSZKY, Ingrid A. , WEI, Jun-Zhi , ZHU, Genhai
IPC分类号： C07K14/21 , A01N43/50 , A61K45/06 , C07K16/12 , G01N33/68
CPC分类号： C07K14/21 , A01N43/50 , A61K45/06 , C07K16/1214 , C07K2319/24 , G01N33/68
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.
摘要翻译：提供了控制害虫的组合物和方法。该方法涉及用编码杀虫蛋白的核酸序列转化生物体。特别地，核酸序列可用于制备具有杀虫活性的植物和微生物。因此，提供了转化的细菌，植物，植物细胞，植物组织和种子。组合物是杀虫的核酸和细菌物种的蛋白质。这些序列用于构建表达载体，用于随后转化为感兴趣的生物体，作为分离其他同源（或部分同源的）基因的探针。杀虫蛋白用于控制，抑制生长或杀死鳞翅目，鞘翅目，dipteran，真菌，半翅目和线虫害虫种群，并用于生产具有杀虫活性的组合物。

8. 发明申请

WO2018084936A1 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE 审中-公开
公开(公告)号：WO2018084936A1
公开(公告)日：2018-05-11
申请号：PCT/US2017/051460
申请日：2017-09-14
申请人： PIONEER HI-BRED INTERNATIONAL, INC.
发明人： ALTIER, Daniel J. , BARRY, Jennifer Kara , GERBER, Ryan Michael , GRUVER, Steven D. , LIU, Lu , SCHELLENBERGER, Ute , WEI, Jun-Zhi , XIE, Weiping , YALPANI, Nasser , ZHU, Genhai
IPC分类号： C07K14/21 , C07K14/24 , C07K14/265
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

9. 发明申请

WO2016186986A1 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE 审中-公开
公开(公告)号：WO2016186986A1
公开(公告)日：2016-11-24
申请号：PCT/US2016/032273
申请日：2016-05-13
申请人： PIONEER HI BRED INTERNATIONAL INC
发明人： KOZY, Heather , ORAL, Jarred , SCHELLENBERGER, Ute , WEI, Jun-Zhi , XIE, Weiping , ZHONG, Xiaohong , ZHU, Genhai
IPC分类号： C12N15/82 , C07K14/195
CPC分类号： C12N15/8242 , C07K14/21 , C07K2319/21
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

10. 发明申请

WO2016144686A1 STRUCTURE BASED METHODS FOR MODIFICATION OF PIP-72 POLYPEPTIDES AND PIP-72 POLYPEPTIDES DERIVED THEREFROM 审中-公开
标题翻译：基于结构的PIP-72多肽和PIP-72多肽衍生物的修饰方法
公开(公告)号：WO2016144686A1
公开(公告)日：2016-09-15
申请号：PCT/US2016/020634
申请日：2016-03-03
申请人： PIONEER HI-BRED INTERNATIONAL, INC.
发明人： LIU, Lu , ORAL, Jarred Kenneth , POLAND, Brad , SCHELLENBERGER, Ute
IPC分类号： C12N15/82 , C07K14/415 , C07K14/21 , A01N65/00
CPC分类号： C07K14/21 , A01N63/02 , C12N15/8286 , Y02A40/162
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity. Structure based methods for engineering insecticidal proteins of the disclosure to have modified physical properties are provided.
摘要翻译：提供了控制害虫的组成和方法。该方法涉及用编码杀虫蛋白的核酸序列转化生物体。特别地，核酸序列可用于制备具有杀虫活性的植物和微生物。因此，提供了转化的细菌，植物，植物细胞，植物组织和种子。组合物是杀虫的核酸和细菌物种的蛋白质。这些序列用于构建表达载体，用于随后转化为感兴趣的生物体，包括植物，作为分离其他同源（或部分同源的）基因的探针。杀虫蛋白用于控制，抑制生长或杀死鳞翅目，鞘翅目，双翅目，真菌，半翅目和线虫害虫种群并生产具有杀虫活性的组合物。提供了具有改进的物理性质的本发明的用于工程化杀虫蛋白的基于结构的方法。

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